
Mehran Emadi Andani- Ph.D. Biomedical Engineer
- Research Fellow at University of Verona
Mehran Emadi Andani
- Ph.D. Biomedical Engineer
- Research Fellow at University of Verona
About
86
Publications
27,991
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
622
Citations
Introduction
Current institution
Additional affiliations
Education
September 2003 - March 2009
September 1996 - September 1999
September 1991 - September 1996
Publications
Publications (86)
Deep brain stimulation (DBS) is an efficient therapy to control movement disorders of Parkinson's tremor. Stimulation of one area of basal ganglia (BG) by DBS with no feedback is the prevalent opinion. Reduction of additional stimulatory signal delivered to the brain is the advantage of using feedback. This results in reduction of side effects caus...
Balance control is essential to maintain a stable body position and to prevent falls. The aim of this study was to determine whether balance control could be improved by using cerebellar transcranial direct current stimulation (tDCS) and visual feedback in a combined approach. A total of 90 healthy volunteers were randomly assigned to six groups de...
Human motor planning combines such interesting aspects as modular organization in motor primitives and characteristics of stochastic optimality. Motor primitives aided in the description of motor skill learning. In this study, for the first time, an interpretation is proposed to explain how motor primitives are shaped in a stochastic optimality pro...
A new set of basis functions is presented. The foundation in mathematics is established. To reconstruct a signal, it is compared to the Fourier basis functions. The M-basis functions' potential applications are also presented.
A signal can be represented by a linear combination of M-basis functions. By increasing the order of M-basis functions, the...
Service robots are deployed in sport applications for coaching, logistics, security, and crowd management. In this chapter, an experimental setup is used for the implementation of SLAM algorithm in a sports AGV framework to evaluate the precision of the auto-parking test using ROS, STAGE, and RVIZ simulators for comparisons against experimental res...
The aim of this study is to investigate whether expectancy, induced through a placebo procedure, favors the activation of the corticospinal tract before movement initiation. By adopting the premovement facilitation paradigm, we applied transcranial magnetic stimulation over the left or right primary motor cortex at rest and 100 ms or 50 ms before m...
Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by a range of motor and non-motor symptoms (NMSs) that significantly impact patients’ quality of life. This review aims to synthesize the current literature on the application of brain stimulation techniques, including non-invasive methods such as transcranial magnet...
Purpose
Theta-burst stimulation (TBS) over the primary motor cortex modulates activity of the underlying neural tissue, but little is known about its consequence on neuromuscular fatigue (NMF) and its neural correlates. This study aimed to compare the effects of facilitatory versus inhibitory TBS on the NMF and excitability/inhibition of the cortic...
Toe-in and toe-out angles show difficulties in assessing and addressing gait abnormalities, posture issues, and joint stress, requiring sophisticated monitoring and treatment strategies in musculoskeletal health. Diagnostic and Detecting toe-in/out angles is important because of its rules and index into gait abnormalities, posture imbalances, and p...
Nowadays, Sitting is one of the frequent activities of humans. particularly with the rise of office work, which is leading to an increase in the sitting periods for many individuals. Research highlights the importance of studying sitting posture to enhance seat quality, correct sitting methods, and prevent various health issues like neck and should...
Objective
Existing literature indicates that females generally demonstrate higher fatigue resistance than males during isometric contractions. However, when it comes to single-limb dynamic exercises, the intricate interplay between performance fatigability (PF), cardiovascular responses, and muscle metabolism in relation to sex differences remains...
Micro robots, miniature robotic devices typically ranging from micrometers to a few millimeters in size, hold immense potential in various fields, particularly healthcare. Their diminutive stature enables access to intricate anatomical regions previously unreachable, facilitating targeted drug delivery, localized treatment, and precise monitoring....
Aim: Force expression is characterized by an interplay of biological and molecu- lar determinants that are expected to differentiate males and females in terms of maximal performance. These include muscle characteristics (muscle size, fiber type, contractility), neuromuscular regulation (central and peripheral factors of force expression), and indi...
Forward Head Posture (FHP) is when the head leans forward due to factors such as heavy backpacks or poor computer ergonomics. FHP can lead to neck strain and discomfort as well as potential long-term issues such as arthritis. Treatment options include specialized exercises, orthopedic devices, manual therapy, physical exercises, and visual feedback...
The present study explores whether a particular style of placebo disclosure could serve as a tool to foster a renewed trust in one's own inherent resources and elicit a meaningful placebo effect. In a motor performance task, two placebo groups received inert transcutaneous electrical nerve stimulation (TENS) in each of four sessions along with info...
Background: Sleep is a critical factor in maintaining good health, and its impact on various diseases has been recognized by scientists. Understanding sleep patterns and quality is crucial for investigating sleep-related disorders and their potential links to health conditions. The development of non-intrusive and contactless methods for analyzing...
Purpose
This paper aims to explore and review the potential of robotic rehabilitation as a treatment approach for Alzheimer’s disease (AD) and its impact on the health and quality of life of AD patients.
Design/methodology/approach
The present discourse endeavors to provide a comprehensive overview of extant scholarly inquiries that have examined...
In studying neuromuscular fatigability, researchers commonly use functional criteria to position and hold the transcranial magnetic stimulation (TMS) coil during testing sessions. This could influence the magnitude of corticospinal excitability and inhibition responses due to imprecise and unsteady positions of the coil. To reduce coil position and...
The ability to perform two tasks simultaneously is essential for daily activities. In older adults, this ability is markedly reduced, as evidenced by the dual-task cost on gait. Preliminary evidences indicate that the dual-task cost can be influenced by different types of manipulations. Here, we explored the effectiveness of a new approach to reduc...
When interacting with the environment, sensory information is essential to guide movements. Picking up the appropriate sensory information (both visual and auditory) about the progression of an event is required to reach the right place at the right time. In this study, we aimed to see if general tau theory could explain the audiovisual guidance of...
Getting proper rest is an essential issue, but it is neglected as the major component of every person’s overall health and well-being. Enough proper rest has a lot of proven health benefits. This paper aims at proposing a systematic framework to find the suitable pillows and mattresses for individuals to have proper rest and sleep. The proposed sys...
Nowadays Unmanned aerial vehicles (UAV) are
used in various applications. One of the domains that they are
recently hired on is remote sensing applications which they
should detect and identify the object. Till today various
algorithms are proposed but among them SIFT, SURF, ORB
and BRISK are more famous but based on the author's
resources th...
The placebo effect is a powerful psychobiological phenomenon whereby a positive outcome follows the administration of an inert treatment thought to be effective. Growing evidence shows that the placebo effect extends beyond the healing context, affecting also motor performance. Here we explored the placebo effect on the control of goal-directed mov...
Purpose:
Transcranial magnetic stimulation (TMS) is a noninvasive technique to assess corticospinal excitability and inhibition. TMS over the motor cortex during a voluntary contraction elicits short-latency excitatory (motor-evoked potential, MEP) and inhibitory (silent period, SP) responses in the target muscle. However, the technique for search...
Non-invasive brain stimulation (NIBS) techniques are used in clinical and cognitive neuroscience to induce a mild magnetic or electric field in the brain to modulate behavior and cortical activation. Despite the great body of literature demonstrating promising results, unexpected or even paradoxical outcomes are sometimes observed. This might be du...
Changes in corticospinal excitability have been well documented in the preparatory period before movement, however, their mechanisms and physiological role have not been entirely elucidated. We aimed to investigate the functional changes of excitatory corticospinal circuits during a reaction time (RT) motor task (thumb abduction) in healthy subject...
Background
Tau theory explains how both intrinsically and perceptually guided movements are controlled by the brain. According to general tau theory, voluntary, self-paced human movements are controlled by coupling the tau of the movement (i.e., the rate of closure of the movement gap at its current closure rate) onto an intrinsically generated tau...
Motor learning is a key component of human motor functions. Repeated practice is essential to gain proficiency over time but may induce fatigue. The aim of this study was to determine whether motor performance and motor learning (as assessed with the serial reaction time task, SRTT) and perceived fatigability (as assessed with subjective scales) ar...
Hypnosis can be considered an altered state of consciousness in which individuals produce movements under suggestion without apparent voluntary control. Despite its application in contexts implying motor control, evidence for the neurophysiological mechanisms underlying hypnosis is scarce. Inter-individual differences in hypnotic susceptibility sug...
Background
Tau theory explains how both intrinsically and perceptually guided movements are controlled by the brain. According to general tau theory, voluntary, self-paced human movements are controlled by coupling the tau of the movement (i.e. the rate of closure of the movement gap at its current closure rate) onto an intrinsically generated tau-...
Perception and behavior are strongly influenced by the verbal information conveyed by other individuals (e.g., verbal suggestion) and by learning (e.g., conditioning). This influence is well represented by the placebo and nocebo effects, in which positive verbal suggestion associated with positive conditioning induces beneficial outcomes (placebo e...
Balance is a very important function that allows maintaining a stable stance needed for many daily life activities and for preventing falls. We investigated whether balance control could be improved by a placebo procedure consisting of verbal suggestion. Thirty healthy volunteers were randomized in two groups (placebo and control) and asked to perf...
One of the efficient methods in controlling the Parkinson's tremor is Deep Brain Stimulation (DBS) therapy. The stimulation of Basal Ganglia (BG) by DBS brings no feedback though the existence of feedback reduces the additional stimulatory signal delivered to the brain. So this study offers a new adaptive architecture of a closed-loop control syste...
In a recent study, we showed that tactile perception can be enhanced by applying a placebo manipulation consisting of verbal suggestion and conditioning (Fiorio et al., Neuroscience 217:96–104, 2012). Whether this change in perception is related to a better tactile functioning is still unknown. Aim of this study is to investigate whether placebo-in...
The neural correlates of the placebo effect in the motor domain are still unknown. The aim of this study was to tackle the role of a frontal cortical region, the dorsolateral prefrontal cortex (dlPFC). To this end, we stimulated the cortical site corresponding to the left dlPFC with transcranial direct current stimulation (tDCS) during a placebo pr...
Among the cognitive strategies that can facilitate motor performance in sport and physical practice,
a prominent role is played by the direction of the focus of attention and the placebo effect. Consistent evidence converges in indicating that these two cognitive functions can influence the motor outcome, although no study up-to-now tried to study...
Deep brain stimulation (DBS) is a clinical remedy to control tremor in Parkinson's disease. In DBS, one of the two main areas of basal ganglia (BG) is stimulated. This stimulation is produced with no feedback of the tremor and often causes a wide range of unpleasant side effects. Using a feedback signal from tremor, the stimulatory signal can be re...
Deep brain stimulation (DBS) is one of the most effective neurosurgical procedures to reduce Parkinsons tremor. The conventional method of DBS is open loop stimulation of one area of basal ganglia (BG). On the other hand, existing feedback causes the reduction of additional stimulatory signal delivered to the brain which results in the reduction of...
The nocebo effect in motor performance consists in a reduction of force and increase of fatigue following the application of an inert treatment that the recipient believes to be effective. This effect is variable across individuals and it is usually stronger if conditioning –exposure to the active effect of the treatment– precedes a test session, i...
In this study, a model of basal ganglia (BG) is applied to develop a deep brain stimulation controller to reduce Parkinson's tremor. Conventionally, one area in BG is stimulated, with no feedback, to control Parkinson's tremor. In this study, a new architecture is proposed to develop feedback controller as well as to stimulate two areas of BG simul...
Previous studies suggested that increasing speed has an effect on human walking features such as joints and muscles range of motion, related spatio-temporal parameters and muscles activation patterns. However, such an effect on more complicated indices e.g. muscle synergies, minimum angular jerk and cross correlation between different types of biom...
Walking is one of the most widely used movements affecting life quality. Therefore, the study of factors affecting human gait has always been an important issue. Walking speed, as a physical perturbation, affects the quality of human walking. The purpose of this study is to estimate the effects of walking speed on the short-time gait parameters. Th...
As recently demonstrated, a placebo procedure in motor performance increases force production and changes the excitability of the corticospinal system, by enhancing the amplitude of the motor evoked potentials (MEP) and reducing the duration of the cortical silent period (CSP). However, it is not clear whether these neurophysiological changes are r...
In this paper, a computational algorithm is introduced to generate energy efficient gait patterns. Each space cycle of gait has been decomposed to several phases, and boundaries of each phase are called via points. The algorithm uses six universal movement elements [1] together with kinematic information of the physical system at via points. We als...
Despite behavioral evidence showing placebo modulations of motor performance, the neurophysiological underpinnings of these effects are still unknown. By applying transcranial magnetic stimulation (TMS) over the primary motor cortex, we investigated whether a placebo modulation of force could change the excitability of the corticospinal system. Hea...
Human motion planning studies are of considerable importance in producing human-like trajectories for various industrial or clinical applications (e.g. assistive robots). In this case, the capability of Central Nervous System (CNS) in generating a large repertoire of actions can be inspirational to develop more efficient motion planning approaches....
The purpose of this work is to develop a computational model to describe the task of sit to stand (STS). STS is an important movement skill which is frequently performed in human daily activities, but has rarely been studied from the perspective of optimization principles. In this study, we compared the recorded trajectories of STS with the traject...
It is a Matlab function in order to generate minimum jerk trajectory. The function needs position, velocity and acceleration at initial and final moments.
It is a Matlab function in order to generate minimum jerk trajectory under a certain Constraint on jerk at initial and final moments; the jerk at initial and final moments is set to zero. We applied this constraint based on our observations. We figured out that the acceleration is maximum/minimum at initial and final moments of each phase of the mo...
It is a Matlab function in order to generate minimum jerk trajectory under a certain Constraint on jerk at initial and final moments; the jerk at initial and final moments is set to zero. We applied this constraint based on our observations. We figured out that the acceleration is maximum/minimum at initial and final moments of each phase of the mo...
Introduction
Our perception of the external world is strongly modulated by our own theories, experiences, beliefs and expectations. An emblematic case of this phenomenon is represented by the so-called “placebo effect”. Until now, most of the studies investigated the effects of placebo on the sensory systems, in particular on nociception.
Objectiv...
Flash and Hogan (1985) suggested that the CNS employs a minimum jerk strategy when planning any given movement. Later, Nakano et al. (1999) showed that minimum angle jerk predicts the actual arm trajectory curvature better than the minimum jerk model. Friedman and Flash (2009) confirmed this claim. Besides the behavioral support that we will discus...
Human movement science can inspire the studies in the field of robotics and rehabilitation. In this study, based on Principal Component Analysis (PCA) applied to the experimental data of Sit to Stand (STS) transfer, the basic movement patterns which contribute to form the human motion trajectories are recognized. The STS transfer is decomposed into...
A modular hierarchical structure is developed to describe human movement planning level. The modular feature of the proposed model enables it to generalize planning a task. The movements are planned based on decomposing a task into its corresponding subtasks (motion phases). There is a module responsible for one condition. The final plan is constru...
Interferential current therapy is a method of transcutaneous stimulation of deep tissues in which the undesirable activation of cutaneous nerves is minimized. While it is a well-known method in physiotherapy and diagnostic medicine, its selective property has been only described qualitatively in the literature. In this study, the effect of interfer...
It has been shown that any movement that satisfies the minimum
joint angle jerk constraint can be reproduced by linear
combination of 6 consistent Movement Elements (MEs). In this
work, we assumed that any given movement is consisted of
several successive phases (without overlap) such that each phase
satisfies the minimum joint angle jerk constrain...
In this study, based on behavioral and neurophysiological facts, a new hierarchical multi-agent architecture is proposed to model the human motor control system. Performance of the proposed structure is investigated by simulating the control of sit to stand movement. To develop the model, concepts of mixture of experts, modular structure, and some...
In this study, a hierarchical structure is proposed to model human movement control during sit-to-stand transfer. At the highest level the desired movement is planned. Then, the task to be performed is decomposed to its constitutive sub-tasks. To decompose the sit-to-stand movement, the spatial trajectory of the body center of mass is automatically...
In this study, a biologically inspired control structure to control the sit-to-stand (STS) transfer from a chair is developed and simulated. STS movement is consisted of two main phases. First phase of the movement is before leaving the seat (seat-off moment). In this phase seat reactions forces act on the body parts which are in contact with the s...
One of the factors that limit the transmission capacity of the fiber optics communication channel is the chromatic dispersion. Analyzing chromatic dispersion with high accuracy is essential for further improvement in DWDM systems as well as modern dispersion compensation techniques. In this paper, we present a new approach that can be applied for a...
Questions
Questions (5)
Researchers and Neuroscientists!
Submit your cutting-edge research to the esteemed journal "Brain Sciences" for the upcoming special issue on
"Noninvasive Neuromodulation Applications in Research and Clinics"
⏰ Submission Deadline: March 15, 2025
Visit the website for more details and to submit your research:
https://www.mdpi.com/journal/brainsci/special_issues/WYUL23PMN7
Spread the word to your colleagues and collaborators!
#CallforPapers #BrainSciencesJournal #BrainStimulation #NeuroscienceResearch
Researchers and Neuroscientists!
Submit your cutting-edge research to the esteemed journal "Brain Sciences" for the upcoming special issue on "The Impact of Posture and Movement on Intrinsic Brain Activity."
⏰ Submission Deadline: February 5, 2024
Visit our website for more details and to submit your research: https://www.mdpi.com/journal/brainsci/special_issues/XVTOSW8SH0
Spread the word to your colleagues and collaborators! Together, let's advance our understanding of how posture and movement shape the brain's functioning!
#CallforPapers #BrainSciencesJournal #Posture #Movement #IntrinsicBrainActivity #NeuroscienceResearch #FunctionalConnectivity
Dr. Mehran Emadi Andani
Guest Editor, Brain Sciences
I measured behavioral data (human body inclination) of two different groups (each, 15 subjects) in three different moments (sessions), the data was not normal (Shapiro-Wilk test) and did not respect homogeneity of variance (Levens' test). I ran non-parametric test (Mann-Whitny U test for independent comparisons and Friedman and Wilcoxon sign-rank test for paired sample comparisons).
The reviewer of my article asked me to transform data to be normal and then run parametric test (rmANOVA). I applied many transformation, only one of them was good: the LMS approach proposed by Cole and Green (1992). It is also known as LMS quantile regression with the Box-Cox transformation to normality as well as it is known as Box-Cox Cole-Green (BCCN) transformation. The formula is: Z = ((y/μ)^L-1) / (S*L), where L is a constant parameter, μ is the mean value and S is generalized coefficient of variation (i.e., σ/μ and σ is standard deviation). It is not so common transformation.
My question is: can I use any kind of transformation in the literature to transform data to meet the assumptions of parametric test in statistical analysis like rmANOVA? Or, I should just use the transformations that are famous in the field that I am working?
Many thanks in advance for your comments!
Cole TJ, Green PJ. Smoothing reference centile curves: the LMS method and penalized likelihood. Stat. Med. 1992;11:1305–1319.
I want to report the results of the statistical analysis of ordinal data. I used Wilcoxon sign-rank test for paired sample comparison and Mann-Whitney U test for independent sample comparison. My question is: to report the results, I should report median and IQR (interquartile range)? Or, I should report rank? Or, both of them? Or, something more?.. What is the correct way?
I would be very thankful if somebody help me to know what the best way is to report the results? If you send to me some references, it would be great!
Thank you!
I am eager to study the movement of patients with a disease in their motor-proprioceptive sensory information. For instance, I want to study the movement of patients whose GTO (Golgi Tendon Organ) does not work but the other proprioceptive sensory system (different receptors of muscle spindle) is working correctly. Would you please tell me if you know something about?