Md Abu Reza

University of Rajshahi | RU · Department of Genetic Engineering and Biotechnology

Machine learning is important in the treatment of heart disease because it is capable of analyzing large amounts of patient data, such as medical records, imaging tests, and genetic information, in order to identify patterns and predict the risk of developing heart disease. However, most ML algorithms require more accurate data in order to build an...

Nowadays, there has been a significant surge in the exploration of anticancer compounds derived from medicinal plants due to their perceived safety and efficacy. Therefore, our objective was to investigate the antioxidant and antiproliferative properties, along with the phytoconstituents, of methanol extracts from various parts of 15 selected Bangl...

Entire fever which has symptoms like fever, headache, or abdomen pains is mainly accompanied by two types of Salmonella bacteria; Salmonella typhoid and Salmonella paratyphoid. Salmonella paratyphoid has three subtypes: A, B, and C. Salmonella, which is a gram-negative bacterium, the tripartite multidrug efflux systems pump of this bacterium export...

The fascinating structural, optical, and electronic features of calcium nitrogen iodide (Ca3NI3) make it an attractive material for developing absorbers for efficient and reasonably priced applications involving solar cells. Potential applications as an absorber layer in heterostructure solar cells for the perovskite material Ca3NI3 have been thoro...

Objectives: Trimeresurus erythrurus (Red-tailed bamboo pit viper) contributes significantly to snakebite enve-noming cases in Bangladesh, India, Myanmar, and Nepal. However, the absence of specific antivenom and challenging socioeconomic conditions in these regions necessitate the development of symptom-based medication to mitigate the severity of...

Diabetes mellitus, a chronic metabolic disorder, continues to be a major public health issue around the world. It is estimated that one in every two diabetics is undiagnosed. Early diagnosis and management of diabetes can also prevent or delay the onset of complications. With the help of a variety of machine learning and deep learning models, stack...

Bangladesh is abundant in medicinal plants. The bioactive compounds in medicinal plants provide novel therapeutic opportunity of improving human health. But the benefit-risk balance is usually less considered during formulation of traditional medicine. However, the plants included in this study were not studied before regarding their hemolytic and...

Nomophobia is a term describing a growing fear in today’s world, the fear of being without a mobile device or beyond mobile phone contact. It is the biggest non-drug addiction of the 21st century and is mainly affected by teen-aged students. Those experiencing nomophobia may feel a sense of panic, anxiety, or distress when they are separated from t...

Generic diversity (GD) screening helps to identify candidate genes involved in diseases, pests, or other stress resistance in plants. GD is crucial for maintaining vigor and healthy plant population. The random amplified polymorphic DNA (RAPD) is a rapid polymerase chain reaction (PCR)-based molecular marker, effective for screening genetic diversi...

Generic diversity (GD) screening helps to identify candidate genes involved in diseases, pests, or other stress resistance in plants. GD is crucial for maintaining vigor and healthy plant population. The random amplified polymorphic DNA (RAPD) is a rapid polymerase chain reaction (PCR)-based molecular marker, effective for screening genetic diversi...

Lipid droplets (LDs) are storage organelles for neutral lipids which are critical for lipid homeostasis. Current knowledge of fungal LD biogenesis is largely limited to budding yeast, while LD regulation in multinucleated filamentous fungi which exhibit considerable metabolic activity remains unexplored. In this study, 19 LD‐associated proteins wer...

Type 2 diabetes is a chronic metabolic disease that affects a significant portion of the worldwide people. Pre-diction of this disease using different machine learning (ML) based algorithms has gained substantial attentiondue to its potential for early detection and effective intervention. One of the most powerful ML algorithm supportvector machine...

Feature engineering is treated as a crucial step in any intelligent system pipeline and practitioners often spend 70–80% of their time in this phase before modeling. Especially, in machine learning (ML), the performance of the classification systems deteriorates as irrelevant features are added, even when the features presented contain enough infor...

Lipoid proteinosis is a rare multisystem genodermatosis inherited as autosomal recessive trait. We report a case of lipoid proteinosis in a 10-year-old boy born to first-degree consanguineous parents presented with marked hoarseness of voice, accelerated photoaging appearance, enlarged and erythematous tongue with restricted movement and widespread...

The co-substrate is a crucial component in the bio-decolorization process that helps bacteria to grow and carry out their fundamental functions. Different types of textile dyes with diverse chemical structures are frequently employed in the textile industry, and the most of them are resistant to biodegradation because of their xenobiotic nature. Du...

As a disaster-prone country with unique geographical features, snake biting is a major public health concern in Bangladesh. The primary reasons of mortality from snakebite include late presentation to the hospital, low efficacy of antivenom, and a lack of adequate management facilities. Because snake venom characteristics vary depending on geograph...

Osteoporosis, a common skeletal disorder, necessitates the identification of its risk factors to develop effective preventive measures. It is crucial to identify the underlying risk factors and their relationships with the response class attribute. Different machine learning (ML) algorithms and feature selection approaches are used to estimate the...

This article reports the Chromobacterium amazonense BASUSDA_45 strain's draft genomic sequence. The bacterium was isolated from cypermethrin pesticide contaminated soil and then the sequencing was carried out. Initially de novo assembly of the raw sequences, trimming and quality check generates 125 contigs having N50 of 78,923. Further mapping of t...

The healthy liver plays more than 500 organic roles in the human body, while a malfunction may be dangerous or even deadly. Early diagnosis and treatment of liver disease can improve the likelihood of survival. Machine learning (ML) is a powerful tool that can assist healthcare professionals during the diagnostic process for a hepatic patient. The...

Lipid droplets (LDs) are storage organelles for neutral lipids. Our knowledge about fungal LD biogenesis is limited to budding yeast. Moreover, regulation of LD in multinucleated filamentous fungi with considerable metabolic activity is unknown. Here, 19 LD-associated proteins were identified in Aspergillus oryzae using colocalization screening of...

Litsea glutinosa (L. glutinosa) is considered an evidence-based medicinal plant for the treatment of cancer, the leading cause of death worldwide. In our study, the in vitro antioxidant and in vivo anticancer properties of an essential ethno-medicinal plant, L. glutinosa, were examined using non-toxic doses and a phytochemical analysis was executed...

Several factors affect germination and seedling growth for the successful establishment of crops. This study investigates the effect of medium pressure ( ∼ 10 torr) low-frequency glow discharge (LFGD) (Ar + Air) plasma-treated seeds for different periods (1, 3, 6, 8, and 10 min) of wheat. The scanning electron microscopy (SEM) image of the seed sur...

Development of effective vaccines have been immensely welcomed by the world to prevent the transmission of SARS-CoV-2. However, the duration and clinical implications of antibody-mediated natural immunity in SARS-CoV-2 have not been adequately elucidated alongside some other immune system transforming factors. In a cohort study, we measured NAb tit...

The phytochemical constituents, antioxidant, cytotoxicity and anti-cancer activities of Leucas indica bark extract in methanol were evaluated. Brine shrimp lethality assay was used to assess the cytotoxicity while antioxidant capability was determined by DPPH and H2O2 free radical scavenging assay. Cell growth inhibition was estimated through hemoc...

The investigation of traditional medicinal plants is gaining prime importance day by day due to having a wide range of bioactive phytochemicals. The presence of diverse bioactive compounds makes medicinal plants more demandable for curing several diseases, such as inflammatory diseases, diabetes, and cancer. Leucas indica is commonly found througho...

Background Plasma technology is an emerging sector in agriculture. The effect of low-frequency glow discharge (LFGD) plasma at medium pressure (10 torr) on maize morpho-physiological and agronomical behavior was investigated in the current studies. The LFGD plasma act as a secondary messenger to improve maize production. This cutting-edge plasma te...

Plasma technology is an emerging science in the field of agriculture. The goal of this study is to see how low-pressure dielectric barrier discharge (LPDBD) plasma generated from argon/air (Ar/air) mixture affects germination, growth, and yield of maize. LPDBD Ar/air plasma was applied to maize seeds via a bioreactor. Seeds were then planted in the...

Liver disease indicates inflammatory condition of the liver, liver cirrhosis, cancer, or an overload of toxic substances. A liver transplant may reinstate and extend life if a patient has severe liver disease. In the last few years, machine learning (ML) based diagnosis systems have played a vital role in assessing liver patients which eventually l...

We report the draft genome sequence of Klebsiella pneumoniae strain BASUSDALSc45PDB48, isolated from pesticide-contaminated soil; this strain showed the ability to grow in a medium with cypermethrin as the only carbon source. The genome assembly comprised 5,249,704 bp, with 128.17 Ns per 100 kbp, an N50 value of 5,035,968 bp, a GC content of 57.57%...

Plasma agriculture is an emerging technology, although the application of non-thermal plasma in wheat productivity is still in its early stage. This study deciphers the effect and mechanistic basis of non-thermal air-generated LPDBD (low-pressure dielectric barrier discharge) plasma in boosting germination, growth and nutritional properties in whea...

Bioremediation through biodegradation is applied for cleaning up several environmental pollutions including petroleum oil spill containing petrol, diesel, mobil, kerosene, lubricating, etc. which have devastated several endangered terrestrial and aquatic ecosystems. Therefore, the current research was aimed to isolate and identify diesel degrading...

Background: Cisplatin is an outstanding anticancer drug, but its use has been decreased remarkably due to sever nephrotoxicity. R. vesicarius L. is a leafy vegetable that is evident with anti-angeogenic, anti-inflammatory, anti-proliferative, hepatoprotective, and nephroprotective potential. Therefore, this study was designed to inspect its methan...

Oil contamination is a worldwide concern now. However, oil contaminated environment is enriched with microorganisms that can utilize petroleum oil and use hydrocarbon for their growth, nutrition and metabolic activities. In the present study, bacteria present in the oil contaminated soil were isolated by enrichment culture technique using Minimal S...

Ethnopharmacological relevance Tabebuia pallida (Lindl.) Miers (T. pallida) is a well-known native Caribbean medicinal plant. The leaves and barks of T. pallida are used as traditional medicine in the form of herbal or medicinal tea to manage cancer, fever, and pain. Moreover, extracts from the leaves of T. pallida showed anticancer activity. Howev...

Plasma agriculture is an emerging technology, although the application of non-thermal plasma in wheat productivity is still in its early stage. This study deciphers the effect and mechanistic basis of non-thermal air-generated LPDBD (low-pressure dielectric barrier discharge) plasma in boosting germination, growth and nutritional properties in whea...

Eco-friendly plasma technology is appeared as promising for the improvement of crop yield and hence it was applied to study the paddy plant growth and yield. Applications of plasma technology in this study are twofold: (1) paddy seeds (Oryza sativa L.) were treated with low pressure (100 torr) glow air discharge (LPGAD) plasma for duration of 30, 6...

Citrus macroptera, an indigenous fruit in Bangladesh, is usually used for folk treatment and culinary purposes. Considering its application context, this study was designed to detect and quantify the ascorbic acid (AA) content in C. macroptera fruit pulp juice (CMFPJ) by high performance liquid chromatography (HPLC) equipped with an ultraviolet det...

In this present study conducted with the LFGD (Low-Frequency Glow Discharge) (Ar & Oxygen) plasma treated maize seeds, to inspect the effect on seed surface modifications, seed germination, growth, development, productivity and nutritional compositions of maize plants. This study reported that LFGD (Ar & Oxygen) plasma treated maize seeds have a po...

Plasma agriculture is an emerging field. In this report, we studied the effect of medium pressure (~ 10 torr) low-frequency (3–5 kHz) glow discharge (LFGD) plasma on various agronomical and physiological attributes in wheat. Wheat seeds treated by LFGD plasma generated from Argon–Oxygen (Ar + O2) gas mixture and air showed a remarkable enhancement...

Food adulteration is a major problem throughout the world where food items are being processed indiscriminately using excessive amount of artificial food colors. Consequently, consumers are suffering from various physical complications. The present study was aimed to investigate the hazardous impacts of egg yellow food color through cytotoxicity...

Apoptosis plays a pivotal role in the exclusion of abnormal cells without any ruin of surrounding healthy cells. Generally, it occurs through an orderly and autonomously process which is controlled by proper function of various genes. Therefore, the current experiments detect the expression level/pattern of those genes to confirm the involvement of...

Medicinal plant-derived bioactive compounds have recently gained more interest in biological research as an important source of novel drug candidates. Phyllanthus acidus (L.) is a widely distributed herbal medicinal plant naturally used in Ayurvedic medicine in Bangladesh. The present study focused on exploring the biological potential as well as t...

Targeting apoptosis is a promising approach to inhibit the abnormal cell proliferation of cancer progression. Existing anti-apoptotic drugs, many derived from chemical substances, have often failed to combat cancer development and progression. Therefore, identification of apoptosis-inducing anticancer agents from plant-derived sources has become a...

Objectives: This study aimed to compare the physico-chemical and microbial quality of local milk samples from buffalo (B), cow (C), goat (G) and sheep (S). Methods: Milk samples (B, C, G, S, 1 litre each) were collected in sterile bottles from Rajshahi, the northern part of Bangladesh. The samples were analyzed to compare various physico-chemical p...

HMA (heavy metal associated) is a member of the ATPases protein family involved in metal transport in plants. This study characterizes several HMA3 homologs and infers their molecular functions in different plant species. Arabidopsis AtHMA3 (AT4G30120) was used as a reference to retrieve 11 HMA3 homologs having 97-100% query cover, 535-542 residues...

Tumor necrosis factor-alpha (TNF-α) is a major cytokine for inflammatory response in human body. This is also well linked with obesity and causing different pathophysiological problems in type 2 diabetic mellitus (T2DM) patients because of its pro-inflammatory over expression. However, seemingly harmless nucleotide changes in the promoter region of...

A novel bis[benzyl-N 0-hydrazinecarbodithioato-κ 2 N 0 ,S]nickel(II) complex was synthesized and characterized by means of various physical, chemical, and spectroscopic techniques. The X-ray single crystal diffraction analysis indicated two independent close comparable bis-chelated square planar complexes of trans-configuration, where S-benzyl dith...

A novel bis[benzyl‐N′‐hydrazinecarbodithioato‐κ² N′,S]nickel(II) complex was synthesized and characterized by means of various physical, chemical, and spectroscopic techniques. The X‐ray single crystal diffraction analysis indicated two independent close comparable bis‐chelated square planar complexes of trans‐configuration, where S‐benzyl dithioca...

A novel bis[benzyl-N 0-hydrazinecarbodithioato-κ 2 N 0 ,S]nickel(II) complex was synthesized and characterized by means of various physical, chemical, and spectroscopic techniques. The X-ray single crystal diffraction analysis indicated two independent close comparable bis-chelated square planar complexes of trans-configuration, where S-benzyl dith...

Nickel is a fundamental element for healthy life for human and higher animals. For biological importance, its complexation with bioactive ligand is worth to be studied with the aim to understand its function. Using mouse peri-toneal cancer model, MTT colorimetric assay and anticancer activity analysis, we examined the role of nickel(ll) complex in...

A safer natural alternative to treat neoplastic cells by inducing apoptosis is a prime requisite. Therefore, the current study was to evaluate the antiproliferative activity of Morus laevigata , a wild‐type Mulberry species. Antioxidant and cytotoxic activity of aqueous extracts of M. laevigata leaf (MLL) and M. laevigata bark (MLB) were evaluated....

Abroma augusta (L.), one of the herbal medicinal plants, is widely used for treatment of various maladies. The present study was initiated to determine the antioxidant, hemolytic, cytotoxicity, and anticancer activities of methanolic extract from the bark of the plant. The phytochemical screening was done by analyzing different phytochemicals prese...

Excessive use of pesticides in agricultural fields is a matter of great concern for living beings as well as the environment across the world, in particular, the third world countries. Therefore, there is an urgent need to find out an effective way to degrade these hazardous chemicals from the soil in an environment‐friendly way. In the current pro...

Applications of nonthermal plasmas in agriculture are drawing much interest to the researchers because of its significant effects on seed germination, plant growth and development. This study investigates the effects of plasma activated water (PAW) on seed germination, seedling growth and antioxidant enzymes of black gram (Vigna mungo L.) (Local na...

Cadmium (Cd) is detrimental to crops and the environment. This work examines the natural mechanisms underlying silicon‐ (Si‐)directed Cd detoxification in rice plants. The addition of Si to plants under Cd stress caused significant improvements in morphological parameters, chlorophyll score, F v /F m and total soluble protein concentration compared...

Effects of black gram (vigna mungo L.cv. Barimash 3) seed treatments with 400 torr dielectric barrier discharge (DBD) air plasma on seed surface morphology, seed germination, seedling growth and antioxidant enzyme activities in the roots, shoots and leaves were investigated. The plasma discharge voltage, frequency, electrode spacing, gas temperatur...

Chemical fertilization in agriculture is threatening to the ecosystem. Therefore, the use of eco-friendly stimulant for crop revolution is highly desirable. This study investigates the effects of plasma activated water (PAW) created by treating de-ionized water with high voltage discharge on black gram. Results showed significant improvements in di...

Cancer is the second death causing disease all over the world and until today 100 different types of cancer have been identified whose treatment methods consist of serious side effects on human body. To reduce the frequency of adverse effects of cancer treatment, nowadays plant derived natural components are getting priority. The plant Morus latifo...

The outermost layer of human skin is epidermis which provides a consistent barrier to human from many agent including the exposure to UV irradiation. Ultraviolet light emitted from the sun is highly prevalent on earth. The ozone layer completely filters out the very harmful UV-C (100-280 nm) component, and most of UV-B (280-315 nm), but a large fra...

The study deals with the effect of low pressure dielectric barrier discharge (LPDBD) plasma and plasma activated water (PAW) produced with Ar, O2 and Air on germination and growth in rapeseed. Although H2O2 concentration showed no significant changes, α‑amylase activity (germination inducer) significantly increased in seeds due to LPDBD plasma. In...

Putranjiva roxburghii Wall. (Euphorbiaceae) has long been used in folk treatment. Considering this folkloric background, this study was designed to evaluate in vitro antioxidant and antibacterial activity of P. roxburghii fruit peel (PRFP) enthanolic (95%) extract. Antioxidant activity was checked based on 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free...

Citrus macroptera (Rutaceae) has long been used in folk medicine in Bangladesh. Considering the folkloric context , this study was aimed to scrutinize anti-proliferative activity of C. macroptera fruit pulp juice (CMFPJ) against Ehrlich's ascites carcinoma (EAC). The anti-proliferative capacity of CMFPJ was investigated and confirmed primarily usin...