Matthew Eng

Matthew Eng
University of Notre Dame | ND · Department of Biological Sciences

Doctor of Philosophy

About

15
Publications
1,728
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119
Citations
Introduction

Publications

Publications (15)
Article
Full-text available
The small cabbage white butterfly, Pieris rapae , is a major agricultural pest of cruciferous crops and has been introduced to every continent except South America and Antarctica as a result of human activities. In an effort to reconstruct the near-global invasion history of P. rapae , we developed a citizen science project, the “Pieris Project,” a...
Article
Surveillance for blood-fed female mosquitoes was performed between August 2015 and February 2016 at sites along the periphery of the Aripo Savannas Environmentally Reserve (ASSR) located in northeastern Trinidad, West Indies. We collected engorged female mosquitoes representing 13 species. DNA extractions from dissected abdomens were subjected to P...
Preprint
Full-text available
A major goal of invasion and climate change biology research is to understand the ecological and evolutionary responses of organisms to anthropogenic disturbance, especially over large spatial and temporal scales. One significant, and sometimes unattainable, challenge of these studies is garnering sufficient numbers of relevant specimens, especiall...
Article
Full-text available
Populations of Aedes aegypti naturally exhibit variable susceptibility to dengue viruses. This natural variation can be impacted by nutritional stress resulting from larval-stage crowding, indicating the influence of environment components on the adult mosquito immune response. In particular, larval crowding was previously shown to reduce the susce...
Data
Full gene lists delimited by module. (XLSX)
Data
Full hub gene lists delimited by module. (XLSX)
Data
Full gene ontology (GO) annotations delimited by module. (XLSX)
Data
qRT-PCR validation. Expression via relative quantitation to RPS17 endogenous control. (XLSX)
Article
Full-text available
The mosquito Aedes aegypti is the primary vector of human arboviral diseases caused by dengue, chikungunya and Zika viruses. Many studies have shown the potential roles of small RNA molecules such as microRNA, small interfering RNA and PIWI-interacting RNA in vector mosquitoes. The function of tRNA fragments (tRF), the newly discovered class of sma...
Data
Description of samples used in the study. (DOCX)
Data
List of 55 expressed tRFs and their mean read counts in males and females. (DOCX)
Data
Sex-biased changes in tRF abundance in Ae. aegypti. A) Principal component analysis of tRF abundance in males and females of 5 laboratory strains. The plot shows that males and females have different abundances of tRFs (the dotted line differentiates the two sexes). B) Plot of mutual information (MI) of variation of tRF abundance among males and fe...
Data
Tanglegram of tRF expression in males and females of Ae. aegypti. The variation of tRF expression in males across five strains is on left and that of females among the same strains are shown on right side of the plot. These expression patterns are shown as dendrograms of hierarchical clustering of tRF expression variation in males versus females. F...
Article
In addition to genetic history, environmental conditions during larval stages are critical to the development, success and phenotypic fate of the Aedes aegypti mosquito. In particular, previous studies have shown a strong genotype-by-environment component to adult mosquito body size in response to optimal vs stressed larval conditions. Here, we exp...
Article
The mosquito Aedes aegypti is the primary urban vector for dengue virus (DENV) worldwide. Insight into interactions occurring between host and pathogen is important in understanding what factors contribute to vector competence. However, many of the molecular mechanisms for vector competence remain unknown. Our previous global transcriptional analys...

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