Maytham Abdulkadhim DraghUniversity of Misan · Biology Department
Maytham Abdulkadhim Dragh
Ph.D . Genetic Engineering & Cell Signaling / Huzhaing University of Life Science and Technology. HUST China
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31
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Introduction
Maytham Dragh currently works at the Biology Department, Misan University. Maytham does research in Genetics, Molecular Biology and Cell Biology. Their current project is 'Vitamin k2 prevents lymphoma in drosophila'.
Publications
Publications (31)
Introduction: A systematic library of Gal4/UAS-regulated transgenes has proven to be a powerful genetic system for identifying genes and defining pathways in development. This system offers valuable insights that highlight the evolutionary conservation between animals and humans. Objectives: The objective of this study was to clone, express, and ch...
The emergence of breast cancer (BC) patients could be influenced by common polymorphisms in the ABCG2 gene which impact chemotherapeutic response. Reactive oxygen species (ROS) and altered redox conditions are two prevalent biochemical features that might be linked to cytological changes in breast cancer (BC) patients. This case-control study compa...
The current study was conducted in Misan Governorate to detect the parasite Sarcocystis spp. by both conventional and molecular methods and to identify the species of this genus in goats as intermediate hosts for multiple species of this parasite. Regarding to the traditional study, the rates of infection with the macroscopic type of Sarcocystis sp...
ABSTRACT Sufficient intake of protein-enriched food is essential for all to maintain healthy lifestyle. The study targets to find out the Percentage of Protein in some available foods that are consumed daily by people of different incomes and ages. The chromatographic assay was done to explore the percentage of protein content in the food sources....
The problem of this study came in the lack of scientific research that dealt with the topics of the studied phenomenon, namely the energy index, which we find among the very important variables in the field of energy production for humans in general and athletes in particular, and the study aimed to identify the energy levels represented by (ATP) a...
Thalassemia is an autosomal recessive disorder. It occurs due to mutationsthat lead to a decrease or absence of β-globin chains. In human erythroid cells,it was found that BCL11A acts as a crucial factor for the silence of the γ-globingene and can decrease fetal hemoglobin (HbF) while promoting adulthemoglobin (HbA). This study was designed to eval...
Thalassemia Autosomal recessive disorders occur due to mutations that lead
to a decrease or absence of b-globin chains because mutations occur in the
BCL11A gene being a potential therapeutic target to increase fetal hemoglobin
levels in patients to reduce the severity of thalassemia symptoms. The study
was designed to evaluate the relationship...
Thalassemia Autosomal recessive disorders occur due to mutations that lead to a decrease or absence of b-globin chains because mutations occur in the BCL11A gene being a potential therapeutic target to increase fetal hemoglobin levels in patients to reduce the severity of thalassemia symptoms. The study was designed to evaluate the relationship bet...
The current study was conducted in Misan Governorate to detect the parasite Sarcocystis spp. by both conventional and molecular methods and to identify the species of this genus in goats as intermediate hosts for multiple species of this parasite. Regarding to the traditional study, the rates of infection with the macroscopic type of Sarcocystis sp...
This study aimed to determine and identify Sarcocystis spp. infection in sheep and goats in Misan governorate, Iraq. samples from oesophagus, diaphragm, tongue, and heart muscles were examined histologically for microscopic and macroscopic cyst , 70 out of 90 sheep 77.78 % had microscopic thick walled sarcocysts with mean 53 ×24.72 μm diagnosed as...
Breast cancer is a heterogeneous disease regarding its morphology, invasive behavior, metastatic capacity, hormone receptor expression and clinical outcome. Many risk factors for breast cancer, including genetic factors, account for 25-30% of the incidence. About 15-30% of breast cancer is heritable due to known familiar highly penetrates genes and...
Breast cancer is a heterogeneous disease regarding its morphology, invasive behavior, metastatic capacity, hormone receptor expression and clinical outcome. Many risk factors for breast cancer, including genetic factors, account for 25-30% of the incidence. About 15-30% of breast cancer is heritable due to known familiar highly penetrates genes and...
Breast cancer is one of the most aggressive cancers with high estimated mortality worldwide; many studies around the world have involved polymorphisms in drug resistance genes, tumor suppressor genes, estrogen receptor genes, and regulatory genes related to the development and prognosis of breast cancers. It is worth noting that this study was the...
Background: Breast cancer is a heterogeneous disease regarding its morphology, invasive behaviour, metastatic capacity, hormone receptor expression and clinical outcome. There are many risk factors for breast cancer, including genetic factors that account for 25-30% of the incidence; from this percentage, only 15-30% of the heritable component of b...
Blood samples were collected from ten pregnant goats every two weeks for the period of March-August, and blood serum was extracted for using analysis of albumin and cholesterol. The results showed that levels of albumin were gradually decreased with the progress of pregnancy while cholesterol levels remained about normal rates compared to non-pregn...
The objective of the study is to determine the genetic diversity between the most predominant Iraqi sheep breeds, Arrabi stands for southern breeds and Karradi stands for northern breeds. RAPD (Random Amplified Polymorphic DNA) were used in this study. A total of 40 blood samples were collected using 8 primers. All the primers showed polymorphism a...
The establishment of modern sheep production systems in Iraq, lead to presence of various forms of hybridization between the native and Middle East breeds which have been utilized for genetic improvement. This occur in consistence with the progressive destruction or deterioration of sheep habitat. Together, these factors have accelerated the loss o...
Zinc oxide nanoparticles (ZnO NPs) have acquired large attention against microbial activity because of their distinctive properties associated with their size and shape. In current research, ZnO NPs produced by the Sol-gel method at room temperature were applied to evaluate its antibacterial activity against pathogenic bacterial strains of Staphylo...
Zinc oxide nanoparticles (ZnO NPs) have acquired large attention against microbial activity because of their distinctive properties associated with their size and shape. In current research, ZnO NPs produced by the Sol-gel method at room temperature were applied to evaluate its antibacterial activity against pathogenic bacterial strains of Staphylo...
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) plays a key role in biosynthesis of vitamin K2 and coenzyme Q10 using geranylgeranyl diphosphate (GGPP). However, the mechanism by which UBIAD1 participates in tumorigenesis remains unknown. This study show that UBIAD1 interacts with H-Ras, retains H-Ras in the Golgi apparatus, prevents H-...
This study was conducted in the genetic engineering laboratory/ biology department/ college of science/Misan University.
Three primers (OPA-16, OPB-08, OPF-05 ) were applied in this study, all of which showed polymorphism, the highest polymorphism was with the primer OPA-16 which reached to 85% while the primer OPF-05 showed the lowest polymorphism...
Abstract: Genetic structure of Iraqi buffalo population, in the South, Middle and North area of the country was characterized, using six microsatellite markers (ETH152, ETH02, ETH225, CSSM060, BM1706 and INRA005). Seventy alleles were detected across the six loci. Total number of alleles per locus (TNA) varied from 3 (INRA005 locus) to 16 (ETH152 l...
Petroleum hydrocarbons (PHs) are a big group of chemicals that have caused a major concern because of their widespread distribution into the environment, bioaccumulation potential, harmful effects and biodegradation resistance. Soil and water pollution is mainly attributed to hydrocarbons from oil refineries, petrochemical industries, human activit...
Previous studies have established the sex determination technique using an amplification of Y chromosome specific fragments by PCR. However, most of these studies depended on rather complicated and extensive samples such as amniotic fluid or embryonic membrane smear, therefore, our study aimed to simplify this technique by replacing samples with si...
Previous studies have established the anticancer effect of vitamin K2 (VK2). However, its effect on lymphoma induced by UBIAD1/heix mutation in Drosophila remains unknown. Therefore, we aimed to develop an in vivo model of lymphoma for the precise characterization of lymphoma phenotypes. We also aimed to improve the understanding of the mechanisms...
In our study, conducted in Iraq and Huazhong University, China, divided Iraq into three main regions: a southern area including Basrah, Missan, and Dhi-Qar, a middle area including Al-Qadisiyah, Babil, Karbala and Baghdad, and a northern area including Diyala, Kirkuk and Mosul. The aim of the study was to measure the genetic diversity, polymorphism...