Matthias Werchan

Matthias Werchan
Charité Universitätsmedizin Berlin | Charité · Stiftung Deutscher Polleninformationsdienst

Dipl. Landscape Ecologist

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45
Publications
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410
Citations

Publications

Publications (45)
Article
In Deutschland leidet fast jeder siebte Erwachsene an medizinisch diagnostizierter allergischer Rhinitis, die häufig durch eine Reaktion auf Pollen verursacht wird. Wie in anderen europäischen Ländern gibt es auch in Deutschland ein nationales Pollenmessnetz (Stiftung Deutscher Polleninformationsdienst (PID)), das die Pollen- und Pilzsporenkonzentr...
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Allergic rhinoconjunctivitis (hay fever) is the most common chronic disease in all industrialized nations. Therapy consists essentially in the use of anti-allergic and anti-inflammatory drugs, which mostly show a good and quick effect. With allergen-specific immunotherapy, there is also a causal possibility of tolerance induction. There is currentl...
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Societal Impact Statement Pollen relates to many aspects of human and environmental health, which protection and improvement are endorsed by the United Nations Sustainable Development Goals. By highlighting these connections in the frame of current challenges in monitoring and research, we discuss the need of more integrative and multidisciplinary...
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Climate change impacts on the structure and function of ecosystems will worsen public health issues like allergic diseases. Birch trees (Betula spp.) are important sources of aeroallergens in Central and Northern Europe. Birches are vulnerable to climate change as these trees are sensitive to increased temperatures and summer droughts. This study a...
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Pollen exposure weakens the immunity against certain seasonal respiratory viruses by diminishing the antiviral interferon response. Here we investigate whether the same applies to the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is sensitive to antiviral interferons, if infection waves coincide with high airborne pol...
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Climate change affects the reproductive life cycles of plants, including pollen production, which has consequences for allergic respiratory diseases. We examined climatic trends at eight locations in Bavaria, Southern Germany, with pollen time series of at least 10 years (up to 30 years in Munich). Climate change in Bavaria was characterized by a r...
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Background Pollen exposure has both acute and chronic detrimental effects on allergic asthma, but little is known about its wider effects on respiratory health. This is increasingly important knowledge as ambient pollen levels are changing with the changing global climate. Objective To assess associations of pollen exposure with lung function and...
Article
"An die Herausgeber Vor Kurzem (am 25. Juli 2019) hat die Europäische Union den Götterbaum (Ailanthus altissima [Mill.] Swingle, engl. Tree of Heaven) aus der Familie der Bittereschengewächse (Simaroubaceae) auf die „Liste invasiver gebietsfremder Arten von EU-weiter Bedeutung“ gesetzt. Damit steht dieser Baum unter Beobachtung und die Einfuhr, der...
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Letter to the editor - Open Access - https://link.springer.com/article/10.1007/s40629-020-00122-w
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Allergene Pollen sind natürliche, biologische luftgetragene Partikel und der Hauptauslöser allergischer Atemwegserkrankungen. Die Messung allergener Pollen ist Voraussetzung für die gesundheitliche Vorsorge und zeigt Veränderungen im Pollenspektrum an, wie sie zum Beispiel im Rahmen des Klimawandels zu erwarten sind. Das in Deutschland einzige bund...
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Airborne pollen is a recognized biological indicator and its monitoring has multiple uses such as providing a tool for allergy diagnosis and prevention. There is a knowledge gap related to the distribution of pollen traps needed to achieve representative biomonitoring in a region. The aim of this manuscript is to suggest a method for setting up a p...
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Betula pollen is frequently found in the atmosphere of central and northern Europe. Betula pollen are health relevant as they cause severe allergic reactions in the population. We developed models of thermal requirements to predict start, peak and end dates of the Betula main pollen season for Bavaria (Germany). Betula pollen data of one season fro...
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Large spatial differences in the distribution of three allergologically relevant pollen types for Central Europe—birch, grass, and mugwort—are revealed within a large metropolitan area—Berlin, Germany. The purpose of the study is an examination of the hypothesis that these different pollen exposure conditions can cause different degrees of pollen-i...
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Google Trends (GT) describes the variation of the relevant interest of internet searches toward medical conditions and related symptoms. Allergic rhinitis symptom levels result from the intensity of exposure to aeroallergens in combination with relevant medication use. We analyze data from Germany to examine the relationship between hay fever-relat...
Article
Allergic diseases are caused by a wide variety of relevant allergens, some of which are very common, while others affect rather few patients. For allergen immunotherapy, the Paul Ehrlich Institute (PEI) has taken this fact into account as the german regulation “Therapieallergene-Verordnung” (TAV) only applies to often occurring therapeutic allergen...
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Background: Early life factors are associated with allergic respiratory diseases, but the role of high grass pollen concentrations during pregnancy and shortly after birth is not known. Objective: To assess outdoor levels of grass pollen during the intrauterine period and at birth during peak pollen season on cord blood IgE in birth cohorts. Me...
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Background The use of allergen immunotherapy (AIT) for allergic rhinitis and its clinical efficacy in clinical trials depends on the effective determination of pollen allergens exposure time‐periods. We evaluate pollen data from Germany to examine the new definitions on pollen season and peak pollen period start and end as proposed by the European...
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Background Grasses release the most widespread aeroallergens with considerable sensitization rates, while different species produce several pollen concentration peaks throughout the season. This study analyzed the prevalence of grass species in three different European city areas and compared the flowering period of these species with daily pollen...
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The study investigated the seasonal courses and intradiurnal patterns of birch (Betula), grass (Poaceae), and mugwort (Artemisia) pollen at two sites in the city of Berlin in 2014 and 2015.
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In a recently published paper (Pfaar et al., 2016), a Task Force of the Immunotherapy and Aerobiology and Pollution Interest Groups of the EAACI suggested specific criteria for the definition of pollen exposure times for three types of pollen events: (a) Pollen Season (PS) start and end, (b) high pollen season (or Peak Pollen Period-PPP) start and...
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For nearly a decade, the majority of the world’s population has been living in cities, including a considerable percentage of people suffering from pollen allergy. The increasing concentration of people in cities results in larger populations being exposed to allergenic pollen at the same time. There is almost no information about spatial distribut...
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PurposeThe study investigated the seasonal courses and intradiurnal patterns of birch (Betula), grass (Poaceae), and mugwort (Artemisia) pollen at two sites in the city of Berlin in 2014 and 2015. Methods The “Motorway Site” was situated at a busy city motorway and the “City Center Site” on the roof of a large hospital. Sampling was undertaken with...
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Although beech (Fagus) pollen are often disregarded, they play an allergological role. This study focused on pollen season (PS) of European beech (Fagus sylvatica L.) and mean yearly temperatures (T) at two climatically different sites (lowlands vs. Alps) in Germany. Pollen sampling was conducted with 7-day recording volumetric spore traps between...
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Full-text available
In this study, the seasonally averaged intradiurnal patterns of four different pollen types (Fraxinus, Betula, Poaceae and Artemisia) and the role of traffic volume, air pollution and selected weather parameters were investigated. Measurements were carried out with a 7-day recording volumetric spore trap (Hirst type) near a congested city motorway...
Article
A six week pilot study campaign of parallel measurements of particulate matter (PM10) and pollen has been carried out during the pollination season of grass pollen in May/June 2011 in the city of Berlin. The measurements run as 24 h daily samplings at three monitoring sites, characterized as inner-city, suburban and traffic locations with different...
Article
Background: The study shows the findings concerning the distribution of pollen and particulate matter (particles < 10 μm; PM10) within an urban agglomeration, using the example of the city of Berlin as an example. Methods: Parallel measurements of pollen and PM10 in the air were carried out overduring six 6 weeks at three mon-itoring sites in the c...
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Background: In May / June 2011 the Foundation German Pollen Information Service (PID) and the Federal Environment Agency (UBA) conducted a study [1] concerning the distribution of pollen and particulate matter (PM10) in Berlin as an urban agglomeration. For catching pollen a Burkard trap was used. Parallel measurements took place near an urban moto...
Article
Background: The study shows the findings concerning the distribution of pollen and particulate matter (particles < 10 μm; PM10) within an urban agglomeration using the example of Berlin. Methods: Parallel measurements of pollen and PM10 in the air were carried out during six weeks at three monitoring sites in the city with different environment (in...
Article
Allergological significant pollen, such as hazel, alder, birch, grass, rye, mugwort and since 2006, ambrosia, has been measured in Germany by the Foundation German Pollen Information Service since 1983. During the last 11 years, small changes in the amount of pollen have occurred. Tree pollen has been appearing in rising concentration and grass pol...

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Project (1)
Project
1) Development of International cooperation and the use of valuable experiences of German researchers in the field of aerobiology for setting up equipment and developing methods for studying airborne materials. 2) Bioinformatics analysis of the long-term aerobiological trends of Tree of heaven in Berlin 3) Detection of Ailanthus major allergens sensitizing German patients using 1D-immunoblotting and compare the results with those obtained in Tehran. 4) This study will allow to define whether environmental factors, such as weather variables and climate are affecting the sensitisation profile of the population living exposed to this allergenic pollen.