Meda-Lavinia Negrutiu

• DMD, PhD
• Dean of the Faculty of Dental Medicine at Victor Babeș University of Medicine and Pharmacy Timișoara

Aim and objectives: To analyze implant mechanics under loading using Finite Element Analysis (FEA) to assess micro-movements, identify failure points, and optimize design for improved clinical outcomes. Materials and methods: A numerical simulation of mechanical loading on a prosthetic abutment attached to a dental implant was conducted using ANSYS...

Objective: This study aims to evaluate the influence of pontic length and design on the fracture resistance of zirconia fixed dental prostheses (FDPs). By assessing different span lengths under controlled mechanical loading conditions, the research seeks to provide insights into optimizing the structural integrity of zirconia dental bridges. Materi...

Aim of the study: This study aims to comparatively analyse two chemo-mechanical caries removers, Carisolv and BRIX3000. The study involves physico-chemical characterization of the substances followed by assessing their impact on carious lesions using extracted teeth. Materials and Methods: Carisolv, a caries removal gel, and BRIX3000, a gel from pa...

The professional relationship between dentists and patients encompasses the provision of medical care and needs to be completed by an ethical and accurate communication. This highlights the significant emphasis placed on the interaction between medical staff and patients in medical practice. The success of dental treatments also hinges on the denti...

Introduction: The integration of CAD/CAM technology with high-strength ceramics enables the creation of all-ceramic restorations, even in posterior regions. These restorations are typically composed entirely of ceramic material. Alternatively, a high-strength ceramic substructure can be utilized, necessitating ceramic veneering and glazing. CAD/CAM...

The development and enhanced performance of restorative dental materials—both direct and indirect restorative materials, along with adhesives—are paving the way for minimally invasive dental treatments. High-performance composite resins and ceramic materials, when appropriately matched to the clinical case, ensure excellent restorative outcomes. Th...

Introduction: Over the years, centrifugation systems have undergone significant transformations, adapting in shape to facilitate their application in dental clinics and advancing in operational technology. While centrifuge designs may vary in numerous ways, one critical distinction between the centrifuge is the angle at which centrifugation takes p...

Introduction: Currently, there is significant interest in the early detection and treatment of cavities. Dental caries, the primary cause of tooth decay, ranks among the most prevalent chronic oral diseases globally. Caries develops due to multiple cycles of demineralization and remineralization, which are natural processes occurring within the ora...

Background: Removable prostheses have seen a fundamental change recently because of advances in polymer materials, allowing improved durability and performance. Despite these advancements, notable differences still occur amongst various polymer materials and processing technologies, requiring a thorough grasp of their mechanical, physical, and ther...

(1) Background: This study examines the issue of malpractice accusations related to medical procedures in case of minor patients belonging to specific religious sects, focusing on both legal and ethical perspectives. The analysis particularly addresses the consequences of disregarding the refusal of legal guardians to consent to blood transfusions....

Introduction: Dentine hypersensitivity (DH) is a significant dental health concern characterized by sharp pain in response to stimuli on exposed dentine. It poses a diagnostic challenge due to its similarity to pain caused by other dental conditions. This condition predominantly affects adults, with canine and premolar teeth being the most commonly...

Medical criminal liability is a current, leading to a series of consequences regarding the future professional life of doctors. In the context where the health and safety of patients are major priorities, understanding legal medical responsibility is essential for ensuring the quality of medical services and preventing the commission of acts that c...

Background: Removable prostheses have seen a fundamental change recently because of advances in polymer materials, allowing improved durability and performance. Despite these advancements, notable differences still occur amongst various polymer materials and processing technologies, requiring a thorough grasp of their mechanical, physical, and ther...

The knowledge and compliance of dentist’s professional obligations related to the relationship with patients is a theoretical and a practical current topic. Knowing the consequences that may arise from a legal perspective and the violation of the legislation, determines of a preventive attitude of the dentists. Regarding the dentist’s knowledge and...

To ensure the most pleasant and efficient experience for patients diagnosed with autism spectrum disorder in the dental office, collaboration and attention for their needs are essential. Adapting communication strategies to the individual needs of autistic patients can make a significant difference in creating a comfortable environment and build a...

Aim of the Study: The study aimed to develop and evaluate two new hot chocolate recipes (P1 - Red Recipe and P2 - Green Recipe) and compare them with a commercial hot chocolate product (P3 - "La Festa"). The focus was on creating recipes that are nutritionally comparable to natural or dietetic products, with reduced sugar and increased dietary fibr...

Aim and objectives; Prevention of medical malpractice is a current topic for both doctors and lawyers. Considering the consequences, proof of errors in medical practice becomes an issue that need to be considered in daily practice. Material and method; Regarding the malpractice prevention in dental medicine, a 10 questions questionnaire was drawn u...

Acrylic resins dominated dentures technology for several decades. Due to their many disadvantages, new types of polymers, with better properties, suitable for dental prosthodontics applications were constantly attempted. The choice of polymeric materials and manufacturing technologies has experienced significant development in recent years. Differe...

Periapical odontogenic granulomas are among the most encountered pathology that involve the alveolar bone, with severe consequences such as bone resorption, the presence of inflammatory infiltrate and the formation of abnormal vascularization. The present study aimed to quantify the existence of the microvessel density (MVD), mast cell density (MCD...

The current chapter, entitled “Indirect restorative polymeric dental materials,” is dedicated to one class of dental materials with wide indications in dental medicine. The chapter is an overview of polymeric resin composites dedicated to indirect restauration currently used and latest avail resin composite and polymers in dentistry. This chapter i...

Mesenchymal stem cells currently play an important role in the tissue engineering field in developing new regenerative approaches. The oral cavity is a rich source of mesenchymal stem cells, and introducing the use of dental stem cells, characterized by a multilineage differentiation potential, immunomodulatory activity and repair capacity, offers...

The aim of this work is to assess the crystalline structure modification of an SLM Co-Cr-W dental alloy, veneered with two different ceramics, by means of X-ray diffraction (XRD), atomic force microscopy (AFM), and scanning electron microscopy, coupled with energy-dispersive spectroscopy (SEM-EDS). Ten identical plates were fabricated using SLM and...

Aim and objectives The aim of this study is evaluation of metal-ceramic prostheses interface. The metallic frameworks were made with two technologies. Material and methods For samples manufacturing, was used the NeWay Open Technology Scanner. On the virtual cast, was designed the metallic framework with EXOCAD program for SLS. The patterns for the...

Aim and objectives Dental practice is tending to remove the metallic component of fix partial prosthesis due to unfavourable mechanical behaviour. The polymers are used for prosthesis with metal free infrastructures and optimal function. Material and methods Polymers used for provisional prosthesis can be used with different technologies and have d...

The medical act requires the patient's consent, and the foundation of this condition imposed under the legal provisions is the respect for the physical integrity, freedom and self-determination of each person. In order to carry out this study on the legal and practical implications of informed consent in dentistry, a questionnaire was drawn up cons...

The present chapter is proposing a detailed and illustrated description of dental morphology of permanent dentition. The main topics are related to nomenclature, age of emergence, a description of teeth’s tissues (pulp, dentin, enamel, and cement), and morphology of all permanent teeth. The main focus of this chapter is the description of individua...

Three ceramic and composite computer-aided design/computer-aided manufacturing (CAD/CAM) materials from different manufacturers (Cerasmart (CS)—nanoceramic resin; Straumann Nice (SN)—glass ceramic and Tetric CAD (TC)—composite resin) were tested to investigate the biocompatibility and sustainability on human fibroblasts and keratinocytes cells. Eac...

Background and Objectives: The excessive use of smartphones for various tasks led to a new adverse postural phenomenon called text neck. The aim of this study was to investigate the effect of the text neck posture (TNP) on static occlusion by using the T-scan III occlusal diagnostic system. Materials and Methods: Nineteen subjects (aged 20 to 24 ye...

3D-printing application in dentistry not only enables the manufacture of patient-specific devices and tissue constructs, but also allows mass customization, as well as digital workflow, with predictable lower cost and rapid turnaround times. 4D printing also shows a good impact in dentistry, as it can produce dynamic and adaptable materials, which...

Maintaining the original trajectory of the root canal is a major challenge in endodontic therapy, especially in narrow and curved root canals. The present study aims to assess the shaping capacity of three endodontic systems made of different nickel-titanium alloys on simulated curved root canals. Thirty-six endodontic resin blocks (Ref. V040245, V...

This systematic review and meta-analysis aimed at assessing the diagnostic accuracy of emerging technologies, such as laser fluorescence (LF), transillumination, light-emitting diode devices, optical coherence tomography (OCT), alternating current impedance spectroscopy, fluorescence cameras (FC), photo-thermal radiometry, and modulated luminescenc...

Purpose/Aim In vitro studies have shown that rapid penetration of bacteria in the entire root canal system may occur after endodontic treatment without an efficient coronal seal. A proper restorative technique is necessary to ensure this, but there are a lot of materials out there. The aim of this study is to determine which type of restorative mat...

Purpose/Aim The focus of this study is twofold; the first objective is to evaluate the resistance of veneer-retained anterior fixed partial dentures to compression testing. The second objective is to determine if veneer retainers with these axial grip extensions improve the restorations resistance to compressive forces as demand for biomaterial and...

Purpose/Aim Due to the latest progress of 3D scanning and printing technology in the medical field, attempts have been made to apply this technology also in preventive orthodontics in order to obtain an aesthetic dental space maintainer. The aim of this study is to observe the mechanical load distribution on a SLA band and loop space maintainer in...

The aim of this ex vivo study is to assess with digital microscopy the thickness of luting space of metal free FPP made with technologies: selective laser sintering, milling and pressing. Twelve metal free FPP were designed after two technological protocols. The first group was made with pressed ceramic (IPS E.max Ceram). The veneering was made wit...

Despite high aesthetics, shade of full ceramic restoration can be a difficult task specially in case of anterior single crown restorations. For the first group, ten ceramic crowns for anterior teeth were made from IPS e.max Cem. The pressed ceramic cores were veneered with feldspathic ceramic IPS e.max.Ceram. For the second group were milled ten sa...

The epidemiology of OSCC continues to increase despite the progress that has been made. More than ever, the diagnostic approach process needs to focus on genetic and epigenetic alterations. The aim of our study was to identify and correlate the presence of COL9A1 gene variants in two types of samples from OSCC patients. Methods: Our pilot study inc...

Objectives: The goal of endodontic therapy is mechanically cleaning and shaping the root canal system, the removal of organic and inorganic debris followed by sealing with permanent filling materials. Materials and methods: Therefore, the aim of this in vitro study was to engage three imagistic methods: (i) en face (ef) time domain (TD) optical...

Background and Objectives: The aim of the present study is to compare the efficacy of three root canal preparation systems in the shaping of 3D-printed root canal replicas of single rooted teeth. Materials and Methods: Sixty 3D-printed root canal replicas were produced and divided into three groups, each consisting of twenty samples. Each group was...

In modern endodontics, nickel-titanium (NiTi) rotary instruments are used on a large scale for root canal shaping. Nevertheless, the separation of an instrument is a serious concern during shaping. The aim of this study is to determine and compare the torsional fracture characteristics of three types of NiTi endodontic instruments, each with differ...

Optical coherence tomography (OCT) is a non-invasive, non-radioactive optical diagnostic method based on low-coherence interferometry, which achieves images with different orientation. In dentistry, its major advantage is represented by the localization and characterization of the smallest defects in hard dental tissues, dental materials and of the...

The design and development of ceramic structures based on 3D scaffolding as dental bone substitutes has become a topic of great interest in the regenerative dentistry research area. In this regard, the present study focuses on the development of two scaffold-type structures obtained from different commercial dental ceramics by employing the foam re...

In vitro studies have shown that rapid penetration of bacteria in the entire root canal system may occur after endodontic treatment without a coronal seal. A proper restorative technique is necessary to ensure a coronal seal and protection of the residual dental structure. The aim of this in vitro study was to evaluate the coronal sealing ability o...

Objectives: The purpose of this study was to demonstrate the efficacy of Silver Diamine Fluoride (SDF) antibacterial solution in penetrating the demineralized areas of enamel. Materials and methods: It was considered a group of four extracted teeth (with no color fading, fissures, decay, or demineralization). Each tooth was sectioned in two equa...

Background Periodontal disease is an inflammatory, dysbiotic condition. Studies have shown that in the elderly, periodontal disease was associated with cognitive dysfunction and Alzheimer’s disease. Objective To investigate whether young healthy subjects with periodontal disease have lower cognition compared to those without periodontal disease. T...

Restorative dentistry is based on a continuous development of materials that make the best possible connection with dental tissues. Thus, dental adhesives have been researched with increasing interest. A successful adhesive system depends very much on its chemistry, as well as on the clinical procedures that must be appropriate for that type of den...

Introduction: Musculoskeletal disorders (MSDs) caused by incorrect working posture among dentists is a serious issue and one that leads to decreased productivity and quality of life. Aim: The aim of this study was to evaluate the impact of MSDs caused by postural errors in dental healthcare professionals on the body's center of gravity through a...

Dental adhesives are used in a wide range of applications, including to place direct composite restorations in frontal or posterior teeth. One of the most frequent causes for the failure of composite resin restorations is microleakages. The first aim of this work is to introduce a new type of self-etched dental adhesive doped with magnetic nanopart...

Fast, economic, and noninvasive, molecular analysis of saliva has the potential to become a diagnostic tool of reference for several local and systemic diseases, oral cancer included. The diagnosis of Oral Squamous Cell Carcinoma (OSCC) can be performed using high specificity and sensibility biomarkers that can be encountered in the biological flui...

Aim and objectives: This study will try to emphasize the differences between different materials and technologies currently used for dental crown manufacturing. Materials and methods: We performed 4 different types of dental crowns, using different materials and technologies, on the same preparation, on 4 different duplicate models, and we examined...

Composite resin materials for posterior restorations are becoming more and more popular. According to the market, Ormocer materials are more expensive than composite resin this paper is comparing the resistance to fracture between nanohybrid composites and Ormocers under vertical forces to evaluate their cost efficiency in the dental cabinets. 20 t...

Background Posture is influenced by many factors and dental occlusion seems to have its role on postural stabilization. Our rationale to perform the study was to find out if there are differences of static plantar pressure and stabilometric parameters depending on different dental conditions. Methods The observational study consisted in plantar pr...

The aim of the study was to determine the marginal and internal adaptation after curing of different composite resin restorations, using a nondestructive X-ray micro-computed tomography (micro-CT). Forty previously extracted human molars, kept in 10% formalin to preserve the bonding capabilities of the tooth structures, were divided into four group...

Musculoskeletal disorders (MSDs) caused by incorrect working positions among dentists is a serious health issue and one that leads to decreased productivity and quality of life. Muscle activity and strain is correlated with higher surface temperatures due to increased metabolic activity [2]. The main objective of this study is to evaluate, using th...

Recent assessments show an increase in the incidence of tooth decay. In addition to prophylactic treatments using fluoride and diet focused on low sugar consumption, application of sealing materials to the teeth surfaces is the best protection against the appearance of dental caries on both temporary and permanent teeth.Tooth sealing applied using...

The main properties of dental adhesives should be good marginal adaptation, high retention strength and the possibility of not negatively influencing clinical sustainability. Dental adhesives are continuously improving to increase their retention to dental structures by increasing penetration in these structures, as it was shownin the in-vitro test...

Dental decay is an infectious disease that affects more and more people. Dental Restoration Materials are not infallible, after filling a tooth with composite materials, and secondary caries may appear. One of the possible causes involved in the appearance of secondary caries is generated by the uneven thickness of the layer of adhesive that can be...

Background: The goal of this study was to determine the distribution of periodontal disease in a population seeking oral rehabilitation in a Romanian prosthodontics department and to identify the factors associated with each type of periodontal condition. Methods: The study population consisted of patients presenting consecutively to the Prostho...

We fabricate a hybrid magnetorheological elastomer (hMRE) based on a microfiber cloth soaked with a mixture containing magnetorheological suspension (MRS) and silicone rubber (SR). Two parallel copper electrodes are attached to the hMRE and the capacitance C is measured as a function of time for fixed values of magnetic flux density B. We show that...

The aim of the study was to evaluate and to compare the interface and marginal leakage of dental composite resins using confocal laser scanning biological microscopy (CM). Ten class II cavities were prepared on the proximal surfaces of 10 extracted teeth, previously kept in 10% formalin to preserve the bonding properties of the tooth structures. Ca...

Flash-Free Orthodontic Adhesive System represents the latest technology in the field of orthodontics. In the present study the bonding technique is applied on CAD/CAM produced resin crowns. Ten resin blocks were shaped after an upper premolar crown design from the 3Shape Library, and they were divided in two groups: on Group 1, control, Clarity Adv...

The latest technology in the field of orthodontic materials is represented by the Flash-Free Orthodontic Adhesive System. In the present study this novel technique is compared with the conventional direct bonding method. Ten extracted human premolars were separated into two groups: in the Group 1, APC Flash-Free Adhesive Coated Appliance System (3M...

The aim of this in vitro study is to compare the load-to-fracture performance of polymethyl methacrylates (PMMA) provisional restorations manufactured with a traditional laboratory technique in comparison to a computer-assisted design and computer-assisted manufacturing (CAD-CAM) technique. Five interim threeunit fixed dental prostheses were fabric...

In most patients with complete or partially stretched edentations requiring a dental implant, there is insufficient alveolar bone for a proper morpho-functional prosthetic restoration. Therefore, in many cases a bone addition is required for the implant treatment. The aim of this study is to evaluate ex-vivo, with numerical simulations, a large man...

Introduction . Chronic periodontal diseases and dental caries are the primary reasons for tooth loss in adults, which is further increased in people with diabetes. In most cases of bone loss, the treatment of partial edentulous patients with implant supported restorations impose additional surgical procedures, like sinus lift elevation and bone aug...

The purpose of this case report is to evaluate the role of mini-implants hybrid expanders in the orthodontic treatment of narrow maxilla. A female patient with a skeletal asymmetry and unilateral posterior crossbitepresented for orthodontic treatment. Digital records were sent to the orthodontic laboratory. The orthodontic lab made the mini-implant...

3D printing paired with CBCT imaging technology could provide a more individualised approach to orthodontic diagnosis and tratment. The aim of the present study is to asses dimensional differences between the CBCT image and 2 types of 3D printed replicas of an impacted maxillary canine, and to determine whether this method could be used in the futu...

Implants have been around for many years already, having a lot of advantages and high success rates, by some authors even higher than 90%. Nevertheless, throughout the years, problems and failures have occurred in practice which led to bone loss around the implants and even, in some cases, to losing the implant itself. The phenomenon behind this pa...

The purpose of the research was to see the time-trends (2005/2006-2015/2016) of types and patterns of drug usage between the young adults from medical school in TimisCounty. The study is a comparison of two cross-sectional cohorts of student from Timis County, Romania (2005/2006: 365 females and 248 males; 2005/2016: 336 females and 123 males). In...

Materials used in orthodontics are constantly changing and improving, but biocompatibility remains one of their most important characteristics.The purpose of this study is to evaluate the in vitro cellular behavior of dental MSC cells when put in contact with metal and 3D printed resin orthodontic attachments.Cell monolayers were seeded in wells an...

Aim: The purpose of this study was to evaluate the accuracy of digital impressions taken with two different intra-oral scanners (with and without optical powder), by dentists with different level of experience. Material and methods: Two intra-oral scanning devices (Apollo DI and Cerec Omnicam, Sirona Dental GmbH, Germany) were used to obtain a d...

Implants and biomaterials used in hard and soft oral tissue augmentation are very complex, but predictable to use nowadays, as the technological advances haven't skipped this field of medicine. Cases that were impossible to treat with implant retained fixed prosthesis some years ago, have become the daily practice of oral surgeons and dentists arou...

Treatment of impacted teeth often implies placing a bonded attachment and using orthodontic forces to move the tooth into occlusion. The aim of the paper is to describe a novel methodology of manufacturing orthodontic attachments for impacted teeth using the latest CAD software and 3D printing technology. A biocompatible acrylic based resin was use...

Resin infiltration is considered a treatment option for initial caries lesions. To prevent enamel lesion s from further demineralization a complete and homogeneous penetration of low-viscosity resins should be accomplished. The aim of this study was to compare the penetration abilities of 3 commercial products: Icon (DMG, Germany), Fluorodose (Cent...

The aim of this in vitro study was to assess a new design that, to our knowledge, we have introduced (patent pending) for indirect dental veneers. Their effect on the retention and adhesive properties at their interfaces have been studied. Fourteen high performance polymeric (PEEK) dental veneers have been elaborated using a computer-aided-design (...

Implants are one of the most innovative and less invasive prosthetic procedures available. Almost all types of edentations can, nowadays, be treated with an implant-retained prosthetic piece, either fixed or removable. But regardless of the development in the industry over the last decades and the high success rate-estimated at over 95%-there are s...

The goal of the present study is to compare the marginal fit using microCT of ceramic inlays obtained using two different technologies: pressing technique (lithium disilicate) and milling technique (milled leucite glass-ceramic). After extraction of four caries-free mandibular first molars, first class inlay cavities were prepared. For each tooth t...

The replacement of classical fillings, especially in the posterior area with different types of inlays has become a common solution used in order to improve all parameters which insure a long lasting treatment. Vrious ceramic materials and systems are available, but so far an ideal ceramic material suited for all clinical situations, has not been f...