Meenakshi Thakur- Ph.D.
- Professor (Assistant) at College of Horticulture and Forestry, Neri, Hamirpur
Meenakshi Thakur
- Ph.D.
- Professor (Assistant) at College of Horticulture and Forestry, Neri, Hamirpur
About
55
Publications
22,403
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1,306
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Introduction
Current institution
College of Horticulture and Forestry, Neri, Hamirpur
Current position
- Professor (Assistant)
Additional affiliations
November 2018 - present
January 2018 - September 2018
May 2017 - December 2017
Education
January 2011 - August 2014
Publications
Publications (55)
Disease control is largely based on the use of fungicides, bactericides, and insecticides—chemical compounds toxic to plant invaders, causative agents, or vectors of plant diseases. However, the hazardous effect of these chemicals or their degradation products on the environment and human health strongly necessitates the search for new, harmless me...
The chlorophenolic mycotoxin ochratoxin A (OTA) is prevalent in food sources and represents a potential health hazard to various animals. OTA is a potent renal carcinogen in rodents and has been linked to the fatal human kidney disease, Balkan Endemic Nephropathy (BEN). Understanding the mechanism of OTA-mediated toxicity is vital for the assessmen...
A series of experiments were performed to evaluate the biochemical response of Indian mustard (Brassica juncea) and rapeseed (B. napus) to salicylic acid (SA) and benzothiadiazole (BTH). Four treatments of SA and BTH were given to 10 week old plants upto four consecutive weeks. Antioxidative enzyme activities and phenolic contents were evaluated af...
Aonla and soybean are the potential tree and agricultural crops of subtropical region of Himachal Pradesh, India. However, the potential of these crops under agroforestry system has not been explored under these conditions both from ecological and economical point of view. Therefore, to promote aonla-based agroforestry system in subtropical conditi...
In developing countries, significant fruit and vegetable losses stem from inadequate storage and mishandling during harvest. Employing edible coatings on agricultural products offers an alternative method to reduce these losses as it aids in controlling the flow of moisture and gases between the product and its immediate environment. A significant...
Rheum species belong to the Polygonaceae family and are found in the
temperate and subtropical regions of Asia continent. The species belonging
to the genus Rheum are known as Rhubarb. Indian or Himalayan Rhubarb
includes Rheum australe, R. webbianum, R. moorcroftianum, and R.
spiciforme. These species are found at altitudes that range from 3,000 t...
Artemisia nilagirica is an important medicinal plant found to exhibit several medicinal properties but the use of its leaves for combating E. coli infection has not been scientifically validated in poultry. The present study was conducted to evaluate the protective effects of methanol leaf extract of A. nilagirica (ANE) on E. coli challenged broile...
Harar (Terminalia chebula) and soybean (Glycine max) are the potential tree and agricultural crops of subtropical region of Himachal Pradesh, India, however the potential of these crops under agroforestry system has not been explored both from ecological and economical point of view. The objective of this paper was to determine the effect of harar–...
Keywords High light stress decreases the photosynthetic rate in plants due to photooxidative damage to photosynthetic apparatus, photoinhibition of PSII, and/or damage to PSI. The dissipation of excess energy by nonphotochemical quenching and degradation of the D1 protein of PSII and its repair cycle help against photooxidative damage. Light stress...
An experiment on aonla-soybean intercropping was conducted at the experimental farm of the Department of Silviculture and Agroforestry, College of Horticulture and Forestry, Neri–Hamirpur, H.P., India during the year 2020–21 with an objective to determine the effect of aonla trees on growth, yield and quality parameters of soybean crop. The experim...
Vegetable crops benefit from seed priming technology by their low volume and high value. Early sowing of vegetables under suboptimal environments is practised often to fetch better remuneration in the market, although simultaneously it compels the farmers to use high seed rates to compensate for poor seedling emergence. To tackle this problem, farm...
Respiration and photosynthesis are indispensable plant metabolic processes that are affected by elevated temperatures leading to disruption of the carbon economy of the plants. Increasing global temperatures impose yield penalties in major staple crops that are attributed to increased respiratory carbon loss, through higher maintenance respiration...
High temperature challenges global crop production by limiting the growth and development of the reproductive structures and seed. It impairs the developmental stages of male and female gametogenesis, pollination, fertilization, endosperm formation and embryo development. Among these, the male reproductive processes are highly prone to abnormalitie...
Agriculture is the key sector that is threatened by climate change in which major entities like drought and heat destabilize food security and livelihoods. Abiotic stresses like drought, heat, and salinity cause physical, physiological, and biochemical changes during different stages of plant growth and development, finally affecting the economic y...
An increase in technological interventions and ruthless urbanization in the name of development has deteriorated our environment over time and caused the buildup of heavy metals (HMs) in the soil and water resources. These heavy metals are gaining increased access into our food chain through the plant and/or animal-based products, to adversely impa...
Hydrogen sulfide (H2S) is a small, reactive signaling molecule that is produced within chloroplasts of plant cells as an intermediate in the assimilatory sulfate reduction pathway by the enzyme sulfite reductase. In addition, H2S is also produced in cytosol and mitochondria by desulfhydration of l‐cysteine catalyzed by l‐cysteine desulfhydrase (DES...
Lahaul valley of Himachal Pradesh is inhabited by the tribal communities who believe in Amchi system of medicine which is being practiced in this region from a long time. The Amchi system of medicine is similar to the Ayurvedic medicine as this system involves the use of plants as the main source of drug or treatment strategy. Considering the impor...
Priming is used to increase vigor, germination synchronization, seedling growth, and field establishment by advancing metabolic processes within seeds. Seed respiration is a good indicator of the metabolic processes that lead to transition toward germination. Onion seeds (cv. Pusa Ridhi) subjected to osmopriming (−1.5 MPa PEG6000 for 7 days), magne...
Priming is used to increase vigor, germination synchronization, seedling growth, and field establishment by advancing metabolic processes within seeds. Seed respiration is a good indicator of the metabolic processes that lead to transition toward germination. Onion seeds (cv. Pusa Ridhi) subjected to osmopriming (−1.5 MPa PEG6000 for 7 days), magne...
Method for juice extraction and storage of aonla juice cv. NA-7 and Desi (Seedling) aonla was optimized. Out of four different combinations, enzymatic pretreatment of grated aonla mass by adding 1000ppm pectinase enzyme at 50°C for 4 hours followed by juice extraction in screw type juice extractor resulted in a significant improvement in juice yiel...
Technology for utilization of guava fruit for preparation of dried slices was optimized by osmotic dehydration technique. The guava fruit cultivar Lalit and Shweta were selected for preparation of dried slices. The slices of 6 mm thickness were pre-treated with 0.2% KMS+0.5% CaCl2. The slices were then treated with different osmotic concentration v...
Plants experience various stresses during the course of their growth and development. Seed priming involves the induction of a particular physiological stage of growth in the seed, prior to germination, using different approaches like hydro-, osmo-, chemical, hormonal, biological, matrix, and magnetopriming. Seed priming-induced early vigor in crop...
Lipoxygenases are universally distributed non-heme iron-containing dioxygenases, widely found in plants and animals. Lipoxygenases catalyzes the addition of an oxygen molecule to polyunsaturated fatty acids such as linoleic acid and linolenic acid. The syntheses of a group of acyclic or cyclic compounds collectively called oxylipins are initiated b...
Seeds of tomato were magnetoprimed at 100 mT for 30 min followed by imbibition for 12 and 24 h, respectively, at 20 °C, to examine the biochemical and molecular changes involved in homeostasis of hydrogen peroxide (H2O2) and its signaling associated with hormone interactions for promoting vigor. The relative transcript profiles of genes involved in...
Listeria monocytogenes is a Gram-positive intracellular food-borne pathogen capable of infecting both humans, as well as animals. The pathogen is responsible for causing invasive listeriosis, gastroenteritis, septicemia, endocarditis, meningitis, rhombencephalitis, perinatal infections, ophthalmitis, and abortion. The pathogen is difficult to manag...
Mycotoxins are the toxic compounds produced by fungi of Aspergillus, Penicillium, and Fusarium genera that contaminate food or feedstuffs and contribute to the occurrence of a serious health problem called mycotoxicosis in animals and humans. The most important food mycotoxins are aflatoxin, a liver-damaging toxin; ochratoxin A, associated with kid...
The present study was designed to check in vitro efficacy of different medicinal plant extracts against selected animal and poultry pathogens. We have used 20 different plant extracts to screen their antimicrobial activity against Escherichia coli, Salmonella Gallinarum and Salmonella Typhimurium. For this investigation we have prepared plant extra...
Mushrooms are the distinctive and visible fruiting
bodies of macroscopic filamentous fungi that grow
above or below ground surface. Mushrooms have been
a part of the human diet as a source of both food and
medicine for centuries. Edible mushrooms are a
valuable source of nutrients and bioactive compounds
in addition to a growing appeal for humans b...
A field experiment was conducted during 2011-12 at Punjab Agricultural University, Ludhiana, India to assess the effect of foliar application of elicitors viz., salicylic acid (SA) and benzothiadiazole (BTH) on biochemical constituents of Brassica seeds. Seeds of Brassica juncea and B. napus were sown in the field during rabi season. Four different...
The present investigation was aimed to assess the effect of different concentrations of elicitors viz., salicylic acid (SA) and benzothiadiazole (BTH) on physiomorphological and biochemical parameters of Brassica juncea and B. napus cultivars. The field experiment was conducted during 2012-13 at Punjab Agricultural University, Ludhiana, India. Four...
Alternaria blight, caused by Alternaria brassicae (Berk.) Sacc., is one of the serious diseases of Brassica species. A field experiment was conducted to evaluate the effects of two elicitors, salicylic acid (SA) and benzothiadiazole (BTH), on defense response induction in Brassica juncea and B. napus against Alternaria blight. Four different treatm...
Essential oil from different plant parts of Chromolaena adenophorum Spreng. growing in North-Western Himalayas was procured by hydro-distillation and analyzed by gas chromatography - mass spectroscopy (GC-MS). The oils were rich in variety of compounds known for their specialized properties. The essential oil from Chromolaena aerial parts was rich...
Four varieties of tall fescue (Hima-1, Hima-4, Hima-5 and EC-178182) and three varieties of Setaria (PSS-1, S-20 and S-92) were analyzed for variation in chemical composition viz., dry matter, crude protein, neutral detergent fibre (NDF), acid detergent fibre (ADF), hemicellulose, oxalate content and in vitro dry matter digestibility (IVDMD) at dif...
Livestock rearing plays a significant role in the economy of the Himalayan people with dependence largely on grasslands and pastures. Golden Timothy (Setaria anceps Stapf.) is a palatable, drought resistant grass species having high tolerance to water logging conditions. It is better suited to the shallow soils and low rainfall situations. The crud...
The dried seeds of twelve varieties/genotypes of rice bean [Vigna umbellata (Thunb; Ohwi and Ohashi)] grown at research farm of NBPGR, Phagli, Shimla during 2008 were analysed for some biochemical constituents of nutritional significance. 100-seed weight ranged from 5.5 to 8.3 g, whereas the moisture content varied from 9.5 to 10.9. Significant var...
Significant variation in moisture, crude protein, oil, ash, crude fibre, carbohydrates, total sugars, limiting amino acids - methionine and tryptophan, in vitro protein digestibility and anti-nutritional factor viz. oxalate content of seventeen promising sesame genotypes were observed to range from 3.63 to 5.17 %, 17.21 to 26.77 %, 42.68 to 47.81 %...
The dry mature seeds of twenty eight genotypes of chenopod (Chenopodium album L.) were analysed for biochemical constituents of nutritional significance. Variation in moisture, crude protein, ether extract, ash, crude fibre and carbohydrate content was observed to vary from 7.6 to 11.5, 13.4 to 16.5, 3.8 to 8.1, 3.5 to 5.0, 6.2 to 10.9 and 53.4 to...
Oilseed crops are a valuable source of vegetable oils, providing edible and industrial oils. These edible oils serve a number of functions in our body and supply more than twice the energy furnished by either protein or carbohydrates. lndia is one of the largest producer of oilseeds in the world. Peanuts, rapeseeds, mustards sunflower, soybean are...
The effect of storage on biochemical constituents viz moisture, protein, total sugars and free amino acids of sesame seed samples procured from different sources in India was studied at an interval of two months for the period of six months, which were stored in different storage containers vie. gunny bag, polythene bag and metallic bin. The study...
Questions
Questions (3)
PhD biochemistry candidate is required for the post of guest faculty. Interested candidates can contact me asap.
I am in the process of preparing an edited book entitling "Natural products in drug discovery: Benefits, Challenges and Opportunities". The book will be published by Apple Academic Press, USA (Co publishing with CRC Press Taylor & Francis Group). The aim of preparing this edited book is to bring together the latest findings on the said subject by a galaxy of eminent, experienced scientists and active researchers who can present the latest developments in the field. As you are an expert in this subject area, I am approaching you with the request to contribute a chapter. Please send your consent along with the title of the chapter as early as possible in reply by email at thakurmeenakshi94@gmail.com.
Tentative chapter titles are:
Book title: Natural products in drug discovery: Benefits, Challenges and Opportunities
Chapter titles:
1. Natural products as drug candidates
2. Traditional knowledge for drug discovery
3. Plant derived natural products
4. Bioactive molecules from marine sources and their potential use in drug discovery
5. Natural products from microbes
6. Natural products with antimicrobial properties
7. Natural products with immunomodulatory properties
8. Natural products with anticancerous properties
9. Natural products with anti-inflammatory and hepatoprotective properties
10. Natural products with antiviral properties
11. Natural products for curing lifestyle diseases
12. Approaches to develop drugs from natural products
13. Strategies for isolation and identification of bioactive molecules from natural sources
14. Semi synthetic drugs based on lead compounds from natural products
15. Role of OMICs in natural products based drug discovery
16. Bioprospecting and commercializing natural products
17. Challenges and opportunities in natural products based drug discovery
I have done LC-MS of the methanolic extract of Artemisia leaves. I have got the chromatogram, but due to the unavailability of the mass library I am not able to interpret the results. How can I identify the compounds present in the extract?
