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Massimiliano Carassiti

Massimiliano Carassiti
University Campus Bio-Medico of Roma School of Medicine · Anesthesia, ICU, Pain Management

About

119
Publications
10,743
Reads
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1,407
Citations
Citations since 2016
49 Research Items
603 Citations
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2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120
2016201720182019202020212022020406080100120

Publications

Publications (119)
Article
Full-text available
Study design Systematic Review. Objectives The aim of this systematic review is to evaluate the efficacy of non-invasive procedures in relieving chronic pain due to Failed Back Surgery Syndrome (FBSS). Methods Since patients who suffered from FBBS are often non-responders to analgesics, we compared Visual Analogical Scale for low back and leg pai...
Article
Full-text available
Fiber Bragg grating sensors (FBGs) are considered a valid sensing solution for a variety of medical applications. The last decade witnessed the exploitation of these sensors in applications ranging from minimally invasive surgery to biomechanics and monitoring physiological parameters. Recently, preliminary studies investigated the potential impact...
Article
Full-text available
Shoulder surgery has radically evolved within the last 70 years, from a marginal orthopedic sub-specialty to an area of great research and advancement; consequently, anesthetic techniques have undergone important development. In fact, a wide variety of anesthetic strategies have emerged, to provide anesthesia and post-operative analgesia: general a...
Article
Full-text available
Low back pain represents a significant socioeconomic burden. Several nonsurgical medical treatments have been proposed for the treatment of this disabling condition. Epidural steroid injections (ESIs) are commonly used to treat lumbosacral radicular pain and to avoid surgery. Even though it is still not clear which type of conservative intervention...
Article
The presence of a large blood vessel in the proximity of tumor masses during microwave ablation (MWA) can compromise the procedure success. Blood vessels cause convective heat dissipation (i.e., heat sink effect, HSE) in the tissue surrounding the vessel. In this scenario, cytotoxic temperatures may not be achieved within the target area, resulting...
Article
Full-text available
Bone metastases and osteoid osteoma (OO) have a high incidence in patients facing primary lesions in many organs. Radiotherapy has long been the standard choice for these patients, performed as stand-alone or in conjunction with surgery. However, the needs of these patients have never been fully met, especially in the ones with low life expectancy,...
Article
Full-text available
Epidural analgesia represents a clinical common practice aiming at pain mitigation. This loco-regional technique is widely used in several applications such as labor, surgery and lower back pain. It involves the injections of anesthetics or analgesics into the epidural space (ES). The ES detection is still demanding and is usually performed by the...
Article
Full-text available
(1) Background: The aim of this retrospective study is to assess safety and efficacy of lung radiofrequency (RFA) and microwave ablation (MWA) using an augmented reality computed tomography (CT) navigation system (SIRIO) and to compare it with the standard CT-guided technique. (2) Methods: Lung RFA and MWA were performed with an augmented reality C...
Article
Full-text available
The pericapsular nerve group (PENG) block is a novel regional anaesthesia technique that aims to provide hip analgesia with preservation of motor function, although evidence is currently lacking. In this single‐centre, observer‐masked, randomised controlled trial, patients undergoing total hip arthroplasty received pericapsular nerve group block or...
Article
Lumbar epidural infiltration (EI) is a feasible procedure performed in pain therapy. Even though epidural analgesia is widely applied, it remains a blind technique, based on the operator’s hand sensations, and it is associated with significant failure rate and several potential complications. Compuflo® (Compuflo, Milestone Scientific, Livingston, N...
Article
Temperature monitoring inside tissue undergoing minimally invasive thermal ablation is a primary goal to improve the clinical outcomes. Existing techniques for temperature measurements, classified as invasive or contactless, have limited clinical practice applications due to several practical issues. Fiber Bragg grating sensors (FBG) can be a valid...
Conference Paper
Instrumented objects (e.g., smart mattress) are attractive technologies in the field of long-term vital signs monitoring because of their unobtrusiveness. Among the existing sensors that can be employed to develop smart mattress, Fiber Bragg grating sensors (FBGs) are one of the most promising ones. Their particular characteristics (i.e., high- sen...
Article
Full-text available
Background: Spinal anesthesia is a commonly performed procedure with unpredictable difficulty. The objective of this study is to predict a difficult lumbar spinal anesthesia with clinical elements that are easy to collect. Methods: A questionnaire-based, observational study named NBA, conducted from February 2018 to June 2018. The questions rega...
Article
Background: The detection of epidural space is usually performed by the technique of loss of resistance (LOR) without technological support, although there are few commercial options. In this work, we aimed to assess the feasibility of a new, non-invasive, mechatronic system for LOR detection in clinical settings. The system allows monitoring the...
Article
The performance of a precise and safe peripheral nerve blockade (PNB) can currently rely on the aid of the ultrasounds and nerve stimulators. The injection pressure monitoring may be beneficial to perform a safer procedure. This review focuses on the pressures measured during PNB among studies conducted on animal, and human models. From a deep rese...
Article
Full-text available
In Italy, chronic pain affects more than a quarter of the population, whereas the average European prevalence is 21%. This high prevalence might be due to the high percentage of Italian people who do not receive treatment, even after the passing of law 38/2010 (the right to access pain management in Italy), which created a regional network for the...
Article
Full-text available
Contrast-induced acute kidney injury (CI-AKI) is a serious complication during percutaneous coronary interventions (PCI). Currently, the diagnosis of CI-AKI relies on serum creatinine (SCr) that is however affected by several limitations potentially leading to delayed or missed diagnoses. In this study we examined the diagnostic accuracy of a “beds...
Data
Excel database with demographic and clinical features of the enrolled population. (XLSX)
Article
Full-text available
Over the last decades epidural analgesia has gathered research interest and broad clinical acceptance. In this procedure, the detection of the epidural space is pivotal to avoid major complications. Although, some systems for supporting the anaesthetist in the epidural space detection are commercially available, this difficult procedure is often pe...
Article
Full-text available
Colistin is a last resort antibiotic to treat multidrug-resistant Gram-negative bacteria infections. Colistin is administered intravenously in the form of its inactive prodrug colistin methanesulfonate (CMS). For patients with acute kidney impairment and continuous renal replacement therapy high extracorporeal clearance may cause a substantial remo...
Article
Full-text available
Purpose: Evaluate the efficacy and safety of MESNA (sodium 2-mercaptoethanesulfonate) injection into the epidural space in the FBSS. Methods: We designed a prospective phase II longitudinal study. Six consecutive patients were enrolled. Patients underwent one peridural injection per week for 3 weeks. NRS and ODI were investigated before and 48 h...
Article
The detection of epidural space is usually performed by the technique of loss of resistance (LOR) without technological support, although there are few commercial options. We sought to design and develop a new noninvasive system able to detect the LOR without any changes to the conventional procedure. It allows detecting the LOR by a custom made al...
Conference Paper
During recent decades epidural analgesia has gained widespread recognition in many applications. In this complex procedure, anaesthetist uses a specific needle to inject anesthetic into the epidural space. It is crucial the appropriate insertion of the needle through inhomogeneous tissues placed between the skin and the epidural space to minimize a...
Conference Paper
Introduction: Treatment of vestibular schwannomas presents many controversial aspects, from the indication to the selection of the best treatment option. In the era of stereotactic radiotherapy, microsurgery has to be competitive in terms of providing the best chances of functional preservation and complete tumor removal. The two most commonly used...
Conference Paper
Epidural blockade procedures have gained large acceptance during last decades. However, the insertion of the needle during epidural blockade procedures is challenging, and there is an increasing alarming risk in accidental dural puncture. One of the most popular approaches to minimize the mentioned risk is to detect the epidural space on the base o...
Article
Background Pressures (Pe) exerted by bronchial blockers on the inner wall of the bronchi may cause mucosal ischaemia. Our aims were as follows: (i) to compare the intracuff pressure (Pi) and Pe exerted by commercially available bronchial blockers in an in vitro and an ex vivo model; (ii) to investigate the influence of both the inflated intracuff v...
Article
Full-text available
Background: Implanted ports are frequently used for patients with cancer who require IV chemotherapy. In addition to verbal communication with healthcare providers, patients with cancer may benefit from written information. Objectives: This pre/post study evaluated the effectiveness of an informational booklet by improving knowledge about ports...
Poster
Abstract published on-line in European Cancer Congress 2015 Abstract book - a European Journal of Cancer Supplement, 51(Supplement 3):S1-S810 (S256).
Conference Paper
Bronchial blockers (BBs) allow occluding the bronchial duct and collapsing the “dependent” lung in a number of thoracic surgery. The occlusion is obtained through a cuff that, inflated with a proper air volume, exerts a pressure, Pe, on the inner wall of the mainstem bronchus. In this work a measurement chain, based on two piezorestistive force sen...
Article
Providing patients with written information about totally implantable access ports (TIAPs) is recommended during the pre-implantation period to reduce anxiety and to help recalling information. No study tested the effectiveness of information about TIAP neither with oral communication nor with booklets. This study aimed at evaluating the effectiven...
Article
Full-text available
Effective management of the airway is a priority in resuscitation efforts and a central issue in emergency medicine for providing ventilation and oxygenation in critically ill patients. Compared to the controlled conditions of the operating theatre, airway management in the emergency department is more difficult than in other circumstances; the pat...
Article
Full-text available
In our daily practice in intensive care unit, one of the “cornerstones” is to achieve adequate sedation for every patient. Intensive care unit (ICU) patients are often sedated, and a good hypnotic monitoring is important to assure an optimal level of sedation for every patient. Sedation monitoring can be achieved using subjective or objective metho...
Article
A frequent complication of totally implantable central venous access devices (TIVADs) is withdrawal occlusion. We describe a case of rare dysfunction of TIVADs: blood withdrawal was possible, whereas infusion was not. A further investigation demonstrated that during infusion, a silicone core, probably produced by hypodermic needle puncture, occlude...
Article
The gold standard methods to measure cardiac output (CO) are invasive and expose the patient to high risks of various complications. The aim of this study is to assess an innovative non-invasive method for CO monitoring in mechanically ventilated patients after cardiac surgery and its agreement with values obtained by thermodilution technique. Cont...
Article
Background. The endoscopic endonasal transclival approach (EETCA) is a minimally-invasive technique allowing a direct route to the base of implant of clival lesions with reduced brain and neurovascular manipulation. On the other hand, it is associated with potentially severe complications related to the difficulties in reconstructing large skull ba...
Book
Full-text available
Il dolore è un segnale d'allarme con cui il nostro organismo si segnala che qualcosa non va. Ciascuno di noi vive il dolore in modo diverso. Il significato che le persone attribuiscono al dolore e alle situazioni che lo provocano dipende dalla cultura e dalle conoscenze possedute, ma anche dalle credenze personali. Questa interpretazione influenza...
Article
Background: Despite a general ethical basis for justification, palliative sedation (PS) still has many controversial aspects that require further discussion and clarification. From a practical standpoint, moreover, there is considerable variability in the clinical procedure and an increasingly uncertain boundary between PS and involuntary euthanasi...
Article
Background: Forces applied on oropharyngeal soft tissues by direct laryngoscopy may cause damage to the patients. The aim of this study was to measure the forces applied during the manoeuvres to achieve glottis visualization and tracheal intubation, comparing direct laryngoscopy and videolaryngoscopy in vivo. Methods: Thirty adult patients (ASA...
Article
Background: Treatment of vestibular schwannomas presents many controversial aspects, from the indication to the selection of the best treatment option. In the era of stereotactic radiotherapy, microsurgery has to be competitive in terms of providing the best chances of functional preservation and complete tumor removal. The two most commonly used...
Chapter
Palliative sedation is a medical procedure in which consciousness is reduced or abolished, as the only therapeutic resource to relieve refractory symptoms that are intolerable for the patient. It is carried out through gradual titration of a sedative accompanied by periodic monitoring of the patient’s vital signs, level of sedation, and degree of s...
Article
Full-text available
Background The widespread of hallux valgus surgery in a day care setting enhanced the role of regional anaesthesia in the last few years. Sciatic nerve block at popliteal fossa has been shown to provide safe and effective analgesia. Our purpose was to compare the success rate and performance time of popliteal block during resident’s training for re...
Article
A non-invasive method to estimate cardiac output (CO) in mechanically ventilated patients, based on prolonged expiration, has been previously described. With the aim to assess its performances, we prospectively enrolled fifteen cardiac surgery patients, and compared the results obtained with the non-invasive method with the ones obtained using two...
Article
A non-invasive method for the estimation of cardiac output in mechanically ventilated patients is described. The method is based on prolonged expiration, and relies on measurement of gas concentrations and flow rate. A pneumatic system, with an ad hoc designed orifice resistance, has been made and experimentally characterized to adapt the breathing...