Mehmet Tonge

Mehmet Tonge
  • MD, MS (Neurosurgeon)
  • Professor (Associate) at Istanbul Medipol University

About

31
Publications
13,074
Reads
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274
Citations
Current institution
Istanbul Medipol University
Current position
  • Professor (Associate)
Additional affiliations
October 2018 - present
Istanbul Medipol University
Position
  • Staff Neurosurgeon
February 2017 - October 2018
Group Florence Nightingale Hastaneleri
Position
  • Staff Neurosurgeon
December 2014 - October 2018
Memorial Health Group
Position
  • Staff Neurosurgeon

Publications

Publications (31)
Article
Aim: To evaluate the supraorbital and transorbital approaches as alternative entry sites and trajectories targeting the nucleus accumbens (NAc), subcallosal cingulate gyrus (SCG), and lateral hypothalamic area (LHA), in cadavers and surgical planning station. Material and methods: The three-dimensional relationship of the identified trajectories...
Article
Full-text available
Amaç: Derin beyin stimülasyonu, son yıllarda giderek artan kullanım alanına erişmekte ve artan sayıda bilimsel çalışmaya konu olmaktadır. Çalışmamızda, 2000-2021 yılları arasında bu alanda yapılmış bilimsel çalışmaların detaylı bir analizi gerçekleştirilmiştir. Gereç ve Yöntem: CiteSpace 5.8.R3 programı kullanılarak "Web of Science" veri tabanında...
Article
Full-text available
Introduction: The algorithms used in the GammaPlan treatment planning system are “Tissue Maximum Ratio (TMR) classi- cal,”“TMR 10,” and “convolution” algorithms, respectively. In this study, the consistency of dosimetric measurements with the TMR 10 protocol used in SRC (stereotactic radiosurgery) planning in lesions located in homogeneous and inho...
Article
Background We assessed the safety and efficacy of flow diverter stents (FDSs) in the treatment of recanalized or residual intracranial aneurysms treated endovascularly. Materials & Methods Patients whose recanalized or residual aneurysms were treated with FDSs in five tertiary hospitals were reviewed retrospectively. The patients’ demographic data...
Article
Full-text available
Objective Despite optimal improvement in motor functioning, both short- and long-term studies have reported small but consistent changes in cognitive functioning following STN-DBS in Parkinson’s disease (PD). The aim of the present study was to explore whether surgical characteristics were associated with cognitive decline one year following STN-DB...
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Full-text available
Aim: One of the most distressing hardware-related complications of deep brain stimulation is an infection. These infections can be either treated with antibiotics or with removal of the infected hardware followed by reimplantation. In our experience the success of antibiotic therapy was about 50%. Here, we have investigated the costs of treating t...
Chapter
Psychiatric disorders are among the leading causes of severe and long-term disability worldwide, decreasing the quality of life of individuals and families. Moreover, they induce an enormous economic burden on societies. Current treatment modalities for patients with psychiatric disorders include drug therapy and/or psychotherapy. However, these tr...
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Background/aim: This study was undertaken to evaluate the effects of positive end-expiratory pressure (PEEP) levels on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) and to determine the appropriate PEEP level during steep Trendelenburg position combined with pneumoperitoneum.Materials and methods: Ten pigs were included in this...
Article
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Objectives: Deep brain stimulation is nowadays a frequently performed surgery in patients with movement disorders, intractable epilepsy, and severe psychiatric disorders. The most feared complication of this surgery is an intracerebral hemorrhage due to the electrode placement, either for intraoperative electrophysiology (microelectrode recording)...
Article
Full-text available
Aim: Failed cranioplasty attempts may lead to numerous complications in a broad spectrum including cosmetic problems, infection, neurological deterioration and even death. Selection of the most appropriate surgical technique for second and further surgical attempts for these patients still remains a debate. We aimed to share our experience and tec...
Article
Cranial vault reconstruction in the pediatric population is a specialized procedure, which requires additional considerations. Generally, inherent difficulties of bone storage and cranioplasty are neglected in the literature. We present a simple method of bone storage and autologous cranioplasty in a small child with severe head injury. The child u...
Article
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Vertebral artery injury including thrombosis, arteriovenous fistula (AVF), pseudo-aneurysm and hemorrhage may be iatrogenic or due to penetrating or blunt trauma. Although mostly asymptomatic, vertebral artery injury may also present with vertebrobasilar insufficiency findings, cephalgia, radicular pain or myelopathy due to blockade of arterial flo...
Article
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Aim: High frequency stimulation of the subthalamic nucleus (STN) is nowadays a widely performed surgery for patients with Parkinson's disease (PD). The field has witnessed a shift from indirect targeting to direct targeting. The question arises whether this change has influenced the final electrode position in STN deep brain stimulation surgery. T...
Article
Full-text available
In the treatment of epilepsy, encouraging results have been achieved with surgical treatment, especially for temporal lobe epilepsy (TLE). Drug resistance must be diagnosed as early as possible, because the ensuing seizures can be eliminated surgically via temporal lobe surgery in a high percentage (70%-90%) of patients. In this study we share our...
Article
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This study was undertaken in the belief that the atypical antipsychotic drug quetiapine could prevent apoptosis in the penumbra region following ischemia, taking into account findings that show 5-hydroxytryptamine-2 receptor blockers can prevent apoptosis. We created 5 groups, each containing 6 animals. Nothing was done on the K-I group used for co...
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Various complications following ventriculoperitoneal (VP) shunting have been reported but transoral protrusion of peritoneal catheter is a very rare situation. This case is the first adult with a transoral VP shunt protrusion in available literature. A 47-year-old female with pseudotumor cerebri admitted after the peritoneal catheter protruded from...
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Aim: In this paper we discuss the Neurosurgical Training Programme (NTP) in some European countries. Material and methods: Although there is no official data on how many neurosurgeons are certified in Europe, our calculation shows that this number is somewhat lower than in the United States of America and even 3 times lower than in Japan (per 10...
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Cerebro-spinal fluid (CSF) leakage caused by defects on the dura mater after trauma or some neurosurgical interventions is an important issue. In this study, we investigated the effects of local and systemic use of phenytoin sodium on dural healing. MATERIAL and Thirty-six male Wistar rats were divided into control, local phenytoin and systemic phe...
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Topical hemostatic agents are widely used in brain surgery but they have some disadvantages such as foreign body reaction, being a focus for infection and causing artifacts in radiological examinations. The purpose of this study is to compare the effectiveness and safety of microporous polysaccharide hemospheres (MPH) with a well known agent, oxidi...
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Radical oxygen species produced after injury counteracts antioxidant activity and frequently causes severe oxidative stress for the tissues. Alpha-lipoic acid is a powerful metabolic antioxidant with immunomodulatory effects which provides neuroprotection. The aim of this study is to investigate the neuroprotective and anti-apoptotic effects of alp...
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A 56-year-old female presented with two intracranial meningiomas with different grades manifesting as speech disorder for one week. Neurological and radiological evaluations showed two distinct tumors suggestive of multicentric meningiomas. Surgical resection of both masses was performed in the same procedure. Histological examination found both me...
Article
Full-text available
The main purpose of this report is to demonstrate the effects of fractionated radiosurgery regimens in the management of optic gliomas MATERIALS and Two patients suffering from progressive loss of vision due to optic nerve gliomas were treated with Gamma Knife radiosurgery in three fractions within three consecutive days instead of a single dose re...
Article
Full-text available
llar region. Pituitary adenomas and craniopharyngiomas have different symptomato- logies, anatomical features and natural histories. Microneurosurgical interventions, radiotherapy and medical treatment are generally insufficient in the treatment of both these pathologies. Most recently, stereotactic radiosurgery is an important, safety and effectiv...

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