Matthew J. Kmiecik

Matthew J. Kmiecik
23andMe · Research

Doctor of Philosophy
Postdoctoral research fellow studying the role of multisensory hypersensitivity in chronic pain.

About

34
Publications
3,932
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
48
Citations
Citations since 2016
26 Research Items
46 Citations
20162017201820192020202120220246810
20162017201820192020202120220246810
20162017201820192020202120220246810
20162017201820192020202120220246810
Introduction
Parkinson's Disease, volition, reasoning, thinking, semantic processing, executive dysfunction, traumatic brain injury, chronic visceral pain, sensory amplification. Methods and techniques: EEG (ERP and frequency), fMRI, behavioral analysis

Publications

Publications (34)
Article
Full-text available
Media violence exposure causes increased aggression and decreased prosocial behavior, suggesting that media violence desensitizes people to the emotional experience of others. Alterations in emotional face processing following exposure to media violence may result in desensitization to others' emotional states. This study used scalp electroencephal...
Article
Relational thinking involves comparing abstract relationships between mental representations that vary in complexity; however, this complexity is rarely made explicit during everyday comparisons. This study explored how people naturally navigate relational complexity and interference using a novel relational match-to-sample (RMTS) task with both mi...
Article
Increased sensory sensitivity across non-nociceptive modalities is a common symptom of chronic pain conditions and is associated with chronic pain development. Providing a better understanding of the brain-behavior relationships that underlie multimodal hypersensitivity (MMH) may clarify the role of MMH in the development of chronic pain. We studie...
Preprint
Full-text available
Multimodal hypersensitivity (MMH)---greater sensitivity across multiple sensory modalities (e.g., light, sound, temperature, pressure)---is a mechanism hypothesized to be responsible for the development of chronic pain and pelvic pain. However, previous studies of MMH are restricted given their reliance on biased self-report questionnaires, limited...
Poster
Full-text available
Better understanding of the mechanisms underlying perceived unpleasantness in response to a stimulus are critically needed to improve the treatment of sensory disorders such as migraine and chronic pain. We previously found that generally healthy, young adult women with preclinical evidence of pelvic hypersensitivity reported greater visual unpleas...
Poster
Full-text available
Background and Aims: Multimodal hypersensitivity (MMH) is a hallmark symptom associated with chronic pain conditions [3–5,8,10,12,14] and mechanisms responsible for MMH may be a key reason why individuals develop chronic pain [2,7] or a determinant of treatment response [6,9]. MMH is increased sensitivity across multiple sensory modalities (e.g., l...
Article
Prior studies of A:B::C:D verbal analogies have identified several factors that affect performance, including the semantic similarity between source and target domains (semantic distance), the semantic association between the C-term and incorrect answers (distracter salience), and the type of relations between word pairs. However, it is unclear how...
Poster
Full-text available
Introduction: Increased sensory sensitivity across non-nociceptive modalities is a common symptom of chronic pain conditions and has been shown in individuals with chronic pelvic pain (CPP); however, the neural mechanisms underlying this hypersensitivity are unknown. Understanding the brain-behavior relationships that explain multimodal hypersensit...
Preprint
Full-text available
Multisensory hypersensitivity (MSH), which refers to persistent discomfort across sensory modalities, is a risk factor for chronic pain. Developing a better understanding of the neural contributions of disparate sensory systems to MSH may clarify its role in the development of chronic pain. We recruited a cohort of women (n=147) enriched with parti...
Experiment Findings
Full-text available
This poster presents preliminary data from this study that was presented at the Cognitive Neuroscience Annual Meeting 2020 (virtual conference).
Poster
Full-text available
Mechanistic theories of the N400 event-related potential—a neural correlate indexing semantic processing in the brain—implicate the roles of prediction, priming, and bottom-up sensory integration in language comprehension; however, mechanisms explaining volitional aspects of semantic meaning construction are not fully understood. To explore this, p...
Poster
Full-text available
The locus coeruleus - norepinephrine system (LC-NE) – a primary dispenser of norepinephrine in the brain – modulates allocation of attention used in executive functioning and reasoning through connection tracts to the prefrontal cortex (PFC); however, the changes of norepinephrine related to decision-making when affected by transcranial direct curr...
Poster
Full-text available
Traumatic brain injuries (TBIs) occur when we receive a harmful blow to the head that results in disruptions to normal brain functioning. TBIs often cause cognitive deficits that include difficulties in concentration (e.g., mental fog), planning, and setting/achieving goals. These cognitive abilities are often classified more broadly as executive f...
Article
Full-text available
Background: Some individuals who sustain traumatic brain injuries (TBIs) continue to experience significant cognitive impairments chronically (months to years post injury). Many tests of executive function are insensitive to these executive function impairments, as such impairments may only appear during complex daily life conditions. Daily life o...
Poster
Full-text available
Analogical reasoning—our ability to abstract relational similarities between situations despite surface-level differences—varies between individuals; however, current analogy tasks are often not difficult enough to capture variability in performance across healthy and clinical populations. To address this challenge, we developed a scene analogy ass...
Poster
Full-text available
Performing relational comparisons is considered among the most intelligent cognitive capacities. Animal studies have demonstrated that chimpanzees and crows are capable of relational reasoning with second-order relationships (e.g., analogies); however, it has been hypothesized that only humans are capable of reasoning with third-order relationships...
Preprint
Background: Some individuals who sustain traumatic brain injuries (TBIs) continue to experience significant cognitive impairments chronically (months-to-years post-injury). Many tests of executive function are insensitive to these executive function impairments, as such impairments may only appear during complex daily life conditions. Daily life of...
Poster
Full-text available
Our ability to integrate increasingly complex relationships underlies human reasoning (Holyoak & Thagard, 1995), relies on the prefrontal cortex (e.g., Christoff et al., 2001; Waltz et al., 1999), and correlates with intelligence (Marshalek, Lohman, & Snow, 1983). Kroger, Holyoak, and Hummel (2004) demonstrated that comparing increasingly complex r...
Article
Full-text available
Clinical investigations of individuals with chronic stage traumatic brain injury (TBI) showing mild-to-moderate levels of residual impairment largely use standardized neuropsychological assessments to measure executive functioning. The Hayling Sentence Completion Test (HSCT) relies upon several executive functions but detects cognitive impairments...
Poster
Full-text available
Poster to be presented at the annual American Congress of Rehabilitation Medicine (ACRM) in Chicago, IL. Presents a partial least squares correlation analysis of the relationships between BOLD response and white matter microstructure in adults with chronic mild-moderate traumatic brain injury (TBI). Note: the currently published abstract in the Arc...
Presentation
Full-text available
In multivariate analyses, data are typically structured with observations (i.e., participants) on the rows and measurements (i.e., variables) on the columns. These data structure types are commonly analyzed with methods such as principal components analysis (PCA) or factor analyses (FA). However, PCA, FA, and related techniques are not always suita...
Poster
Full-text available
Analogical reasoning—the ability to understand and utilize relational similarities between entities despite surface-level differences—helps individuals solve problems and navigate through novel situations. This ability varies across healthy and clinical populations, yet current analogical reasoning tasks often fail to capture subtle performance var...
Conference Paper
Full-text available
Developmental, neuropsychological, and computational studies have suggested the importance of both relational knowledge and working memory in analogical reasoning. In this study, we investigated the extent to which individual differences in working memory (WM) and crystallized knowledge (Gc) predicted accuracies on a visual analogy verification tas...
Conference Paper
Full-text available
Computational accounts have traditionally focused on mapping between structured representations as fundamental to analogical processing. However, a recent connectionist model has been used to argue that structured representations may not be necessary to solve verbal analogies. Green and colleagues (2010) have shown that brain areas associated with...

Network

Cited By

Projects

Projects (6)
Project
Goal: to examine mechanisms of volition and how they may influence semantic access. Can our expectations influence how we process the meaning of objects (e.g., words) in our environment?
Project
Goals: 1) explore executive dysfunction in chronic-phase traumatic brain injury (TBI) using the Hayling Sentence Completion Test (Burgess & Shallice, 1996, 1997) and 2) improve how errors are scored by applying Latent Semantic Analysis (LSA; Landauer, Foltz, & Laham, 1998) and lexical estimates (e.g., word frequency) to characterize the quality of word generations.