Meghan Vinograd

Meghan Vinograd
VA San Diego Healthcare System | VASDHS · Center of Excellence for Stress and Mental Health

PhD Clinical Psychology

About

27
Publications
3,523
Reads
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55
Citations
Introduction
I investigate the the neural, immunological and cognitive mechanisms underlying the relationship between adversity and psychiatric symptomatology.
Additional affiliations
January 2017 - present
University of California, Los Angeles
Position
  • Research Assistant
February 2014 - July 2014
VA Palo Alto Health Care System
Position
  • WOC Research Assistant
Description
  • Observed and administered neuropsychological test batteries with Veteran and control participants, assisted with implementation of fMRI brain scan paradigm for new study
July 2011 - July 2014
Stanford University
Position
  • Research Assistant
Description
  • Conducted structured and semi-structured clinical interviews (SCID and KSADS), ran fMRI brain scan sessions, conducted psychophysiology-based sessions, developed session and training protocols, trained fellow coordinators and research assistants
Education
September 2014 - July 2020
University of California, Los Angeles
Field of study
  • Clinical Psychology
September 2014 - December 2015
University of California, Los Angeles
Field of study
  • Clinical Psychology
September 2007 - June 2011
Stanford University
Field of study
  • Psychology

Publications

Publications (27)
Article
Background Elevated defensive responding, through startle reflex (SR) and skin conductance response (SCR), may contribute to onset and maintenance of depression and anxiety. Most work examining SR and SCR has predicted psychiatric diagnoses. There is a paucity of research examining links between SR or SCR and dimensional measures of psychopathology...
Article
Prior research has struggled to differentiate cortisol stress response patterns reflective of well-regulated versus dysregulated hypothalamic–pituitary–adrenal (HPA) axis function among adolescents. Here, we show how exploring profiles of joint HPA– inflammatory stress responsivity, and linking those profiles to pubertal development and peer stress...
Article
Full-text available
Background: Anhedonia, the reduction of pleasure and reward-seeking behaviour, is a transdiagnostic symptom with well-described neural circuit mediators. Although typically observed during disease state, extant hypotheses suggest that anhedonia may also be an early risk factor for development of psychopathology. Understanding the contribution of a...
Article
Altered functioning of the brain’s threat and reward circuitry has been linked to early life adversity and to symptoms of anxiety and depression. To date, however, these relationships have been studied in isolation and in categorical-based approaches. It is unclear to what extent early life adversity and psychopathology have unique effects on brain...
Chapter
Anhedonia, the reduction of pleasure and reward-seeking behavior, is a transdiagnostic construct associated with a range of important health outcomes. As with other psychiatric disorders, anhedonia is a relatively common, though understudied, feature of posttraumatic stress disorder (PTSD) that is not adequately targeted by existing treatments. The...
Article
Full-text available
Depression is a common, often recurrent disorder that causes substantial disease burden worldwide, and this is especially true for women following the pubertal transition. According to the Social Signal Transduction Theory of Depression, stressors involving social stress and rejection, which frequently precipitate major depressive episodes, induce...
Article
Full-text available
Dimensional models of anxiety and depression highlight common and distinct symptom clusters that are thought to reflect disruptions in underlying functional processes. The current study investigated how functioning of threat neurocircuitry relates to symptom dimensions of anxiety and depression. Participants were aged 18-19 years (n = 229, 158 fema...
Article
Neuroticism has been associated with depression and anxiety both cross-sectionally and longitudinally. Interpretive bias has been associated with depression and anxiety, primarily in cross-sectional and bias induction studies. The purpose of the current study was to examine the role of interpretive bias as a prospective risk factor and a mediator o...
Article
Full-text available
Depression is both prevalent and costly, and many individuals do not adequately respond to existing psychopharmacological and behavioral interventions. The current article describes the use of neuroscience in augmenting behavioral interventions for depression in two primary areas: anhedonia and cognitive deficits/biases. Neuroscience research has i...
Article
Full-text available
Sharing specific autobiographical events is likely to influence the support people give us; a person who shares little detail of their lives may be unlikely to attract social support and this may in turn contribute towards anxious and depressive symptoms. Participants (N = 142) reported memories evoked by negative and positive cue words and these m...
Poster
Full-text available
Background: Anxiety and depression are highly comorbid possibly because they share a common core of general distress or negative affect. Consistent with this viewpoint, Prenoveau and colleagues (2010) identified a broad general factor common to both anxiety and depression (general distress), two factors of intermediate breadth (anhedonia and fears)...
Poster
Full-text available
The present study examined the relation between early life adversity and working memory among young adults. We found that the number of overall major adversities significantly predicted impaired working memory for neutral stimuli, while the number of instances of abuse significantly predicted impaired working memory for negative stimuli.
Chapter
Full-text available
Chapter 5 describes the Research Domain Criteria (RDoC) framework as it pertains to emotion regulation, an in-progress research framework mapping psychological constructs onto discrete units of analysis (genes, molecules, cells, brain circuits, physiology, behavior, and self-report). It accommodates contemporary and developing emotion frameworks su...

Network

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Projects

Project (1)
Project
As the title suggests, in this project we're interested in exploring the social factors which lead to poor memory specificity and the social consequences of it too. In particular, we're examining whether poor specificity may be a communication style that is learnt over time through operant conditioning (e.g., if we're punished for sharing lots of details of our autobiographical past we may learn to not share such details with other people). Also, we're exploring whether people who are more specific in the way that they talk about their past are typically supported by other people to greater extent (it's presumably easier to help someone with a problem if they're specific about what the problem is).