Merve Yaldız

Mustafa Kemal University · Department of English Language Teaching

To evaluate the effects of memantine on infarct size in cerebral ischemia and on neurological outcome after temporary middle cerebral artery occlusion (MCAO) and reperfusion in rats. In this study, performed between 2002-2004 in Dicle University School of Medicine, Diyarbakir, Turkey, 30 adult Sprague-Dawley rats were used. Cerebral ischemia was co...

The purpose of this study was to investigate methods of removing pathogenic micro-organisms from bone grafts that have been contaminated during surgery. Femora were removed from Sprague-Dawley rats and were divided into sections and contaminated in solutions of the bacteria Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Contam...

Majority of severe disabilities in adults are caused by stroke. The aim of our study is to learn the effects of erythropoietin (EPO), on infarct size in cerebral ischemia and to determine neurological behavioral scores and histopathological evaluation. In this study 30 adult Sprague-Dawney rats were used. Cerebral ischemia was constituted by intral...

Pulmonary angiosarcomas are usually secondary tumors, and only a few primary cases have been reported. We report a unique case of epithelioid angiosarcoma presenting as a solitary mass in the right upper lobe with pulmonary hemorrhage. Because of its epithelioid histology, this tumor may resemble a carcinoma or a variety of vascular lesions with ep...

The aim of this study is to evaluate the efficiency of low-dose, low-molecular-weight heparin (enoxaparin) in the treatment of lichen planus (LP). Twenty-four patients clinically and histopathologically diagnosed as LP with intense pruritus were treated with 3 mg of enoxaparin (Clexane®), subcutaneously once a week for 4–14 weeks. Complete remissio...

Angiomyolipoma (AML) is a benign neoplasm consisting of varying mixtures of smooth muscle, blood vessels and fat. Although, most of these tumors are easy to recognize, some may pose a diagnostic dilemma due to unusual histologic features. Recently, it was suggested that melanosome-associated protein (HMB-45) immunoreactivity may be used for diagnos...

Hydatid disease is an important medical problem in countries of the temperate zones. A 21-year-old female patient was admitted to our outpatient clinics with a complaint of a progressive swelling in the left preauricular region. The case of the patient with hydatid disease that developed in the left preauricular region is presented in detail. Hydat...

The aim of the study was to evaluate the p53 tumor suppressor gene, c-erbB-2 and steroid hormone receptor expression in breast carcinoma by immunohistochemistry and to correlate them with different histopathologic parameters. p53, c-erbB-2, steroid hormone receptors and their correlation with age, tumor size, histological grade, axillary lymph-node...

The aim of this study was to determine the effects of whole blood, crystalloid, and colloid treatment on histopathologic damage of kidney induced by hemorrhagic shock in rats. Fifty-six male Sprague Dawley rats were divided into 8 groups. The carotid artery was cannulated, and systolic arterial pressure (SAP), diastolic arterial pressure (DAP), hea...

Paranasal sinus osteoma is a slow-growing, benign, encapsulated bony tumour that may be commonly asymptomatic, being detected incidentally in 1% of plain sinus radiographs or in 3% sinus computerized tomographic scans. In a patient presenting with epiphora and nasal obstruction, computed tomography disclosed a giant osteoma of the ethmoid. In this...

Primary squamous cell carcinoma of the stomach is extremely rare. To date, only 80 cases have been reported. A 65-year-old man with complaints of epigastric pain and cachexia for the past year is presented. He had a tumour with infiltration of the corpus and antrum of the stomach. The tumour was unresectable, and the patient died within 3 months.

Our purpose was to investigate whether Helicobacter pylori (Hp) has a specific mucosal appearance. Eighty-eight (female / male: 53/35) patients included in the study underwent endoscopy to determine the macroscopic appearance of their gastric mucosa. Biopsies taken from the antrum, incisura angularis and corpus of each patient were stained with tol...

In this study we investigated the histopathological changes of nasal mucosa after the use of topical benzalkonium-chloride solution. In the study, 28 male New Zealand white rabbits were used. The animals were divided into two groups. In the first group, 50 micro l of 0.001% benzalkonium-chloride solution was sprayed into the right nostril and 50 mi...

Cervical biopsy specimens were taken from 16 women with external genital warts in order to diagnose concomitant cervical human papillomavirus (HPV) infection and cervical intraepithelial neoplasia (CIN) according to pathology. Positive HPV infection was detected 56% (9/16) of the patients. Among those patients 66% (6/9) had concurrent subclinical l...

Purpose: Cisplatin (CCDP), an indispensable agent of several chemotherapy protocols, has serious dose limiting side effects, including nephrotoxicity. In this experimental study, we used deferoxamine mesilate (DFO), an iron chelating agent, to ameliorate cisplatin-induced nephrotoxicity. Materials and methods: Sixty adult male bulb-c mice were d...

Ovarian mucinous tumors stem from ovarian surface epithelium and are divided into benign, borderline and malignant. It is difficult to differentiate borderline and malignant mucinous tumors. Thirty-eight cases of ovarian mucinous tumors which were diagnosed at the Pathology Department of Dicle University Medical Faculty were reviewed. Of these, 18...

We conducted a clinical and pathologic review of nine patients with immature ovarian teratoma. The histologic grade of the tumor seemed to be a reliable indicator of prognosis. Low stage and low grade immature ovarian teratomas have an excellent prognosis. Platinum-based chemotherapy has been confirmed to be effective in the management of patients...

Castleman's disease (giant lymph node hyperplasia) is an uncommon cause of neck mass. Its cause and pathogenesis are still unknown. Giant lymph node hyperplasia (GLH) usually presents as an asymptomatic solitary mass and can occur anywhere in the head and neck. Diagnostic test results are always inconclusive. Excision and histopathological evaluati...

Nevoid hyperkeratosis of the nipple and areola is a rare benign condition of unknown etiology, Its characteristic properties are verrucous thickening and brownish discoloration of the nipple and areola. In microscopic examination, hyperkeratosis, papillomatosis and acanthosis with keratotic plugging were observed and nevoid hyperkeratosis was diagn...

We report the CT, ultrasonographic, and pathologic features of a localized forms of Castleman's disease in the porta hepatis due to their unusual location. Our report suggests that the CT and the ultrasonographic features of Castleman's disease in these locations without calcifications is nonspecific.

The dithiocarbamates are known to cause dermatitis, conjunctivitis, rhinitis, pharyngitis and bronchitis in humans. The experimental group received Propineb (obtained from Bayer) concentrations of 400 ppm in distilled water five days a week (treatment time three weeks) administered orally by gasric pit. Acute oral LD50 for male rats has been found...

A 57-year-old man presented with progressively increasing shortness of breath. A chest roentgenogram showed the presence of a giant mass and magnetic resonance of the chest confirmed the mass with an inhomogeneous density in the right hemithorax. The patient underwent a thoracotomy. A tumor was seen to have arisen from the parietal pleura. Size of...

The pathology of mucocele was reviewed and two appendiceal mucoceles were evaluated. These were diagnosed at the Pathology Department of Dicle University between 1990 and 1999. The changes in the lining epithelium of the mucocele were emphasized.

Leiomyoma is quite rare in the female urethra. We report an additional case to 29 reported in the literature. A multiparous woman presented with a complaint of a gradually enlarging mass causing dyspareunia for the last seven months. The mass was originating from the upper part of the distal urethra with a relatively thin stalk covered by squamous...

Unlabelled: Ten male Wistar-albino rats were overfed with high-fat diet (margarine at the dose 40 g/kg body weight/day in addition to standard rat diet) during six months from the age of between 8-12 weeks. Ten male rats received a standard chow for the same period. The body weights of the overfed rats increased time dependently (basal 171.5 +/- 5...

Purpose: In this study it was aimed to analyse the non-Hodgkin lymphomas of Southeastern Turkey retrospectively. Material and methods: Between the years 1984 and 1995, 185 patients with non-Hodgkin lymphoma were retrospectively reviewed in The Pathology Department of Dicle University Medical School. All of the cases were classified according to the...

In this study, cadmium chloride injection (I.V.) was administered to 17- 21 day pregnant Wistar Albino rats. The weight and liver histology of rats were then investigated. This short time administration of cadmium caused decrease in body weight and degeneration of liver structure in pregnant rats.

SUMMARY DIAGNOSTIC VALUE OF PLEURAL FLUID CYTOLOGIC EVALUATION AND BIOPSY In this study, the value of pleural thoracenteses and biopsy is discussed in 161 patients having pleural fluid. The mean age was 54.57. Of all cases, 54 were malignant pleurisy, and 107 were benign pleurisy. Of the 54 cases with malignant pleurisy, 35 were malignant mesotheli...

Congenital granular cell epulis of the newborn is a rare lesion whose histogenesis and natural clinical history have remained obscure. It is important that new cases of this lesion are reported from different populations so that its occurrence and frequency may be ascertained more accurately. Furthermore, the lesion is important in the differential...