Melania Maria Ramos Amorim

Melania Maria Ramos Amorim
Instituto de Medicina Integral Professor Fernando Figueira | IMIP · Department of Obstetrics and Gynecology

MD, PhD
Professor of Obstetrics and Gynecology; Professor of Postgraduate Program of Integral Medicine

About

355
Publications
73,280
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4,241
Citations
Introduction
Obstetrician and Gynaecologist, professor and researcher. Feminist and activist for sexual and reproductve rights. Main interests: Evidence-Based Medicine, High-Risk Pregnancy, Hypertension in Pregnancy, Humanization of Childbirth, Maternal Mortality, Abortion, Congenital Zika Virus and Translational Research. Currently teachs in UFCG (Campina Grande, Brazil) and IMIP (Recife, Brazil). She has a H-index of 43 (Scholar Google),25(Scopus) and 26(Web of Science). Mother of two autistic children.
Additional affiliations
May 2002 - present
Universidade Federal de Campina Grande (UFCG)
Position
  • Professor (Associate)
Description
  • Professor of Obstetrics and Gynecology
May 2002 - present
Universidade Federal de Campina Grande (UFCG)
Position
  • Professor (Associate)
March 1996 - present
Instituto de Medicina Integral Professor Fernando Figueira
Position
  • Professor (Associate)
Description
  • Professor of the Post-Graduate Program on Maternal and Child Health
Education
March 1984 - December 1989
Universidade Federal da Paraíba
Field of study
  • Medicine

Publications

Publications (355)
Article
Background and purpose: Most women suffer some degree of perineal trauma during vaginal delivery. Second stage management strategies, including vocalization, to protect the perineum have been investigated. Objective: To compare the frequency and degree of perineal trauma at vaginal delivery, with and without use of the vocalization maneuver duri...
Article
Objective: To describe the urological outcomes in children with congenital Zika syndrome (CZS) and investigate the relationship between clinical and urological findings in this population. Methods: This cross-sectional study involved children with CZS followed up by a referral center for children with microcephaly in the state of Paraiba in nort...
Article
To determine the association between soluble FMS-like tyrosine kinase-1 (sFlt-1) and high-sensitivity C-reactive protein (hs-CRP) with maternal and perinatal outcomes in patients with preeclampsia (PE) with severe features. A cohort study was conducted on 100 patients, 60 with PE with severe features, and 40 healthy women in the third trimester of...
Article
Full-text available
The World Health Organization (WHO) recently published a new recommendation on the use of the uterine balloon tamponade for the treatment of post-partum hemorrhage. The recommendation that uter-ine balloon tamponade should be used only where there is already access to other postpartum hemorrhage treatments (including immediate recourse to surgery)...
Article
This meta-analysis aimed to evaluate, using the best level of evidence, the possible benefits and advantages of using peanut ball (PB) in women with an epidural during labour on the maternal and neonatal outcomes. This research was conducted using MEDLINE/PubMed, Embase, LILACS, CINAHL, CENTRAL, PEDro, Web of Science and SCOPUS databases, with no p...
Chapter
Postpartum complications can lead to severe maternal morbidity and mortality. More than half of maternal deaths that occurred in Brazil occurred during the postpartum period. The main direct causes of maternal death are hypertension, hemorrhage, and sepsis. Embolisms are another complication which can occur postpartum and cause maternal deaths. For...
Conference Paper
Abstract: Objectives: To provide an overview of deaths due to COVID19 Acute Respiratory Distress Syndrome (ARDS) among obstetric patients in Brazil, until March 2021,using surveillance system (SS) data. Methods: By March 8, 2021, we identified fatal cases of COVID19 in pregnant and postpartum women reported to the Brazilian Ministry of Health's ARD...
Article
Full-text available
Objectives: Social detachment has been considered the most effec�tive preventive measure to control the transmission of COVID-19. However, its consequences may be negative when it comes to the development or worsening of mental disorders. We aimed to deter�mine the factors associated with the signs and symptoms of severe/ extreme depression in wo...
Article
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Objectives: Women with breast cancer show high prevalence of mental disorders, which can be higher during COVID-19 period. Given the above, we aimed to determine factors associated with the symptomatology of anxiety and depression in women with breast cancer during social distancing. Methods: Cross-sectional study conducted between July and Se...
Article
To describe the clinical profile, management, maternal outcomes and factors associated with severe maternal outcome (SMO) in patients admitted for eclampsia. A retrospective cohort study was carried out. All women admitted to the Obstetric Intensive Care Unit (ICU) at Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Northeast...
Article
Full-text available
In several countries, midwives and/or obstetric nurses provide primary care for pregnant women. In the Supplementary Health System in Brazil, coverage of antenatal care is mandatory, and carried out by obstetricians. The objective of this study is to conduct a cost-effectiveness analysis, comparing clinical outcomes and costs associated with the in...
Article
Objective: To compare risk of death due to COVID-19 among pregnant, postpartum, and non-pregnant women of reproductive age in Brazil, using the severe acute respiratory syndrome surveillance system (SARS-SS). Methods: A secondary analysis was performed of the Brazilian official SARS-SS, with data retrieved up to August 17, 2020. Cases were strat...
Preprint
Full-text available
Background: In Brazil, a 20% increase in maternal mortality rate due to COVID-19 is projected for 2020. On January 4, 2021, the P.1 SARS-CoV-2 genetic variant was firstly identified in the country and recent data has indicated an association with higher hospitalization rates and mortality. The impact of P.1 variant in the obstetric population remai...
Article
Full-text available
Objetivos: revisar a literatura disponível sobre a COVID-19 e seus aspectos maternos e perinatais. Métodos: uma revisão narrativa de literatura foi realizada nos meses de março a setembro de 2020, utilizando os descritores, coronavirus, Covid 19, SARS-CoV-2, pregnancy, gravidity, pregnancy complications e pregnancy complications infectius. Foram in...
Article
Full-text available
Despite great advances in our knowledge of the consequences of Zika virus to human health, many questions remain unanswered, and results are often inconsistent. The small sample size of individual studies has limited inference about the spectrum of congenital Zika manifestations and the prognosis of affected children. The Brazilian Zika Cohorts Con...
Article
Full-text available
Objectives: to review the available literature on the general aspects of SARS-CoV-2 infec-tion. Methods: this is a narrative literature review carried out from March to September 2020. Results: COVID-19 caused by the new coronavirus or SARS-CoV-2, grows with devas-tating effects worldwide. The literature describes epidemiological data and mortali...
Article
Full-text available
SARS-CoV-2, the new coronavirus of severe acute respiratory syndrome, which causes a predominantly respiratory disease called COVID-19, quickly caused a pandemic, due to its high transmissibility, leaving a trail of deaths around the world. Initially, the pregnancy puerperal cycle was not associated with complications and mortality, only later was...
Article
Full-text available
Objetivos: revisar a literatura disponível sobre os aspectos gerais dainfecção por SARS-CoV-2. Métodos: trata-se de uma revisão narrativa de literatura realizada nos meses de março asetembro de 2020. Resultados: a COVID-19, causada pelo novo coronavírus ou SARS-CoV-2, cresce com efeitos devastadores em todo o mundo. A literetura descreve dados epid...
Article
Aim: To identify abnormalities in muscle tone and motor function associated with congenital Zika syndrome (CZS). Method: A cross-sectional observational study involving 96 children (55 males) with CZS at a mean (SD) age 35.2 ± 2.9 months. Children’s muscle tone was investigated using the pull to sit, scarf sign, shoulder suspension and ventral susp...
Article
Full-text available
Objectives: reviewing the available literature on COVID-19 infection and the maternal and perinatal outcomes. Methods: this is a narrative review of the literature carried out from March to September 2020, usingthe MESH: coronavirus, Covid 19, SARS-CoV-2, pregnancy, gravidity, pregnancy complications and pregnancy complications infectius. All study...
Article
Full-text available
Improving understanding of the prognostic factors associated with death resulting from sepsis in obstetric patients is essential to allow management to be optimized. This retrospective cohort study aimed to determine the risk factors for death in patients with sepsis admitted to the obstetric intensive care unit of a tertiary teaching hospital in n...
Article
Introdução: em dezembro de 2019, foi identificada uma nova variação do coronavírus, altamente transmissível, denominado SARS-CoV-2, causando a doença posteriormente nomeada como COVID-19. Apesar de muitos estudos já publicados em tão curto espaço de tempo sobre a doença, ainda há muitas dúvidas em relação a assuntos mais específicos, como a gestaçã...
Article
Full-text available
Objective: To describe clinical characteristics of pregnant and postpartum women with severe COVID-19 in Brazil and to examine risk factors for mortality DESIGN: Cross-sectional study based on secondary surveillance database analysis SETTING: Nationwide Brazil POPULATION OR SAMPLE: 978 Brazilian pregnant and postpartum women notified as COVID-19 A...
Article
Full-text available
Sir, We carefully read the work by Mendoza et al.,1 a prospective observational study including 42 women, eight with severe and 34 with non‐severe coronavirus disease 2019 (COVID‐19) pneumonia. Six women presented signs and symptoms of pre‐eclampsia and were assessed with uterine artery pulsatility index (UtAPI) and angiogenic factors (soluble fms...
Article
Full-text available
Objective To evaluate whether clinical and social risk factors are associated with negative outcomes for COVID‐19 disease among Brazilian pregnant and postpartum women. Methods A secondary analysis was conducted of the official Acute Respiratory Syndrome Surveillance System database. Pregnant and postpartum women diagnosed with COVID‐19 ARDS until...
Article
Objective: To investigate the impact of intensive physiotherapy training on the motor function of children with congenital Zika syndrome (CZS). Design: A retrospective cohort study. Setting: A support center for children with microcephaly. Participants: Seven children 14-18 months old, diagnosed with CZS and previously monitored over one yea...
Article
Full-text available
This is a letter commenting a systematic review about maternal and perinatal mortality and vertical transmission associated with COVID-19
Article
We read with great interest the results of the cross-sectional study and community-based surveys, presented by Meghan Bohren and colleagues,1 showing that more than a third of women experienced mistreatment during childbirth. Younger and less educated women were most at risk, suggesting inequalities in treatment during childbirth.1 In 2014, WHO dec...
Article
Objective: To describe obstetric and perinatal outcomes in cases of congenital Zika syndrome (CZS). Methods: A dual prospective and retrospective cohort study involving 102 pairs of mothers and fetuses/children with CZS whose infection was confirmed by testing for the Zika virus in amniotic fluid, umbilical cord blood and fragments from the plac...
Article
Full-text available
The concept of preemptive analgesia, albeit long-standing, has reemerged. Consequently, recent research has focused on testing a variety of drugs preoperatively to prevent the occurrence of postoperative pain, a major factor of morbidity. Amitriptyline is a tricyclic antidepressant used to treat chronic pain. Because amitriptyline acts on pain tran...
Article
We examined the Brazilian Acute Respiratory Distress Syndrome Surveillance System searching from COVID-19 ARDS cases among pregnant women with complete data on ethnicity until July 14, 2020. Black women had similar mean age and morbidity profile as compared to White women, but were hospitalized in worse conditions, had a higher rate of ICU admissio...
Article
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Dear Editor, Tai and collaborators raised important questions about the potential biomedical factors and social determinants that play a role in the observed racial disparities on COVID-19 outcomes in the US[1]. Evidence of such disproportionate impact is also arising on historically oppressed ethnic groups in Brazil, current worldwide pandemic epi...
Article
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To the Editors: We carefully read the work by Sagi-Dain et al. [1], a random-ized clinical trial (RCT) asking whether it is time to abandon episiotomy. We congratulate the authors for choosing this theme, we have followed EPITRIAL since the publication of its interim analysis [2]. Routine episiotomy should not be performed, but whether any episioto...
Article
Full-text available
Initial reports at the onset of the COVID‐19 pandemic indicated that the obstetric population did not appear to be at higher risk of developing severe symptoms of COVID‐19 than the general population.[1] However, following recent publications showing that pregnancy and the postpartum period might indeed pose additional risks for both women and babi...
Article
Objective: To describe eight cases of women who became pregnant after a previous pregnancy that resulted in a fetus with congenital Zika syndrome (CZS). Methods: A prospective case series follow up study of all children of mothers that were pregnant with a fetus with CZS epidemics and delivered in a subsequent pregnancy. Head circumference at bi...
Article
Full-text available
Objective The aim of this study was to collect and analyze data from different sources to have a general overview of COVID-19-related maternal deaths in Brazil, as well as to compare data with worldwide reports. Study design We systematically searched data about COVID-19 maternal deaths from the Brazilian Ministry of Health surveillance system, St...
Article
Full-text available
Despite being a relatively new term, obstetric violence is an old problem. In 2014, the World Health Organization declared: “Many women experience disrespectful and abusive treatment during childbirth in facilities worldwide. Such treatment not only violates the rights of women to respectful care, but can also threaten their rights to life, health,...
Article
Full-text available
Objective: To assess fetal visceral adiposity and associated factors during pregnancy. Methods: Secondary analysis of prospective cohort data with 172 pairs (pregnant woman/fetus) treated at public health units. Anthropometric data, metabolic (glucose, glycated hemoglobin, insulin, insulin resistance, total cholesterol and fractions, triglycerides)...
Article
Full-text available
Background: Labor induction is defined as any procedure that stimulates uterine contractions before labor begins spontaneously. The vaginal and oral routes of administration of misoprostol are those most used for the induction of labor in routine practice, with the recommended dose being 25 μg. Nevertheless, the sublingual route may reduce the num...
Preprint
Full-text available
Background: Labor induction is defined as any procedure that stimulates uterine contractions before labor begins spontaneously. The vaginal and oral routes of administration of misoprostol are those most used for the induction of labor in routine practice, with the recommended dose being 25 μg. Nevertheless, the sublingual route may reduce the numb...
Article
Background Congenital Zika syndrome causes a spectrum of neurological symptoms with varying effects on function that require different therapeutic strategies. To date, this spectrum of effects and its clinical implications have not been completely described. We describe the neurological examination findings in toddlers and preschoolers, including p...
Preprint
Full-text available
Background: Labor induction is defined as any procedure that stimulates uterine contractions before labor begins spontaneously. The vaginal and oral routes of administration of misoprostol are those most used for the induction of labor in routine practice, with the recommended dose being 25 μg. Nevertheless, the sublingual route may reduce the numb...
Article
Full-text available
OBJECTIVE Evaluate the prevalence of metabolic syndrome (MS) and the main associated maternal factors in women without pre-gestational conditions, in early pregnancy and in the immediate postpartum. METHODS Two hundred pregnant women were evaluated at the 16th week of pregnancy, and 187 were reassessed postpartum. MS was diagnosed according to the...
Article
Objective: To determine the effectiveness of an oral versus sublingual loading dose of nifedipine for tocolysis. Methods: An open, randomized clinical trial conducted between March 1, 2013, and April 31, 2014. Participants were pregnant women with a diagnosis of premature labor, single live fetus, topical pregnancy, gestational age 24-36 weeks,...
Article
Full-text available
Objective To determine the prevalence of episiotomy and the factors associated with the knowledge, attitude and practice (KAP) of Brazilian obstetricians in relation to this procedure. Methods A KAP survey was conducted with obstetricians working in Brazil. An electronic form containing structured questions previously evaluated using the Delphi met...
Article
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The association of body mass index (BMI) and gestational weight gain (GWG) with preterm birth (PTB) remains controversial in the literature. To evaluate different maternal BMI and GWG categories, according to the initial BMI, in relation to different PTB subtypes and perinatal outcomes, we conducted a secondary analysis of a multicentre cross-secti...
Article
Full-text available
Objective To determine the prevalence of sexual dysfunction and its associated factors in pregnant women. Methods A descriptive, cross-sectional study including 262 pregnant women aged 18 years or older with gestational age between 10 and 35 weeks. Women with urinary tract infections and conditions of gestational risk were excluded. The Pregnancy S...
Article
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Objective To describe the epidemiological, clinical and laboratory profiles of women with anal neoplasia associated with cervical neoplasia attending a tertiary healthcare facility in northeastern Brazil. Methods This epidemiological, descriptive study was conducted using a database from a cross-sectional study carried out between December 2008 and...
Article
Full-text available
Resumo Objetivo Determinar o efeito da caminhada em esteira sobre a frequência cardíaca materna (FCM) e parâmetros cardiotocográficos (batimentos cardiofetais basais [BCFs], movimentos ativos fetais [MAFs], número de acelerações e desacelerações e variabilidade de curta [STV] e longa [LTV] duração da frequência cardíaca fetal) em gestantes na 36a s...
Article
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Abstract Objectives: to determine the incidence of the main high oncogenic risk types of the human papillomavirus (HPV) ( 16, 18, 31 and 33) and the risk factors for cervical adenocarcinoma. Methods: a case-control study was carried out with 324 women (69 with adenocarcinoma and 260 healthy controls) between 2001 and 2014. Information on risk facto...
Article
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Background: To investigate the association between sociodemographic and obstetric variables and delays in care with maternal near misses (MNMs) and their health indicators. Methods: A prospective cohort study was conducted at a high-risk maternity hospital in northeastern Brazil from June 2015 to May 2016 that included all pregnant women seen at...
Article
Full-text available
Background: Magnesium sulfate is the ideal drug for the prevention and treatment of eclampsia. Nevertheless, the best regimen for protection against eclampsia with minimal side effects remains to be established. This study aimed to compare serum magnesium levels during intravenous infusion of magnesium sulfate at 1 gram/hour versus 2 grams/hour as...
Article
Full-text available
Objective: To determine the prevalence of anal HPV genotypes and associated factors in women with pre-malignant lesion or cancer in the cervix and anal canal. Methods: A prospective, cross-sectional study analyzed DNA samples taken from women with cervical pre-malignant lesions or cancer to identify anal HPV by polymerase chain reaction (PCR). T...