Mathijs Mutsaers

Mathijs Mutsaers
Institute of Tropical Medicine | ITM · Department of Biomedical Sciences

Master of Biomedical Sciences in Tropical Diseases
Scientific Assistant in Malariology and responsible for Malaria molecular surveillance using NGS.

About

7
Publications
5,534
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43
Citations
Introduction
Mathijs Mutsaers studied at Antwerp University, where he completed a Master Biomedical Sciences in Tropical Infectious Diseases. Overseas in Rio de Janeiro (Fiocruz), he did research on new arbovirus diagnostics and vector control. Lateron, he did a Ma-na-Ma in International Relations in which he gained extra understanding of economics, development and international policies. Now he works for the ITM on the topic that fascinates him the most: mosquito-borne diseases, focus on Malaria.
Education
September 2018 - June 2020
University of Antwerp
Field of study
  • Political Sciences
November 2017 - May 2018
Oswaldo Cruz Foundation
Field of study
  • Vector ecology - ZIKA & Wolbachia
September 2016 - June 2018
University of Antwerp
Field of study
  • Tropical Infectious Diseases (minor: Research)

Publications

Publications (7)
Article
Full-text available
Introduction Vietnam’s goal to eliminate malaria by 2030 is challenged by the further spread of drug-resistant Plasmodium falciparum malaria to key antimalarials, particularly dihydroartemisinin-piperaquine (DHA-PPQ). Methods The custom targeted NGS amplicon sequencing assay, AmpliSeq Pf Vietnam v2, targeting drug resistance, population genetic- a...
Article
Full-text available
Background Plasmodium vivax is the most predominant malaria species in Latin America, constituting 71.5% of malaria cases in 2021. With several countries aiming for malaria elimination, it is crucial to prioritize effectiveness of national control programs by optimizing the utilization of available resources and strategically implementing necessary...
Article
Full-text available
Background Failure of artemisinin-based combination therapy (ACT) is increasingly reported in patients with Plasmodium falciparum malaria in sub-Saharan Africa. We aimed to describe the clinical and genomic characteristics of recent cases of P. falciparum malaria failing artemether-lumefantrine in Belgium. Methods Travel-related cases of malaria c...
Preprint
Full-text available
Background Plasmodium vivax is the most predominant malaria species in Latin America, constituting 71.5% of malaria cases in 2021. With several countries aiming for malaria elimination, it is crucial to prioritize effectiveness of national control programs by optimizing the utilization of available resources and strategically implementing necessary...
Article
Full-text available
Malaria molecular surveillance has great potential to support national malaria control programs (NMCPs), informing policy for its control and elimination. Here, we present a new three-day workflow for targeted resequencing of markers in 13 resistance-associated genes, histidine rich protein 2 and 3 (hrp2&3), a country (Peru)-specific 28 SNP-barcode...
Article
Full-text available
Deployment of Wolbachia to mitigate dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) transmission is ongoing in 12 countries. One way to assess the efficacy of Wolbachia releases is to determine invasion rates within the wild population of Aedes aegypti following their release. Herein we evaluated the accuracy, sensitivity and specificity of the...
Thesis
Full-text available
Research on the alternative method Near Infrared Secptroscopy (NIRS) in surveillance of Aedes agypti vector control with Wolbachia. Molecular assays like PCR and ELISA are costly, destructive and time consuming. In contrast, near infrared spectroscopy indirectly detects Wolbachia wMel infection (an endosymbiont that supresses arboviruses) in fresh...

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