Matteo Cocuzza

Matteo Cocuzza
Politecnico di Torino | polito

MS, PhD

About

120
Publications
27,992
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1,808
Citations
Citations since 2016
71 Research Items
1404 Citations
2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300

Publications

Publications (120)
Chapter
Additive manufacturing (AM) includes a wide range of technologies that have been specialized to speed up the prototyping, especially in the field of mechanical engineering. In the last years, the use of polymer composites has opened novel opportunities in terms of functionalities to pave the way for a new generation of prototyping. Applications in...
Chapter
The chapters of this book describe the lively world which is moving around additive manufacturing (AM) and 3D printing with a deep focus on the polymer-based techniques and related applications. In the last chapter, final considerations on the future prospective are critically discussed to favor a better understanding of the expected next big steps...
Article
Electrolyte‐gated organic transistors (EGOTs) are emerging as an important tool in advanced biosensing applications. However, their widespread exploitation is still limited by their poor operational stability. In order to understand the causes of this unreliability, the proposed study focuses on the influence of electrical bias stress (EBS) on EGOT...
Article
In this work, we present a programmable dynamic cell culture stimulation platform designed to work in a CO2 incubator, compatible with a standard multi-well plate. An epithelial lung cell culture can be mechanically stimulated with a cyclic increase of the hydrostatic pressure inside the culture chamber in the range 1–12 kPa, trying to mimic the hu...
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In biosensing applications, the exploitation of organic transistors gated via a liquid electrolyte has increased in the last years thanks to their enormous advantages in terms of sensitivity, low cost and power consumption. However, a practical aspect limiting the use of these devices in real applications is the contamination of the organic materia...
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The development of traceable new methodologies to quantify elemental air pollutants in particulate matter (PM) supports modernization of methods used in air quality monitoring networks in Europe. In the framework of the EURAMET EMPIR AEROMET II project, the combination of cascade impactor aerosol sampling and total reflection X-ray fluorescence ele...
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Front Cover: Silver is recognized to reduce the proliferation of different bacteria classes. In the number 2100596 by Valentina Bertana and co-workers, a new process to prepare 3D-printed devices with antibacterial properties is reported. A photo-polymerizable blend is prepared by adding silver nitrate (AgNO3) in biocompatible PEGDA and photoinitia...
Article
Pancreatic ductal adenocarcinoma (PDAC) mainly develops in the head of the pancreas, within the acino-ductal unit composed of acinar and ductal cells surrounded by pancreatic stellate cells (PSCs). PSCs strongly influence the tumor microenvironment by triggering an intense stromal deposition, which plays a key role in tumor progression and limits d...
Article
In this paper, for the first time to the best of our knowledge, organic electrochemical transistors are employed to investigate the electrical response of human blood, plasma and alternative buffer solutions that inhibit red blood cell (RBC) aggregation. Our focus is on selecting a suitable electrolytic platform and the related operating conditions...
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The paper provides an overview of the several scientific and technical issues and challenges to be addressed for underground storage of carbon dioxide, hydrogen and mixtures of hydrogen and natural gas. The experience gained on underground energy systems and materials is complemented by new competences to adequately respond to the new needs raised...
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This work illustrates focalization performances of a silicon-based bulk acoustic wave device applied for the separation of specimens owing to micrometric dimensions. Samples are separated in the microfluidic channel by the presence of an acoustic field, which focalizes particles or cells according to their mechanical properties compared to the surr...
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A programmable dynamic cell culture chamber compatible with a standard multi-well plate was designed and characterized. The system is integrated with an array of OECT biosensors, in view of an in-situ monitoring of the dynamic cultures.
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In this work a new microfluidic platform is designed and validated to remove analyte contamination problem in EGOFETs biosensors.
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This work describes the fabrication of silver-patterned polymeric devices via light-based 3D printing methods from a tailored resin. An acrylate resin containing silver nitrate (AgNO3) as a silver precursor is employed to generate silver nanoparticles (AgNPs) through the in-situ reduction of the metallic salt. The silver-based resin is processed th...
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Miniaturized low-cost sensors for volatile organic compounds (VOCs) have the potentiality to become a fundamental tool for indoor and outdoor air quality monitoring, to significantly improve everyday life. Layered double hydroxides (LDHs) belong to the class of anionic clays and are largely employed for NOx detection, while few results are reported...
Article
Organic electronics has recently emerged as a promising candidate for the emulation of brain‐like functionalities, especially at the device level. Among the proposed technologies, memristive devices have gained an increasing attention due to their non‐volatile behavior which makes them suitable for the implementation of artificial neuronal networks...
Article
In the study of conductive conjugated polymers, electrical doping has long played an important role. A new polymeric gas sensor has been successfully fabricated by means of an ink-jet printer using a conductive aqueous formulation of poly(3,4-ethylenedioxythiophene) poly(styrene-sulfonate) (PEDOT:PSS). A simple yet robust treatment method for the i...
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In several biomedical applications, the detection of biomarkers demands high sensitivity, selectivity and easy-to-use devices. Organic electrochemical transistors (OECTs) represent a promising class of devices combining a minimal invasiveness and good signal transduction. However, OECTs lack of intrinsic selectivity that should be implemented by sp...
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Initially considered little more than a scientific curiosity, the family of 2D nanomaterials has become increasingly popular over the last decade [...]
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We report on the preparation and stereolithographic 3D printing of a resin based on the composite between a poly(ethylene glycol) diacrylate (PEGDA) host matrix and a poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (PEDOT:PSS) filler, and the related cumulative volatile organic compounds’ (VOCs) adsorbent properties. The control of all the...
Article
The effects of noise on any electronic system is a crucial aspect for the delineation of the proper functioning of circuits. Different and consolidated models have been proposed for classical electronic circuital elements but the effect of noise sourcing on memristive devices still lacks a wide and rich experimental description. Despite the larger...
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Organic Memristive Devices Organic memristive devices are crucial elements for the mimicking important synapse properties, such as memory and learning. For their larger uses in neuromorphic computation, it is necessary to improve their rate of the resistance switching and their stability. In article number 1900985, Silvia Battistoni, Victor Erokhin...
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Rapid Prototyping (RP) promises to induce a revolutionary impact on how the objects can be produced and used in industrial manufacturing as well as in everyday life. Over the time a standard technique as the 3D Stereolithography (SL) has become a fundamental technology for RP and Additive Manufacturing (AM), since it enables the fabrication of the...
Article
A two-step hot embossing process was used to transfer graphene and to fabricate Gr/Si Schottky photodiodes. As a direct graphene transfer technique through a hot embossing system, chemical vapor deposition Gr monolayer was transferred from copper foil to cyclic olefin copolymer foil without a poly(methylmethacrylate) sacrificial layer. Then, hot em...
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The present work describes a novel microfluidic free-flow electrophoresis device developed by applying three-dimensional (3D) printing technology to rapid prototype a low-cost chip for micro- and nanoparticle collection and analysis. Accurate reproducibility of the device design and the integration of the inlet and outlet ports with the proper tube...
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The isolation and analysis of circulating biomarkers, the main concern of liquid biopsy, could greatly benefit from microfluidics. Microfluidics has indeed the huge potentiality to bring liquid biopsy into the clinical practice. Here, two polydimethylsiloxane (PDMS)-based microdevices are presented as valid tools for capturing microRNAs biomarkers...
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Microbial fuel cells (MFCs) are bio-electrochemical devices able to directly transduce chemical energy, entrapped in an organic mass named fuel, into electrical energy through the metabolic activity of specific bacteria. During the last years, the employment of bio-electrochemical devices to study the wastewater derived from the food industry has a...
Article
Being promising elements for neuromorphic computation, memristive devices have been often described as crucial elements for the mimicking important synapse properties, such as memory and learning. Among them, Organic memristive devices (OMDs) can claim low cost fabrication processes and the easy tunability of their electrical properties. Up to now,...
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In-liquid biosensing is the new frontier of health and environment monitoring. A growing number of analytes and biomarkers of interest correlated to different diseases have been found, and the miniaturized devices belonging to the class of biosensors represent an accurate and cost-effective solution to obtaining their recognition. In this study, we...
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We propose a versatile method to evaluate the suitability of polymers for the fabrication of microfluidic devices for biomedical applications, based on the concept that the selection and the design of convenient materials should involve different properties depending on the final microfluidic application. Here polymerase chain reaction (PCR) is sel...
Conference Paper
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In-liquid biosensing is the new frontier of cells real time monitoring and biomarkers detection. In order to improve the stability and electrical properties of an Electrolyte Gated Organic Field Effect Transistor (EGOFET) biosensor, in this study we investigate the effect of the solvent and of the substrate modification on thin films of organic sem...
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The perspective of downscaling organic electrochemical transistors (OECTs) in the nanorange is approached by depositing poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) on electrodes with a nanogap designed and fabricated by electromigration induced break junction (EIBJ) technique. The electrical response of the fabricated devices...
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Graphene and 2D materials have been exploited in a growing number of applications and the quality of the deposited layer has been found to be a critical issue for the functionality of the developed devices. Particularly, Chemical Vapor Deposition (CVD) of high quality graphene should be preserved without defects also in the subsequent processes of...
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This work aims to show the feasibility of an innovative approach for the manufacturing of organic-based devices with a true three-dimensional and customizable structure that is made possible by plastic templates, fabricated by additive manufacturing methods, and coated by conducting organic thin films. Specifically, a three-dimensional prototype ba...
Conference Paper
Demulsification is the breaking of immiscible fluids into two phases, i.e. removing water in oil or oil in water. It is a fundamental step in oil processing. The main difficulty of demulsification is destabilizing emulsions to a satisfactory level for successive steps. Demulsification techniques can be grouped into three main categories: chemical,...
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In this work a new Single Layer Graphene (SLG) transfer technique exploiting a hot embossing process was carried out. Flexible electrolyte gated Graphene Field Effect Transistors (G-FET) were fabricated and tested electrically. A polymeric transparent foil suitable for optics and flexible electronics, Cyclic Olefin Copolymer (COC) was used as flexi...
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Blood-plasma separation is one of the main concerns for Point-of-Care devices seeking to retain cells of interest or analyze plasma biomarkers. The present work describes a novel passive device based on size-exclusion method. Starting from a particulate-trap-like filter, numerical simulations in ANSYS Fluent were performed in order to optimize the...
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Stereolithography 3D printing is today recognized as an effective rapid prototyping technique in the field of polymeric materials, which represents both the strengths and the weaknesses of this technique. The strengths relate to their easy handling and the low energy required for processing, which allow for the production of structures down to the...
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Organic electrochemical transistors (OECTs) represent a powerful and versatile type of organic-based device, widely used in biosensing and bioelectronics due to potential advantages in terms of cost, sensitivity, and system integration. The benchmark organic semiconductor they are based on is poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (...
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This work proposes a novel approach to investigate the behavior of single chamber microbial fuel cells (SCMFCs) based sensors by implementing fluid dynamic simulations to especially investigate the role of diffusion phenomena. When different flow rates are applied (i.e., 25 mL/h and 100 mL/h) the electrolyte flows differently into the cell, changin...
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The use of 3D printing for scientific and industrial applications is rapidly increasing and, simultaneously, is growing the interest toward printable smart materials. It is known that using a conductive filler, e.g. nanoparticles, metal powders or composite polymers, it is possible to produce a more electrically conductive printable material. The P...
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A new flexible polymeric gas sensor is developed by photocrosslinking poly(ethylene glycol) diacrylate resin (PEGDA) containing multi‐walled carbon nanotubes (MWCNTs) as conductive filler. The cured material shows a percolative threshold conductivity which changes when in contact with various gas analytes with different chemical and physical proper...
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Polydimethylsiloxane (PDMS) is a well-known biocompatible polymer employed for many applications in the biomedical field. In this study, the biocompatibility and versatility of PDMS was tested setting up a microdevice devoted to the purification and analysis of nucleic acids. The PDMS microdevice was demonstrated to successfully fulfill all require...
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In this paper, a three-layer dielectric structure is presented as innovative unit-cell element for Transmitarray (TA) Antennas with enhanced bandwidth. It consists of a central layer, with a varying size square hole, used to compensate the phase of the incident field and located between two other identical layers with linearly tapered square holes,...
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Herein the concomitant synthesis of a MoS2 and Cu7S4-decorated graphene aerogel is reported. The material is fully characterized and used as active material to coat carbon fiber electrodes for the fabrication of a fiber-shaped supercapacitor. The device provides excellent capacitance values warranting stable performance even at high bending angle c...
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We demonstrate the label-free and selective detection of Interleukin-6 (IL-6), a key cell-signaling molecule in biology and medicine, by integrating an OECT with an immuno-affinity regenerated cellulose membrane. The membrane is aimed at increasing the local concentration of IL-6 at the sensing electrode and, thereby, at enhancing the device respon...
Conference Paper
Organic Electrochemical Transistors (OECTs) represent a versatile tool successfully exploited in the field of Bioelectronics. In particular, OECTs have been used for the detection of a wide set of bioanalytes, often showing superior performance compared to that of commonly used sensors. In this study, we propose a flexible, disposable OECT, based o...
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This paper presents a critical review and the state of the art of graphene porous membranes, a brand-new technology and backdrop to discuss its potential application for efficient water desalination in low salinity water injection (LSWI). LSWI technology consists in injecting designed, adequately modified, filtered water to maximize oil production....
Conference Paper
Main parameters of the 1-5 diphenylcarbazide standard method for specrophotometrical detection of Cr(VI) metal ions in water were optimized for application on a miniaturized and portable device for continuous monitoring of water pollution. The aim was the reduction of involved volumes, manageable by a microfluidic device, the choice of suitable sol...
Article
Purpose This paper presents a study on a commercial conductive PLA filament and its potential application in a 3D printed smart cap embedding a resistive temperature sensor made of this material. The final aim of this study is to add a fundamental block to the electrical characterization of printed conductive polymers, which are promising to mimic...
Article
Two Photon Polymerization (2PP) is a powerful additive manufacturing technology already employed in the field of micro-/nano- engineering. The resolution achieved by 2PP 3D printing systems is in the range of hundreds of nanometers, but the printing volume is limited to few mm³ and printing times are not negligible. Therefore, it cannot be consider...
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Additive manufacturing techniques using three dimensional (3D) printing have been shown to be suitable for a wide range of applications. In this study, stereolithography (SLA) is applied to the field of microfluidic fabrication of lab-on-a-chip (LOC) devices. LOCs deal with different milli/microsized channels and chambers, which are the key feature...
Article
The Oil&Gas industry features peculiar characteristics and criticalities in terms of risk assessment and management, both for the environment and for human health. The offshore framework, due to its unique logistics, compactness and density of installations, is a further specificity for which various recommended practices and standards, constantly...
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In this paper, an innovative process flow developed to improve the thermal resistance of power ICs was presented. In this field, one of the major device failure mechanisms is related to the high temperatures reached during the working cycles due to the extremely critical electrical current densities. Therefore, heat transfer and dissipation are cru...
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It is not the first time in human history, nor will it be the last for that matter, that a collective problem calls for a collective response. Climate change fueled by greenhouse emissions affects humankind alike. Despite the disagreement among policymakers and scientists on the severity of the issue, the truth is that the problem remains. A broad...
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Purpose In this process the electrical contact is brought to the backside of a standard silicon wafer. The details of the entire process are disclosed, from the photolithography processes to the electrodepositing step, and a model for electrical contact was designed. Design/methodology/approach The localized Cu growth of high aspect ratio (AR) m...
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Cellular activity upon osmotic stress is related to the occurrence of several disease conditions. The real-time monitoring of the cell response to this kind of stress can give insight into the comprehension of mechanisms involved in cellular shrinkage. Currently the dynamics of the osmotic stress is studied using dedicated and tricky methodologies,...