Maxime Peralta

Université de Rennes 1 | UR1 · LTSI - Laboratoire Traitement du Signal et de l'Image

Deep Brain Stimulation (DBS) is an increasingly common therapy for a large range of neurological disorders, such as abnormal movement disorders. The effectiveness of DBS in terms of controlling patient symptomatology have made this procedure increasingly used over the past few decades. Concurrently, the popularity of Machine Learning (ML), a subfie...

PurposeDeep Brain Stimulation (DBS) is a proven therapy for Parkinson’s Disease (PD), frequently resulting in an enhancement of motor function. Nonetheless, several undesirable side effects can occur after DBS, which can worsen the quality of life of the patient. Thus, the clinical team has to carefully select patients on whom to perform DBS. Over...

Deep brain stimulation (DBS) is an interventional treatment for Parkinson's disease which involves the precise positioning of stimulated electrodes within deep brain structures, such as the Subthalamic Nucleus (STN). Although originally identified via imaging, additional inter-operative guidance is necessary to localize the target anatomy. Analysis...

Medical questionnaires are a valuable source of information but are often difficult to analyse due to both their size and the high possibility of having missing values. This is a problematic issue in biomedical data science as it may complicate how individual questionnaire data is represented for statistical or machine learning analysis. In this pa...

Deep Brain Stimulation (DBS) is a successful and encouraging way of treating abnormal movement diseases, such as Parkinson’s Disease (PD). The success of the surgical procedure depends on many variables, most of which are derivative from a great number of modalities. Various problems gravitate throughout the care of the pa-tient, from its screening...

Micro-electrode recording (MER) is a powerful way of localizing target structures during neurosurgical procedures such as the implantation of deep brain stimulation electrodes, which is a common treatment for Parkinson's disease and other neurological disorders. While Micro-electrode Recording (MER) provides adjunctive information to guidance assis...

Parkinson’s Disease provokes alterations of subcortical deep gray matter, leading to subtle changes in the shape of several subcortical structures even before the manifestation of motor and non-motor clinical symptoms. We used an automated registration and segmentation pipeline to measure this structural alteration in one early and one advanced Par...