Mehmet murat Uzel

• MD
• Medical Doctor at Balıkesir University

This study aimed to automatically detect epiretinal membranes (ERM) in various OCT-scans of the central and paracentral macula region and classify them by size using deep-neural-networks (DNNs). To this end, 11,061 OCT-images were included and graded according to the presence of an ERM and its size (small 100–1000 µm, large > 1000 µm). The data set...

Background: This study aims to assess pediatric patients with Open Globe Injury (OGI) using the Modified Pediatric Ocular Trauma Score (MPOTS) and to investigate the correlation between Neutrophil-to-Lymphocyte ratio (NLR) and Platelet-to-Lympho-cyte ratio (PLR) parameters with the prognosis determined by MPOTS. Methods: In this retrospective st...

Aim: To characterize the patient groups referred to the ophthalmology clinic from the pediatrics clinic and to determine the frequency of the findings. Material and Method: The patients consulted to Balıkesir University Eye Clinic by the Pediatrics Clinic were evaluated retrospectively. Patients were divided into rule-out and ocular symptom groups....

Purpose: To automatically detect epiretinal membranes (ERM) in various OCT scans of the central and paracentral macula region and classify them by size using deep neural networks (DNNs). Methods: 11,061 OCT-images of 624 volume OCT scans (624 eyes of 461 patients) were included and graded according to the presence of an ERM and its size (small 100-...

Purpose To analyse the clinical and morphological characteristics of eyes with idiopathic epiretinal membrane (iERM) and foveal herniation (FH). Methods Clinical findings and OCT features of patients with iERM and FH were retrospectively analysed. Primary outcome were changes of the best-corrected-visual-acuity (BCVA) and OCT features from baselin...

Aside from general body fluid fluctuation, hemodialysis (HD) may cause changes in ocular fluid balance, resulting in changes in subfoveal choroidal thickness (SFCT) and other ocular parameters. As a result, the purpose of this study was to investigate the effects of hemodialysis on the reproducibility of SFCT measured by spectral domain-optical coh...

Clinical relevance Knowledge of work-related eye trauma in the construction and manufacturing industries will facilitate planning of policies and practices to protect against such occurrences. Background The aim of this study was to compare demographic, epidemiological, and clinical characteristics of work-related eye trauma in workers in the cons...

Purpose To determine the prognostic characteristics of optical coherence tomography (OCT) parameters by evaluating diabetic macular edema (DME) patients with early dexamethasone (DEX) shift after three doses of intravitreal ranibizumab (RNB) injection. Methods Fifty-four eyes of 34 patients who had DEX implant after three doses of RNB were include...

Purpose To investigate the effects of hemodialysis (HD) on the reproducibility of subfoveal choroidal thickness (SFCT) as measured by spectral domain-optical coherence tomography (SD-OCT) Methods In this study, 26 HD (26 eyes) patients had their pre- and post-HD SFCT measured, and the results were compared for reproducibility. Following a thorough...

INTRODUCTION: To assess demographic characteristics in patients with ocular Behçet's disease who use off-label drugs in Turkey. METHODS: The applications for off-label drug use (infliximab, adalimumab, mycophenolat mofetil) from hospitals in Turkey to the Turkish Medicines and Medical Devices Agency from January to December 2013 were evaluated retr...

ABSTRACT Purpose: To investigate the usefulness of systemic inflammatory markers [i.e., white blood cell and platelet counts, mean platelet volume, and their ratios] as diagnostic markers of the pathogenesis of diabetic macular edema. Methods: The study cohort included 80 diabetic macular edema patients (40 with diabetic retinopathy and 40 without)...

Mikrosferofaki, lens zonüllerinin hatalı gelişimi sonucu görülen, nadir bir konjenital anomalidir. Lensin şekil olarak sferik ve instabil hatta çoğu zaman sublukse olması görme azlığı ve pupiller bloğa yol açmaktadır. Antiglokomatöz medikasyon, lense yönelik cerrahi, lazer ve glokom cerrahileri dahil tüm tedavi alternatifleri düşünüldüğünde bunları...

Katarakt, tedavi edilebilir körlüğün en önemli nedenlerinden biridir. Günümüzde henüz katarakt gelişimini engelleyecek ve lenste oluşan kesafeti ortadan kaldıracak tıbbi tedavi yöntemi mevcut değildir. Opaklaşmış lensin çıkarılması amacıyla tarihsel süreçte farklı yaklaşımlar denenmiş olsa da günümüzde katarakt ekstraksiyonunda standart yöntem fako...

Purpose: To investigate of the refractive situations of healthy Central Anatolian population by separated groups in terms of different education level, in various age, gender, residence, and working status. Materials and Methods: The past general policlinic records between January 2015 and April 2015 was investigated retrospectively. The over 10-ye...

ÖZET: Subkonjonktival Hemorajide Ambulatuvar Kan Basıncı Ölçümünün Önemi Erdoğan YAŞAR*, Mehmet Murat UZEL*, Hakan ÇAKMAK**, Uğur GÜRLEVİK*** Ayşe Güzin TAŞLIPINAR UZEL**** Amaç: Subkonjonktival hemoraji hastalarında ambulatuvar kan basıncı ölçümü ile hipertansiyon açısından detaylı araştırma yapmak. Gereç ve Yöntem: Diğer etyolojik faktörleri ekar...

Purpose To investigate the effect of topical pilocarpine on topical cycloplegia and on the results of refractive surgery. Methods The study included 100 eyes of 100 patients who underwent laser-assisted in situ keratomileusis. Group 1 comprised patients who wanted to undergo surgery on the same day after cycloplegic examination and were applied wi...

Purpose To compare the efficacy of Samfilcon A and Lotrafilcon B bandage contact lenses after photorefractive keratectomy (PRK). Methods In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surgery and on postoperative days 1, 2 and 3. Slit bio...

Purpose To assess the impact of symptom duration on the recurrence of rhegmatogenous retinal detachment (RRD) and to determine the threshold symptom duration for recurrence. Patient and methods In this non-comparative, observational case series, a retrospective evaluation was made of the records of patients with RRD at baseline and during the post...

INTRODUCTION[|]The aim of this study was to define the optimal cutoff value of the neutrophil/lymphocyte ratio (NLR) to predict severe grades of diabetic retinopathy (DR). [¤]METHODS[|]A total of 40 patients with proliferative DR (PDR) and 40 patients with severe non-proliferative DR (NPDR) were included this prospective, case control study, and 35...

This study was conducted to reveal the role of systemic low-grade inflammation by calculating the Neutrophil/Lymphocyte Ratio (NLR) in Vitreomacular Traction Syndrome (VMTS) of different etiologies. A retrospective examination was made of the medical records at a tertiary referral hospital. The study included 31 patients with diabetic VMTS, 27 pati...

Purpose To report an unusual appearance on Spectralis optical coherence tomography (OCT) finding: bilateral adult-onset foveomacular vitelliform dystrophy (AFVD) concomitant with diabetic cystoid macular edema. Case Description Fundus examination of a 55 year-old patient demonstrated a round, elevated yellowish lesion centered by a pigmented spot,...

Optic disk pit, one of the optic disk cavitary anomalies, is generally congenital and unilateral and occurs equally in males and females. Optic disk pit maculopathy is characterized by intraretinal and subretinal fluid at the macula, causing visual deterioration. The origin of the macular fluid and the mechanism of transition to the subretinal spac...

Objectives Our aim was to compare the refractive status and anterior segment parameters of patients with juvenile open-angle glaucoma (JOAG) and normal subjects. Materials and Methods Twenty-five recently diagnosed cases of JOAG and 24 normal subjects were included in this prospective controlled clinical trial. Central corneal thickness (CCT), ant...

Purpose: To evaluate the effect of accelerated corneal crosslinking on corneal biomechanics with an ocular response analyzer in patients with progressive keratoconus. Methods: In this retrospective study, 50 eyes of 45 patients with progressive keratoconus who underwent accelerated corneal crosslinking were evaluated with ocular response analyze...

Purpose: To investigate the effect of Helicobacter pylori (H. pylori) infection on choroidal thickness (CT) and retinal nerve fiber layer thickness (RNFLT). Methods: The study included 25 patients with H. pylori infection and 25 healthy individuals as the control group. Helicobacter pylori patients were classified as the pre-treatment (Group 1;...

Sildenafil is one of the most commonly used drugs for sexual dysfunction or to increase libido, and it regulates endothelial nitric oxide synthase enzyme via selective phosphodiesterase-V inhibition. Sildenafil can be easily obtained without a medical indication or prescription yet it is not considered as a completely safe medication. Hemoptysis an...

Purpose: We aimed to investigate the effect of trabeculectomy on serum brain-derived neurotrophic factor (BDNF) levels. Our secondary goal was to compare serum and aqueous humor (AH) BDNF levels in primary open-angle glaucoma (POAG) and control subjects. Methods: This prospective, cross-sectional study consists of 20 eyes of with advanced-stage...

Objectives: To investigate the postoperative changes in the anterior segment parameters by Scheimpflug imaging method in patients undergoing trabeculectomy surgery. Methods: This prospective study included 38 phakic eyes of 38 patients with primary open-angle glaucoma who underwent trabeculectomy. Anterior chamber angle (ACA), anterior chamber d...

Purpose: To assess the effect of posterior capsular opacification (PCO) and Neodymium-doped:Yttrium Aluminium Garnet (Nd:YAG) laser capsulotomy on tilt and decentration of intraocular lens (IOL) at vertical and horizontal meridians. Methods: The study included 64 eyes of 64 patients. IOL decentration and tilt were measured using a Scheimpflug camer...

Purpose: To investigate the corneal densitometry in subclinical keratoconus with normal elevation and pachymetric parameters. Methods: Patients with clinical keratoconus in one eye and subclinical keratoconus in the fellow eye were identified. The study group was selected from patients with subclinical keratoconus who showed normal results from...

Purpose: To evaluate the anterior segment biometric parameters of non-accommodative and accommodative refractive accommodative esotropia (RAE). Methods: Eighty-one eyes of 81 patients were included in this prospective, case-control study. The patients were divided into three groups as follows: the RAE group (n = 31), the hypermetropia group (n =...

Purpose: To assess the decentration and angle of tilt of the intraocular lens (IOL) according to the intravitreal tamponade types used in combined phacoemulsification and vitreoretinal surgery. Methods: This prospective and randomized clinical study involved 73 eyes of 69 patients who underwent combined vitreoretinal surgery. Eyes with intravitr...

Purpose: To assess the compliance with contact lens (CL) use among ophthalmologists and other health professionals, and to identify the main noncompliant behaviors. Methods: A cross-sectional, comparative study was designed for soft CL wearers. Twenty-five ophthalmologists, 24 medical doctors other than ophthalmologists, 20 nurses (health profes...

Purpose: To assess the decentration and tilt of one-piece foldable acrylic intraocular lens following two different intraocular lens implantation techniques. Methods: This prospective, randomized clinical study conducted on 102 eyes of 91 patients who underwent cataract surgery between September 2015 and May 2016 at Ulucanlar Eye Training and Resea...

PurposeThis was a collaborative study from the Ophthalmology and Gastroenterology departments of a tertiary care hospital, designed to investigate the local ocular surface parameters in patients with celiac disease (CD).Methods Fifty-six eyes of 28 patients with CD and 58 eyes of 29 healthy adult subjects serving as controls were evaluated. The Sch...

Purpose: To evaluate the effect of pterygium and pterygium surgery on corneal biomechanics by ocular response analyzer (ORA, Reichert, USA). Methods: This study considered 68 eyes (from 34 patients with a mean age of 21.2±7.1 years) with unilateral nasal, primary pterygium (horizontal length <4 mm), and having undergone pterygium excision and co...

Aim: To evaluate changes in the coordinates of the line of sight (LoS) and higher order aberrations (HOAs) of eyes with keratoconus, following corneal cross-linking (CXL). Methods: All patients (93 eyes) underwent detailed ophthalmologic examination and Pentacam HR measurements at baseline and at 3, 6, and 12 months after corneal CXL. LoS coordi...

Purpose: To evaluate the impact of preoperative central foveal thickness (CFT) on visual acuity after surgery in patients with idiopathic vitreomacular traction and to calculate a cut-off value in preoperative CFT. Methods: Thirty-five patients with idiopathic vitreomacular traction were evaluated retrospectively. A complete ophthalmological exa...

Aim: To evaluate the results of accelerated (9 mW/cm2) corneal crosslinking (CXL) in progressive keratoconus according to age group. Methods: Patients undergoing accelerated corneal CXL with hypo-osmolar riboflavin solution were included in the study. The patients were divided into two groups: Group 1 (<18 years, 41 eyes of 37 patients) and Group...

Purpose To evaluate the thickness of the peripapillary retinal nerve fiber layer (RNFL), total macula, macular ganglion cell layer (GCL), inner plexiform layer (IPL), and choroid in pediatric migraine patients and compare the values with healthy subjects. Methods This observational and cross-sectional study included 40 patients in the migraine gro...

Purpose To evaluate the effects of pterygium on biometry measurements and the relationship between these effects and pterygium size. Setting Ulucanlar Eye Hospital, Ankara, Turkey. Design Prospective comparative study. Methods Patients who had unilateral primary pterygium excision were included in the study group. Anterior segment photographed i...

Background and objective: To evaluate the effect of preoperative intravitreal bevacizumab (IVB) (Avastin; Genentech, South San Francisco, CA) injection on the choice of endotamponade at the end of surgery in patients who underwent pars plana vitrectomy (PPV) for diabetic tractional retinal detachment (DTRD). Patients and methods: Seventy-eight p...

Purpose: To evaluate the preoperative characteristics that might influence corneal flattening, visual acuity, and corneal haze after accelerated (9 mW/cm2) corneal collagen crosslinking (CXL). Setting: Ulucanlar Eye Hospital, Ankara, Turkey. Design: Retrospective case series. Methods: Accelerated corneal CXL was performed in eyes with progre...

Purpose To compare the anterior segment parameters of patients with juvenile diabetes mellitus (DM) and healthy children by optical biometry. Methods This prospective controlled clinical trial included 47 patients with juvenile type 1 DM and 50 age- and sex-matched healthy children. Central corneal thickness (CCT), aqueous depth (AD), lens thickne...

Purpose: The aim of this study was to evaluate the early term topographic and aberration results of accelerated (9 mW/cm) corneal cross-linking (CXL) treatment in keratoconic thin corneas. Methods: Forty-nine eyes from 43 patients (mean age of 21.2 ± 7.1) with progressive keratoconic thin corneas (<400 μm without epithelium) who had accelerated...

Cataract is the one of the major causes of treatable blindness. Nowadays, there is no medical treatment method to prevent the development of cataracts and eliminate the opacification in the lens. In the historical process, different approaches for removing the opacified lens have been tried. The standard method of cataract extraction today is phaco...

Purpose: To evaluate the effect of accelerated corneal cross-linking (CXL) according to corneal thickness in keratoconus. Methods: Patients undergoing corneal CXL (9 mW/cm) with hypo-osmolar riboflavin solution were included in this study. The patients were divided into 2 groups. Group 1 included patients with corneal thickness below 400 μm (50...

Purpose: To report phacoemulsification surgery in a case of colobomatous macrophtalmos with microcornea syndrome. Case report: A 72-year-old male presented with complaints of low vision was evaluated. Biomicroscopic examination of anterior segment revealed cataract and microcornea for both eyes and the finding of microcornea was confirmed by Pentec...

Terson Syndrome occurring after intracranial hemorrhage, has an important place in the posterior segment hemorrhages not associated with diabetes and ocular trauma. In adults, traumatic intracranial hemorrhage, neurological symptoms and high mortality risk are known to be closely associated with Terson Syndrome. In addition, case reports and clinic...