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Introduction
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Education
January 2012 - December 2015
September 2009 - November 2011
September 2008 - June 2009
Publications
Publications (8)
Axonally expressed neuregulin 1 (NRG1) type III is a transmembrane protein involved in various neurodevelopmental processes, including myelination and Schwann cell migration. NRG1 type III has one transmembrane domain and a C-terminal extracellular segment, which contains an epidermal growth factor homology domain. Little is known, however, about t...
The multilayered myelin sheath displays a biologically unique environment. It is present in the central and peripheral nervous systems, where it isolates long axonal segments and enables fast saltatory conduction. Being lipid-rich and containing highly abundant, specifically localized proteins, the structure and genesis of myelin on the molecular s...
Three derivatives of 5-iodouracil were prepared, and their complexation properties, supplemented by 5-iodouracil under the same conditions, were studied with and without halogen bond acceptors in N,N-dimethylformamide, N,N-diethylformamide, N-methylformamide, formamide, dimethylsulfoxide, and water. The intermolecular halogen and hydrogen bonding i...
The myelin sheath is a unique membrane, tightly wrapped around selected axons in the vertebrate nervous system. The multilayered myelin proteolipid membrane contains a specific set of proteins, many of which share no homology with other known proteins. We are interested in the structure, function, interactions, and dynamics of myelin proteins and u...
Juxtanodin, also called ermin, is an F-actin-binding protein expressed by oligodendrocytes, the myelin-forming cells of the central nervous system. While juxtanodin carries a short conserved F-actin-binding segment at its C terminus, it otherwise shares no similarity with known protein sequences. We carried out a structural characterization of reco...
Supplementary Figure 1
In this work the approach for producing thin-layer chromatographic plates with monolithic layer of silica was proposed. The conditions of silica monolith synthesis were optimized by investigation of effects of different catalysts on the properties of obtained materials and addition of drying control chemical additive. The carrier for silica monolit...