Mashhadi Ma

Mashhadi Ma
Zahedan University of Medical Sciences · Internal medicine

9.17
 · 
Professor of medicine

About

13
Publications
1,444
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196
Citations

Publications

Publications (13)
Article
Full-text available
Aim: MicroRNAs (miRNAs) are small noncoding RNAs that function as oncogene or tumor suppressors. The single nucleotide polymorphisms in miRNAs potentially can alter miRNA-binding sites on target genes as well as affecting miRNAs expression. The present study aimed to evaluate the impact of miR-608 rs4919510 C>G variant on breast cancer (BC) risk....
Article
Full-text available
Fas/Fas ligand (FasL) system is one of the key apoptotic signaling entities in the extrinsic apoptotic pathway. De-regulation of this pathway, i.e. by mutations may prevent the immune system from the removal of newly-formed tumor cells, and thus lead to tumor formation. The present study investigated the association between -1377 G/A (rs2234767) an...
Article
Full-text available
Fas/Fas ligand (FasL) system is one of the key apoptotic signaling entities in the extrinsic apoptotic pathway. De-regulation of this pathway, i.e. by mutations may prevent the immune system from the removal of newly-formed tumor cells, and thus lead to tumor formation. The present study investigated the association between -1377 G/A (rs2234767) an...
Article
Full-text available
Thalassemia is the most common monogenic disease in South-East of Iran. Despite the 70% reduction in Iranian thalassemia cases after thalassemia control comprehensive program, 601 affected babies were born in Sistan and Balouchistan Province, Iran from 2002 to 2010, so this study aims at investigating the causes of new thalassemia cases. Data from...
Article
Introduction: Esophagus cancer is most common GI malignancies in Zahedan. This investigation was undertaken to define the epidemiology, and prognostic factors relevant to patients with Esophagus cancer in this region. Methods: We did a retrospective review of 175 patients with Esophagus cancer who presented to Ali Ebne Abitaleb Hospital and Khatam...
Article
Background: Patients with rheumatoid arthritis (RA) are at increased risk of developing low bone mineral density. The aim of the present study was to compare the bone mineral density of Iranian female RA patients with healthy controls. Materials and methods: In this case-control study, bone mineral density of 391 rheumatoid arthritis patients and 3...
Article
Introduction: suitable information of different cancers in special geographic areas can help define medical programs for treatment and screening of high-risk groups. Aims and Methods: The aim of this study is to present the frequency of cancers in Hospitals of the Zahedan. A comprehensive search was undertaken to survey and register all cases of ca...
Article
Introduction: Gastric cancer is the second most common GI malignancy in Zahedan. This investigation was undertaken to define the demographic, clinicopathological, and prognostic factors relevant to patients with gastric adenocarcinoma. Methods: We did a retrospective study of 100 patients with gastric cancer who had been at Ali Ebne Abitaleb Hospit...
Article
Full-text available
semj.sums.ac.ir/vol10/jul2009/88007.htm Abstract: Introduction: Hematologic malignancies can be associated with dysregulation of the immune system. There are some conflicting data regarding serum immunoglobulin levels in patients with such malignancies. Material and method: In order to evaluate the humoral immunity of the patients with hema-tologic...
Article
Background: Over 50% of patients with AML still relapse after autologous stem cell transplantation. We investigatedthe efficacy and feasibility of a new conditioning regimen consisting of a moderate dose of idarubicine plusconventional dose of oral busulfan in patients undergoing autologous transplantation without favorable cytogeniticstate and hig...
Article
Although chronic myelogenous leukemia in pregnancy is rare, its management and treatment is more difficult and complicated. Treatment of patients with chronic myelogenous leukemia in- cludes bone marrow transplantation, however in less than 30% of patients the donor's organ would be accepted. To this end, cyto- toxic therapy is considered as an alt...
Article
Background: Methotrexate (MTX) is one of the most widely used anti-cancer agents. The administration of ahigh-dose methotrexate (HD-MTX) can be safely administered to patients with normal renal function, using alkalinization,hydration, and pharmacokinetically guided leucovorin (LV) rescue. The aim of this study was to determinethe side effects of H...
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