Massimo Vignoli

Massimo Vignoli
Faculty of Veterinary Medicine · University of Teramo

Prof. Dr. Med. Vet., Ph.D., S.R.V., Dipl. E.C.V.D.I.

About

131
Publications
19,348
Reads
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1,160
Citations
Additional affiliations
December 2015 - present
Faculty of Veterinary Medicine, University of Teramo, Italy
Position
  • Professor (Associate)
Education
September 2008 - October 2010
Ghent University
Field of study
October 2001 - September 2008
Zuerich/Turin
Field of study
January 1995 - October 1997
Torino
Field of study

Publications

Publications (131)
Article
Full-text available
(1) Background: The double pelvic osteotomy (DPO) is a prophylactic surgical procedure associated with 0.4% incidence of sciatic nerve injury. The piezoelectric cutting tool is a surgical device able to involve only mineralized tissue avoiding neurovascular tissue and other soft tissue. This study aimed to evaluate the sciatic nerve injury observed...
Article
Full-text available
To date, the only method of sampling lung tissue with a high diagnostic yield is represented by surgical lung biopsies (SLB), which are highly invasive and have a high risk/benefit ratio. In humans, transbronchial lung cryobiopsies (TBLC) have recently been introduced, which are described to be less invasive and able to significantly increase diagn...
Article
Full-text available
Magnetic resonance relaxometry is a quantitative technique that estimates T1/T2 tissue relaxation times. This has been proven to increase MRI diagnostic accuracy of brain disorders in human medicine. However, literature in the veterinary field is scarce. In this work, a T1 and T2-based relaxometry approach has been developed. The aim is to investig...
Article
Stage III laryngeal collapse is defined as the collapse of the corniculate processes of the arytenoid cartilages and the destructuration of the dorsal portion of the rima glottidis. The primary cause is chronic upper airway obstruction, and the condition is often present in brachycephalic dogs. The treatment is still controversial; the patients are...
Article
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An 18-year-old Salernitano stallion developed a progressive enlargement of the left testicle over eight months. An ultrasound evaluation was performed, along with a hormonal profile. A histopathological evaluation of the testis was performed after unilateral orchiectomy. On B-mode ultrasound examination, testicular parenchyma was characterized by t...
Preprint
Full-text available
High field MRI represents an advanced technique both for diagnostic and research purposes on animal models such as the Beagle dog. The increasing interest in non-invasive neuroscience, aging, and neuropathological research led to a need of reference values (in terms of volumetric assessment) for the typical brain structures involved and, nowadays,...
Article
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Minimally invasive surgery is increasingly being used in veterinary medicine. Laparoscopic procedures have several advantages compared with open surgery. These include the magnification of the field of surgery, reduced post-surgical pain and associated stress, reduced post-operative infection rates, and decreased hospitalization time. The establish...
Article
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Canine hepatozoonosis caused by Hepatozoon canis is an emerging disease in Europe. Clinical pictures vary from subclinical to life-threatening and non-specific clinical signs are predominantly reported. A 2-month-old female puppy originating from Southern Italy was adopted and moved to Northern Italy. Then, the dog was brought to a local veterinary...
Article
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A pedicled jejunal graft was successfully used to treat a colorectal anastomotic dehiscence, which eliminated the tension on the anastomotic site.
Article
The presence of a significant quantity of gas in the gastrointestinal tract may hinder a proper ultrasonographic examination of the abdominal organs. The objective of this study was to investigate the influence of simethicone and fasting on the quality of ultrasonographic examinations of the gastrointestinal tract and the small organs in the abdomi...
Article
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We herein report the magnetic resonance imaging (MRI) findings in a brain meningioma in a pet rat (Rattus norvegicus domestica). A 1.5-year-old pet rat was referred for depression, ataxia, tremors and bilateral nystagmus; a brain MRI was elected suspecting an intracranial neoplasia. The study was performed with a 0.25 T scanner. The MRI revealed a...
Article
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The mitochondrial DNA (mtDNA) D-loop of endangered and critically endangered breeds has been studied to identify maternal lineages, characterize genetic inheritance, reconstruct phylogenetic relations among breeds, and develop biodiversity conservation and breeding programs. The aim of the study was to determine the variability remaining and the ph...
Article
Mammary gland neoplasms are predominant in dogs. However, sentinel lymph node (SLN) status assessment criteria have not been established for these cases. In this retrospective, secondary analysis, diagnostic case control study, CT images of 65 superficial inguinal SLNs were obtained before and 1, 3, 5, and 10 min after intravenous administration of...
Article
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Background Capsulitis leads to the release of inflammatory mediators in the joint, causing capsular fibrosis and osteoarthritis (OA). Strain elastosonography (SE) measures the elasticity of tissue by evaluating its strain in operator-dependent deformation. The aims of the study were to assess the feasibility, repeatability, and reproducibility of S...
Article
Full-text available
Mammary gland tumors are the most common canine neoplasms. They account for 25–50% of all tumors diagnosed in bitches. Metastases and recurrences develop in about 35–70% of bitches following excision. The presence of regional lymph node metastases is a relevant factor affecting prognosis and treatment in cases of mammary gland tumors. The sentinel...
Article
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Diagnosis of thoracic lesions on the basis of history and physical examination is often challenging. Diagnostic imaging is therefore of paramount importance in this field. Radiology has traditionally been considered the diagnostic procedure of choice for these diseases. Nevertheless, it is often not possible to differentiate inflammatory/infectious...
Article
Full-text available
The morphological characteristics of the largest lymphatic vessels and lymph nodes of the body have been described through ultrasonography, although food and gas in the gastrointestinal tract can often have negative effects on the response of small abdominal structures. The aim of the study was to describe the size of normal abdominal lymph nodes (...
Article
Full-text available
Canine gastric disorders are common in veterinary clinical practice and among these neoplasms require rapid identification and characterization. Standard ultrasound (US) is the imaging modality of choice for gastric wall assessment. The aim of this prospective study is to describe the specific B-mode and contrast enhanced US (CEUS) features of norm...
Article
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The objectives of this retrospective study of 240 guinea pigs (148 females and 92 males) were to determine the prevalence of different vertebral formulae and the type and anatomical localization of congenital vertebral anomalies (CVA). Radiographs of the cervical (C), thoracic (Th), lumbar (L), sacral (S), and caudal (Cd) part of the vertebral colu...
Article
Full-text available
Prostatic neoplasia (PN) occurs in 5–7% of dogs with prostatic disease, with castrated dogs having the same or higher prevalence when compared to intact dogs. Considering the promising results achieved by performing contrast-enhanced ultrasound (CEUS) in intact dogs to detect PN, the present study aimed to acquire data on the prostatic perfusion pa...
Preprint
Full-text available
Background: Capsulitis leads to the release of inflammatory mediators into the joint causing capsular fibrosis and osteoarthrosis (OA). Strain elastosonography (SE) measures the elasticity of tissue evaluating its strain to an operator-dependent deformation. Aims of the study were to assess the feasibility of SE for evaluating the distal attachment...
Preprint
Full-text available
Magnetic Resonance Relaxometry is a quantitative MRI-based technique able to estimate tissue relaxation times T1 and T2. This approach allows increasing the MRI diagnostic accuracy mostly in case of brain neoplasia or neurodegenerative disorders in human medicine. However, few reports are available on the application of this technique in the clinic...
Article
Full-text available
The liver has a unique vascular supply, and triple-phase contrast-enhanced computed tomography examinations are being performed in order to characterize liver lesions. This study aimed to look for any associations between the attenuation values of liver lesions and their histological classification. The inclusion criteria for this retrospective stu...
Article
Shear wave elastography (SWE) is a feasible and newly developed ultrasonographic technique which is able to assess elasticity of tissues. The aim of this work was to assess the feasibility of SWE on the normal canine common calcaneal tendon (CCT) evaluating the intra-operator repeatability and reproducibility of single measurements and stiffness of...
Article
KEY POINTS - Whole-body computed tomography (WBCT) is a diagnostic tool that rapidly provides detailed information of the body. - This technique is applied in veterinary medicine to fully characterize lesions in dogs and cats with polytrauma. - In oncology, WBCT is of paramount importance to assess for the presence of metastasis, in particular in p...
Article
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Alimentary lymphoma (AL) is the most common malignancy of the feline gastrointestinal tract and may cause variable mild to severe alteration of the gastric wall on ultrasonography (US) that can be very similar to those caused by inflammation (INF). The aim of this prospective study is to establish the value of B-mode and contrast-enhanced US (CEUS)...
Article
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This study aimed to evaluate the clinical and radio graphical outcome of cats following TPLO surgery for cranial cruciate ligament deficiency. Each cat underwent orthopedic assessment, pre-operative radio graphical evaluation, surgical procedure, postoperative management and clinical re-examination 1, 2, and 12 months following surgery. Age, body w...
Article
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Background: There is a lack of information regarding the CT appearance of sternal lymph nodes in dogs. This retrospective anatomic study was aimed to describe the general appearance of sternal lymph nodes in healthy dogs. Results: Twenty-seven dogs with no abnormality in blood work, urinalysis and CT images were included in the study. Dogs were...
Article
Background There is a lack of information regarding the CT appearance of sternal lymph nodes in dogs. This retrospective anatomic study was aimed to describe the general appearance of sternal lymph nodes in healthy dogs. Results Twenty-seven dogs with no abnormality in blood work, urinalysis and CT images were included in the study. Dogs were divi...
Article
Full-text available
A urinoma is a collection of urine surrounded by a fibrotic wall and, in the veterinary medicine, this condition is rarely reported. The aim of this study is to describe the clinical and therapeutic features of two cats with post traumatic urinomas, with particular attention paid to the imaging findings. In both patients, well-defined anechoic flui...
Article
Full-text available
Introduction: Persistent Müllerian duct syndrome (PMDS), or uterus masculinus, is a rare autosomal recessive form of male pseudohermaphroditism due to the failure of paracrine anti-Müllerian hormone (AMH) secretion by Sertoli cells or failure of the Müllerian ducts to respond to AMH secretion. The malignant degeneration of persistent Müllerian remn...
Article
This study evaluated the accuracy and diagnostic quality of histological samples obtained with the Spirotome device on biopsies from dogs affected by canine nasal tumors. Eleven dogs were included in this study. The mean age was 10 years. All biopsies were successfully performed within 15 minutes. All dogs showed nasal bleeding after the biopsies,...
Article
Full-text available
Gastrointestinal tract tumours in dogs and cats are characterized by non-specific clinical presentation and laboratory abnormalities, but require fast identification, characterization and staging. Imaging techniques play a key role in the diagnostic process of these diseases in routine veterinary practice. Survey and contrast radiography may indica...
Preprint
Full-text available
Background The morphological characteristics of the largest lymphatic vessels and lymph nodes of the body have been described through ultrasonography, although food and gas in the gastrointestinal tract can often have negative effects on the response of small abdominal structures. The aim of the study was to describe the size of normal abdominal ly...
Article
Incomplete ossification of the humeral condyle is a cause of forelimb lameness in dogs. Affected dogs are predisposed to humeral condylar fractures. Incomplete ossification of the humeral condyle has been reported in breeds such as Spaniel, Rottweiler, Labrador and Pug. Diagnosis is made by a radiographic or computed tomographic study of the elbow,...
Article
Full-text available
This report is aimed at describing a pericardial patch for unresectable cardiac tumors as a palliative technique to prevent pleural effusion. Each dog underwent the same diagnostic protocol including a cardiological assessment, hematology and biochemistry profile, urinary test, abdominal and heart ultrasonography and chest radiographs. Computed tom...
Article
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The aim of this study was to evaluate, during the first 4 wk of life, the involution of umbilical structures in clinically healthy calves and in calves affected by umbilical disorders, in both B-mode and color Doppler ultrasonography. The present study was carried out on 63 Holstein Friesian calves, divided into 3 different groups: group H (clinica...
Poster
Full-text available
The aim of the study was to compare SLN between dogs with and without pathologies. Dogs with pathology inside the draining area demonstrated bigger DV and LL SLN dimensions, but not CrCd. Pre-contrast SLN density could differentiate normal and pathologic SLN, however, the postcontrast density is of no value. Short-to-long axis ratio seems to be un...
Preprint
Background: There is a lack of information regarding the CT appearance of sternal lymph nodes in dogs. This retrospective anatomic study was aimed to describe the general appearance of SLN in healthy dogs. Results: Twenty-eight dogs with no abnormality in blood work, urinalysis and CT images were included in the study. Animals were divided into thr...
Article
Full-text available
Background Aelurostrongylus abstrusus is the most important nematode affecting the respiratory tract of cats in terms of prevalence and clinical relevance. The aim of this randomised controlled field study was to confirm the efficacy of the spot-on containing emodepside/praziquantel (Profender, Bayer Animal Health) in the treatment of aelurostrongy...
Article
Full-text available
Radiography is routinely used for pelvimetry, but it is not easily accessible for farm animals, while ultrasonographic pelvimetry could be used due to the better accessibility and lack of radiation hazard. Radiographic and ultrasonographic pelvimetry in goats were compared, and three diameters of the pelvis were measured; the narrowest transverse p...
Article
Full-text available
To describe transscleral ultrasonography as a novel alternative approach for visualising the optic nerve sheath and measuring its diameter and to analyse the linear regressions of the optic nerve sheath diameter value with the weights and morphometric measurements of the globe in dogs. Forty healthy dogs admitted for routine sterilisation were exam...
Preprint
Full-text available
Background: There is a lack of information regarding the CT appearance of sternal lymph nodes in dogs. This retrospective anatomic study was aimed to describe the general appearance of sternal lymph nodes in healthy dogs. Results: Twenty-seven dogs with no abnormality in blood work, urinalysis and CT images were included in the study. Dogs were div...
Article
Magnetic Resonance (MR) is a non-invasive modality of choice for the evaluation of brain morphology, with superior performance as compared to other techniques. However, MR images are typically assessed qualitatively, thus relying on the experience of the involved radiologist. This may lead to errors of interpretation in the presence of subtle alter...
Article
A large, ill-defined, firm, multinodular mass involving the pancreas was confirmed on postmortem examination of a 5-y-old, male Rottweiler that died following acute respiratory distress syndrome, after a period of anorexia and lethargy. Histologically, the mass consisted of plump spindle cells admixed with a variable number of macrophages, lymphocy...
Article
Full-text available
The goal of this study was to report the first case of antral stenosis in a cat. We have described a clinical case of a 9 months old domestic shorthaired cat referred for persistent and refractory vomiting, anorexia and loss of weight. Ultrasound (US) examination detected a mild gastric distension, mild wall thickening (5mm), severe serosal irregul...
Article
Full-text available
Background Skeletal muscle metastases (SMMs) have been described sporadically in canine oncology. Hypothesis/Objectives To determine the prevalence, localization, and clinical signs of SMMs associated with hemangiosarcoma (HSA) in a population of dogs presented for whole body computed tomography (CT). Animals Dogs with a histologically confirmed...
Article
Objectives: This study has compared clinical and imaging features in 52 cats naturally infected by respiratory nematodes Aelurostrongylus abstrusus, Troglostrongylus brevior and Capillaria aerophila, and in both monospecific and mixed infections. Methods: Medical records of cats with a lungworm disease were retrospectively reviewed. Cats with cl...
Article
The aim of this retrospective study of 330 rabbits (164 males, 166 females) was to determine different vertebral formulas and prevalence of congenital vertebral anomalies in rabbits from radiographs of the cervical (C), thoracic (Th), lumbar (L) and sacral (S) segments of the vertebral column. The number of vertebrae in each segment of vertebral co...
Article
Full-text available
A 12 year old male Fox Terrier (case 1) and a one year old female Poodle (case 2) were presented with a history of dysorexia and vomiting, and case 2 also with distress associated with eating. Both dogs were diagnosed with acute pancreatitis based on clinical signs, blood analysis and ultrasonography which revealed the presence of a vegetable forei...
Article
Full-text available
This prospective study was aimed at testing a modified method for the measurement of the tibial plateau angle on radiographs of the stifle joint and the proximal part of the tibia. Forty-four stifle joints of 32 client-owned dogs were included in this study. Dogs were presented for hindlimb lameness and suspected cranial cruciate ligament rupture....
Article
The goal of this study was to describe the ultrasonographic and computed tomographic appearance of a penile foreign body in a dog for the first time. We describe an unusual penile localisation of a grass seed awn in an 11-year-old mixed-breed dog referred for a computed tomography study after a severe haemorrhage from the penis. A fistulous tract w...
Article
This report describes an unusual computed tomographic (CT) hepatic pattern, characterized by negative attenuation values (from –19.59 to –28.85 Hounsfield Units, HU) in a canine patient with severe Cushing's syndrome. Attenuation values of the splenic parenchyma (63.26 HU) and abdominal fat (–118.34 HU) were within normal limits. The negative hepat...
Article
Full-text available
A better understanding of the CT features of different forms of canine and feline adipose tumors would be valuable for improving patient management and treatment. The purpose of this retrospective, cross-sectional study was to describe and compare the CT features of pathologically confirmed lipomas, infiltrative lipomas, and liposarcomas in a sampl...
Article
Objectives The aim of this study was to retrospectively describe clinical, radiographic and therapeutic features of feline lungworm infection. Methods Medical records of cats with lungworm diagnosis, thoracic radiography and without concurrent diseases between 2013 and 2015 were reviewed. Collection of data included physical examination, haematolo...
Article
A prospective study to create radiographic classification of caudal vertebral anomalies in dogs was performed and the prevalence of the disorders estimated. Radiographic examination of the caudal vertebrae was performed in 595 client-owned dogs undergoing routine radiological examination of the hip joints. Anomalies of the caudal vertebrae were div...
Article
The aim of this study was to evaluate a large-core manual biopsy device (Spirotome®, Medinvents, 3500 Hasselt, Belgium) for liver sampling and histologic diagnosis in green iguanas ( Iguana iguana ). The study included eight green iguanas, and two ultrasound-guided biopsies were collected for each lizard, for 16 biopsies in total. The procedure was...
Article
Full-text available
Context: An increase in enzyme lactate dehydrogenase (LDH) in serum is a negative prognostic factor for survival in cats affected by lymphoma. Measuring LDH at the time of diagnosis has been studied for differentiating neoplastic disease from non-neoplastic disease in dogs. Inflammatory bowel disease (IBD) and alimentary lymphoma are common diseas...
Data
List of the SPSS (statistical package version 23) commands used for producing all the results reported in the paper. (DOCX)