Mfonobong AlozieUniversity of Uyo | UNIUYO · department of pharmaceutical microbiology and biotechnology
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Citations since 2016
10 Research Items
This study investigated the ameliorative effects of Vernonia amygdalina and Moringa oleifera on cogni-tive impairment in alloxan-induced diabetes mellitus in male Wistar rats. The animals were allotted into eight groups of five. Group 1 were not induced nor treated. Diabetes was induced with alloxan (135 mg/kg body weight) in groups 2-8. Group 2 wh...
Background Bacteremia constitutes a significant public health challenge and represents a vital cause of morbidity and mortality in HIV-infected patients, and fluoroquinolones are commonly prescribed antibiotics due to their range of activities and pharmacokinetic profiles. This study the evaluated antibacterial activities and time-kill kinetics of...
This work was aimed to assess the antidiabetic effect of orally administered Prosochit®-based nanoparticles of insulin in an animal model. Five batches of insulin-loaded nanoparticles were prepared as dry water-in-oil-in-water emulsions using different emulsifiers (prosopis gum, Prosochit® 201, Prosochit® 101, Prosochit® 102, and chitosan) for the...
Diarrhoea is a leading killer of young children accounting for approximately 8% of all deaths among children ˂ 5 years worldwide and causes neonatal mortality and hospitalization in geriatrics. Ipomoea triloba L. has been claimed to have antidiarrheal properties. This study evaluated antibacterial properties of the ethanol / aqueous extracts and fr...
Background: Cola millenii K. Schum. is a member of Cola which is lesser-known in the family Malvaceae. The leaf is used in the treatment of ringworm, scabies, gonorrhoea, diarrhoea, cough and ophthalmia by the locals. Aim: The study determines various taxonomic, pharmacognostic and phytochemical standards helpful to ensure the identity, purity, saf...
Background: The emergence of multi-drug resistant bacterial strains worldwide has necessitated the scientific search for novel, potent, and affordable antimicrobial agents including medicinal plants and non-antibiotic drugs for therapy of infectious diseases. The objective of this study is to assess in vitro antibacterial activities and time kill k...
As societal needs change, so are professions adjusting and adapting their services to meet this new normal. The essence is not just to remain relevant, but to live up to their professional expectation and be impactful to their environment. In the constantly changing societal healthcare needs, Pharmacists as medicine experts and frontline contributo...
Background and Objectives: Angina pectoris,a pain from the heart felt in the pectoral regions of the upper chest, is a predominant symptom of ischemic heart disease caused by transient episodes of myocardial ischemia. The traditional medications for the treatment were discovered about 60 years ago. The current presentations and complications associ...
Much interest has been indicated in non-invasive drug delivery strategies that achieve fast onset of drug action, prevent its rapid degradation but enhance targeted release. In recent times, the oral film technology has received much attention in line with this because of its versatility, availability for incorporation of numerous drugs as well as...
TO comparatively evaluate the presence or absence of microbial contamination in solid dosage forms particularly tablets. more so, to assess the level of microbial contamination of portable water obtained from boreholes which are source of drinking water in low-and middle-income countries