Melanie Rees-Roberts- Bachelor of Science
- Senior Research Fellow at University of Kent
Melanie Rees-Roberts
- Bachelor of Science
- Senior Research Fellow at University of Kent
About
30
Publications
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Introduction
I am a senior research fellow and split my time between working on my own research portfolio based at the Centre for Health Services Studies, University of Kent, and as a senior research fellow leading on research delivery and impact for the National Institute for Health Research Applied Research Collaboration Kent Surrey Sussex.
I have been working in health and clinical research for over 15 years. In that time, I have built collaborations with academics, clinicians and multi-disciplinary heal
Current institution
Publications
Publications (30)
Objectives
The aim of this study was to determine the feasibility of delivering personalised isometric exercise (IE) for people with stage 1 hypertension. Is it feasible to deliver an isometric wall squat intervention in the National Health Service and what sample size is required to conduct an appropriately powered effectiveness randomised control...
Background Opioids are frequently prescribed for short-term acute pain following surgery. Used appropriately, opioids deliver extremely favourable pain relief. Used longer than 90-days, however, can result in health complications, including unintentional overdose and addiction. Globally, >40 million people are dependent on opioids and annually >100...
Background Opioids are frequently prescribed for short-term acute pain following surgery. Used appropriately, opioids deliver extremely favourable pain relief. Used longer than 90-days, however, can result in health complications, including unintentional overdose and addiction. Globally, >40 million people are dependent on opioids and annually >100...
Introduction
In England, life expectancy has stalled and significant decreases observed in certain geographical areas and populations. The cause of this involves complex dynamics between an individual’s health, characteristics, lifestyle, and their wider environment known as the wider determinants of health which are key to good life expectancy, he...
Background
Healthy lifestyle changes for patients with stage 1 hypertension are recommended before antihypertensive medication. Exercise has antihypertensive benefits; however, low adoption and high attrition are common. Patients need easily adoptable, effective and manageable exercise interventions that can be sustained for life. We present partic...
Background Opioids are frequently prescribed for short-term acute pain following surgery. Used appropriately, opioids deliver extremely favourable pain relief. Used longer than 90-days, however, can result in health complications, including unintentional overdose and addiction. Globally, >40 million people are dependent on opioids and annually >100...
Objective
Adherence is low to the lifestyle changes recommended by NICE for patients with hypertension. More easily adopted, effective and manageable exercise interventions are needed. This study determined the feasibility of personalised isometric exercise (IE) for patients with Stage (grade) 1 hypertension in the National Health Service (NHS) in...
Objective
Isometric exercise training (IET) is consistently shown to reduce blood pressure (BP). We recently investigated the feasibility of delivering a personalised isometric wall-squat protocol to patients with Stage-1 hypertension within a free-to-access healthcare setting. Whist healthcare professionals (HCP) and patients thought the intervent...
BACKGROUND: Hypertension affects 1:4 adults and increases the risk of CV disease. Management aims to reduce blood pressure to a level that minimizes risk; up to 50% of people don't achieve blood pressure targets often due to insufficient treatment or poor adherence. Exercise has a role to play in the management of hypertension. The impact of isomet...
Background
Hospice-at-home aims to enable patients approaching end-of-life to die at home and support their carers. A wide range of different service models exists but synthesised evidence on how best to support family carers to provide sustainable end-of-life care at home is limited.
Aim
To explore what works best to promote family carers’ experi...
The COVID-19 pandemic has significantly impacted on the delivery of clinical trials in the UK, posing complicated organisational challenges and requiring adaptations, especially to exercise intervention studies based in the community. We aim to identify the challenges of public involvement, recruitment, consent, follow-up, intervention and the heal...
Background: In the United Kingdom National Health Service (NHS), digital transformation programmes have resulted in the creation of pseudonymised linked datasets of patient-level medical records across all NHS and social care services. In the Southeast England counties of East and West Sussex, public health intelligence analysts based in local auth...
IntroductionDigital programmes in the newly created NHS integrated care boards (ICBs) in the United Kingdom mean that curation and linkage of anonymised patient data is underway in many areas for the first time. In Kent, Surrey and Sussex (KSS), in Southeast England, public health teams want to use these datasets to answer strategic population heal...
Objectives
In Kent, Surrey and Sussex (KSS), linked health and social care datasets are in set-up phase in NHS integrated care systems (ICS), and governance models for using data for planning and research are under development. This represented an exceptional opportunity to consult with KSS citizens and work together to identify how ICSs in KSS can...
Background
Many people prefer to die at home when the time comes. Hospice at home services aim to support patients to achieve this. A range of hospice at home services exist; some services have been evaluated, but there has been limited evidence synthesis.
Objectives
The main objective was to find out what models of hospice at home services work b...
The counties of Kent, Surrey and Sussex (KSS) in South East England are creating anonymized, linked databases of healthcare records for audit, service planning and research for the first time. We consulted with 79 citizens from KSS in 5 deliberative focus groups, asking about perceived benefits and concerns regarding these new data assets. Particip...
Background
Hypertension (HTN) affects approximately 25% of the UK population and is a leading cause of mortality. Associated annual health care costs run into billions. National treatment guidance includes initial lifestyle advice, followed by anti-hypertensive medication if blood pressure (BP) remains high. However, adoption and adherence to recom...
Background: Hypertension (HTN) affects approximately 25% of the UK population and is a leading cause of mortality. Associated annual health care costs run into billions. National treatment guidance includes initial lifestyle advice, followed by anti-hypertensive medication if blood pressure (BP) remains high. However, adoption and adherence to reco...
Background
Growing prevalence of atrial fibrillation (AF) in the ageing population and its associated life-changing health and resource implications have led to a need to improve its early detection. Primary care is an ideal place to screen for AF; however, this is limited by shortages in general practitioner (GP) resources. Recent increases in the...
Objective
Hospice at Home (HAH) services aim to enable patients to be cared for and die at home, if that is their choice and achieve a ‘good death’. A national survey, in 2017, aimed to describe and compare the features of HAH services and understand key enablers to service provision.
Methods
Service managers of adult HAH services in the ‘Hospice...
Background:
The clinical utility of interferon-γ release assays (IGRAs) for diagnosis of active tuberculosis is unclear, although they are commonly used in countries with a low incidence of tuberculosis. We aimed to resolve this clinical uncertainty by determining the accuracy and utility of commercially available and second-generation IGRAs in th...
Background
Interferon gamma release assays (IGRAs) are blood tests recommended for the diagnosis of tuberculosis (TB) infection. There is currently uncertainty about the role and clinical utility of IGRAs in the diagnostic workup of suspected active TB in routine NHS clinical practice.
Objectives
To compare the diagnostic accuracy and cost-effecti...
Background The role of interferon-gamma release assays (IGRAs) in diagnosis of active tuberculosis (TB) is unclear, yet they are commonly used in low-TB-incidence countries. This study sought to resolve this clinical uncertainty by determining the diagnostic accuracy and role of current and second-generation IGRAs in the diagnostic assessment of su...
Background:
Tackling tuberculosis requires testing and treatment of latent tuberculosis in high-risk groups. The aim of this study was to estimate the predictive values of the tuberculin skin test (TST) and two interferon-γ release assays (IGRAs) for the development of active tuberculosis in high-risk groups-ie, people in recent contact with activ...
We conducted a cross-sectional analysis of baseline data from a UK cohort study which enrolled participants at risk of latent tuberculosis infection (LTBI, defined as a positive result for either of the two interferon gamma release assays). Binomial regression with a log link was used to estimate crude and adjusted prevalence ratios (PRs) and 95% C...
Introduction
Atrial fibrillation (AF) affects >6% of people aged 65 years or older. Left undetected and untreated, patients may develop significant cardiovascular complications and have a fivefold increased risk of suffering a stroke. For 40% of all sufferers, AF can be asymptomatic. Every year in the UK, £2.2 billion is spent on AF-related strokes...
Background
Tackling tuberculosis (TB) requires testing and treatment of high-risk groups for latent tuberculosis infection. We estimated the predictive values of the tuberculin skin test (TST) and interferon gamma release assays (IGRAs) for development of active TB in migrants and contacts of active TB patients in the UK.
Methods
Participants were...
