Matěj Malík

Matěj Malík
Czech University of Life Sciences Prague | CULS · Department of Agroenvironmental Chemistry and Plant Nutrition

Ph.D.

About

20
Publications
6,914
Reads
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166
Citations
Education
September 2018 - March 2023
Czech University of Life Sciences Prague
Field of study
  • Plant Science
September 2016 - June 2018
University of Chemistry and Technology, Prague
Field of study
  • Chemistry of Natural Compounds
September 2013 - June 2016

Publications

Publications (20)
Article
Full-text available
The use of cannabis for medicinal purposes dates back well before the era of modern medicine, but in recent years research into the use of medical cannabis in the medical and pharmaceutical sciences has grown significantly. In European countries, most cannabis plants have been and still are grown for industrial purposes. For this reason, hemp culti...
Article
Full-text available
There is growing evidence to support the involvement of nutrients and biostimulants in plant secondary metabolism. Therefore, this study evaluated the potential of amino acid-based supplements that can influence different hydroponic nutrient cycles (systems) to enhance the cannabinoid and terpene profiles of medical cannabis plants. The results dem...
Article
Full-text available
Nootropics, also known as “smart drugs” are a diverse group of medicinal substances whose action improves human thinking, learning, and memory, especially in cases where these functions are impaired. This review provides an up-to-date overview of the potential effectiveness and importance of nootropics. Based on their nature and their effects, this...
Article
Introduction: The use of Cannabis sativa L. in health care requires stringent care for the optimal production of the bioactive compounds. However, plant phenotypes and the content of secondary metabolites, such as phytocannabinoids, are strongly influenced by external factors, such as nutrient availability. It has been shown that phytocannabinoids...
Article
Rising temperatures, higher water consumption for irrigation, and the discharge of agricultural wastewater may soon adversely affect water resources across the entire planet and its people. Agriculture consumes large amounts of water, and there is a pressing need to explore possibilities for recirculation and reuse of nutrient solutions to reduce t...
Article
Full-text available
The utilization of natural resources in traditional medicine has long served as a wellspring of inspiration for modern biomedical research. Campsis radicans (L.) Bureau, commonly known as trumpet creeper, occupies a significant place in traditional healing practices across various cultures. This review study, conducted in the early part of 2024, ai...
Article
Full-text available
Agaritine, a naturally occurring amino acid and phenylhydrazine derivative found in mushrooms of the genus Agaricus, has gained attention due to its potential impact on human health. The presence of the hydrazine moiety in the structure of agaritine plays a crucial role in its toxicological properties. It has raised concerns due to its high reactiv...
Article
Full-text available
Antibiotic resistance in staphylococcal strains and its impact on public health and agriculture are global problems. The development of new anti-staphylococcal agents is an effective strategy for addressing the increasing incidence of bacterial resistance. In this study, ethanolic extracts of Cannabis sativa L. made from plant parts harvested durin...
Article
Full-text available
Growing evidence underscores the role of nutrients and fertigation systems in soilless production, influencing medicinal cannabis biomass and secondary metabolite content. This study delves into the impact of enhanced nutrient regimes on the ‘ionome’ and its ramifications for biomass and cannabinoid production in medicinal cannabis, comparing two d...
Article
Full-text available
Bracken fern (Pteridium aquilinum (L.) Kuhn) is ubiquitous and acts as a cosmopolitan weed in pastures and similar environments. Despite its historical uses, it presents risks due to toxicity. This study, conducted in the second half of 2023, aimed to assess the environmental and health hazards of P. aquilinum, primarily focusing on its carcinogeni...
Article
Full-text available
Plant-based nootropics are a diverse group of natural drugs that can improve cognitive abilities through various physiological mechanisms, especially in cases where these functions are weakened or impaired. In many cases, the nootropics enhance erythrocyte plasticity and inhibit aggregation, which improves the blood's rheological properties and inc...
Article
Full-text available
Locikové opium je zaschlá mléčná šťáva, která vytéká při naříznutí Lociky jedovaté (Lactuca virosa L.). Šťáva má hořkou chuť a po vysušení ztvrdne a zhnědne. Ve středověku byla známá jako lactucarium a používána jako levná náhraž-ka opia známá pod názvem locikové opium. 1 Lactucarium bylo využíváno jako lék proti boles-ti, laxativum a sedativum. 2...
Conference Paper
This experiment compares the effect of recirculation and drain-to-waste nutritional hydroponic cycles on the content and yield of tetrahydrocannabinolic acid (THCA). In the recirculation cycle, higher concentrations, and total yields of THCA were achieved with lower nutrient consumption but with a longer cultivation time. Conversely, the drain-to-w...
Conference Paper
This article examines the effect of additional nutrition on the utilization of elements from nutrient solutions into cannabis flowers and its effect on cannabinoid profile of medical cannabis plants. The addition of amino acids mixture increased the flowers accumulation of nitrogen and sulphur, but on the contrary reduced the flowers utilization of...
Article
Full-text available
In a two-year vegetation field experiment, the fertilizing effects of by-products from the agricultural biogas plant—a solid phase of digestate (SPD) and a liquid phase of digestate (LPD)—were studied and compared with mineral fertilization (NPK) on the biomass yield, content and nutrient uptake by Cannabis sativa L. plants. Furthermore, the agroch...
Article
The importance of natural raw materials has grown recently because of their ready availability, renewable nature, biocompatibility and controllable degradability. One such group of plant-derived substances includes the triterpenoid acids, terpenic compounds consisting of six isoprene units, a carboxyl group and other functional groups producing var...
Conference Paper
Due to the insufficient amount of scientific literature in the field of medical cannabis nutrition, it is necessary to fill these gaps in knowledge, not only due to the growing demand for this raw material but also associated demands on its quality. This experiment shows that by the application of an additive with an increased content of potassium...
Conference Paper
The use of cannabis for medicinal purposes dates back well before the era of modern medicine, but in recent years research into the use of medicinal cannabis in the medical and pharmaceutical sciences has grown significantly. The number of active substances under investigation is increasing and their effect on a wide range of diseases is being stud...
Article
Cancer has been a global disease of great importance, and a need for novel cytotoxic drugs has still been eminent. A series of spermine amides of several selected triterpene acids (betulonic, heterobetulonic, oleanolic, ursolic and platanic acid) has been synthesized to search for new cytotoxic and antimicrobial agents. The compounds have also been...

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