Mehnaaz Khuroo

Government Medical College Srinagar | GMC Srinagar · Department of Pathology

The COVID-19 has turned in to a global human tragedy and economic devastation. Governments have implemented lockdown measures, blocked international travel, and enforced other public containment measures to mitigate the virus morbidity and mortality. As of today, no drug has the power to fight the infection and bring normalcy to the utter chaos. Th...

The COVID-19 has turned in to a global human tragedy and economic devastation. Governments have implemented lockdown measures, blocked international travel, and enforced other public containment measures to mitigate the virus morbidity and mortality. As of today, no drug has the power to fight the infection and bring normalcy to the utter chaos. Th...

Background: Xanthogranulomatoussalpingo-oophoritis is an uncommon form of chronic inflammation in the genitourinary tract. Its symptoms and radiological findings mimic ovarian malignancy. Aim of this study was to evaluate the clinicopathological pattern of xanthogranulomatous salphingo oophoritis.Methods: This study was conducted in the department...

Aim: Pilonidal sinus disease is an acquired chronic inflammatory condition which is caused due to involution of hair fragment into the gluteal or natal region. This study was aimed to describe the rhomboid excision with Limberg flap reconstructuion as surgical treatment of pilonidal sinus disease in an effort to redefine the results of this techniq...

Hepatitis A is an infectious disease of the liver caused by hepatitis A virus. Hepatitis A has a global distribution with endemicity inversely proportional to higher socioeconomic conditions and standards of sanitation and hygiene. Hepatitis A virus infection is predominantly spread directly from one person to another through orofecal transmission...

Background: Tumors that occurs in children are as diverse as those in adults and present a number of challenges for the pathologist. In general, the features of malignancies in children differ biologically and histologically from those of adults with respect to incidence, type of tumor, underlying familial or genetic aberration and tendency to regr...

This study was carried out to observe the association of Human Papilloma Virus (HPV) with papillomas and squamous cell carcinomas of the sinonasal region. The present study was a hospital-based study conducted over a period of three years from May, 2014 to May, 2017 in the Department of Pathology, Government Medical College, Srinagar. A total of 19...

We report a case of primary umbilical endometriosis a rare clinical entity, with an incidence of 0.5–1% of all the patients of endometriosis. 1 Endometriosis as such is a common gynecological condition and pelvis being the most common site of the disease. Extra pelvic site is less common and even more difficult to diagnose due to the extreme variab...

Introduction: Scrape cytology is an important diagnostic tool. It has been used in many tissue types as an adjunct or replacement for frozen section/ intra operative consultation. Aim: This study was done to evaluate the role of scrape cytology in the diagnosis of thyroid lesions, its role as an adjunct to Fine Needle Aspiration Cytology (FNAC)...

Background The histological categorization of lymphoma has been a source of controversy for many years for both clinicians and pathologists. Clinicopathologic information of gastrointestinal lymphomas in Indian subcontinent is lacking. We studied histopathological spectrum of Primary Gastrointestinal Lymphomas (PGIL) and attempted to classify the G...

Portal biliopathy refers to cholangiographic abnormalities which occur in patients with portal cavernoma. These changes occur as a result of pressure on bile ducts from bridging tortuous paracholedochal, epicholedochal and cholecystic veins. Bile duct ischemia may occur due prolonged venous pressure effect or result from insufficient blood supply....

Hepatitis E virus (HEV), an RNA virus of the Hepeviridae family, has marked heterogeneity. While all five HEV genotypes can cause human infections, genotypes HEV-1 and -2 infect humans alone, genotypes HEV-3 and -4 primarily infect pigs, boars and deer, and genotype HEV-7 primarily infects dromedaries. The global distribution of HEV has distinct ep...

Hepatobiliary and pancreatic ascariasis (HPA) was described as a clinical entity from Kashmir, India in 1985. HPA is caused by invasion and migration of nematode, Ascaris lumbricoides , in to the biliary tract and pancreatic duct. Patients present with biliary colic, cholangitis, cholecystitis, hepatic abscesses and acute pancreatitis. Ascarides tr...

Abstract Hepatitis E was identified as an epidemic of non-A, non-B hepatitis from Kashmir, India in 1978. Hepatitis E virus (HEV), the etiological agent is the sole member of family Hepeviridae. The virus has marked heterogeneity and infects many animals like bats, camel, chicken, deer, boar, mongoose, pigs, rats, rabbit and cutthroat trout. Hepati...

Background: Renal clear cell carcinoma (RCC) accounts for about 3% of adult malignancies and about 90% of neoplasms of the kidney. It is most common in men aged 50 to 60 years old. RCC has different manifestations, including metastasis in uncommon sites and paraneoplastic syndromes. Aims: To evaluate the clinicopathological pattern of RCC. Material...

This is a PowerPoint presentation of a invited lecture delivered to UGC-Sponsored State Level Workshop-2016 under CPE Scheme on ”Analytical Laboratory Techniques: Applications and Future Prospects” convened by the Department of Chemistry, Islamia College of Science and Commerce, Hawal, Srinagar, Kashmir, J&K, India.

Laboratory tests are essential in disease evaluation, follow up and treatment; however, reproducibility of results is a major concern amongst patients. Times have changed. There were days when we visited Hakeem-Sahib who on first look told about illness/suffering and prescribed a detailed advice on food and ordered a decoction of an herb for a drin...

A retrospective study was conducted at SKIMS Medical College, Bemina from February 2012 to March 2016 where about 70 patients (children) of acute small gut obstruction were studied. The aim of this study was to find the commonest cause of obstruction in our population, study; age, sex and demographic distribution as per aetiology, and morbidity and...

Objectives: Abnormal Uterine Bleeding (AUB) is considered one of the most common and challenging problems presenting to the gynaecologist, regardless of the age the women .The present study was done with the aim of studying the histopathological pattern of the endometrium in women of various age groups presenting with abnormal uterine bleeding. Met...

SUMMARY. Hepatitis E is a systemic disease affecting the liver predominantly and caused by infection with the hepatitis E virus (HEV). HEV has marked genetic heterogeneity and is known to infect several animal species including pigs, boar, deer, mongoose, rabbit, camel, chicken, rats, ferret, bats and cutthroat trout. HEV is the sole member of the...

Point-of-care tests provide a plausible diagnostic strategy for hepatitis C infection in economically impoverished areas. However, their utility depends upon the overall performance of individual tests. A literature search was conducted using the metasearch engine Mettā, a query interface for retrieving articles from five leading medical databases....

Aims: The role of biliary ascariasis in etiology of recurrent pyogenic cholangitis in endemic areas has not been well studied. Methods: We studied 30 patients of recurrent pyogenic cholangitis with brown pigment stones and 30 patients with cholesterol gallstones. Stones from 22 patients (11 brown pigment stones and 11 gallstones) were examined by i...

Gastric neuroendocrine carcinoma is a rare tumor which has a poor prognosis. Herein, we present a 55-year-old woman who presented with complaints of recurrent vomiting, hematemesis and weight loss. Endoscopic examination showed a large ulcerated mass in the antrum. Microscopic evaluation of the specimen taken through biopsy was compatible with a sm...

We did a retrospective study to compare the postoperative results of patients after stapler haemorrhoidectomy and conventional haemorrhoidectomy (Milligan Morgan Technique) This retrospective study was conducted SKIMS Medical College Bemina from November 2006 to January 2010 where about 40 patients of MIPH were studied and compared with same number...

Background/objective Rapid point-of-care tests provide plausible diagnostic strategy for hepatitis B surface antigen (HBsAg) in low resource areas. However, their utility depends upon their overall performance. Our objective was to meta-analyze the diagnostic accuracy of rapid point-of-care tests for HBsAg. Methods Literature search was done with...

Strongyloidiasis is infection caused by the nematode Strongyloides stercoralis. Chronic uncomplicated strongyloidiasis is known to occur in immunocompetent individuals while hyperinfection and dissemination occurs in selective immunosuppressed hosts particularly those on corticosteroid therapy. We report two cases of hyperinfection strongyloidiasis...

Hodgkin's lymphoma complicating chronic ulcerative colitis is extremely rare. We report a case of extranodal Hodgkin's lymphoma involving rectosigmoid in a patient of chronic ulcerative colitis on long-term azathioprine. A 67-year-old man presented with extensive ulcerative colitis, on follow-up since September 2005. He received long-term steroids,...

The purpose of the present study was to evaluate the diagnostic accuracy of rapid point-of-care tests for Hepatitis C. For this we proposed to conduct a systematic review and meta-analysis on studies which evaluated accuracy of rapid diagnostic tests (RDTs) and point-of-care tests (POCTs) for Hepatitis C.

Nodular lymphoid hyperplasia of gastrointestinal tract is a rare disorder, often associated with immunodeficiency syndromes. There are no published reports of its association with Helicobacter pylori infection. From March 2005 till February 2010, we prospectively followed all patients with diffuse duodenal nodular lymphoid hyperplasia (DDNLH). Pati...

The American Journal of Gastroenterology is published by Nature Publishing Group (NPG) on behalf of the American College of Gastroenterology (ACG). Ranked the #1 clinical journal covering gastroenterology and hepatology*, The American Journal of Gastroenterology (AJG) provides practical and professional support for clinicians dealing with the gastr...

Large-scale waterborne epidemics of hepatitis E occur in developing countries. It is not known why these epidemics occur repeatedly and selectively in adult population? We studied seroepidemiology of an outbreak of hepatitis E in one of 15 villages that had recorded first epidemic of hepatitis E 30 years back. Another village not affected by the se...

[This corrects the article DOI: 10.1007/s12072-009-9159-5.].

There are limited data on response and long-term follow-up of octreotide therapy in type-I gastric neuroendocrine tumors. The objective of the present study was to assess the response of type-I gastric neuroendocrine tumors to octreotide-long acting, repeatable (LAR) therapy and evaluate long-term follow up of such patients after therapy. Three pat...

Context: Tropical calcific pancreatitis is unique to developing countries with of unknown origin. Objective: We evaluated the pattern of pancreaticobiliary ductal union in patients with tropical calcific pancreatitis. Patients: Twenty-one patients with tropical calcific pancreatitis were compared to 174 control subjects with no pancreaticobili...

There are few published reports of Trichuris dysentery syndrome (TDS) in children. The disease has not been reported in adults. To report the clinical, colonoscopic, and histologic findings of TDS in adults in an endemic area. Case series. Tertiary gastroenterology center. Eighty-four consecutive adult patients with chronic iron deficiency anemia o...

Hepatitis E is an emerging infectious disease. This review will focus on recent advances in the zoonotic transmission, global distribution and control of hepatitis E. Hepatitis E virus infection is known to cause waterborne epidemics and sporadic infections in developing countries. Recently, there have been several reports on zoonotic foodborne aut...

Medical therapy is an attractive adjuvant to endoscopic treatment in upper gastrointestinal (UGI) bleeding. This review aims to assess the treatment effects of proton pump inhibitor (PPI) therapy in acute non-variceal UGI bleeding. Outcome measures evaluated were further bleeding, surgery, all-cause deaths, ulcer deaths and non-ulcer deaths. We sea...

Guidelines for treatment of patients infected with hepatitis C virus genotype 4 are not available. To perform a meta-analysis of randomized controlled trials comparing peginterferon plus ribavirin with interferon plus ribavirin treatment in treatment-naive patients infected with chronic hepatitis C virus genotype 4. The outcome measure was sustaine...

Molecular adsorbent recirculating system (MARS) is an important option for patients with liver failure to give them additional time for recovery or to serve as a "bridge" to transplantation. However, its effect on survival for such patients is not well known. Our aim was to assess the treatment effects of MARS on patients with acute and acute-on-ch...