Masakazu Ide

Masakazu Ide
National Rehabilitation Center for Persons with Disabilities

Ph. D

About

43
Publications
3,084
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254
Citations
Introduction
Research interests in our team is abnormal perceptual functioning in autism linked to pathological sensory processing. In addition, we sought to elucidate neural basis of motor impairments of them focusing on atypical GABAergic signalling using MRspectroscopy.
Additional affiliations
July 2017 - September 2017
National Rehabilitation Center for Persons with Disabilities
Position
  • Investigator

Publications

Publications (43)
Article
Full-text available
Many individuals with autism spectrum disorder (ASD) have symptoms of sensory hypersensitivity. Several studies have shown high individual variations in temporal processing of tactile stimuli. We hypothesized that these individual differences are linked to differences in hyper-reactivity among individuals with ASD. Participants performed two tasks...
Article
Full-text available
The human brain is sensitive to incoming sensory information across multiple time scales. Temporal scales of information represented in the brain generally constrain behavior. Despite reports of the neural correlates of millisecond timing, how the human brain processes sensory stimuli in the sub-second range (≤100 ms) and its behavioral implication...
Article
Full-text available
Despite numerous reports of abnormalities in limb motor controls in spatial orientation in individuals with autism spectrum disorder (ASD), the underlying mechanisms have not been elucidated. We studied the influence of allocentric coordinates on ongoing reaching movements, which has been reported to strongly affect the reaching movements of typica...
Article
Atypical processing of stimulus inputs across a range of sensory modalities in autism spectrum disorder (ASD) are widely reported. Sensory processing is known to be influenced by bodily internal states such as physiological arousal and anxiety. Since a sizeable proportion of ASD reportedly have co‐morbid anxiety disorder that are linked with dysreg...
Article
Full-text available
Studies have proposed that individuals with autism spectrum disorder (ASD) can be divided into several subtypes depending on their sensory features. However, consideration of social communication features is also crucial for configuring ASD subtypes, because social and sensory features are tightly interrelated. In this study, we asked Japanese indi...
Article
Full-text available
Individuals with autism spectrum disorder (ASD) have atypical sensory processing, particularly when sensory stimuli are delivered from different modalities with a temporal lag of subseconds. Previous studies have suggested that individuals with ASD require a longer temporal lag to judge temporal orders of successive audiovisual stimuli than neuroty...
Preprint
and keywords Generally, when individuals attempt to move two limbs rhythmically in the opposite direction (e.g., flex the left hand and extend the left foot along the sagittal plane), the movements tend to be instead performed in the same direction. This phenomenon, known as directional constraint, can be harnessed to examine the difficulties in mo...
Preprint
Studies have proposed that individuals with autism spectrum disorder (ASD) can be divided into several subtypes depending on their sensory features. However, consideration of social communication features is also crucial for configuring ASD subtypes, because social and sensory features are tightly interrelated. In this study, we asked Japanese indi...
Article
Full-text available
Rubber hand illusion (RHI), a kind of body ownership illusion, is sometimes atypical in individuals with autism spectrum disorder; however, the brain regions associated with the illusion are still unclear. We previously reported that mice responded as if their own tails were being touched when rubber tails were grasped following synchronous strokin...
Preprint
Full-text available
Atypical processing of stimulus inputs across a range of sensory modalities in autism spectrum disorders (ASD) are widely reported. Sensory processing is known to be influenced by bodily internal states such as physiological arousal and anxiety. Since a sizeable proportion of ASD individuals reportedly have co-morbid anxiety disorders that are link...
Preprint
Full-text available
Background Researchers have been focused on perceptual characteristics of autism spectrum disorder (ASD) in terms of sensory hyperreactivity. Previously, we demonstrated that temporal resolution, which is the accuracy in differentiating the order of two successive vibrotactile stimuli, is associated with the severity of sensory hyperreactivity (Ide...
Article
Full-text available
In cognitive science, self-disturbance in schizophrenia is regarded as an unusual sense of body ownership. This study examined the possibility of discriminating self-disturbance between patients with schizophrenia and healthy individuals using the rubber hand illusion (RHI). We evaluated RHI in inpatients with schizophrenia with mainly negative sym...
Preprint
Full-text available
Despite numerous reports of abnormalities in limb motor controls in spatial orientation in individuals with autism spectrum disorder (ASD), the underlying mechanisms have not been elucidated. We studied the influence of allocentric coordinates on ongoing reaching movements, which has been reported to strongly affect the reaching movements of typica...
Article
Full-text available
Several motor disabilities accompanied with autism spectrum disorder (ASD) are widely known despite limited reports of underlying neural mechanisms. Gamma-aminobutyric acid (GABA) levels in the motor-related cortical areas modulate several motor performances in healthy participants. We hypothesized that abnormal GABA concentrations in the primary m...
Article
Individuals with autism spectrum disorder (ASD) often exhibit abnormal processing of sensory inputs from multiple modalities and higher-order cognitive/behavioral response to those inputs. Several lines of evidence suggest that altered γ-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the brain, is a central characteristic of the...
Article
Full-text available
Prediction is the process by which future events are anticipated based on past events; in contrast, postdiction is the retrospective interpretation of past events based on latter, more recent events. The prediction and postdiction are suggested to be similar based on theoretical models. Previous studies suggest that prediction is impaired in indivi...
Article
In: Volkmar F. (eds) Encyclopedia of Autism Spectrum
Article
Full-text available
Body ownership is a fundamental aspect of self-consciousness. Illusion of body ownership is caused by updating body representation through multisensory integration. Synchronous visuotactile stimulation of a hand and rubber hand leads to illusory changes in body ownership in humans, but this is impaired in individuals with autism spectrum disorder (...
Article
Full-text available
Crossmodal studies have reported not only facilitatory but also inhibitory perceptual interactions. For instance, tactile stimulation to the index finger of a hand leads to the degradation of visual discrimination performance (touch-induced visual suppression, TIVS). It has been suggested that the magnitude of TIVS depends on the spatial congruency...
Article
Full-text available
Recent translational studies using mice have contributed toward elucidating the neural, genetic, and molecular basis of social communication deficits. Nevertheless, many components of visual processes underlying mice sociality remain unresolved, including perception of bodily-movement. Here, we aimed to reveal the visual sensitivity of mice to info...
Data
An example of Biological motion movie clip.
Data
An example of Scrambled motion movie clip.
Article
Most individuals with autism-spectrum disorders have hypersensitivity/hyposensitivity to various types of sensory stimuli. Although several hypotheses such as higher sensitivity to stimuli, alterations in brain structure and function, and dysfunction of inhibitory systems at the molecular level have been suggested, there is no convincing evidence....
Article
Full-text available
Oxytocin is a hormone of the posterior pituitary that promotes lactation, maternal bonding, and birth. Recent studies have shown that oxytocin may modulate social recognition in both sexes, and thus it may be related to empathy. Brain regions that are associated with social recognition and empathy (e.g., the insular cortex) are activated in the rub...
Article
Full-text available
Crossmodal studies have demonstrated inhibitory as well as facilitatory neural effects in higher sensory association and primary sensory cortices. A recent human behavioral study reported touch-induced visual perceptual suppression (TIVS). Here, we introduced an experimental setting in which TIVS could occur and investigated brain activities underl...
Article
Significance statement: To explore the manner in which the ownership of body parts is experienced, this study specifically used the rubber hand illusion (RHI), in which self-consciousness can be extended out of one's own body. Accumulating empirical evidence supports the existence of this concept in humans and nonhuman primates, but it remains unc...
Article
Full-text available
In a rubber hand illusion (RHI) task, synchronous brush stroking of a rubber hand and a participant’s hidden hand induces body ownership of the rubber hand. The effects of spatial distances and temporal lags on the RHI have been extensively examined; however, the effect of periodicity of the stimuli on illusory body ownership has not been examined....
Article
Persons with high autistic traits showed diverse reactions as to their multisensory integration, whereas neurotypical persons adequately integrate visual and tactile information. Successive visual stimuli sometimes interfere ordering of successive tactile stimuli. Presentation of a hand-shaped object would affect the interference. Besides, its asso...
Article
Full-text available
In a single modality, the percept of an input (e.g., voices of neighbors) is often suppressed by another (e.g., the sound of a car horn nearby) due to close interactions of neural responses to these inputs. Recent studies have also suggested that close interactions of neural responses could occur even across sensory modalities, especially for audio...
Article
Full-text available
An input (e.g., airplane takeoff sound) to a sensory modality can suppress the percept of another input (e.g., talking voices of neighbors) of the same modality. This perceptual suppression effect is evidence that neural responses to different inputs closely interact with each other in the brain. While recent studies suggest that close interactions...
Article
Full-text available
In the rubber-hand illusion (RHI), when an actual hand hidden from view and a rubber hand in view are simultaneously stimulated, participants mistakenly perceive tactile sensation as arising from the rubber hand, not from the actual hand. Some studies have revealed that the magnitude of RHI decreases when the actual and rubber hand are incongruent...
Article
Full-text available
Perceptual systems can distinguish among a variety of inputs in the temporal domain, including even different sensory inputs. This process has been investigated mainly by using a temporal task (temporal order judgment: TOJ). For example, studies have reported estimated critical limits (just noticeable difference: JND) of the TOJ between a visual st...
Article
Purpose: Research on the rubber hand illusion has ever emphasized the role of visual information in locating a tactile sensation on the rubber hand. However, auditory information also serves to locate the tactile sensation along with visual information. Even without visual information, the tactile sensation is produced by a tactile stimulus present...

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Projects

Projects (2)
Project
Funding source: Japanese Society for the Promotion of Science: Challenging Research (Exploratory)
Project
To elucidate underlying mechanisms of social deficits and aberrant tactile sensory processing in autism spectrum disorders by using animal models. (Funding source: Japanese Society for the Promotion of Science: Grant-in-Aid for JSPS Research Fellow)