Miaomiao WangThe First Affiliated Hospital of Xi'an Jiaotong University · Department of Diagnostic Radiology
Miaomiao Wang
About
35
Publications
2,923
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
321
Citations
Introduction
Skills and Expertise
Publications
Publications (35)
Background
Neonates with immature auditory function (eg, weak/absent middle ear muscle reflex) could conceivably be vulnerable to noise‐induced hearing loss; however, it is unclear if neonates show evidence of hearing loss following MRI acoustic noise exposure.
Purpose
To explore the auditory effects of MRI acoustic noise in neonates.
Study Type...
Accurate segmentation of punctate white matter lesions (PWMLs) are fundamental for the timely diagnosis and treatment of related developmental disorders. Automated PWMLs segmentation from infant brain MR images is challenging, considering that the lesions are typically small and low-contrast, and the number of lesions may dramatically change across...
Objectives
Whether the alternation of the glymphatic system exists in neurodevelopmental disease still remains unclear. In this study, we investigated structural and functional changes in the glymphatic system in the treatment-naïve attention-deficit/hyperactivity disorder (ADHD) children by quantitatively measuring the Virchow-Robin spaces (VRS) v...
Accurate segmentation of punctate white matter lesions (PWMLs) are fundamental for the timely diagnosis and treatment of related developmental disorders. Automated PWMLs segmentation from infant brain MR images is challenging, considering that the lesions are typically small and low-contrast, and the number of lesions may dramatically change across...
Background
The enlarged perivascular Virchow-Robin space (VRS), which indicates a glymphatic system alternation, is very common in patients with neurodegenerative diseases. However, assessing those morphological changes in this region by using conventional techniques may be challenging. In this study, we investigated structural and functional chang...
Preterm infants show high risk for subsequent neurodevelopmental disability. Early developmental characterization of brain and neurobehavioral function is critical for identifying the high-risk infants, and thus guiding the necessary intervention. This paper aims to elaborate the early evolution of preterm sensorimotor function by exploring the pos...
White matter maturation has been characterized by diffusion tensor (DT) metrics. However, maturational processes and degrees are not fully investigated due to limitations of univariate approaches and limited specificity/sensitivity. Diffusion kurtosis imaging (DKI) provides kurtosis tensor (KT) and white matter tract integrity (WMTI) metrics, besid...
Background: Simple febrile seizures (SFS) and epilepsy are common seizures in childhood. However, the mechanism underlying SFS is uncertain, and the presence of obvious variances in white matter (WM) integrity and glymphatic function between SFS and epilepsy remain unclear. Therefore, this study aimed to investigate the differences in WM integrity...
Periventricular white matter injury (PWMI) is a common cause of spastic cerebral palsy (SCP). Diffusion tensor imaging (DTI) shows high sensitivity but moderate specificity for predicting SCP. The limited specificity may be due to the diverse and extensive brain injuries seen in infants with PWMI. We enrolled 72 infants with corrected age from 6 to...
Background and Aim: Epilepsy is currently considered a common neurological disease associated with excessive neuronal damage. Recent functional MRI studies indicate that frontal cortex activity occurs before thalamic involvement in epileptic discharges, implying that the frontal cortex may play a role in childhood seizures. Therefore, this study ai...
Objective: Brain imaging is important in diagnosing children with cerebral palsy (CP) and in identifying its etiology. To provide study navigation in this field, a bibliometric analysis was conducted by analyzing the most highly cited articles.
Methods: The Web of Science All Databases were used for literature search in this study. All original art...
Background:
Skull stripping remains a challenge for neonatal brain MR image analysis. However, little is known about the accuracy of how skull stripping affects the neonatal brain tissue segmentation and subsequent network construction. This paper therefore aimed to clarify this issue by comparing two automatic (FMRIB Software Library's Brain Extr...
Purpose
The Cerebral glymphatic system, particularly the Virchow–Robin Spaces (VRS), plays an important role in waste clearance from the brain. Idiopathic generalized epilepsy (IGE) is a common epilepsy type associated with blood-brain-barrier dysfunction, abnormal exchange of cerebrospinal fluid and interstitial fluid. These disorders may be refle...
Background: Skull stripping remains a challenge for neonatal brain MR image analysis. However, little is known about how accuracy of the skull stripping affects the neonatal brain tissue segmentation and subsequent network construction. This paper therefore aimed to clarify this issue by comparing two automatic (FSL’s Brain Extraction Tool, BET; In...
Background: Skull stripping remains a challenge for neonatal brain MR image analysis. However, little is known about how accuracy of the skull stripping affects the neonatal brain tissue segmentation and subsequent network construction. This paper therefore aimed to clarify this issue by comparing two automatic (FMRIB Software Library's Brain Extra...
Background: Skull stripping remains a challenge for neonatal brain MR image analysis. However, little is known about how accuracy of the skull stripping affects the neonatal brain tissue segmentation and subsequent network construction. This paper therefore aimed to clarify this issue by comparing two automatic (FMRIB Software Library's Brain Extra...
Background:
Site-specific variations are challenges for pooling analyses in multi-center studies. This work aims to propose an inter-site harmonization method based on dual generative adversarial networks (GANs) for diffusion tensor imaging (DTI) derived metrics on neonatal brains.
Results:
DTI-derived metrics (fractional anisotropy, FA; mean di...
Purpose
Punctate white matter lesions (PWML) are common in preterm neonates and have also been reported in the full term. While most studies focus on white matter abnormalities, gray matter (GM) alterations are generally ignored due to the lack of abnormalities on conventional MRI. This study aims to investigate whether magnetic resonance spectrosc...
Accurate segmentation of punctate white matter lesions (PWML) in preterm neonates by an automatic algorithm can better assist doctors in diagnosis. However, the existing algorithms have many limitations, such as low detection accuracy and large resource consumption. In this paper, a novel spatiotemporal transformation deep learning method called Tr...
Bilateral cerebral palsy (BCP) is a common movement disorder in children, which often results in lifelong motor disability. One main symptom of BCP is the limitation of hand function in everyday activities. However, the neuroanatomical basis of this prominent hand impairment is yet to discover. Recent advances mainly focus on the lesions of BCP, bu...
Accurate segmentation of punctate white matter lesion (PWML) in infantile brains by an automatic algorithm can reduce the potential risk of postnatal development. How to segment PWML effectively has become one of the active topics in medical image segmentation in recent years. In this paper, we construct an efficient two-stage PWML semantic segment...
Background:
Cerebral palsy (CP) is a major cause of chronic childhood disability worldwide, causing activity limitation as well as impairments in sensation, cognition, and communication. Leveraging biomarkers to establish individualized predictions of future treatment responses will be of great value. We aim to develop and validate a model that ca...
Accurate segmentation of punctate white matter lesion (PWML) in infantile brains by an automatic algorithm can reduce the potential risk of postnatal development. How to segment PWML effectively has become one of the active topics in medical image segmentation in recent years. In this paper, we construct an efficient two-stage PWML semantic segment...
Newborn assessments, including gestational age (GA) and anthropometric measurements (birth weight, crown‐heel length, head circumference) are routinely performed in pediatric settings, being used as important indicators in assessing neonatal development. Close associations of these birth indicators with later cognitive abilities were also reported....
Background and Purpose: Periventricular pseudocysts (PVPCs)are cystic cavities originating from the germinal matrix. The effects of PVPCs on the development of white matter (WM)in neonates remain unclear. This study aimed to characterise WM microstructural variations in neonates with PVPCs with and without additional abnormities on MRI. Materials a...
Introduction
Punctate white matter lesions (PWML) are prevalent white matter disease in preterm neonates, and may cause motor disorders and even cerebral palsy. However, precise individual-based diagnosis of lesions that result in an adverse motor outcome remains unclear, and an effective method is urgently needed to guide clinical diagnosis and tr...
Background and purpose:
Periventricular white matter injury is the common cause of spastic cerebral palsy. However, the early diagnosis of spastic cerebral palsy still remains a challenge. Our aim was to investigate whether infants with periventricular white matter injury with bilateral spastic cerebral palsy have unique lesions different from tho...
Purpose
This study aims to provide a screening scoring method by assessing the age-related change of subcortical white matter (WM) myelination via T2-weighted imaging (T2WI).
Methods
This study retrospectively recruited 109 children aged 6–48 months without abnormalities on MRI. Based on Parazzini’s study, we developed a modified T2WI-based method...
Objective
We aimed to determine the timing for assessing birth status of the developing brain (i.e. brain maturity at birth) by exploring the postnatal age-related changes in neonatal brain white matter (WM).
Methods
The institutional review board approved this study and all informed parental consents were obtained. 133 neonates (gestational age,...
Background and purpose:
FOV optimized and constrained undistorted single-shot imaging provides relatively high-resolution images with few artifacts. This study evaluated the image quality and value of FOV optimized and constrained undistorted single-shot DWI in the evaluation of normal pituitary glands and pituitary macroadenomas.
Materials and m...
Purpose To determine whether a single 51-minute exposure to acoustic noise during 3-T multisequence magnetic resonance (MR) neuroimaging could affect the hearing threshold of healthy adults with earplugs and sponge mats as hearing protection. Materials and Methods With earplugs and motion-refraining sponge mats as hearing protection, 26 healthy you...
Adrenal cystic lymphangiomas (ACLs) are rare and benign vascular tumors that are likely to imitate other adrenal cystic lesions on computed tomography (CT) images. We performed a retrospective analysis of the CT appearance and clinical data of all adrenal masses diagnosed by pathological tests at our institute and conducted a systematic review of a...
Background and purpose:
Punctate white matter lesions are common in preterm neonates. Neurodevelopmental outcomes of the neonates are related to the degree of extension. This study aimed to characterize the extent of microstructural variations for different punctate white matter lesion grades.
Materials and methods:
Preterm neonates with punctat...
Purpose:
The relatively poor image contrast and variation in the neonatal brain size are technical challenges associated with the typical tract-based spatial statistics (TBSS) for the target identification and normalization. This study aimed to develop a rapid and reliable pipeline for the neonatal TBSS.
Materials and methods:
A rapid TBSS strat...