Meetul Kumar

Defence Research and Development Organisation | DRDO · Directorate of International Cooperation

With the rising inadequacy in arable land and water resources, the progress of agriculture sector is only possible by upsurging the resources use efficacy following least damage to agroecology via effective exploitation of modern technologies. Amid these, nanotechnology has the potential to revolutionize agricultural systems, biomedicine, environme...

Nanotechnology is a broad term used to portray technologies functioning on nanoscales for their exploitation in real-world applications. The release of metal nanoparticles, specifically silver nanoparticles (AgNPs), in the natural environment has raised concerns about their distinguished effects on living organisms, including plants. Recent studies...

The scientific and technological applications of one of the nanomaterials viz.; carbon dot (C-dots), having extraordinary properties, is becoming an emerging and ongoing research area in recent times. In the present study, we have evaluated the effectiveness of C-dots in reducing arsenic (As) toxicity by analyzing physiological, biochemical and mol...

Heavy metal/metalloid (HM) contamination issues are becoming progressively more widespread worldwide, which are witnessed in various locations like foundries, mining industries, smelters, vehicular emissions, coal burning power plants, and agricultural sectors. Heavy metal/metalloid occurs naturally in the Earth’s crust, but man-made sources and va...

Metal/metalloid (HM) toxicity/stress has become a worldwide menace due to the rising accretions in water, soil, and air which lead to detrimental effects in plants. The general consequences of HM toxicity include oxidative injury which causes polypeptide oxidation, lipid peroxidation, enzyme inactivation, DNA mutilation, and/or alteration of other...

Arsenic (As)-toxicity is recognized as one of the major environmental problems, affecting productivity of crops worldwide, thereby threatening sustainable agriculture and food security. Progression in nanotechnology and its impacts have brought up concerns about the application of engineered nanoparticles (NPs) in various sectors of the economy, in...

Arsenic (As)-toxicity is recognized as one of the major environmental problems, affecting productivity of crops worldwide, thereby threatening sustainable agriculture and food security. Progression in nanotechnology and its impacts have brought up concerns about the application of engineered nanoparticles (NPs) in various sectors of the economy, in...

This study reports the role of MAPKs (JNK, ERK, and p38), and activator protein‐1 (AP‐1) transcription factor in the hypobaric hypoxia induced change in lung tissue. Healthy male Sprague–Dawley rats were exposed to hypobaric hypoxia for 6, 12, 24, 48, 72, and 120 hr. Hypoxia resulted in significant increase in reactive oxygen species (ROS), vascula...

An optimized methodology of Agrobacterium -mediated stable genetic transformation of potato ( Solanum tuberosum L.) using the shoot organogenesis potential of internodal stem segments for increased resistance to bacterial plant pathogen, Ralstonia solanacearum L. was developed. Improvised plant regeneration protocol for expression of antimicrobial...

Interferon gamma (IFN-γ) is an important immunoregulatory cytokine that has a central role against viral and bacterial infections. In this study, the cDNA encoding 141 amino acids of mature IFN-γ from mice splenocytes was cloned in a prokaryotic expression vector pQE 30. Optimization of expression conditions resulted in high IFN-γ protein. Western...

The present study was undertaken to evaluate the diversity of Phytophthora infestans isolates collected between 1996 and 2006 from potato-growing regions of India. Thirty-two genotypes were distinguished among 70 isolates characterized using mating type, metalaxyl resistance, mitochondrial DNA (mtDNA) haplotypes and microsatellite markers. The mati...

Transgenic of Indian potato cultivar Kufri Badshah expressing synthetic, modified cry1Ab gene were developed against potato tuber moth (Phthorimaea opercullela Z.) a destructive pest. The cry1Ab gene was in spatial and temporal expression under the control of tuber-specific GBSSi promoter. The transformation vector pBinCG1 was developed harbouring...

The phylogenetic relationships of 36 locally grown Prunus armeniaca genotypes which are collected from nine sampling sites from two valleys viz. Nubra (9,600 ft) and Leh (11,500 ft) of trans-Himalayan region were analyzed using 31 PCR markers (20 RAPDs and 11 ISSRs). This is the first report of molecular genetic diversity studies in apricot from th...

Twelve apricot (Prunus armeniaca L.) genotypes were collected from two valleys viz., Nubra (9,600 ft) and Leh (11,500 ft) of trans-Himalayan region of Ladakh (Jammu & Kashmir). These genotypes were characterized using random decamer RAPD primers. Initially, 20 decamer primers were used to screen the 12 accessions of which 16 produced the reproducib...

In the present investigation four different explants from Tecomella undulata were used for in vitro adventitious shoot regeneration. The treatment having IAA (0.1 mg/l) and zeatin (2.5mg/l) in combination yielded maximum number of shoots from hypocotyle (16) and cotyledonary nodes (27). In case of epicotyle, the best response (11 shoots per explant...

The phylogenetic relationships of 13 Jatropha genotypes from different parts of the India were analysed using 34 polymerase chain reaction (PCR) markers (20 random amplified polymorphic DNAs (RAPDs) and 14 inter simple sequence repeats (ISSRs)). Amplification of genomic DNA of the 13 genotypes, using RAPD analysis, yielded 107 fragments that could...

The phylogenetic relationships of 13 Jatropha genotypes from different parts of the India were analysed using 34 polymerase chain reaction (PCR) markers (20 random amplified polymorphic DNAs (RAPDs) and 14 inter simple sequence repeats (ISSRs)). Amplification of genomic DNA of the 13 genotypes, using RAPD analysis, yielded 107 fragments that could...