Mayank Priyadarshi

All India Institute of Medical Sciences Rishikesh · Department of Neonatology

Background Neonatal resuscitation guided by the Neonatal Resuscitation Program (NRP) algorithm is a frequently performed event. However, strict adherence to the algorithm is often lacking. This quality improvement study was conducted when we identified poor compliance with the NRP algorithm in the ‘initial steps’ as a problem in our hospital. Meth...

This report describes a newborn with a congenital melanocytic nevus (CMN) over the scalp, which gave a striking appearance of an Ascot cap. Though CMN are common, their location gives a unique look and associated findings (dermatological lesions like satellite lesions, café-au-lait spots, Mongolian spots, etc.) are often underappreciated in clinica...

Feed intolerance is a common problem in preterm and growth-restricted neonates, which can be caused by numerous etiologies. The exact etiology can be ascertained based on clinical presentation, timing of onset, course of illness, laboratory parameters and/or radiological investigations. We report a 29-week preterm neonate treated for necrotising en...

Objective The present study evaluated the correlation of Neonatal Infant Pain Scale (NIPS) and Premature Infant Pain Profile-Revised (PIPP-R), with changes in cerebral oxygenation (ΔcrSO2; measured by near-infrared spectroscopy) in preterm infants during acute painful procedures (heel lance and venepuncture). Study design Prospective observational...

Background: Infant massage is commonly practiced in many parts of the world. However, the effectiveness of this intervention has not been reviewed for term, healthy newborns. Methods: This systematic review of randomized and quasi-randomized controlled trials assessed the effect of whole-body massage with or without oil, compared to no massage i...

Background: This systematic review of intervention trials and observational studies assessed the effect of delaying the first bath for at least 24 hours after birth, compared to conducting it within the first 24 hours, in term healthy newborns. Methods: We searched MEDLINE via PubMed, Cochrane CENTRAL, Embase, CINAHL (updated till November 2021)...

Introduction COVID-19 and its mutants have significantly impacted the health care system, claiming numerous lives and adding to the morbidity. The data are scarce to describe the effect of disease severity on pregnancy outcomes, the possibility of mother-to-child transmission, and neonatal outcomes of COVID-positive babies. This study aimed to repo...

Background: This systematic review of randomized trials assessed the effect of emollient application compared to no emollient application in term or near-term healthy newborns. Methods: We searched MEDLINE via PubMed, Cochrane CENTRAL, Embase, and CINAHL (updated until November 2021), clinical trials databases, and reference lists of retrieved a...

Background: Though recommended by numerous guidelines, adherence to supine sleep position during the first year of life is variable across the globe. Methods: This systematic review of randomized trials and observational studies assessed the effect of the supine compared to non-supine (prone or side) sleep position on healthy newborns. Key outco...

In settings with adequate coverage of anti-D immunoglobulin, minor blood group incompatibility has become an important cause of hemolytic disease of the newborn (HDN). We presented a series of cases of HDN of varying severities caused due to presence of anti-E and anti-C antibodies. Two neonates with anti-E antibodies developed jaundice requiring i...

Objective: To determine whether heated humidified high-flow nasal cannula (HHHFNC) is noninferior to NCPAP to provide DR respiratory support to preterm neonates of gestational age (GA) 28-36 wk. Methods: This randomized, controlled, noninferiority trial included 124 spontaneously breathing preterm neonates who developed respiratory distress soon...

The aim of this prospective observational study was to compare the incidence of endotracheal tube (ETT) malposition using weight-based (Tochen), gestation-based (Kempley), and nasotragal length (NTL) methods in deceased neonates and fresh stillbirths. We enrolled deceased neonates and fresh stillbirths within 2 ± 1 h of death or delivery, respectiv...

Mother is the major source of minerals in foetal life with placenta actively transporting against a concentration and electrochemical gradient. The foetal serum mineral concentration is thereby higher as compared to maternal values, which possibly help in its rapid accretion in developing bones and for counteracting postnatal fall in calcium levels...

An antenatally diagnosed case of congenital diaphragmatic hernia (CDH) developing chylothorax following surgical repair is being reported. This report highlights the importance of fat-free diet in the form of skimmed milk in the medical management of post-operative chylothorax.

A preterm (30 ⁺² week) neonate with below-knee amputation (right lower limb), constriction rings and syndactyly, subsequent to amniotic band sequence, developed pus discharge from the right tibial stump. The neonate did not have clinical features of systemic sepsis. Blood culture was sterile. The pus culture, however, grew methicillin-resistant coa...

Objectives: Most authorities recommend daily supplementation of 400 IU vitamin D for all term healthy neonates throughout infancy, however this dose was shown to be inadequate in an earlier study from our institution. We planned to evaluate if supplementation of 800 IU/day in term Indian infants would reduce the prevalence of vitamin D insufficien...

A male infant (weight 2,340 g) is born to a 39-year-old gravida 2 woman with previously diagnosed systemic lupus erythematosus and a history of 1 preterm intrauterine fetal demise, at 34 weeks of gestation.

Cystic fibrosis (CF), an autosomal recessive disease with multi-system involvement, may present with bleeding in infancy owing to vitamin K malabsorption. Infantile tremor syndrome (ITS) is an obscure condition associated with vitamin B12 and other micronutrient deficiencies, described predominantly in Indian subcontinent. We describe an infant pre...