Martyna Molak

• PhD
• Researcher at Polish Academy of Sciences

Background Treponemal diseases are a significant global health risk, presenting challenges to public health and severe consequences to individuals if left untreated. Despite numerous genomic studies on Treponema pallidum and the known possible biases introduced by the choice of the reference genome used for mapping, few investigations have addresse...

The question, whether a dog is a dog or rather a wolf, is highly debated in the field of zooarchaeology, paleogenetic, and stable isotopes. Recent evidence points towards an onset of wolf domestication in south-western Germany and northern Switzerland at around 16 to 15,000 years ago. Regarding diet of wolves and potential dogs, both groups fed on...

The question, whether a dog is a dog or rather a wolf, became recently highly debated. Recent evidence points towards an onset of domestication at around 16 to 15,000 years ago including an intriguing example of the Kesslerloch cave (CH), where beside wolf remains, one large canid has been morphologically and genetically confirmed as dog. Regarding...

A Correction to this paper has been published: https://doi.org/10.1038/s41586-021-03328-2.

Dogs are known to be the oldest animals domesticated by humans. Although many studies have examined wolf domestication, the geographic and temporal origin of this process is still being debated. To address this issue, our study sheds new light on the early stages of wolf domestication during the Magdalenian period (16–14 ka cal BP) in the Hegau Jur...

Tiwanaku was a civilization that flourished in the Lake Titicaca Basin (present-day Bolivia) between 500 and 1000 CE. At its apogee, Tiwanaku controlled the lake’s southern shores and influenced certain areas of the Southern Andes. There is a considerable amount of archaeological and anthropological data concerning the Tiwanaku culture; however, ou...

The territory of former Eastern Poland formed part of the wider ethno-cultural frontier developed between Polish Mazovia and Turovian Rus’ and Volhynia between the second half of the 10th and the second half of the 13th century. Overall, its mosaic-like cultural landscape was formed by the traditional, pagan background and Christian influences refl...

Yersinia pestis , the causative agent of plague, has been prevalent among humans for at least 5000 years, being accountable for several devastating epidemics in history, including the Black Death. Analyses of the genetic diversity of ancient strains of Y. pestis have shed light on the mechanisms of evolution and the spread of plague in Europe. Howe...

The maritime expansion of Scandinavian populations during the Viking Age (about ad 750–1050) was a far-flung transformation in world history1,2. Here we sequenced the genomes of 442 humans from archaeological sites across Europe and Greenland (to a median depth of about 1×) to understand the global influence of this expansion. We find the Viking pe...

Background: Recent advances in sequencing have facilitated large-scale analyses of the metagenomic composition of different samples, including the environmental microbiome of air, water, and soil, as well as the microbiome of living humans and other animals. Analyses of the microbiome of ancient human samples may provide insights into human health...

The cave bear (Ursus spelaeus) is one of the Late Pleistocene megafauna species that faced extinction at the end of the last ice age. Although it is represented by one of the largest fossil records in Europe and has been subject to several interdisciplinary studies including palaeogenetic research, its fate remains highly controversial. Here, we us...

The Viking maritime expansion from Scandinavia (Denmark, Norway, and Sweden) marks one of the swiftest and most far-flung cultural transformations in global history. During this time (c. 750 to 1050 CE), the Vikings reached most of western Eurasia, Greenland, and North America, and left a cultural legacy that persists till today. To understand the...

Significance The majority of viral genomic sequences available today are fewer than 50 years old. Parvovirus B19 (B19V) is a ubiquitous human pathogen causing fifth disease in children, as well as other conditions. By isolating B19V DNA from human remains between ∼0.5 and 6.9 thousand years old, we show that B19V has been associated with humans for...

Egypt, located on the isthmus of Africa, is an ideal region to study historical population dynamics due to its geographic location and documented interactions with ancient civilizations in Africa, Asia and Europe. Particularly, in the first millennium BCE Egypt endured foreign domination leading to growing numbers of foreigners living within its bo...

Nuclear capture results

Supplementary Figures, Supplementary Tables, Supplementary Notes and Supplementary References

Comparison of mitochondrial and nuclear Haplogroups. As the nuclear results do not have any specific enrichment applied for mitochondrial DNA retrieval, there are cases where the position was either not covered (yellow) or covered with less than 3 reads (red). Matching mutations were marked in green respectively between both captures.

Results of the genetic distance computation with Arlequin between 56 populations from Europe, Africa, the middle East, Asia and the Ancient Egyptian metapopulation investigated in this study.

Sample Name

Results and details of a population continuity test between our investigated three ancient Egyptian populations and modern populations from Egypt and Ethiopia in the respective region.

We are writing in response to a recent critique by Emerson & Hickerson (2015), who challenge the evidence of a time-dependent bias in molecular rate estimates. This bias takes the form of a negative relationship between inferred evolutionary rates and the ages of the calibrations on which these estimates are based. Here, we present a summary of the...

Mitochondrial genomes represent a valuable source of data for evolutionary research, but studies of their short-term evolution have typically been limited to invertebrates, humans and laboratory organisms. Here we present a detailed study of 12 mitochondrial genomes that span a total of 385 transmissions in a well-documented 50-generation pedigree...

The Montagu’s harrier (Circus pygargus) is a long-distance migratory raptor, breeding in Europe and Western Asia and wintering in sub-Saharan Africa. The population of the species has declined in Europe during the twentieth century, and Montagu’s harrier is red-listed in many European countries as declining or threatened. The main aims of the study...

Evolutionary timescales can be estimated from genetic data using the molecular clock, often calibrated by fossil or geological evidence. However, estimates of molecular rates in mitochondrial DNA appear to scale negatively with the age of the clock calibration. Although such a pattern has been observed in a limited range of data sets, it has not be...

a b s t r a c t Cave bears are among the most well known extinct Pleistocene mammals. Their biogeography and taxonomy, along with the factors that led to their extinction, have been subject to long-standing con-troversy. Here, we reconstruct the phylogeography as well as the temporal and spatial population dy-namics of cave bears across their range...

The common practice of resettlement and the development of administrative and ceremonial systems shaped the population landscape of the Andean region under the Inca rule. The area surrounding Coropuna and Solimana volcanoes, in the Arequipa region (Peru), carried a high-density, multiethnic population. We studied the genetic variation among three p...

Studies of DNA from ancient samples provide a valuable opportunity to gain insight into past evolutionary and demographic processes. Bayesian phylogenetic methods can estimate evolutionary rates and timescales from ancient DNA sequences, with the ages of the samples acting as calibrations for the molecular clock. Sample ages are often estimated usi...

Relaxed molecular clocks allow the phylogenetic estimation of evolutionary timescales even when substitution rates vary among branches. In analyses of large, multigene data sets, it is often appropriate to use multiple relaxed-clock models to accommodate differing patterns of rate variation among genes. We present ClockstaR, a method for selecting...

In recent years, ancient DNA has increasingly been used for estimating molecular timescales, particularly in studies of substitution rates and demographic histories. Molecular clocks can be calibrated using temporal information from ancient DNA sequences. This information comes from the ages of the ancient samples, which can be estimated by radioca...

The growth of ancient DNA research has offered exceptional opportunities and raised great expectations, but has also presented some considerable challenges. One of the ongoing issues is the impact of post-mortem damage in DNA molecules. Nucleotide alterations and DNA strand breakages lead to a significant decrease in the quantity of DNA molecules o...

The 13th Conference on Australasian Vertebrate Evolution Palaeontology and Systematics (CAVEPS) took place in Perth, Western Australia, from 27 to 30 April 2011. This biennial meeting was jointly hosted by Curtin University, the Western Australian Museum, Murdoch University and the University of Western Australia. Researchers from diverse disciplin...

In the early 1990s, when studies of ancient DNA became possible, new perspectives of analyzing archaeological data also developed. Nowadays, because the methodology related to ancient DNA research is well developed, it has been used to reveal several aspects of human history and interaction. Here we review the basic concepts, methodologies, and rec...