Melis Kizilkan

Hacettepe University · Department of Pediatrics, Division of Adolescent Medicine

Introduction: Pubertal gynecomastia is a common clinical condition among male adolescents and in most cases it regresses spontaneously. However, tamoxifen treatment is recommended in selected cases. We aimed to evaluate the indications, safety and efficacy of tamoxifen treatment in adolescents with pubertal gynecomastia. Methods: The data of 83 ado...

Aim: The aim of this study was to identify the prevalence of undetected eating disorders (EDs) among adolescent psychiatric inpatients and to investigate the association between clinical, psychiatric, and sociocultural factors and EDs. Methods: Between January and December 2018, patients aged 12-18 years, hospitalized for inpatient-level treatme...

Objectives: Understanding the factors causing nonurgent visits to the pediatric emergency departments (PED) is essential for developing effective interventions. Sociodemographic factors might have a direct effect, or they might be associated with other potential causal factors such as access, perceived severity, and convenience. Therefore, we aime...

Background: Pregabalin is an inhibitor of gamma-aminobutyric acid (GABA) and can be abused, especially by polydrug abuser adults. Drug abuse is one of the many risky behaviors that can be seen during adolescence. Here, three adolescents with pregabalin abuse were described. Case: These adolescents abused pregabalin to cope with their depressive...

Objectives Androgen receptor gene CAG repeat, AR (CAG) n , polymorphism is thought to have an effect on male reproductive functions and a relationship between long AR (CAG) n and decreased androgenic activity has been shown. Therefore, we hypothesized that in adolescents with long AR CAG repeat the prevalence of pubertal gynecomastia (PG) will be h...

Introduction: Primary Immunodeficiency diseases(PID) are common in patients with non-cystic

Background The nail fold video capillaroscopy (NVC) is usually performed on patients with microcirculation problems, such as Raynaud’s phenomenon. It is also used to distinguish between primary and secondary Raynaud’s Phenomenon and identify the scleroderma pattern. Objectives To describe the acute phase nail fold capillaroscopic findings of adole...

The purpose of this case series was to evaluate menstrual suppression in sex assigned at birth female adolescents identifying as male or gender non-conforming. A retrospective chart review of 4 gender minority youth (GMY), age 14-17, was performed for gender identity history, type and success of menstrual suppression, method satisfaction, side effe...

Study objective: This study aimed to evaluate the presence of anovulation in adolescents with Primary Dysmenorrhea (PD). Design: Prospective cohort study SETTING: Hacettepe University Children's Hospital, Adolescent Medicine outpatient clinic between September 2018 and September 2019 PARTICIPANTS: Healthy female adolescents (between 11-18 years...

IntroductionWe aimed to evaluate the bone mineral density (BMD) z scores of adolescents with atypical anorexia nervosa (AAN) and investigate the potential predictors of low BMD risk.Materials and methodsPotential factors that might have an effect on the femoral neck and lumbar spine dual energy X-ray absorptiometry data of adolescents (11–18 years)...

This study evaluated the nutritional status of Syrian refugees in the early adolescent period living in different vulnerable settings. Nutritional assessment of Syrian refugee adolescents is often neglected but essential for a healthy physical, pubertal and mental development. Growth parameters of Syrian refugee adolescents going to a public school...

Zinc has shown to have an anti-androgenic effect through 5 alpha-reductase enzyme activity inhibition in skin. However, there are contradicting findings concerning the effect of zinc on hirsutism mainly from studies including adult women with polycystic ovary syndrome (PCOS). The aim of our study was to investigate the association between serum zin...

Background Adolescents with eating disorders (EDs) may present not only with abnormal eating behaviors but also with abnormal drinking behaviors varying widely. These behaviors include water loading to cheat on weight measurements, to feel full and suppress appetite and/or to induce vomiting; as well as restricting fluid intake in addition to food....

Introduction.Primary Immunodeficiency diseases(PID) are common in patients with non-cystic fibrosis bronchiectasis(NCFB). Our objective was to determine ratio/types of PID in NCFB. Patients.Seventy NCFB patients followed up in a two-year period were enrolled. Results.Median age was 14 years (min.-max., 6-30). Patients had their first pulmonary infe...

Endocrine disruptors have been proposed in the etiology of polycystic ovary syndrome (PCOS) as they have the potency to interfere with hormone-sensitivity systems. The aim of this study was to evaluate the levels of bisphenol A (BPA) and phtalates in adolescents with PCOS. Sixty-two girls with PCOS and 33 controls, age 12–18 years were enrolled in...

Background The negative impact of anorexia nervosa (AN) on bone health is well defined. However, there are very few studies evaluating the effect of constitutional thinness on bone health, especially in the adolescent period and in the male gender. The aim of this study is to compare the bone mineral density (BMD) measurements of adolescents with A...

Background and aims The refeeding syndrome (RFS) is a potentially fatal condition characterised by fluid and electrolyte abnormalities, most notably hypophosphatemia. The purpose of this study was to determine the incidence of hypophosphatemia without prophylactic phosphate supplementation during refeeding in hospitalised adolescents with Anorexia...

Background: Since vitamin D has an inhibitory function on ductal morphogenesis of the pubertal mammary gland, it may have a role in the development of gynecomastia. The aim of this study was to determine the effect of vitamin D deficiency on the development of pubertal gynecomastia. Methods: Serum 25-hydroxyvitamin D (25D) levels in 50 adolescen...

Low T3 syndrome is a physiological adaptation seen in anorexia nervosa (AN) and it generally improves with sufficient weight gain. However when a primary thyroid pathology accompanies AN, both the evaluation of thyroid hormone levels and the management of the co- morbid disease become more challenging. Hashimoto thyroiditis could complicate the man...

There are a range of different services for treating adolescent eating disorders (ED) but there is no clinical consensus and a paucity of research indicating which type of treatment setting is the best. Although it would be ideal to have a specialized ward for these patients what happens when this is not possible? The aim of this study was to evalu...