Mervat Alsous

Mervat Alsous
Yarmouk University | YU · Pharmacy Practice

Dean of faculty of Pharmacy /Yarmouk University/Associate Professor in Clinical Pharmacy/ Pharmacokinetics

About

51
Publications
10,620
Reads
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393
Citations
Citations since 2016
46 Research Items
393 Citations
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2016201720182019202020212022020406080100120
Introduction
-Interested in Clinical Pharmacy and pharmacy practice research and pharmacokinetics, working in collaboration with many academics from Jordan and researchers from the school of pharmacy/ Queen's University Belfast and University College London. -Research interests include: Adherence to medications in children with leukemia, inflammatory bowel disease and epilepsy using subjective and objective methods. Pharmacovigilance. Antibiotic use in Jordan. Beliefs about medications and depression as factors affecting adherence to medications. Analysis of drugs in plasma and dried blood samples using HPLC and Mass-spectrometry. Pharmacokinetics of ketamine in neonates.

Publications

Publications (51)
Article
The Covid‐19 pandemic has changed almost all aspects of education. The anatomy and histology courses for pharmacy students focus heavily on the face‐to‐face communication of theory and practical knowledge and due to the pandemic, only theory content was delivered in an online format. This brought up many concerns about pharmacy student preparedness...
Article
Full-text available
Data archives of clinical microbiology laboratory (CML) are a rich source of valuable information. In this study, CML data from two tertiary care hospitals in Jordan were reviewed, in order to identify the source prevalence of microorganisms and the dissemination of Extended Spectrum Beta-Lactamase (ESBL) bacteria. The association between gender an...
Article
Full-text available
Objectives To assess the knowledge about cervical cancer and HPV infection and the awareness towards and perceived barriers of HPV vaccination amid medical students in Jordan. Methods The present study is a cross-sectional survey that was conducted for a period of three months in the College of Medicine at six different universities in Jordan. Thi...
Article
Full-text available
Self-medication can facilitate patients' access to medicinal products, save time, and reduce financial and health-care service use burden. On the other hand, irresponsible use of self-medications can result in adverse consequences. Self-medication is common among different demographic groups including pregnant women. In general, medicinal products...
Article
Background Digoxin is a cardiac glycoside that was introduced to cardiovascular medicine more than 200 years ago. Its use is associated with large variability, which complicates achieving the desired therapeutic outcomes.Objectives To present a synthesis of the available literature on the population pharmacokinetics of digoxin in adults and to iden...
Article
Full-text available
Cervical cancer (CC) is one of the most common types of cancer that affect females worldwide with hundreds of thousands of women dying annually due to this disease, mainly in developing countries. Infection with human papillomavirus (HPV) is the main risk factor for this cancer. There are no public awareness and national immunization programs in mo...
Preprint
Full-text available
Background Cervical cancer (CC) is the most common gynecologic malignancy worldwide and the fourth most common cancer in women. Most cases of cervical cancer are attributed to Human Papillomavirus (HPV). Assessment of knowledge about cervical cancer and HPV vaccination is needed. Results 504 students took part in the study. 42.3% of males and 57.7%...
Article
Full-text available
Background: Outbreaks and containment measures implemented to control them can increase stress in affected populations. The impact of the COVID-19 outbreak on perceived stress levels in the Jordanian population is unknown. Aims: To determine the perceived stress level and factors associated with it in the Jordanian population during the COVID-19...
Article
Background: Awareness of pharmacovigilance among pharmacy academics increases the students and graduated pharmacists' knowledge and skills in reporting adverse drug reactions (ADRs). Purpose: The aims of this study are to assess the level of awareness about pharmacovigilance among pharmacy school academics in Jordan and to explore the current pharm...
Article
Background Knowledge of medication use during pregnancy presents a concern to pharmacists upon graduation since they will be responsible for drug related inquiries and counselling pregnant women about their medications. The present study aimed to assess undergraduate senior pharmacy students’ knowledge about medication use during pregnancy in Jorda...
Article
Full-text available
Background The novel 2019 coronavirus outbreak that first appeared in Wuhan has quickly gained global attention, due to its high transmissibility and devastating clinical and economic outcomes. Aims to assess the possible roles of Jordanian pharmacists in minimizing the stage of community transmission. Methods A cross-sectional survey using Googl...
Article
Aim To assess the impact of educational workshops on the knowledge, attitudes, and intended practices (KAP) of the general public towards diabetes in Jordan in terms of symptoms, risk factors, complications, and prevention. Methods A pharmacist led educational intervention and Propensity score matching was carried out for a convenience sample to a...
Article
This is a PROSPERO registered systematic review (CRD42018105207), conducted to summarize the available knowledge regarding the population pharmacokinetics of digoxin in pediatrics and to identify the sources of variability in its disposition. PubMed, ISI Web of Science, SCOPUS and Science Direct databases were searched from inception to January‐201...
Article
Full-text available
Background. Measurement of the degree of adherence is a key element for the evaluation of treatment efficacy and safety; thus, adherence plays an important role in clinical research and practice. The aim of this study was to investigate medication adherence in children with inflammatory bowel disease (IBD) utilizing a multimethod assessment approac...
Article
The use of the dried blood spot (DBS) sampling technique has extended the scope of clinical research particularly in children. The effect of different HCT levels (25‐55%) and different blood volumes (7.5‐30 μl) on the surface area of the blood spots were investigated using ImageJ® software. Variation in HCT levels between patients and inaccuracies...
Article
Full-text available
Due to the shortage of literature related to the safe use of over‐the‐counter (OTC) products by patients worldwide, the aim of this study was to evaluate people's knowledge and attitudes regarding the use of OTC products in Jordan. Using an internet‐based questionnaire mainly spread through social media platforms, a descriptive cross‐sectional stud...
Article
Background: The use of complementary and alternative medicine in infants to maintain health and treat illnesses is popular in Jordan. No guidelines or regulations govern their use. Aims: This study explored mothers' knowledge and use of complementary and alternative therapies for infants younger than 3 months in Jordan and their reasons for usin...
Article
The analysis of 6-thioguanine (6-TG) and 6-methylmercaptopurine (6-mMP) in biological samples is not straight forward and requires pre-treatment of samples. There are no validated published methods for the analysis of azathioprine/6-mercaptopurine (AZA/6-MP) metabolites in dried blood spot (DBS) samples that study the correlation with red blood cel...
Article
Full-text available
It is well known that the emergence of antibiotic resistance is linked to the misuse and over-use of antibiotics. Misuse includes self-medication and the inappropriate use of antibiotics because of improper dosage or improper duration than recommended. This study investigated three patterns of dispensing antibiotics in a sample of community pharmac...
Data
All relevant raw data collected from the dispensers and customers/patients. (XLSX)
Data
Data collection form from dispensers. (DOCX)
Data
Data collection form from customers/patients. (DOCX)
Article
Full-text available
Aims To assess the knowledge and practices toward diabetes in the Jordanian community. Methods This study was conducted as a public based cross-sectional study in different cities in Jordan. A previously published validated questionnaire about knowledge, attitudes, and practices (KAP) toward diabetes mellitus (DM) was translated from the Arabic ve...
Data
English translated questionnaire. (DOCX)
Article
Aims: The aim of the present study was, to use a multiple methods approach, including, for the first time, dried blood spot (DBS) sampling with PopPK interpretation, to assess adherence to mycophenolate in children with kidney transplant. A second aim was to identify patient/parental factors that influenced adherence and to link adherence behaviou...
Article
Full-text available
Aim: The aim of this study was to assess levels of depressive symptoms present in patients with diabetic foot. Methods: A convenience sampling method was used to recruit 108 patients with diabetic foot. After having completed the Centre for Epidemiologic Studies Depression Scale CES-D scale, the patients' demographic data and medical history were c...
Article
Background: There is a lack of a standardized tool for adherence measurement in patients with epilepsy. Studies in children with epilepsy have reported adherence in 50-96.5%. The primary objective of this study was to identify predictors of nonadherence to antiepileptic drugs (AEDs) using two different methods in Jordanian children and adolescents...
Article
Full-text available
Problem: To assess the practice of self-medication, among pharmacy students. Experimental approach: A cross-sectional study was conducted for a period of three months. A pre-validated questionnaire was distributed to pharmacy students at the University of Jordan. A total of 256 students participated in the study. Major Findings: The prevalence of s...
Article
Introduction Viral infection is the main cause of Upper respiratory tract infections (URTIs). However, antibiotic resistance is promoted through inappropriate prescription of antibiotics for children with URTIs. This study aimed to assess the possible risk factors which may be associated with such antibiotic misuse. Methods This prospective study w...
Article
Full-text available
Abstract Background and Aims: It has been demonstrated that homozygote and heterozygote mutant allele carriers for thiopurine S-methyltransferase (TPMT) are at high risk of developing myelosuppression after receiving standard doses of 6-mercaptopurine (6-MP). The aim of this study was to determine the frequency of TPMT deficient alleles in childre...
Article
Full-text available
Surgical site infections (SSIs) following caesarean surgeries are common. The present study aimed to evaluate the frequency of SSIs following caesareans at Jordan University Hospital during the 30 postoperative days and to identify factors associated with increased SSIs risk. Data regarding the occurrence of SSIs were collected both prospectively v...
Article
Full-text available
Objective Studies on children with Acute Lymphoblastic Leukemia (ALL) reported non-adherence in 2–54% of cases. The primary objective of this study was to assess rates of adherence to 6-MP using two different methods in children and adolescents with ALL. Secondary aim was to identify factors that influence adherence to 6-MP in children with ALL. M...
Data
Development and validation of an HPLC method for the determination of 6-MP in packed red blood cells and plasma. (PDF)
Article
Full-text available
Background: Pharmaceutical companies provide a broad range of different mandatory trainings to their medical representatives to keep the business running, however research related training has often been neglected by these companies. Thus, this study was developed to assess the amount of scientific research knowledge and interest among pharmacy me...
Article
Full-text available
Levetiracetam (LVT) is a widely used antiepileptic drug (AED). A less invasive sampling method for therapeutic drug monitoring (TDM) would be very useful particularly for children. Saliva has been shown as an adequate sample for TDM of some AEDs. Due to the high hydrophilicity of LVT its separation on common stationary phases is quite a challenge s...
Article
BACKGROUND: Surgical site infections are common, especially in developing countries. Nevertheless, up to 60% of surgical site infections can be prevented with appropriate perioperative care, which includes among other measures using suitable surgical antimicrobial prophylaxis (SAP). METHODS: After a short interview with patients and retrospective...
Article
Full-text available
Background: Surgical site infections (SSIs) are common, especially in developing countries. Nevertheless, up to 60% of SSIs can be prevented with appropriate perioperative care, which includes among other measures using suitable surgical antimicrobial prophylaxis (SAP). Methods: After a short interview with patients and retrospective review of med...
Article
Abstract: Background: Surgical site infections (SSIs) are common, especially in developing countries. Nevertheless, up to 60% of SSIs can be prevented with appropriate perioperative care, which includes among other measures using suitable surgical antimicrobial prophylaxis (SAP). Methods: After a short interview with patients and retrospective rev...
Article
Full-text available
Objectives to evaluate the reliability and discriminant validity of Arabic translation of the Medication Adherence Report Scale (MARS) and the Beliefs about Medication Questionnaire-specific (BMQ-specific). Methods Having developed Arabic translations of the study instruments, a cross-sectional study was carried out between March and October 2015...
Article
Full-text available
Most of clinical research studies are focused on the adult population with relatively few studies carried out in children due to ethical issues and the practical difficulties in conducting research studies in this patient group [1]. Safe use of medicine is, however, an important issue especially in children, due to inappropriate dosing regimens tha...
Conference Paper
Full-text available
Objectives: The aims of this study were to assess depressive symptoms in patients with diabetic foot using center for epidemiologic studies depression scale (CES-D) and investigate the association between depressive symptoms and characteristics of patients with diabetic foot. Methods: A sample of 108 patients with diabetic foot was recruited from M...
Article
Full-text available
Purpose: To assess the knowledge, attitudes and practices of parents towards antibiotics use for upper respiratory tract infections (URTIs) in Jordan. Methods: A cross-sectional study was carried out at 10 private outpatients’ pediatric clinics across Amman-Jordan from September to December 2013. During the study period, 1329 parents of young chil...
Conference Paper
Full-text available
Use of medicine is usually associated with harm that may range from mild to fatal adverse drug reactions (ADRs). Pharmacists as health care professionals working in a hospital or community pharmacy can play an essential role in both pharmacovigilance activities and ADRs reporting. This study has been conducted to assess perceptions and knowledge of...
Article
Full-text available
Purpose: To assess the perceptions and knowledge of pharmacovigilance and adverse drug reactions (ADRs) reporting among Bachelor of Pharmacy (BPharm) and Doctor of Pharmacy (PharmD) students of selected tertiary institutions in Jordan. Methods: A cross-sectional study, involving 434 pharmacy students from three different Jordanian universities, was...
Thesis
Full-text available
Abstract Safe and effective use of medicines is an important issue especially in children with chronic illness who are less resilient to adverse events and in whom disease progression may not be addressed if appropriate medication is not taken. The research programme presented in this thesis focused on the use of dried blood spot (DBS) sampling in...
Thesis
Full-text available
THE IMPACT OF PATIENTS’ EDUCATION ABOUT WARFARIN ON IMPROVEMENT OF THEIR BASAL KNOWLEDGE REGARDING ITS ADMINISTRATION AND SIDE EFFECTS: A STUDY ON PATIENTS WHO RECEIVE WARFARIN AT JORDAN UNIVERSITY HOSPITAL By Mervat Musbah Zaki Al-Sous Supervisor Dr. Nailya Bulatova ABSTRACT Research problem Patients’ knowledge about warfarin was reported to...

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Projects

Projects (8)
Project
To assess KAP about DM among general public in Jordan
Project
To assess the prevalence and trends of self medication among students and public in Jordan