Melanie Swan

DIYgenomics · Research

In the Introduction to Husserl's Origin of Geometry, Derrida ostensibly inquires into the historicity of ideal objects, but the real topic is thinking. Geometry produced a revolution in the mode of thinking for Greek scholars and continues to do so as we are now no longer writing merely the products of thinking in the computational infrastructure b...

Health Agents are introduced as the concept of a personalized AI health advisor overlay for continuous health monitoring (e.g. 1000x/minute) medical-grade smartwatches and wearables for “healthcare by app” instead of “sickcare by appointment.” Individuals can customize the level of detail in the information they view. Health Agents “speak” natural...

A second Linguistic Turn is proposed to study the preponderance of formal language configuring the technological infrastructure, and the implication of this for meaning construal. Such a second movement extends the initial Linguistic Turn's focus on natural language to formal languages such as mathematics, physics, computer code, and genAI LLMs (ge...

Health Agents are introduced as the concept of a personalized AI health advisor overlay for continuous health monitoring (e.g. 1000x/minute) medical-grade smartwatches and wearables for "healthcare by app" instead of "sickcare by appointment." Individuals can customize the level of detail in the information they view. Health Agents "speak" natural...

This work is a Hume-inspired artificial intelligence (AI) theory paper. In the vein of Humean narratives for the next 50 years and interdisciplinary knowledge efforts, there is an urgent need to develop conceptual resources for understanding and maneuvering in a world of fast-paced AI development in science and beyond (Table 1). The Humean lens of...

A Continental philosophy approach illuminates the BioEpisteme as an information science knowledge regime, analyzing implications of the digital encoding and manipulation of biology with critical genealogies of unreason, episteme, and autoimmunity.

A Continental philosophy approach illuminates the BioEpisteme as an information science knowledge regime, analyzing implications of the digital encoding and manipulation of biology with critical genealogies of unreason, episteme, and autoimmunity.

Propose Information Systems Biology as a model of systems biology in which information is a primary organizing principle and biosystems are considered as multiscalar entities of information creation, representation, and transfer. Discuss AdS/Biology and Chern-Simons Biology as models for testing the application of physics findings to biophysics in...

Reason is necessary to complete the operation of the understanding and cognize an empirical object. This suggests an architectonic reach back from the Dialectic to the Analytic (§26 B160n) and the Aesthetic. The three faculties of sensibility, understanding, and reason jointly cognize an object. The problem of time hinders their interoperability (d...

The advancement in generative AI could be boosted with more accessible mathematics. Beyond human-AI chat, large language models (LLMs) are emerging in programming, algorithm discovery, and theorem proving, yet their genomics application is limited. This project introduces Math Agents and mathematical embedding as fresh entries to the "Moore's Law o...

AI Math Agents are introduced as a novel ontological emergence for the creation of the digital mathematical infrastructure, to explicitly extend human intelligence. Mathematics (the elaboration of mathematical structures in the world) is crucial but stuck in non-evaluable formats. Further scientific progress is not possible by advance in computing...

This research examines the practice of cryonics and provides empirical evidence for an improved understanding of the motivations and attitudes of participants. Cryonics is the freezing of a person who has died of a disease in hopes of restoring life at some future time when a cure may be available. So far, about 300 people have been cryopreserved,...

Derrida and Hegel offer distinct viable options for the critical understanding of difference which can be applied to the contemporary context of socio-political philosophies based on the recognition of difference.

Quantum matter (novel phases of matter at zero temperature with exotic properties) is a growing field with applications in its own domain, and in providing foundational support to quantum sciences fields more generally. The ability to characterize and manipulate matter at the smallest scales continues to advance in fundamental ways. This review pro...

Quantum neurobiology is concerned with potential quantum effects operating in the brain and the application of quantum information science to neuroscience problems, the latter of which is the main focus of the current paper. The human brain is fundamentally a multiscalar problem, with complex behavior spanning nine orders of magnitude-scale tiers f...

The day began as any other. Quantum BCI cloudmind facilitators initialized projects for the post-future-of-work productive engagement of the populace, physicists attempted a scheme for putting scalar hair on a black hole, hundreds of new extremal wormhole papers appeared on the arXiv, an asteroid impact was averted with a Dyson sphere space junk re...

Quantum computing is implicated as a next-generation solution to supplement traditional von Neumann architectures in an era of post-Moores law computing. As classical computational infrastructure becomes more limited, quantum platforms offer expandability in terms of scale, energy-consumption, and native three-dimensional problem modeling. Quantum...

Quantum Computing for the Brain argues that the brain is the killer application for quantum computing. No other system is as complex, as multidimensional in time and space, as dynamic, as less well-understood, as of peak interest, and as in need of three-dimensional modeling as it functions in real-life, as the brain. Quantum computing has emerged...

Distributed ledger technology, frequently designated as "blockchain," is evolving from its hype phase toward greater maturity and long-term value creation. Although many academic communities were initially slow to grasp the technology's numerous potential implications, meanwhile a substantial amount of research is dedicated to investigating the dev...

This essay argues that the AdS/CFT correspondence, as a limits-based model of undecidability and non-computability, highlights quantum reality as being not only information-theoretic, but rigorously computational as a mathematically-sound domain with built-in cryptographic security features such that black holes provide their own zero-knowledge pro...

In the concluding part of this book on nanomedical brain/cloud interface (B/CI) technologies, the current chapter considers the greater impact of these advances on humanity. For the general realization of the B/CI and especially for B/CI cloudminds (minds safely connected to the internet cloud via B/CI for interactive purposes), a robust hardware a...

The aim of this book is to formalize research regarding technophysics (the application of physics to the study of technology) and smart networks (intelligent autonomously-operating networks), invited but not restricted to the areas of study proposed in this research agenda. (CAN'T SHARE THE FULL-TEXT. SORRY)

This research examines the practice of cryonics and provides empirical evidence for an improved understanding of the motivations and attitudes of participants. Cryonics is the freezing of a person who has died of a disease in hopes of restoring life at some future time when a cure may be available. So far, about 300 people have been cryopreserved,...

The Internet comprises a decentralized global system that serves humanity’s collective effort to generate, process, and store data, most of which is handled by the rapidly expanding cloud. A stable, secure, real-time system may allow for interfacing the cloud with the human brain. One promising strategy for enabling such a system, denoted here as a...

This practical introduction explains the field of Blockchain Economics, the economic models emerging with the implementation of distributed ledger technology. These models are characterized by three factors: open platform business models, cryptotoken money supplies, and Initial Coin Offerings as a new and official form of financing. The book covers...

This chapter discusses how the widespread adoption of blockchain technology (distributed ledgers) might contribute to solving a larger class of economic problems related to systemic risk, specifically the degree of systemic risk in financial networks (ongoing credit relationships between parties). The chapter introduces economic network theory, dra...

This chapter discusses risk in the context of blockchain technology and proposes a theory of programmable risk that can be implemented with Black Swan Smart Contracts. The theory’s foundations are developed from two perspectives: risk theorizing in philosophy, social science, and finance; and black swan financial theory (risk distributions are fat-...

This practical introduction explains the field of Blockchain Economics, the economic models emerging with the implementation of distributed ledger technology. These models are characterized by three factors: open platform business models, cryptotoken money supplies, and Initial Coin Offerings as a new and official form of financing. The book covers...

This practical introduction explains the field of Blockchain Economics, the economic models emerging with the implementation of distributed ledger technology. These models are characterized by three factors: open platform business models, cryptotoken money supplies, and Initial Coin Offerings as a new and official form of financing. The book covers...

Considering the mutual benefits of blockchain and transhumanism, this essay proposes crypto cloudminds as a safe mechanism by which the human mind might transcend its unitary limitations by permissioning partial resources to join a multi-party mind (comprised of human and machine minds) in a cloud-based environment. Cloudminds could have diverse pu...

The aim of this paper is to propose a theoretical construct, smart network field theory, for the characterization, monitoring, and control of smart network systems. Smart network systems are intelligent autonomously-operating networks, a new form of global computational infrastructure that includes blockchains, deep learning, and autonomous-strike...

This chapter extends the notion of Global Health Care Equivalency (GHCE) with an econophysics-based formulation of quantized fungible GHCE units for health and well-being. A theoretical model of disease causality based on data science is proposed as the first step towards the enactment of GHCE units. New data science concepts are introduced, techno...

This research examines the practice of cryonics and provides empirical evidence for an improved understanding of the motivations and attitudes of participants. Cryonics is the freezing of a person who has died of a disease in hopes of restoring life at some future time when a cure may be available. So far, about 300 people have been cryopreserved,...

Exceeding current cognitive limitations will require both technological advance and progression in mindset as to the notion of personal identity and its confines, for example to contemplate joining a collaborative mind community, since biomedical advance can only deliver so much so fast. Cognitive enhancement is not going to be exclusively a result...

This paper articulates the notion of the cryptocitizen who thinks freely of the traditional dictates of authority. The analysis looks beyond the immediate economic benefits and risks of blockchain technology to consider the broader implications for the individual and society. The possibility of creating and participating in different and multiple s...

The key to developing Ethical Machine Consciousness is creating well-formed structures of reality without the lens of speciesism. Corollary: Use philosophical resources to address challenges of technology and society

This chapter discusses Blockchain distributed ledgers in the context of public and private Blockchains, enterprise Blockchain deployments, and the role of Blockchains in next-generation artificial intelligence systems, notably deep learning Blockchains. Blockchain technology is a software protocol for the secure transfer of unique instances of valu...

Big Data Theory is a set of generalized principles which explain the foundations, knowledge, and methods used in the practice of data-driven science.

In this general overview article intended for non-experts, I define blockchain technology and some of the key concepts, and then I elaborate four specific applications that highlight the potential economic benefits of digital ledgers. These applications are digital asset registries, blockchains as leapfrog technology for global financial inclusion,...

This article introduces the symposium “Toward a Philosophy of Blockchain,” which provides a philosophical contemplation of blockchain technology, the digital ledger software underlying cryptocurrencies such as bitcoin, for the secure transfer of money, assets, and information via the Internet without needing a third-party intermediary. The symposiu...

In our increasingly automated economy, technology has replaced much of the need for non-elective human labor: in others words, we increasingly face a situation of technological unemployment. Thus automation is a double-edged sword. On the one hand, technological unemployment worsens income inequality and wealth disparity. On the other hand, there a...

The aim of this paper is to present conceptual resources that address social robotics from a philosophical, social, and economic perspective. Since social robotics is an emerging and potentially high-impact area, it is necessary to consider the ethics and philosophy of social robotics and its potential impact on society. Philosophical, economic, an...

The aim of this paper is to explore the development of brain-computer interfacing and cloudminds as possible future scenarios. I describe potential applications such as selling unused brain processing cycles and the blockchaining of personality functions. The possibility of ubiquitous brain-computer interfaces (BCIs) that are continuously connected...

The aims of this paper are to (1) provide a conceptual context for smart contracts, (2) argue that blockchains are a next-generation technology enabling much larger-scale and more complex computing projects, and (3) posit blocktime as a new mode of conceiving time. Blockchains are the distributed ledger technology underlying Bitcoin and other crypt...

My aim in this paper is to investigate the conceptual underpinnings of the notion of Bildung in the Elements of the Philosophy of Right (PR) though earlier determinations in Science of Logic (SL). My motivation is to enrichen the reading of both PR and SL, and to obtain additional conceptual resources beyond what Hegel configured directly, in new c...

The purpose of this chapter is to conceptualize cognitive nanorobots, an ethics of perception, and machine ethics interfaces. Three areas are developed as a foundational background. First is the context and definition of cognitive nanorobots (nano-scale machines that could be deployed to facilitate, aid, and improve the processes of cognition like...

Reports on the concept of blockchains, a new form of information technology that could have several important future applications. One is blockchain thinking, formulating thinking as a blockchain process. This could have benefits for both artificial intelligence and human enhancement, and their potential integration. Blockchain thinking is outlined...

The pure image of subjectivation is appropriately doubled like duration-as-time, duration-as-consciousness, duration-as-thinking, and now the internal qualitative sense of duration-as-subjectivation. This is not just a self-aware subjectivation, but a sensibility for subjectivation, possibly by living in virtuality. As pure thought is a sensibility...

The automotive industry could be facing a situation of profound change and opportunity in the coming decades. There are a number of influencing factors such as increasing urban and aging populations, self-driving cars, 3D parts printing, energy innovation, and new models of transportation service delivery (Zipcar, Uber). The connected car means tha...

Simondon's theory of individuation is the dynamic world process by which everything arises: technology, living beings, individuals, groups and thoughts. The full subjectivation of the individual requires both individual and collective individuations. This paper examines how the Contemporary Media Environment (CME) may be influencing the realization...

The purpose of this chapter is to conceptualize cognitive nanorobots, an ethics of perception, and machine ethics interfaces. Three areas are developed as a foundational background. First is the context and definition of cognitive nanorobots (nano-scale machines that could be deployed to facilitate, aid, and improve the processes of cognition like...

Simondon’s theory of individuation is the dynamic world process by which everything arises: technology, living beings, individuals, groups and thoughts. The full subjectivation of the individual requires both individual and collective individuations. This paper examines how the Contemporary Media Environment (CME) may be influencing the realizatio...

Twentieth century philosophers such as Simondon and Heidegger propose theories of subjectivation that inform our thinking about the definition of personhood and how it arises, including in the potentially wide-ranging context of personhood beyond the human. Simondon’s theory of transindividuation unfolds as a series of decenterings that provides a...

Sharing personal health information is essential to create next generation healthcare services. To realize preventive and personalized medicine, large numbers of consumers must pool health information to create datasets that can be analyzed for wellness and disease trends. Incorporating this information will not only empower consumers, but also ena...

We have been testing the hypotheses that our unconscious behaviors are often more predominant than our conscious behaviors. We have tried to quantify the degree of influence of our genetic factors and unconscious signals from the environment in our behaviors. In this paper, the concept and the research framework of MyFinder proposed by the authors...

Personal identity might seem a central concept in the consideration of immortality and other transhumanist endeavors. However, Ettinger and Parfit demonstrate the non-cruciality of personal identity, and separate personal identity from the person and the continuity of personal experience. Philosophers Derrida, Simondon, and Deleuze continue by refo...

Disease risk prediction (DRP) is one of the most important challenges in personal genome research. Although many direct-to-consumer genetic test (DTC) companies have begun to offer personal genome services for DRP, there is still no consensus on what constitutes a gold-standard service. Here, we systematically evaluated the distributions of DRPs fr...

A key contemporary trend emerging in big data science is the quantified self (QS)–individuals engaged in the self-tracking of any kind of biological, physical, behavioral, or environmental information as n=1 individuals or in groups. There are opportunities for big data scientists to develop new models to support QS data collection, integration, an...

A significant shift is underway as the fields of health and biology are re-organizing into the larger ecosystems of information sciences and complexity sciences. The era of big data is transforming all economic sectors including health and biology. Three big health data streams are being integrated into a standardized investigative method in the re...

Understanding the human mind and increasing individual happiness are important goals in Artificial Intelligence (AI) and well-being science. The recent revolution in portable self-tracking devices in the data-driven wellness movement and participatory-driven wellness communities, such as the Quantified Self community, provides us with new opportuni...

The concepts of health and health care are moving towards the notion of personalized preventive health maintenance and away from an exclusive focus on the cure of disease. This is against the backdrop of contemporary public health challenges that include increasing costs, worsening outcomes, 'diabesity' epidemics, and anticipated physician shortage...

The number of devices on the Internet exceeded the number of people on the Internet in 2008, and is estimated to reach 50 billion in 2020. A wide-ranging Internet of Things (IOT) ecosystem is emerging to support the process of connecting real-world objects like buildings, roads, household appliances, and human bodies to the Internet via sensors and...

Stem cell research could have a significant near-term public health impact with applications in cell-replacement therapies (treatments are in development for over 50 diseases), disease modeling and drug discovery. Recent advances have been achieved in techniques for reprogramming somatic cells directly to neurons and neural stem cells, and in diffe...

Crowdsourced health research studies are the nexus of three contemporary trends: 1) citizen science (non-professionally trained individuals conducting science-related activities); 2) crowdsourcing (use of web-based technologies to recruit project participants); and 3) medicine 2.0 / health 2.0 (active participation of individuals in their health ca...

Accessing crowdsourced cohorts for health studies is a significant emerging opportunity that could have a positive impact on public health research, particularly as outcomes shift to the personalized, preventive medicine of the future. Health social networks have grown to become some of the largest aggregate patient registries and offer cost and ef...

The current era of internet-facilitated bigger data, better tools, and collective intelligence community computing is accelerating advances in many areas ranging from artificial intelligence to knowledge generation to public health. In the health sector, data volumes are growing with genomic, phenotypic, microbiomic, metabolomic, self-tracking, and...

Stem cell research and related therapies (including regenerative medicine and cellular therapies) could have a significant near-term impact on worldwide public health and aging. One reason is the industry's strong linkage between policy, science, industry, and patient advocacy, as was clear in the attendance and programming at the 7(th) annual Worl...

The focus of the 2011 American Aging Association meeting was emerging concepts in the mechanisms of aging. Many of the usual topics in aging were covered, such as dietary restriction (DR), inflammation, stress resistance, homeostasis and proteasome activity, sarcopenia, and neural degeneration. There was also discussion of newer methods, such as mi...

Gene carrier status and pharmacogenomic data may be detectable from single nucleotide polymorphisms (SNPs), but SNP-based research concerning multigenic common disease such as diabetes, cancers, and cardiovascular disease is an emerging field. The many SNPs and loci that may relate to common disease have not yet been comprehensively identified and...

Information optimization is a centerpiece phenomenon in the universe. It develops from simplicity, then continuously breaks symmetry and cycles through instability to progress to increasingly dense nodes of complexity and diversity. Intelligence has arisen as the information optimization node with the greatest complexity. A contemporary imbalance i...

A new class of patient-driven health care services is emerging to supplement and extend traditional health care delivery models and empower patient self-care. Patient-driven health care can be characterized as having an increased level of information flow, transparency, customization, collaboration and patient choice and responsibility-taking, as w...

Modern methods of production have given us the possibility of ease and security for all; we have chosen, instead, to have overwork for some and starvation for the others. Hitherto we have continued to be as energetic as we were before there were machines; in this we have been foolish, but there is no reason to go on being foolish for ever." – Bertr...