Martin Sames

Martin Sames
University J.E. Purkyne, Masaryk Hospital, Usti nad Labem · Neurosurgery

MD, PhD

About

207
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Publications

Publications (207)
Article
Full-text available
Lumbar spine stenosis (LSS) typically manifests with neurogenic claudication, altering patients’ gait. The use of optoelectronic systems has allowed clinicians to perform 3D quantitative gait analysis to quantify and understand these alterations. Although several authors have presented analysis of spatiotemporal gait parameters, data concerning kin...
Article
BACKGROUND This report depicts a rare case of acutely developed urinary retention as well as sensory and motor disturbances caused by formation of a large hematoma within the piriformis muscle, which caused compression of nerves within the suprapiriform and infrapiriform foramina, thus imitating cauda equina syndrome. Although cases of acute lumbos...
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Study Design Prospective randomized controlled trial. Objectives Adjustment of endotracheal tube cuff pressure (ETCP) in anterior cervical discectomy and fusion (ACDF) may influence the incidence of complications such as recurrent laryngeal nerve palsy (RLNP), hoarseness, and dysphagia. Methods The prospective randomized controlled trial was desi...
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Background: Sacroiliac joint (SIJ) dysfunction is a chronic painful condition responsible for up to 30% of back pain. Treatment modalities include physiotherapy, intraarticular analgesic injections, ablation techniques or SIJ fusion. The severity of SIJ dysfunction is commonly assessed via subjective pain or disability scales. Quantitative gait an...
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Background An indication for selective shunting during carotid endarterectomy (CEA) is based on monitoring during a procedure. Cerebral oximetry (CO) using near-infrared spectroscopy (NIRS) may be a simple technique, but its relevance during CEA, especially with respect to cutoff values indicating shunt implantation, still needs to be elucidated....
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Treatment of aggressive glioblastoma multiforme (GBM) must be based on very precise histological and molecular diagnostic of GBM type. According to the WHO guidelines, only tissue biopsy is a relevant source of cellular material evaluated in the diagnostic process to specify the tumor features. Nevertheless, obtaining a GBM biopsy is complicated an...
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Carotid micro-endarterectomies (CEA) are common surgical procedures pursued to achieve revascularization of carotid arteries when occluded partially or fully by an atherosclerotic plaque. As with any surgical procedure, associated complications exist in small percentage of the cases. These can include blood flow limitation due to an insufficient ar...
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Extravasation of blood in the central nervous system (CNS) represents a very strong damaged associated molecular patterns (DAMP) which is followed by rapid inflammation and can participate in worse outcome of patients. We analyzed cerebrospinal fluid (CSF) from 139 patients after the CNS hemorrhage. We compared 109 survivors (Glasgow Outcome Score...
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Gas gangrene is a rare and potentially fatal surgical complication, most often associated with contaminated traumatic wounds or more rarely following cases of abdominal surgery. The following article describes a case of gas gangrene in the right lower limb of a 34-year-old patient following an elective posterior tibial tendon transfer. The surgery...
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The world currently faces the novel severe acute respiratory syndrome coronavirus 2 pandemic. Little is known about the effects of a pandemic on non-elective neurosurgical practices, which have continued under modified conditions to reduce the spread of COVID-19. This knowledge might be critical for the ongoing second coronavirus wave and potential...
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Aim: The aim of our work was retrospective evaluation of the resection extent of predicted and ongoing low-grade glioma (LGG) surgeries. Furthermore, we evaluated the behavior of defined residual tumors after subsequent oncological treatment in case of partial and subtotal resections. Patients and methods: We evaluated a series of our 37 patients o...
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Hemodynamic parameters play a significant role in the development of intracranial aneurysms and their time-depending changes during a prolonged follow-up period could lead to an increasing risk of rupture or to aneurysm rupture. The characteristics of these changes could bring significant information about the development of aneurysms and their rup...
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Background: Main objective of this study was to determine whether Hounsfield units (HU) measured in three areas of the axis correlate with successful fusion in patients with type II and shallow type III C2 fractures undergoing anterior odontoid screw osteosynthesis (AOSF). Methods: Forty-five patients with C2 fractures treated via AOSF were anal...
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Treatment of complex aneurysms often requires additional surgical tools including the use of the extra-intracranial (EC-IC) bypass. The following report depicts the utilization of the EC-IC bypass in treating a dissecting aneurysm several hours after a salvage emergent evacuation of an acute subdural hematoma via decompressive craniectomy (DC). Pre...
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Brain ischemia after central nervous system (CNS) bleeding significantly influences the final outcome of patients. Catalytic activities of aspartate aminotransferase (AST) in the cerebrospinal fluid (CSF) to detect brain ischemia were determined in this study. The principal aim of our study was to compare the dynamics of AST in 1956 CSF samples col...
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Background: Hemangioblastomas are histologically benign tumors with a variable degree of morbidity and mortality based on various factors, including their anatomical location. The following paper illustrates a unique approach of combined therapy of a brainstem hemangioblastoma (HB) not associated with von Hippel-Lindau disease (vHLd) located in th...
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Cerebral vasospasm and subsequent delayed ischemic neurological deficit is a typical sequela of acute subarachnoid hemorrhage after aneurysm rupture. The occurrence of vasospasms after uncomplicated surgery of an unruptured aneurysm without history of suspected rupture is extremely rare. The pathogenesis and severity of cerebral vasospasms is typic...
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Objectives To evaluate cerebral hemodynamic, metabolic and anatomic changes occurring in patients with unilateral occlusion of the internal carotid artery (ICA).Materials and methodsTwenty-two patients with unilateral occlusion of ICA and twenty age and sex matched healthy subjects were included in the study. Single voxel proton magnetic resonance...
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Intracranial pseudoaneurysms (PSA) are scarcely presented in the literature. We describe the case of an intracranial PSA on the right anterior cerebral artery, which developed during the complicated surgical treatment of a ruptured right middle cerebral aneurysm. The pseudoaneurysm grew over time and was co-incidentally diagnosed 3 months after the...
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The knowledge of the microanatomy of brain stem perforating arteries can aid in the correct identifi cation of ischemic stroke lesions, explain and provide a proper anatomic description of syndromes associated with the brain stem lesions. The importance of such detailed knowledge is growing when considering the possibilities of acute reperfusion th...
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Introduction: Atlanto-occipital dissociation (AOD) is a rare and unstable injury of the craniocervical junction, associated with very high morbidity and mortality. The most common cause of this injury is high energy trauma with hyperextension of the cranium, such as car accidents. Due to specific anatomical predispositions, children and young adul...
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Introduction: Until recently, there was a lack of information on sagittal axis parameters of the cervical spine, its relationship to the global sagittal axis of the spine, and their possible implications for long-term clinical outcomes in patients following subaxial cervical spine surgery. The aim of the authors is to provide an overview of the is...
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Abstract Aim: Sacroiliac joint (SIJ) dysfunction is a chronic disorder, representing a signifi cant cause of lower back pain. This study aims to present an evidence-based systematic analysis of published literature concerning the surgical management of SIJ dysfunction within the last 10 years. Its main goal is to demonstrate the clinical effi cacy...
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Magnetic resonance imaging (MRI) plays a crucial role in the diagnosis and morphological analysis of peripheral nerve tumours (PNTs). In recent years, a number of novel MRI sequences such as MR neurography (MRN), diffusion tensor imaging (DTI) or MR tractography (MRT) have emerged extending the range of conventional MRI techniques. These advanced s...
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Background Facial paralysis is a severe disease. A wide variety of surgical procedures to facial nerve reconstruction are available. We demonstrate reinnervation after infratemporal end-to-end anastomosis following nerve rerouting and concomitant masseteric nerve transfer to the side of facial nerve trunk. Masseteric nerve transfer seems to have st...
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Facial paralysis is a severe disease and presents a formidable treatment challenge. A wide variety of surgical procedures are available with limited evidence. Major risk factors of suboptimal recovery include the duration of paralysis as well as higher age. In this paper, we demonstrate reconstruction of the facial nerve via an intratemporal end-to...
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OBJECTIVE: Silent and symptomatic cerebral infarctions occur in up to 34% of patients after carotid endarterectomy (CEA). This prospective study compared the risk of new brain infarctions detected by magnetic resonance imaging (MRI) in patients with internal carotid artery stenosis undergoing CEA with local anesthesia (LA) vs general anesthesia (G...
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Transethmoidal encephalocele is a rare condition in adult patients. It is usually diagnosed during childhood by cerebrospinal fluid (CSF) rhinorrhea, meningitis, a nasal mass, or seizures. We present a case of an adult woman with CSF rhinorrhea following resection of an occipital meningioma. The cribriform plate defect containing the encephalocele...
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This paper is a retrospective analysis of a 33 patient cohort with dia gnosis of glioblastoma multiforme treated us ing gam ma knife stereotactic radiation ther apy fol low ing surgical resection and fractionated radiation ther apy. Over al l, 35 stereotactic radiation procedures were performed. Within this group, we diff erentiated patients who be...
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Computational fluid dynamics have developed in the area of cerebrovascular diseases in recent years, especially in the research of intracranial aneurysms. The goal of most studies is to understand the pathophysiology of the initiation, growth and rupture of brain aneurysms and determine those risk hemodynamic parameters that lead to such processes....
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Aim: Development of an examination protocol for investigation of functional integrity and microstructural damage of peripheral nerves (PN) at different locations using diffusion tensor imaging (DTI). Consequently, we want to implement this protocol into clinical practice. Subjects and methods: We investigated 15 healthy volunteers and 15 patients w...
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The authors present a monocentric retrospective study of a group of 27 patients operated for non-ruptured brain arteriovenous malformation (AVM) during years 1999-2017. The aim was to compare our results with the results of larger international studies and to draw appropriate conclusions. All patients underwent radical resection of the AVM and thei...
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Computational fluid dynamics (CFD) has been studied as a tool for the stratification of aneurysm rupture risk. We performed CFD analysis in a patient operated on for a ruptured anterior communicating artery aneurysm. The point of rupture was identified during surgery. The aneurysm and blood vessels were segmented from computed tomography angiograph...
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Background: Rindopepimut (also known as CDX-110), a vaccine targeting the EGFR deletion mutation EGFRvIII, consists of an EGFRvIII-specific peptide conjugated to keyhole limpet haemocyanin. In the ACT IV study, we aimed to assess whether or not the addition of rindopepimut to standard chemotherapy is able to improve survival in patients with EGFRv...
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Introduction: Idiopathic normal pressure hydrocephalus (iNPH) is a disease with many unanswered questions. General effort is to find a simple and non-invasive diagnostic tool. Magnetic resonance imaging (MRI) is a topic for intensive research. Diffusion tensor imaging (DTI) is one of the MRI modalities. This examination can detect microstructural c...
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Background Clinically symptomatic vasospasm leading to delayed ischemic neurological deficits occurs in up to 30% of patients with subarachnoid hemorrhage (SAH). Vasospasm can result in a serious decline in clinical conditions of patients with SAH, yet the algorithm for vasospasm treatment and prevention remains unclear. Intra-arterial administrati...
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Background Posterior inferior cerebellar artery (PICA) aneurysms are an uncommon, heterogeneous group of aneurysms with poorer clinical outcomes compared to other intracranial aneurysms. We performed a multicenter retrospective study to analyse the outcome in a large series of patients treated with modern microsurgical and endovascular techniques....
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Cerebral vasospasm (CV) is a one of the main factors leading to high morbidity and mortality in patients with a severe subarachnoid hemorrhage. Biomarkers of early diagnosis of the vasospasm development and progression are still poorly understood. Use of microdialysis (MD) techniques combined with modern practices in metabolomic analysis can signif...
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Patients with symptomatic internal carotid artery (ICA) occlusion with haemodynamic impairment are at higher risk of ischaemic stroke, and they require treatment. There are two main options: the best medical treatment and an extracranial–intracranial bypass. The aims of this study are to analyse the 30-day and 2-year risk of stroke and death in pat...
Article
vod Netraumatické subarachnoidální krvácení (SAK) je akutní neurologický stav, jehož nejčastější příčinou je rup-tura mozkového aneuryzmatu. Při SAK dochází k vylití krve do subarachnoidálního prostoru na spodině mozku, který je normálně vyplněn mozkomíšním mokem (MMM). SAK je nejzávažnější formou mozkové mrtvice s roční incidencí 2–16/100 000 (cit...
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Background: Lateral or supine positions are the traditional positions for cranial tumorresections performed with an "awake" component. These positions are used effectively for patients with tumors adjacent to speech centers or located in the superior frontal or precentral gyrus respectively. However, these may be unsatisfactory for tumors in a clos...
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Background The effect of decompressive craniectomy on clinical outcomes in patients with refractory traumatic intracranial hypertension remains unclear. Methods From 2004 through 2014, we randomly assigned 408 patients, 10 to 65 years of age, with traumatic brain injury and refractory elevated intracranial pressure (>25 mm Hg) to undergo decompress...
Article
Objective: The temporal myofascial flap is a versatile option for the reconstruction of maxillofacial and skull base defects with minimal functional morbidity but with esthetic deformity at the donor site. Muscle atrophy is also a commonly encountered complication plaguing neurosurgeons after successful craniotomies and skull base approaches. The c...
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Objective: Aim of the study was to evaluate outcomes of the extra-intradural approach, to analyze complications and to assess the role of endovascular techniques and microsurgery from our experience and literature. Methods: Between 1999 and 2016, we treated 942 aneurysms, and there were 62 (6.6%) carotid-ophthalmic aneurysms. We used surgical clipp...
Article
Normal pressure hydrocephalus (NPH) is a disease of an elderly people. It is characterized by ventricular enlargement, normal pressure of the cerebrospinal fluid and progressive onset of gait disturbance, dementia and incontinency. The treatment is known (shunt surgery), but there are still controversies in the pathophysiology, thus in the optimal...
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Background: Disproportionately enlarged subarachnoid space hydrocephalus (DESH) findings on MRI were described as a prognostic factor for responsiveness to the treatment of idiopathic normal pressure hydrocephalus (iNPH). Our premise is that DESH could be associated with compression of the cerebral white matter. Microstructural changes can be iden...
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Purpose The aim of the study is to analyse the results of Leechavenvong’s transfer – long head triceps branch of radial nerve to axillary nerve neurotization. Matherial and methods Group of 5 patients (4 men, 1 woman, mean age 44, mean time from injury to surgery 5 months), who underwent Leechavenvong’s transfer in last two years was analysed. The...
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The presented case report describes the first use of adenosine-induced transient circulatory arrest in a patient undergoing cerebral aneurysm clipping in the Czech Republic. Short episodes of circulatory arrest improved surgical conditions (as assessed by the surgeon) without any apparent complications during surgery. The cumulative length of circu...
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Souhrn Gliomy limbického a paralimbického systému představují anatomicky a tím pádem i operač- ními přístupy unikátní skupinu mozkových nádorů. Mikrochirurgie v kombinaci s moderními perioperačními postupy zvyšuje šance na radikální odstranění těchto gliomů. Z hlediska lokalizace je dělíme do tří základních skupin: 1. gliomy inzuly, 2. amygdalohipp...
Article
Orbital tumors constitute a relatively rare and heterogeneous group of lesions, either originating in the orbit or with secondary extension into the bony orbital margins. Primary orbital tumors are scarcer and usually benign, while secondary tumors are usually malignant. Metastases may be found anywhere in the wall of the orbit or inside the orbit....
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Aim: The importance of early endarterectomy (CEA) for secondary stroke prevention in patients after transient ischaemic attack (TIA) inspired an analysis of our data and their correlation with generally accepted recommendations to ascertain whether any improvements are needed. Material and methods: 975 CEA were performed within a prospective study...