Md. Mominur Rahman

Md. Mominur Rahman
Daffodil International University · Department of Pharmacy

Master of Pharmacy
Currently, I am working on natural products and observing how they can play a vital role in neurological disorders.

About

64
Publications
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Introduction
There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it. The brain is the organ of destiny. Scientists are making great strides in identifying potential new ways to help diagnose, treat, and even prevent Alzheimer’s and related dementia. These advances are possible because thousands of people have participated in clinical trials and other studies.

Publications

Publications (64)
Article
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Citrus fruits are more important in all over the world. They are well known as nutritional and medicinal property. Lemon is one of the most common citrus fruit. Lemons are typically grown from seeds, which are planted and developed as trees. Trees of citrus fruit can stand from 10 feet to 20 feet tall, and can produce fruit for more than 30 years....
Article
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Nanoscale engineering is one of the innovative approaches to heal multitudes of ailments, such as varieties of malignancies, neurological problems, and infectious illnesses. Therapeutics for neurodegenerative diseases (NDs) may be modified in aspect because of their ability to stimulate physiological response while limiting negative consequences by...
Article
Once the World Health Organization (WHO) declared the COVID-19 (Coronavirus Infectious Disease-19) outbreak to be pandemic, massive efforts have been launched by researchers around the globe to combat this emerging infectious disease. Strategies that must be investigated such as expanding testing capabilities, developing effective medicines, as wel...
Article
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Neurodegenerative disorders, which are defined by the breakdown of neurons over time, are affecting an increasing number of people. Stroke, Alzheimer's, Parkinson's, Multiple Sclerosis, Migraine, and Amyotrophic Lateral Sclerosis are just a few examples of brain disorders that have no cure. Besides, there is a huge demand for drugs that can cure th...
Article
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Research on the immune system and cancer has led to the development of new medicines that enable the former to attack cancer cells. Drugs that specifically target and destroy cancer cells are on the horizon; there are also drugs that use specific signals to stop cancer cells multiplying. Machine learning algorithms can significantly support and inc...
Article
Dementia and frailty increase health adversities in older adults, which are topics of growing research interest. Frailty is considered to correspond to a biological syndrome associated with age. Frail patients may ultimately develop multiple dysfunctions across several systems, including stroke, transient ischemic attack, vascular dementia, Parkins...
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Considerable evidence supports that cytokines are important mediators of pathophysiologic processes within the central nervous system (CNS). Numerous studies have documented the increased production of various cytokines in the human CNS in various neurological and neuropsychiatric disorders. Deciphering cytokine actions in the intact CNS has import...
Article
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COVID-19, which is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly spread over the world, posing a global health concern. The ongoing epidemic has necessitated the development of novel drugs and potential therapies for patients infected with SARS-CoV-2. Advances in vaccination and medication development...
Article
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In the last two decades, considerable interest has been shown in understanding the development of the gut microbiota and its internal and external effects on the intestine, as well as the risk factors for cardiovascular diseases (CVDs) such as metabolic syndrome. The intestinal microbiota plays a pivotal role in human health and disease. Recent stu...
Article
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The main aim of this research was to explore Parthenium hysterophorus Linn phytochemically and pharmacologically. Phytochemical screening is important for the isolation of active compounds before bulk extraction. The crude extracts and their fractions were screened for enzyme (urease, α-glycosidase, and phosphodiesterase) inhibition assays, in vivo...
Article
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Immunotherapy, which stimulates the body’s immune system, has received a considera- ble amount of press in recent years because of its powerful benefits. Cancer immunotherapy has shown long-term results in patients with advanced disease that are not seen with traditional chem- otherapy. Immune checkpoint inhibitors, cytokines like interleukin 2 (IL...
Article
G protein-coupled receptors (GPCRs) are activated by manifold neurotransmitters, and their activation, in turn, evokes slow synaptic transmission. They are profoundly related to numerous psychiatric and neurological disorders such as schizophrenia and Parkinson's disease. The significant malady indications for GPCR modulators demonstrate a change t...
Article
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Diabetes mellitus (DM) is a metabolic syndrome. Diabetes has become more common in recent years. Chemically generated drugs are used to lessen the effects of DM and its following repercussions due to unpleasant side effects such as weight gain, gastrointestinal issues, and heart failure. On the other hand, medicinal plants could be a good source of...
Article
Diabetes mellitus is a metabolic condition that influences the endocrine framework. Hyperglycemia and hyperlipidemia are two of the most widely recognized metabolic irregularities in diabetes, just as two of the most well-known reasons for diabetic intricacies. Diabetes mellitus is a persistent illness brought about by metabolic irregularities in h...
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Neuroinflammation, a protective response of the central nervous system (CNS), is associated with the pathogenesis of neurodegenerative diseases. The CNS is composed of neurons and glial cells consisting of microglia, oligodendrocytes, and astrocytes. Entry of any foreign pathogen activates the glial cells (astrocytes and microglia) and overactivati...
Article
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Antimicrobials are a type of agent widely used to prevent various microbial infections in humans and animals. Antimicrobial resistance is a major cause of clinical antimicrobial therapy failure, and it has become a major public health concern around the world. Increasing the development of multiple antimicrobials has become available for humans and...
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Background: Lung diseases including chronic obstructive pulmonary disease (COPD), infections like influenza, acute respiratory distress syndrome (ARDS), asthma and pneumonia lung cancer (LC) are common causes of sickness and death worldwide due to their remoteness, cold and harsh climatic conditions, and inaccessible health care facilities. Purpose...
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In the current study, the folklore medicine, Syzygium cumini, was experimentally evaluated for anti-inflammatory, analgesic, sedative, and muscle relaxant effects. The extract and fractions of S. cumini were found safe up to 1000 mg/kg with no mortality, except for slight sedation as a minor side effect. Both, the extract and various fractions of S...
Article
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The current study aims at the neuropharmacological properties of ethanol, acetone, and ethyl acetate leaf extracts of Chassalia curviflora in mouse models. The neuropharmacological properties were studied in Swiss albino mice, which were provided doses of 50, 100, and 200 mg/kg body weight in thiopental sodium-induced sleeping time, and 100 and 200...
Article
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Current advancements in nanotechnology and nanoscience have resulted in new nanomaterials, which may pose health and environmental risks. Furthermore, several researchers are working to optimize ecologically friendly procedures for creating metal and metal oxide nanoparticles. The primary goal is to decrease the adverse effects of synthetic process...
Article
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Cancer is the world's second-leading cause of death, and the involvement of microbes in a range of diseases, including cancer, is well established. The gut microbiota is known to play an important role in the host's health and physiology. The gut microbiota and its metabolites may activate immunological and cellular pathways that kill invading path...
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In the present study, gold (Au) and silver (Ag) nanoparticles (NPs) were synthesized from aqueous extracts of Opuntia dillenii, characterized by various advanced techniques and investigated for antibacterial and antifungal potential. Phytochemical screening of O. dillenii showed the presence of alkaloids, betacyanin, saponins, tannins, flavonoids,...
Article
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Cancer is a fatal disorder that affects people across the globe, yet existing therapeutics are ineffective. The development of submicrometer transport for optimizing the biodistribution of systemically provided medications is the focus of nanomedicine. Nanoparticle- (NP-) based treatments may enable the development of novel therapeutic approaches t...
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Obesity and diabetes are the most demanding health problems today, and their prevalence, as well as comorbidities, is on the rise all over the world. As time goes on, both are becoming big issues that have a big impact on people’s lives. Diabetes is a metabolic and endocrine illness set apart by hyperglycemia and glucose narrow-mindedness because o...
Article
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the novel coronavirus responsible for the current global pandemic, which first emerged in December 2019. This coronavirus has affected 217 countries worldwide, most of which have enacted non-remedial preventive measures, such as nationwide lockdowns, work from home, travel bans, and so...
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Citrus limon L. is an ingenious alternative medication and has a broad scope in managing several health conditions as part of natural remedies. Recently, medicinal plants have witnessed incredible consideration worldwide in the field of neuroscience for remedial intervention. The present work has investigated the phytochemical compounds and neuroph...
Article
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The strategies involved in the development of therapeutics for neurodegenerative disorders are very complex and challenging due to the existence of the blood-brain barrier (BBB), a closely spaced network of blood vessels and endothelial cells that functions to prevent the entry of unwanted substances in the brain. The emergence and advancement of n...
Article
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Neurodegenerative diseases are a global health issue with inadequate therapeutic options and an inability to restore the damaged nervous system. With advances in technology, health scientists continue to identify new approaches to the treatment of neurodegenerative diseases. Lost or injured neurons and glial cells can lead to the development of sev...
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Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient information concerning the promising anticancer activity of this compound. The therapeutic efficacy of BBR has been reported i...
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Inflammation is a natural protective mechanism that occurs when the body’s tissue homeostatic mechanisms are disrupted by biotic, physical, or chemical agents. The immune response generates pro-inflammatory mediators, but excessive output, such as chronic inflammation, contributes to many persistent diseases. Some phenolic compounds work in tandem...
Article
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Several coronaviruses (CoVs) have been associated with serious health hazards in recent decades, resulting in the deaths of thousands around the globe. The recent coronavirus pandemic has emphasized the importance of discovering novel and effective antiviral medicines as quickly as possible to prevent more loss of human lives. Positive-sense RNA vi...
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The outbreak of HIV/AIDS is not yet high in Bangladesh but slowly increasing posing intimidation. The process of this review was carried out to explore the danger of HIV/AIDS to acquaint knowledge about prevention and transmission of HIV, attitudes unto HIV prevention and behaviors utter to HIV/AIDS. As an intervention strategy, provided training a...
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Natural products have been known for their antimicrobial factors since time immemorial. Infectious diseases are a worldwide burden that have been deteriorating because of the improvement of species impervious to various anti-infection agents. Hence, the distinguishing proof of antimicrobial specialists with high-power dynamic against MDR microorgan...
Book
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Recently, different researches on medicinal plants have grabbed attention worldwide in the field of neurosciences as medicinal plants are considered the safer source of drugs. Keep this in mind our current study was designed to find out neuropharmacological principles from methanol extracts of leave and root of Ceriscoides turgida. Traditionally, C...
Article
Lamin A/C encoded by LMNA gene is an important component for the maintenance of the nuclear structure. Mutation in the lamin A/C leads to a group of inherited disorders is known as laminopathies. In the human body, there are several mutations in the LMNA gene have been identified. It can affect diverse organs or tissues or can be systemic, causing...
Article
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Three fractions obtained by Kupchan partitioning of 70% methanol extract of leaves of Stevia rebaudiana with n-hexane, dichloromethane and ethyl acetate designated by HSR, DSR and ESR were investigated for their antioxidant and antimicrobial activities. HSR and ESR exhibited prominent free radical scavenging activity having IC50 value of 11.59 and...
Article
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Neurodegenerative disorders are consequences of the deterioration of cells and tissues with a mature undesirable way of life. The degenerative disease like Parkinson's disease (PD) influences Central nervous systems (CNS) and cardiovascular systems. In this study, we show Parkinson's disease combined with rising nanoparticles, draw hopeful methodol...
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Aims: The present study was performed to evaluate the phytochemical screening of compounds, thrombolytic activity, analgesic activity and antidiarrhoeal activity of the methanolic extract of of Cucumis sativus Linn. (Cucurbitaceae) leaves. Background: Cucumis sativus Linn. is generally disseminated all through the world especially in Asia, Africa a...
Article
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Aims: Anthelmintic and inflammation are corelated with various pathological conditions. Finding for natural healing agents with a better safety profile for treating of these conditions are ongoing due to multiple unwanted effects associated with synthetic pharmaceuticals. Therefore the aim of this study was to evaluate the anthelminthic and anti-in...
Article
Objective: The objective of this study was assessing the diverse pharmacological efficacies of methanolic extract of the whole plant of Gardenia coronaria Buch-Ham. This study illustrates the phytochemicals, antioxidants and thrombolytic activity which have the possibility to be used in the coming future to open a new line of investigation. The Gar...
Article
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A combination therapy is a therapeutic intervention in which more than one therapy is administered to the patient. Examples of combination therapy include treatment regimens that involves administering several separate pills, each containing a particular drug, or single pills that contain several drugs. The aim of this work is to spread the informa...
Article
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Cost effectiveness is a very important think to formulate a product. People can get good product with a low price they must prefer the product. For developing a drug, bioequivalence test must be needed because of ensuring the therapeutic performance of drugs which have undergone changes in manufacturing processes as well as in formulation-modificat...
Article
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Objectives: Present study was designed to evaluate Analgesic, Antidiarrhoeal and Antimicrobial activities of methanol and acetone extracts of fruit peels of Limonia acidissima L. by different methods. Method: The analgesic activity of the samples was studied using acetic acid-induced writhing model in mice. Castor oil-induced antidiarrheal activity...
Article
Objectives: In Bangladesh, Drug distribution process is very important cause of our increasing economic and development. In the recent days Model pharmacy has become an important theme of study for the student in pharmacy. In Bangladesh the introduction of the mode l pharmacy practice likes other skilled and semiskilled health professionals will ce...
Article
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Progeria is a rare syndrome, with an estimated incidence of 1 per 250,000 births. It is a fatal, genetically determined disease of childhood characterized by dramatic, premature aging that occurs at about 8 to 10 times the normal rate of aging. Because of this accelerated aging, a child of ten years will have similar respiratory, cardiovascular, an...
Article
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For preliminary assessment of toxicity the brine shrimp lethality assay is deliberated a useful implement. To assessment natural marine products for pharmacological activity before they are used as a general bio-assay it is essential to evaluate the appropriateness of the brine shrimp methods. Citrus limon L (lemon) is an excellent preventative med...
Article
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The Limonia acidissima L is one of the useful traditional medicinal plants. In the rural area a lot of people use the Limonia acidissima L. for treating indigestion, flatulence, diarrhoea, dysentery and haemorrhoids. The present study was aimed to evaluate the various pharmacological efficacies of methanolic and acetonic fruit peels extracts of Lim...
Article
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The aim of the study was to compare the production of bioethanol between banana and yam peel. Banana is one of the most popular tropical fruit consumed worldwide. Banana is a common term embracing a number of species or hybrid in the genus of the Musa of the Musacaea and cultivated mainly for its fruits. Yam is also a tuber crop in the plant genus...
Article
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Non-communicable diseases (NCDs) creates a new havoc globally. Bangladesh has been facing a dual burden of existing infectious diseases and escalating rise of NCDs like diabetes, heart disease, stroke, cancer, chronic respiratory disease, etc. For getting prepared for the challenge of these diseases, information regarding their distribution and det...
Article
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The aim of the study was to find out the phytochemical evaluation, cytotoxic, anthelmintic & thrombolytic activity from the leaves of Mikania micrantha. Mikania micrantha (Asteraceae), commonly known as mile-a-minute weed is an extremely fast-growing, perennial creeping weed. To study for Phytochemical evaluation was determined through qualitative...
Article
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The prime objective of the present study was to evaluate the habit of drinking water and its relation to the development of diseases in the population of Farmgate slum of Dhaka city. The study has been carried out to assess the present conditions of the water supply, water-borne disease, treatment pattern, sanitation, and their overall knowledge ab...