Mehdi Asgari Siahboumi

Mobarakeh Steel Company · civil design

Patients with autoimmune bullous diseases are at an increased risk of infection, both from the underlying skin disease and from immunosuppressive treatments. Limited information is available on vaccine beliefs and behaviors in dermatology patients and adults with autoimmune bullous diseases in particular. To understand vaccine decision making, iden...

Having a chronic disease is one of the most consistent factors associated with vaccine uptake for adults in the general population, but vaccination beliefs and behaviors specific to those with chronic skin diseases have not been explored. The objective of this study was to explore factors associated with vaccine uptake and barriers to vaccination i...

Background Actinic keratoses (AK) are rough scaly patches that arise on chronically ultraviolet (UV)-exposed skin and can progress to keratinocyte carcinoma. Treatment options for AK include topical medications, photodynamic therapy (PDT), cryosurgery, and laser ablation. Objective This executive summary provides a synopsis of the 18 evidence-base...

Background Actinic keratoses (AK) are rough scaly patches that arise on chronically ultraviolet-exposed skin and can progress to keratinocyte carcinoma. Objective This analysis examined the literature related to the management of AK to provide evidence-based recommendations for treatment. Grading, histologic classification, natural history, risk o...

One of the newest advancements in manufacturing and project management is Building Information Modeling (BIM) which uses creative processes for production, analysis, and management of building information. On the other hand, the output of the Geographic Information System (GIS) model includes one or more actual locations, which satisfy all needs. I...

The incidence of basal cell carcinoma (BCC) is higher among men than women. Susceptibility loci for BCC have been identified through genome-wide association studies (GWAS), and two previous studies have found polygenic risk scores (PRS) to be significantly associated with risk of BCC. However, to our knowledge, sex-stratified PRS analyses examining...

Xeroderma pigmentosum (XP) is an autosomal recessive disorder of nucleotide excision repair, characterized by hypersensitivity to ultraviolet light (UV) radiation.1‐3 In individuals with XP, the incidence of non‐melanoma skin cancers prior to the age of 20 years is approximately 10,000 times that seen in the general population.⁴ The most common cau...

Although previous studies have explored racial/ethnic differences in incident atopic dermatitis (AD) in childhood, few studies have examined risk factors associated with AD persistence. As such, we sought to examine differences in incidence and persistence of childhood AD by race/ethnicity accounting for sociodemographic characteristics and perinat...

Genetic factors play an important role in cutaneous squamous cell carcinoma (cSCC) risk. Genome-wide association studies have identified 21 single nucleotide polymorphisms (SNPs) associated with cSCC risk. Yet no studies have attempted to quantify the contribution of heritability to cSCC risk by calculating the population attributable risk (PAR) us...

Linked Articles: Madeleine et al. Br J Dermatol 2017; 177:1208–1216.

Although tremendous progress has been made in recent years in skin cancer care for organ transplant recipients, significant gaps remain in data-driven clinical guidelines, particularly for the treatment and prevention of cutaneous squamous cell carcinoma (cSCC), the most common malignancy among this population. In this review, we aim to summarize c...

Linked Article: Wei et al. Br J Dermatol 2017; 177:1066–1073.

Introduction: Regulatory agencies, including the U.S. Food and Drug Administration, are considering policies to ban indoor tanning for youth aged <18 years. Using data from a nationally representative sample, this study assessed parental support for age-based bans as well as less restrictive parental permission requirements. Methods: Data came f...

Actinic keratoses (AKs) are precancerous skin lesions afflicting nearly 58 million people in the United States per year and costing over a billion dollars annually to treat.¹,2 Two of the most widely used topical field-based treatments for AKs are fluorouracil and imiquimod.³ Although variations exist in how these topical medications are prescribed...

Large population-based studies are useful for determining cancer outcomes, but interpreting their findings requires understanding their limitations. Youlden et al. highlight the utility of using a large dataset for studying melanoma survival, whereas Gimotty et al. point out the limitations of such datasets in miscoding thickness, a key prognostic...

In this study, production of ⁴⁷Sc radionuclide by irradiating the natural titanium dioxide powder (TiO2) in the fast neutron flux (~ 4.5×10¹¹ n·cm⁻²·s⁻¹) for 4 days in Tehran Research Reactor (TRR, Iran) and separation from titanium target was investigated. The study showed the feasibility of production ⁴⁷Sc by TRR. The separation efficiency and ra...

In 2014, Medicare expenditures increased 12%, the largest increase reported since 2002, resulting in major concerns by both patients and physicians. Although costs are rising for both specialty drugs and generic medications,out-of-pocket costs, restrictive formularies,and health plan bureaucracies are limiting patients' access to necessary medicati...

Traumatic coronary artery-cameral fistulas (TCAF) are rare and may present secondary to penetrating injuries (80%) or iatrogenic traumas. Early operative intervention remains the recommended treatment modality for accidental traumatic coronary artery fistulas. We report the case of a 17-year-old man who presented with left anterior descending coron...

BACKGROUND: Primary actinomycosis of the breast is a rare disease which may present as sinus tract or with mass-like features mimicking malignancy. Clinical presentation makes it difficult to distinguish primary actinomycosis from mastitis and inflammatory carcinoma. CASE REPORT: A 48-year-old woman presented with a mass in the left breast of 2 mon...