Maximilian Thormann

Maximilian Thormann
Otto-von-Guericke-Universität Magdeburg | OvGU · Clinic for Radiology and Nuclear Medicine, Clinic for Neuroradiology

Doctor of Medicine

About

38
Publications
1,402
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25
Citations
Citations since 2017
37 Research Items
24 Citations
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201720182019202020212022202305101520

Publications

Publications (38)
Article
Aim: This study aimed at assessing body composition measurements, creeping fat (CrF), and Crohn's disease's (CD) activity based on the Magnetic Resonance Index of Activity (MaRIA). Methods: 114 CD patients who underwent magnetic resonance enterography (MRE) between June 2010 and April 2020 were retrospectively assessed. The semi-automated body c...
Article
Purpose: Image-guided interstitial high-dose-rate brachytherapy (iBT) has been demonstrated to offer high local tumor control rates (LTC) of >90% after local ablation of intermediate and advanced hepatocellular carcinoma (HCC; BCLC B and C). The purpose of this study was to show the efficacy of iBT stratified by subgroups and to identify clinical...
Article
Full-text available
Background Flow diverters are an increasingly used treatment option for intracranial aneurysms. A recent addition to the European market is the DERIVO®2 Embolization Device (DED2), promising improved radiopacity. We aimed to assess the safety and efficacy of the DED2 regarding angiographic and clinical outcomes in ruptured and unruptured cerebral a...
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Purpose Past research contained the investigation and development of robotic ultrasound. In this context, interfaces which allow for interaction with the robotic system are of paramount importance. Few researchers have addressed the issue of developing non-tactile interaction approaches, although they could be beneficial for maintaining sterility d...
Article
Rationale and Objectives Sarcopenia is defined as skeletal muscle loss and can be assessed by cross-sectional imaging. Our aim was to establish the effect of sarcopenia on relevant outcomes in patients with pancreatic ductal adenocarcinoma (PDAC) in curative and palliative settings based on a large patient sample. Materials and Methods MEDLINE lib...
Article
Background/aim: To assess the influence of pre-treatment apparent diffusion coefficient (ADC) measurements on outcomes in patients undergoing interstitial brachytherapy (iBT) for liver metastases from renal cell carcinoma. Patients and methods: Patients undergoing iBT for renal cell carcinoma (RCC) liver metastases were retrospectively identifie...
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Full-text available
Purpose Image-guided thermal ablation are established treatment options for non-surgical patients with primary and metastatic liver cancers. However, there are limitations with nonuniformity of cancer tissue destruction, heat sink effect and the risk of thermal ablative injury. The current non-thermal ablative techniques have high risk of local rec...
Article
Purpose Several studies report an association of sarcopenia with survival in oncologic patients. The aim of this study is to assess the influence of sarcopenia on overall survival (OS) in patients with colorectal liver metastases undergoing interstitial brachytherapy (iBT) Methods We identified 144 patients with colorectal liver metastases from our...
Article
Background: Interstitial brachytherapy (iBT) has become a viable treatment option in the therapy of early and intermediate stage hepatocellular carcinoma (HCC). Prognostic imaging tools to predict patient outcome are missing. Purpose: To assess the predictive value of baseline diffusion-weighted imaging in HCC before iBT with regard to local tum...
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Introduction Primary stereotactic radiosurgery for intraventricular meningiomas remains controversial due to the potential for life-threatening peritumoral edema and lack of long-term follow-up data. We review the literature and present the largest series to assess efficacy and safety of primary stereotactic radiosurgery. Methods A systematic revi...
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Purpose: To analyze relationships betweenapparent diffusion coefficient (ADC) and activity parameters of Crohn's disease, e.g., length and wall thickness, CRP, FCP, MaRIA, CDAI, SES-CD, histologic inflammatory activity score, and the histological fibrotic score, based upon published data. Materials and methods: MEDLINE library, Scopus, and Embas...
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Purpose: Sarcopenia has been identified as a prognostic marker of clinical outcomes in several diseases. However, the influence of sarcopenia on non-surgical local treatments in breast cancer liver metastases (BCLM) is unknown. Therefore, the purpose of this study was to assess the effect of sarcopenia among patients with BCLM undergoing interstit...
Conference Paper
Clinical history/pre-treatment-imaging We report a successful implantation of a peripheral stent in a dural arteriovenous fistula (dAVF) over a j-shaped 0.035” steel-wire (Rosen). The patient was a 61-year old male presenting with a known dAVF Cognard 2b in the right sigmoid sinus. The jugular vein was thrombosed intracranially. Treatment options/...
Conference Paper
Introduction Flow diverters have emerged as an effective and widely utilized therapy option for intracranial aneurysms. The DERIVO 2 Embolization Device (DED2) is a new addition to the market and promises better radiopacity.¹ Aim of study The purpose of this study was to evaluate the safety and efficacy of the DED2. Methods We conducted a retrosp...
Article
Full-text available
Low skeletal muscle mass as a proxy parameter for sarcopenia acts as a non-invasive imaging marker that is associated with poor prognosis in numerous types of cancer. The present study aimed to assess the influence of body composition parameters on overall survival (OS) and progression free survival (PFS) in patients diagnosed with primary central...
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Purpose To assess the influence of low skeletal muscle mass (LSMM) on post-operative complications in patients with hepatic malignancies grade (Clavien Dindo ≥ 3) undergoing resection. Methods MEDLINE, Cochrane, and SCOPUS databases were screened for associations between sarcopenia and major post-operative complications (≥ grade 3 according to Cla...
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Background Locoregional therapies, as imaging-guided tumor-directed procedures, are emerging treatment strategies in the management of primary and secondary liver malignancies such as e.g. colorectal cancer liver metastases. As one of those, irradiation-based interstitial high dose rate brachytherapy (iBT) of liver metastases bears a risk of develo...
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Full-text available
Zusammenfassung Kontaktbeschränkungen und Abstandsregeln haben die klinische Weiterbildung vor große Herausforderungen gestellt. Innovative und interaktive Konzepte sind notwendig, um die Weiterbildung auch in Zeiten von Corona aufrechtzuerhalten. In der aktuellen Literatur sind Lehrkonzepte für Ärztinnen und Ärzte in der Facharztweiterbildung jedo...
Article
Purpose: Image-guided brachytherapy with a single-fraction irradiation (high-dose-rate brachytherapy - HDR-BT) is a promising local ablation technique for unresectable liver metastases. The occurrence of needle track seeding after biopsy and microwave ablation (MWA) has been documented primarily in hepatocellular carcinoma (HCC). Comprehensive dat...
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Full-text available
Background&Aims Hepatocellular carcinoma (HCC) is the fifth most common malignant tumor disease in the world. The impact of sarcopenia on survival outcomes in patients with HCC has been studied, but the extent of the impact remains unclear. This systematic review and meta-analysis aimed to analyze the prevalence of low skeletal muscle mass (LSMM) a...
Article
Background Data on the frequency and outcome of mechanical thrombectomy (MT) for large vessel occlusion (LVO) in patients with COVID-19 is limited. Addressing this subject, we report our multicenter experience. Methods A retrospective cohort study was performed of consecutive acute stroke patients with COVID-19 infection treated with MT at 26 tert...
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Background: The importance of an A1 aplasia remains unclear in stroke patients. In this work, we analyze the impact of an A1 aplasia contralateral to an acute occlusion of the distal internal carotid artery (ICA) on clinical outcomes. Methods: We conducted a retrospective study of consecutive stroke patients treated with mechanical thrombectomy...
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Background/aim: The effect of sarcopenia on patients with severe Covid-19 disease is unknown. We aimed to assess the influence of baseline computed tomography (CT)-based body composition parameters (pectoralis muscle area, pectoralis muscle index, skeletal muscle gauge) on clinical variables in patients with severe Covid-19 disease. Patients and...
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Introduction : The grade of reperfusion after endovascular treatment of ischemic stroke e.g. mechanical thrombectomy is determined based on the mTICI score. The mTICI score shows significant interrater variability; it is usually biased towards better reperfusion results if selfassessed by the operator. We therefore developed a semiautomated image p...
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Background For wide-necked intracranial aneurysms, endo-saccular flow disruption can be a viable alternative to coiling or flow diverters. The Contour Neurovascular System is an intrasaccular flow diverter device targeting the neck of the aneurysm. Until now, the system had to be delivered through a 0.027″ microcatheter. We report the first implant...
Conference Paper
Introduction/Purpose The discrimination between hemodynamically stable and unstable intracranial aneurysms remains challenging. Recent studies reveal the potential existence of intra-aneurysmal velocity fluctuations, which appear at high frequency. Since these flow disturbances might promote the vessel wall remodeling process, indications regarding...
Conference Paper
Introduction/Purpose Interventional treatment of arteriovenous malformations (AVMs) using liquid embolics is challenging especially in larger AVMs with multiple feeding arteries. Premature occlusion of the draining vein(s) may lead to fatal AVM rupture and sequential occlusion of different feeding arteries is associated with the risks of incomplete...
Conference Paper
Introduction/Purpose Counseling of patients harboring unruptured intracranial aneurysms (UIAs) has remained challenging despite the availability of several risk scores assessing the aneurysm rupture risk for individual patients. However, besides aneurysm size and simple morphological features no advanced hemodynamic or geometric factors have been u...
Conference Paper
Introduction/Purpose Blebs of intracranial aneurysms are clear bulges or outpouchings of the aneurysms wall. Since irregularly shaped aneurysms, i.e. aneurysms with lobulated shapes including one or multiple blebs are associated with a higher rupture risk, bleb occurrence is important for aneurysm treatment planning. Hence, an automatic computer-ba...
Conference Paper
Full-text available
Background The mTICI score used to assess the degree of reperfusion after mechanical thrombectomy is an independent predictor of patient outcome after acute ischemic stroke. Its inter-rater reliability, however, is low and interventionalists often overrate their own performance.¹ Objectives We devised an image-processing based semi-automated gradi...
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Interdisciplinary exchange of medical datasets between clinicians and engineers is essential for clinical research. Due to the Data Protection Act, which preserves the rights of patients, full anonymization is necessary before any exchange can take place. Due to the continuous improvement of image quality of tomographic datasets, anonymization of p...
Article
When faced with illness, Sudanese patients have traditionally relied primarily on folklore healers. In the recent past, Sudan increased its health care spending and placed ever-greater importance on medical education. Although traditional remedies still play an important role, Sudanese patients increasingly consult conventional medicine. Not only i...
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Full-text available
The A1555G mutation in the 12S rRNA gene of human mitochondrial DNA causes maternally inherited, nonsyndromic deafness, an extreme case of tissue-specific mitochondrial pathology. A transgenic mouse strain that robustly overexpresses the mitochondrial 12S ribosomal RNA methyltransferase TFB1M (Tg-mtTFB1 mice) exhibits progressive hearing loss that...

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