Matthew Accatino

• BExcSci, MBBS, FRACP, MMed (MetabHlth)
• Endocrinologist at The Wesley Hospital

Progestin-associated meningioma is a rare complication of cyproterone acetate (CPA), an anti-androgen commonly prescribed in feminizing hormone therapy regimens for transgender and gender-diverse individuals. A dose-response association has been observed, particularly with longer-term exposure to doses ≥ 50 mg daily; however, the dose below which C...

Background The short Synacthen test (SST) is widely used to investigate adrenal insufficiency, but it can be time‐consuming, costly and labour‐intensive to perform and is not without risk of adverse events. Aim To review SST requesting patterns and practices across public hospitals in Queensland. Methods The electronic medical records of patients...

Background: Measurement of inpatient experience can allow for treatment tailored to patient preferences and needs. The patient experience of diabetes care has not been explored in Queensland hospitals. Aims: To investigate the experiences of patients with diabetes when hospitalised using the Queensland Inpatient Diabetes Survey (QuIDS). Methods:...

Azoles are among the most effective and widely used class of antifungals for prophylaxis, empirical and directed therapy against yeast and mould infections. Their use appears to be increasing worldwide. All triazoles cause hepatotoxicity, drug-drug interactions and QTc prolongation (except isavuconazole); however, there are growing concerns followi...

A 35‐year‐old man with known human immunodeficiency virus experienced chronic diarrhoea for 18 months. He presented to multiple hospitals with profuse secretory diarrhoea and life‐threatening electrolyte disturbances. Infectious and non‐infectious aetiologies were considered, with focussed history and investigations ultimately leading to a diagnosi...

Voriconazole‐associated periostitis (VAP) is an underrecognised and unpredictable side‐effect of long‐term voriconazole therapy. We report two cases of VAP occurring in the post‐transplant setting: a 68‐year‐old lung transplant recipient who required ongoing voriconazole therapy, in whom urinary alkalinisation was used to promote fluoride excretion...

Context The safety and efficacy of feminizing hormone therapy in aging transgender (trans) individuals is unclear. Current recommendations suggest transdermal estradiol beyond the age of 45 years, especially if cardiometabolic risk factors are present. Objective To evaluate feminizing hormone therapy regimens and cardiovascular risk factors in agi...

Background: Heterotopic ossification (HO) is a rare disease characterised by abnormal bone growth in non-osseous tissues, causing pain, immobility and impaired quality of life. Although still being elucidated, the underlying pathophysiology may relate to local macrophage-driven inflammation in response to trauma1. Case: A 35-year-old man involved i...