May Chun Mei Wong

• Doctor of Philosophy
• Professor (Associate) at The University of Hong Kong

Objectives A four‐dimensional structure for oral health‐related quality of life (OHRQoL) was recently proposed, comprising oral function (OF), orofacial pain (OP), orofacial appearance (OA) and psychosocial impact (PI). This study examined the impact of different temporomandibular disorder (TMD) symptoms on the four OHRQoL dimensions in young adult...

Background The Depression, Anxiety, Stress Scales-21 (DASS-21) contain three subscales measuring depression, anxiety, and stress. Several abbreviated DASS-21 versions have been developed, demonstrating better clinical utility and measurement properties than the original instrument. This study explored the factor structure of various abbreviated DAS...

Background: This is an update of a review first published in 2010. Use of topical fluoride has become more common over time. Excessive fluoride consumption from topical fluorides in young children could potentially lead to dental fluorosis in permanent teeth. Objectives: To describe the relationship between the use of topical fluorides in young...

Objectives The rapidly ageing world has placed considerable demands on health and social care. To address this, the World Health Organization (WHO) and United Nations (UN) have declared action for this decade (2021–2030) to promote healthy ageing. Operationalisation of successful ageing in the oral health context in terms of its dimensions and thei...

Well-designed high-quality randomized controlled trials (RCTs) provide scientific evidence for clinical practitioners to provide the appropriate care for their patients. In this chapter, published RCTs in pediatric dentistry are reviewed. A wide range of topics has been covered in the RCTs in the literature. However, knowledge gaps between the pres...

Background Positive bone margins have been shown to be associated with worse locoregional control and survival performance in oral oncology patients. With the application of computer-assisted surgery (CAS) and patient-specific surgical guides, we can accurately execute the preoperative osteotomy plan. However, how well we can predict the margin dis...

Background/purpose World Health Organization (WHO) oral health survey manual is the main guideline for most oral health surveys worldwide. It has been updated several times since 1971; however, using papers and pens for data recording remains unchanged. This study aimed to develop the Vietnam Oral Survey Electronics Recorder (VOSER) to record denta...

Background Due to some unique physical, social and psychological features in the adolescent population, adolescents can be a time of heightened caries activity and periodontal disease. Oral health-related behaviors can be modified to improve oral health status. The family networks and the built environment can promote or inhibit health behaviors. T...

Importance Platelet transfusion is commonly performed in infants to correct severe thrombocytopenia or prevent bleeding. Exploring the associations of platelet transfusion, platelet count (PC), and mean platelet volume (MPV) with intraventricular hemorrhage (IVH) and in-hospital mortality in preterm infants can provide evidence for the establishmen...

Objective This systematic review evaluated the effectiveness of oral health education using mHealth approach to parents for improving their children's oral health. Data Twelve studies were included after the screening and five studies in the data synthesis. The sample size varied from 34 to 1055. There was a very low level of evidence showing that...

Objective : To investigate the short-term and long-term changes in parental satisfaction and oral health-related quality of life (OHRQoL) of preschool children after receiving atraumatic restorative treatment (ART) with or without prior silver diamine fluoride (SDF) application. Method : In a randomized controlled trial, preschool children with ca...

Background It has been recognized that oral health education for parents is critical for preventing early childhood caries (ECC). Few parents practiced caries prevention procedures for their children in daily life, though. A novel intervention scheme using mobile messages will be developed in this study under the framework of the health belief mode...

Objective The objective of this study is to investigate the effectiveness of motivational interviewing (MI) in changing health behaviors (snack and toothbrushing) and preventing dental caries among adolescents.Methods Five hundred and twelve adolescents with unfavorable caries-related behaviors (“snacking three times or more a day” and/or “toothbru...

Background Computer-assisted jaw reconstruction (CAJR) has benefits in reducing operation time and improving reconstruction accuracy, compared to conventional freehand jaw reconstruction. However, no information is available regarding learning curves in CAJR with the use of 3D-printed patient-specific surgical plates (PSSP). The purpose of this stu...

Early childhood caries is common in Hong Kong, and parental practices on maintaining good oral health of their young children are far from satisfactory. This article reports on the effectiveness of a randomized controlled trial on family-centered oral health promotion to new parents in establishing proper feeding habits and oral hygiene practices a...

Background : Randomized controlled trials (RCTs) in dentistry provide essential evidence for dentists to practice evidence-based dentistry. This study aimed to analyze the scientific impacts of the RCTs conducted among children and adolescents published in dental journals and summarize the main contents of these studies. Methods : An electronic li...

Objectives This study examined the metric properties of the Oral Health Impact Profile for Temporomandibular Disorders (OHIP-TMD) using Factor/Rasch analyses and created a short-form version of the measure. Subjects and Methods Aggregated OHIP-TMD data were obtained from a cross-sectional study involving 844 TMD patients with Diagnostic Criteria f...

Background: It has been recognized that oral health education for parents is critical for preventing early childhood caries (ECC). Few parents practiced caries prevention procedures for their children in daily life, though. A novel intervention scheme using mobile messages will be developed in this study under the framework of the Health Belief Mod...

Aim To provide a dynamic description of the oral microbial composition in mothers with and without dental caries and their children aging 12-24 months. Methodology A total of 20 pairs of mothers and their children aged 12 months were included and followed up at 18 and 24 months of age. Ten mothers with dental caries(MEG) and their children(CEG) we...

Background: The effective control of moisture and microbes is necessary for the success of restoration procedures. The rubber dam, as an isolation method, has been widely used in dental restorative treatments. The effects of rubber dam usage on the longevity and quality of dental restorations still require evidence-based discussion. This review co...

Abstract Background This longitudinal study aimed to evaluate the longitudinal validity and reliability of the Oral Health Impact on Daily Living (OHIDL) transition scale and measure the perceived change in oral health-related quality of life (OHRQoL) after dental treatments among older adults. Methods OHIDL was administered to older adults who sou...

Objectives: To investigate the associations between dental conditions, sliver diamine fluoride (SDF) application, parental satisfaction, and oral health-related quality of life (OHRQoL) of preschool children. Materials and methods: In a clinical trial conducted in Hong Kong, preschool children who had carious lesions into dentine were randomly a...

Objectives Aim of this systematic review was to summarize the factors that affect the success rate of atraumatic restorative treatment (ART) restorations in children. Data/Sources Two independent reviewers conducted a literature search in the databases PubMed, Medline and Web of Science until October 2019 with no initial time limit. Articles repor...

Objectives Computer assisted head and neck reconstruction has gained popularity over the past few years. In computer assisted surgery (CAS), surgical margins are predetermined in virtual surgery and resection guides are designed to be fitted intra-operatively. However, concerns have been raised regarding the oncological safety of predetermined surg...

Objective The aim of this randomised non-inferiority clinical trial was to compare the effectiveness of semi-annual (every six months) applications of 25 % silver nitrate (AgNO3) solution followed by 5 % sodium fluoride (NaF) varnish to semi-annual applications of 38 % silver diamine fluoride (SDF) solution in arresting early childhood caries (ECC)...

Background: The novel pandemic of coronavirus disease 2019 (COVID-19) has posed a public health crisis across the globe. Healthcare professionals, including dental practitioners, are thus anticipated to face the new challenges regarding infection control and clinic operation. Aims: This project set out to investigate the impacts of the COVID-19 o...

Abstract Background Poor oral hygiene and high hormone levels during pregnancy can lead to a deterioration in periodontal health. This study assessed the effectiveness of a family-centered behavioral and educational counselling program on improving the periodontal health of women during pregnancy and postpartum. Methods A randomized controlled tria...

Objective: To compare the success rates of restoring untreated and SDF-treated dentine caries lesions in primary teeth with atraumatic restorative treatment (ART) approach. Method: Cavitated dentine caries lesions in preschool children were randomly allocated to two groups to be applied with either 38% silver diamine fluoride (SDF) solution or to...

Objective To compare the success rates of restoring untreated and SDF-treated dentine caries lesions in primary teeth with atraumatic restorative treatment (ART) approach. Method Cavitated dentine caries lesions in preschool children were randomly allocated to two groups to be applied with either 38% silver diamine fluoride (SDF) solution or tonic...

Background Surgeons are pursuing accurate head and neck reconstruction to enhance aesthetic and functional outcomes after oncologic resection. This study aimed to investigate whether accuracy of head and neck reconstruction is improved with the use of three-dimensionally (3D)-printed patient-specific surgical plates compared with conventional plate...

Objective The present case‐control study aims to compare the psychological status of patients with and without halitosis, and investigate the association of psychological disorders and halitosis. Methods Patients who complained about bad breath and diagnosed with genuine halitosis were assigned to the halitosis group, while patients without genuin...

Objectives: Poor oral hygiene and higher hormone levels during pregnancy always lead to poor periodontal health. Oral health education of the pregnant women to improve the periodontal outcomes might be ineffective and inconsistent. The aim of this study was to assess the effectiveness of a family-centered behavioral and educational counselling prog...

Background: This community-based study investigated the functional, physical and psychosocial impact of Temporomandibular Disorders (TMDs) in adolescents and young adults. It also determined the discriminative capacity of a TMDs-specific oral health related quality of life (OHRQoL) instrument and compared three formats of appraising OHRQoL data....

Objectives: To investigate the success rate of restoring untreated and SDF-treated dentine caries lesions in primary teeth through atraumatic restorative treatment (ART) approach. Methods: After having obtained parental consent, preschool children with cavitated dentine caries lesions in their primary teeth were randomly allocated to two groups to...

Background Children’s oral health status (OHS) can be influenced by their oral health practices and many parental factors. This study aimed to investigate pathways from parental factors to oral health practices and status of children in Hong Kong. Methods Using a combination of random and purposive sampling of Hong Kong households, 432 families wi...

Abstract Background Silver diamine fluoride (SDF) solution gains increasing popularity in arresting dentine caries in clinical practice. The aim of this systematic review was to summarize the findings from laboratory studies on the influence of SDF application on the bond strength of dentine to various adhesives and to glass ionomer cements (GICs)....

Background: Silver diamine fluoride (SDF) solution is effective in arresting early childhood caries (ECC). Previous studies have suggested that it might exert a preventive effect in managing ECC. However, no well-designed clinical trials have yet been performed to study the effect of SDF on caries prevention. The objective of this randomised clini...

Objectives: The aim of the present superiority study was to determine the effect of systemic antibiotics primarily on patient reported outcome measures (PROMs) and post-surgical complications in patients undergoing oral implant therapy with simultaneous guided bone regeneration (GBR). Materials & methods: 236 medically and periodontally healthy...

Objective To assess self-reported general health (SRGH) and self-reported oral health (SROH), and to identify factors associated with these self-health reports among adults in the United States. Methods Data from the National Health and Nutrition Examination Survey (NHANES) for 1999 to 2014 were analyzed. Survey-weighted descriptive statistics wer...

Objectives: To find out the effects of placement of atraumatic restorative treatment (ART) restorations on parental satisfaction and oral health related quality of life (OHRQoL) of preschool children with SDF-treated or untreated dentine caries lesions. Methods: In a randomized controlled trial conducted in Hong Kong, preschool children who had...

Background: Pregnant women are at risk of oral health problems. This qualitative study aims to understand dental care-seeking behaviours of pregnant women and their oral health-related information acquisition, to identify barriers to and motivators for, dental visits, and further explore their expectations and possible strategies to improve oral h...

Objectives: To identify the risk predictors of root caries and to describe their relationship with the incidence and increment of root caries. Data: Observational longitudinal studies. Sources: Four electronic databases (PubMed, MEDLINE, EMBASE, and Scopus) (From 1 January 1990 to 31 January 2019). Study selection: Information on the factors...

Background: The Oral Health Impact on Daily Life Questionnaire (OHIDL) was developed through a qualitative study to measure oral health-related quality of life, including intensity and bother measurements, among older adults in Hong Kong. The instrument comprises 20 items divided into eight domains. Objectives: This study describes the psychomet...

Objectives: To study the effect of placement of atraumatic restorative treatment (ART) restoration on parental satisfaction and oral health-related quality of life (OHRQoL) of preschool children with untreated or SDF-treated dentin caries lesions. Methods: In a clinical trial conducted in Hong Kong, children aged 3-4 years who had cavitated dentin...

Objectives: The objectives of this review were to identify the factors associated with root caries and to describe their relationship with the presence and extent of root caries. Methods: A search was carried out on the PubMed, Medline, Embase, and Scopus databases for articles published between January 1990 and October 2018. Information was ext...

Objectives The aim was to assess the anatomical relationship of anterior maxillary teeth to the nasal floor in patients referred for apical surgery. Materials and methods Cone beam computed tomographic images (CBCT) of 83 patients were analysed retrospectively to quantify the distances between the root apices of maxillary anterior teeth (canine to...

Objectives: The aim of this noninferiority double-blind randomized clinical trial was to compare the effectiveness of the topical semiannual application of a 25% silver nitrate (AgNO3) solution followed by a 5% sodium fluoride (NaF) varnish with that of a 38% silver diamine fluoride (SDF) solution in arresting caries among preschool children. Met...

Abstract Background A number of studies on oral microbial diversity of early childhood caries (ECC) have tended to focus on mid- or late-stage of ECC, with a lack of research into early stage of tooth eruption and maternal influence. The aims of this study are to compare the supragingival plaque biofilm microbiota diversity between mothers with or...

A cohort study was conducted to evaluate oral microbial diversity among toddlers aged 12–24 months, and to describe the dynamic processes of colonization, development, and stabilization of the oral microflora during tooth eruption using high-throughput sequencing technology. A total of 20 healthy toddlers aged 12 months were included at baseline an...

Quality control of the sequencing. (A) The rarefaction curves. (B) The species accumulation curves. (C) The abundance distribution curves.

UniFrac The cross ordinates correspond to the statistical comparisons between groups, and the longitudinal coordinates indicate the corresponding distance values.

Classification and compositional ratios of the samples obtained the three time points sequenced at the taxonomic level.

Background: Programmed death-ligand 1 (PD-L1) is an immune checkpoint that is primarily located on the surface of tumor cells. PD-L1 expression detected by immunohistochemistry (IHC) assays has been widely studied to predict survival outcomes in head and neck squamous cell carcinoma (HNSCC) recently. We aimed to review comprehensively the prognost...

Objectives: Topical application of silver diamine fluoride (SDF) solution is effective in arresting active dentin caries in primary teeth of children but the arrested caries lesions are usually stained black in color. Objective of this study was to describe parental satisfaction with the aesthetics of their child’s decayed primary anterior teeth re...

Background: Longitudinal invariance is a perquisite for a valid comparison of oral health-related quality of life (OHRQoL) scores over time. Item response theory (IRT) models can assess measurement invariance and allow better estimation of the associations between predictors and latent construct. By extending IRT models, this study aimed to invest...

This randomized clinical trial aimed to compare the adverse effects and parental satisfaction following the different regimes of silver diamine fluoride (SDF) treatment among preschool children. A total of 888 preschool children who had active dentin caries received different SDF application regimes: group 1, 12% SDF applied annually; group 2, 12%...

Objective: To compare the effectiveness of three applications of silver diammine fluoride (SDF) solution at yearly interval and three applications of SDF solution or sodium fluoride (NaF) varnish at weekly interval at baseline in arresting active caries in the primary teeth of preschool children. Methods: Children aged 3-4 years (n = 371) who ha...

Oral epidemiology involves studying and investigating the distribution and determinants of dental-related diseases in a specified population group to inform decisions in the management of health problems. In oral epidemiology studies, the hypothesis is typically followed by a cogent study design and data collection. Appropriate statistical analysis...

This 30-mo randomized clinical trial compared the effectiveness of 2 concentrations (12% or 38%) of silver diamine fluoride (SDF) and 2 periodicity of application (once or twice a year) in arresting cavitated dentin caries in primary teeth. Children aged 3 to 4 y who had at least 1 active cavitated caries lesion were enrolled and randomly allocated...

Background: To explore and better understand how patients evaluate satisfaction in dental care and elicit information from them to develop a dental satisfaction instrument. Methods: Patients currently receiving dental treatment in a teaching hospital were invited to be part of a qualitative research project which involved focus group discussion....

The aim of this systematic review was to address the question: Do different irrigating protocols have an impact on the dislocation resistance of mineral trioxide aggregate (MTA)- based materials? The review was performed using a well-defined search strategy in three databases (PubMed, Scopus, Web of Science) to include laboratory studies performed...

Objective: Single-item self-reported oral health (SROH) is a convenient and reliable measure for the assessment of population-based oral health. However, little is known about trends and its associations among US adults. This study investigated trends in SROH (aged 20+ years) and the associated factors among adults living in the United States. Me...

Objective Previous studies have found that herpesviruses are associated with aggressive periodontitis (AgP). However, these findings are controversial. This meta-analysis was aimed at clarifying the association between herpesviruses and AgP. Methods We identified eligible case–control studies evaluating the association between herpesviruses and Ag...

Electronic search strategy of PubMed database. (DOCX)

Quality score assessment. (DOCX)

Articles excluded after critical appraisal. * with systematically diseases: Patients with systemic diseases or infections. # Undefined diagnosis: The diagnosis of patients is not appropriate or not clear. ^ No case-control design: Study is not design as case-control style. (PDF)

Aim: This 30-month randomized clinical trial compared the effectiveness of two concentrations (12% or 38%) of SDF and different periodicity of application (once or twice a year) in arresting cavitated dentin caries in preschool children. Design: Children aged 3–4 years with active cavitated caries were allocated into four groups for intervention....

Purpose The current cross-sectional study aimed to investigate risk factors for dysphagia in elderly individuals in aged care facilities. Method A total of 878 individuals from 42 aged care facilities were recruited for this study. The dependent outcome was speech therapist-determined swallowing function. Independent factors were Eating Assessment...

Introduction: Professional burnout has been described as a gradual erosion of a person and may be one of the possible consequences of chronic occupational stress. Although occupational stress has been surveyed among dentists in Hong Kong, no study has been published about burnout in the profession. This study aimed to evaluate burnout among Hong K...

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of silver diamine fluoride in arresting and preventing caries in deciduous and permanent teeth (coronal and root caries) compared to any other intervention including placebo or no treatment.

Purpose: Motivational interviewing (MI) is a counseling strategy to help people change their behaviors. This single-blinded randomized controlled trial evaluated the effectiveness of MI in improving adolescents' oral health. Methods: Fifteen secondary schools were randomly assigned to three groups: (I) prevailing health education, (II) MI, and (...

Dental root caries is a common disease among elders. More efforts on preventing this disease are needed. Silver diammine fluoride (SDF) is known to prevent dental caries in primary teeth. However, clinical evidence of its efficacy in preventing root surface caries is limited. This clinical trial aimed to compare the effectiveness of SDF in preventi...

Objective: To develop an instrument to measure Oral Health-related Quality of Life (OHQoL) and the changes after dental treatment among older adults in Hong Kong, in order to understand their views on the influences of oral health problems and generate relevant items to design the instrument. Methods: A qualitative study was conducted among adul...

Background: Successful restorations in dental patients depend largely on the effective control of moisture and microbes during the procedure. The rubber dam technique has been one of the most widely used isolation methods in dental restorative treatments. The evidence on the effects of rubber dam usage on the longevity of dental restorations is co...

Objectives: To investigate the effectiveness of silver diammine fluoride (SDF) solution application in arresting dental root caries and to assess the color of arrested caries lesions. Methods: This study was conducted in elderly centers in Hong Kong. A total of 83 elders with 157 root surfaces with active caries lesion were randomly allocated in...

Objectives: This study aimed to compare the effectiveness of three topical fluoride application protocols in arresting dental caries in primary teeth of preschool children. Methods: A total of 371 children aged 3-4 years who had at least one active caries lesion in their primary teeth were randomly allocated into three intervention groups: Group 1...

Different regimens of silver diamine fluoride (SDF) have been used to manage early childhood caries. So far, there is limited information regarding the concentrations and frequency of applications for effective caries control in primary teeth. This study aimed to compare the efficacy of 2 commercially available SDF solutions at preprepared concentr...

Objectives: This study aimed to assess the pathways from modifiable risk factors to oral health status in husbands and wives, and correlation in oral health KAP and status between married couples in Hong Kong. Methods: This was a cross-sectional survey using a combination of random household and purposive sampling. Socio-economic status (SES), s...

Numerous studies have investigated the associations between herpesviruses and chronic periodontitis; however, the results remain controversial. To derive a more precise estimation, a meta-analysis on all available studies was performed to identify the association between herpesviruses and chronic periodontitis.A computerized literature search was c...

PRISMA Checklist. (DOC)

Four-factor structure of the two 8-item short forms of Child Perceptions Questionnaire CPQ11-14 (RSF:8 and ISF:8) has been confirmed. However, the sum scores are typically reported in practice as a proxy of Oral health-related Quality of Life (OHRQoL), which implied a unidimensional structure. This study first assessed the unidimensionality of 8-it...

Introduction Geriatric dysphagia is becoming an increasingly needful area as the population ages across many countries. Aged care staff and caregivers for the elderly are often ill equipped to deal with swallowing difficulties as there is limited knowledge of the occurrence and risk factors in this population and setting. This study aimed to identi...

Background: The application of 38 % silver diamine fluoride (SDF) has been shown to be effective in arresting early childhood caries (ECC). Since SDF is not available in certain countries, some dentists use adjunctive application of 25 % silver nitrate (AgNO3) and 5 % sodium fluoride (NaF) to arrest ECC. This randomised controlled trial will syste...

Objectives: To describe the effectiveness of applications of silver diammine fluoride (SDF) solution in preventing root caries among elders in Hong Kong. Methods: This study was conducted on community-dwelling elders aged over 55 years in Hong Kong. Elders who had at least 5 teeth with exposed root surfaces and had self-care ability were randomly...

Background Studies have been rarely conducted to provide a comprehensive perspective of pregnant women with the intention to investigate the relationships between periodontal conditions and oral health-related quality of life (OHRQoL). As such, this study aimed to describe the OHRQoL of pregnant women in Shanghai, China and to investigate the relat...

To investigate the prevalence and severity of tooth wear (TW) and its relationship with consumption of beverages among adults in the United States. The National Health and Nutrition Examinations Survey data for 2003-2004 was analyzed. TW was defined as "wear on at least one surface of at least one examined tooth." Drink/juice consumption was ascert...

Background: Swallowing problems in elderly may lead to poor quality of life and higher chance of hospitalisation because of aspiration pneumonia, malnutrition and dehydration. The current study aims to 1) document the prevalence and impact of swallowing problems in elderly; 2) determine the carers’ knowledge in swallowing management; and 3) evaluat...

Objective: We investigated the prevalence of erosive tooth wear (ETW), juice/drink consumption and associated factors in adults in the United States. Methods: We used the National Health and Nutrition Examinations Survey data for 2003-2004. ETW is defined as erosive tooth wear on at least one surface of at least one examined tooth. Drink/juice co...

Objective: To investigate the change in perceived oral health impacts on daily living after dental treatment using Oral Health Impact on Daily Living Questionnaire (OHIDL). Method: Data was collected through OHIDL, which was developed to measure the perceived oral health impacts on daily living and their change. Older adults aged 55+ years were as...

Chronic orofacial pain (OFP) is common in general adult populations worldwide. High levels of psychological distress and impaired coping abilities are common among Western people with chronic OFP but limited information was found in southern Chinese people. This study aimed to explore the perceptions and experiences of community dwelling elderly pe...

To assess the oral health-related quality of life (OHRQoL) of young adults in Hong Kong and its relationships with oral health status. A survey was conducted in a representative sample of Hong Kong adults aged 18 years. OHRQoL was measured by the short form Oral Health Impact Profile (OHIP-14, Chinese version). Clinical examinations were taken to a...