
Martin ReuterUniversity of Bonn | Uni Bonn · Institute of Psychology
Martin Reuter
Prof. Dr.
About
315
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Introduction
Additional affiliations
January 2007 - December 2012
January 2002 - December 2008
Publications
Publications (315)
Resection cavities, tumors, and other lesions can fundamentally alter brain structure and present as abnormalities in brain MRI. Specifically, quantifying subtle neuroanatomical changes in other, not directly affected regions of the brain is essential to assess the impact of tumors, surgery, chemo/radiotherapy, or drug treatments. However, only a l...
Imaginal exposure is a standard procedure of cognitive behavioral therapy for the treatment of anxiety and panic disorders. It is often used when in vivo exposure is not possible, too stressful for patients, or would be too expensive. The Bio-Informational Theory implies that imaginal exposure is effective because of the perceptual proximity of men...
Objectives
Artificial intelligence (AI) is thought to improve lesion detection. However, a lack of knowledge about human performance prevents a comparative evaluation of AI and an accurate assessment of its impact on clinical decision-making. The objective of this work is to quantitatively evaluate the ability of humans to detect focal cortical dys...
Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth of information about whether the loss of visual imagery in aphantasics affects their AM retrieval. The hippocampus is thought to be a crucial hub in a...
Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth of information about whether the loss of visual imagery in aphantasics affects their AM retrieval. The hippocampus is thought to be a crucial hub in a...
In clinical assessments and pain therapy, patients are asked to imagine themselves in pain. However, the underlying neuronal processes remain poorly understood. Prior research has focused on empathy for pain or reported small sample sizes. Thus, the present study aimed to promote the neurobiological understanding of self-referential pain imaginatio...
Chronic pain affects at least one in five individuals. Hence, adequate pain judgement is a vital interpersonal skill. Nonetheless, women often face treatment disparities due to biased assessments. Priorly, sex and gender (i.e., biological category vs. cultural representation) have not been investigated separately. Our study was thus designed to dis...
Aphantasia refers to reduced or absent visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth of information about whether the loss of visual imagery in aphantasics affects their AM retrieval. The hippocampus is thought to be a crucial hub in a...
This study aims to report human performance in the detection of Focal Cortical Dysplasias (FCDs), localized regions of malformed cerebral cortex, using a public dataset. Additionally, it defines a subset of this data as a representative testset to establish a baseline benchmark for the evaluation of automatic FCD detection approaches. The performan...
Aphantasia prohibits people from experiencing visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth of information about whether the loss of visual imagery in aphantasics affects their AM retrieval. The hippocampus is thought to be a crucial hu...
Aphantasia prohibits people from experiencing visual imagery. While most of us can readily recall decade-old personal experiences (autobiographical memories, AM) with vivid mental images, there is a dearth of information about whether the loss of visual imagery in aphantasics affects their AM retrieval. The hippocampus is thought to be a crucial hu...
Background
The relatively stable individual differences reflected in Grey's revised reinforcement sensitivity theory (rRST), with foundations in neurophysiology and learning theory, appear particularly applicable to the study of pain. However, remarkably little research has been conducted in this area. In acute pain, activation of the behavioural a...
The use of social networking sites is associated with objectification tendencies of the self and others. However, only few studies investigate how users actually perceive sexualizing content on Instagram. In a recent study, we showed that perceiving sexy Instagram posts as appropriate and less revealing goes along with self-sexualization in German...
Mental imagery enables people to simulate experiences in their minds without the presence of an external stimulus. The underlying biochemical mechanisms are poorly understood but there is vague evidence that dopamine may play a significant role. A better understanding at the biochemical level could help to unravel the mechanisms of mental imagery a...
Since numerous studies have impressively demonstrated the influence of personality traits on financial decision making, the question arises if genetic biological markers might underlie this association. The present study investigated exploratively the relationship between financial decision-making behavior and genetic markers of the dopaminergic sy...
Hippocampal volumetry is an essential tool in researching and diagnosing mesial temporal lobe epilepsy (mTLE). However, it has a limited ability to detect subtle alterations in hippocampal morphometry. Here, we establish and apply a novel geometry-based tool that enables point-wise morphometric analysis based on an intrinsic coordinate system of th...
Aphantasia and prosopagnosia are both rare conditions with impairments in visual cognition. While prosopagnosia refers to a face recognition deficit, aphantasics exhibit a lack of mental imagery. Current object recognition theories propose an interplay of perception and mental representations, making an association between recognition performance a...
The concept of “reserve” is defined as the resources being available to deal with adverse environmental influences on the human brain, and it has been proposed to account for the mismatch between brain pathology and clinical expression. New multidimensional approaches take into account the complexity and dynamic relation between the construct of re...
Focal cortical dysplasias (FCDs) are malformations of cortical development and one of the most common pathologies causing pharmacoresistant focal epilepsy. Resective neurosurgery yields high success rates, especially if the full extent of the lesion is correctly identified and completely removed. The visual assessment of magnetic resonance imaging...
Imaginal exposure is a standard procedure of cognitive behavioral therapy for the treatment of anxiety and panic disorders. It is often used when in vivo exposure is not possible, too stressful for patients, or would be too expensive. Peter Lang's Bio-Informational Theory implies that imaginal exposure is effective because of the perceptual proximi...
Empathy refers to an individual’s responses to the experiences of others. We hypothesised that mental imagery is related to self-reported empathy if assessed with verbal empathy questionnaires or vignettes and that this association disappears when visual tests are used. In study 1, we examined the association between imagery vividness and empathy i...
The catechol-O-methyltransferase (COMT) gene has arguably been the designated pain sensitivity gene for nearly two decades. However, the literature provides inconsistent evidence. We performed several meta-analyses including k = 31 samples and n = 4631 participants thereby revealing small effects of rs4680 on pain thresholds in fibromyalgia, headac...
It is well established that the e4 allele of the APOE gene is associated with impaired brain functionality and cognitive decline in humans at elder age. However, it is controversial whether and how the APOE e4 allele is associated with superior brain function among young healthy individuals, thus indicates a case of antagonistic pleiotropy of APOE...
Previous research demonstrated effects of visual imagery on search speed in visual search paradigms. However, these effects were rather small, questioning their ecological validity. Thus, our present study aimed to generalize these effects to more naturalistic material (i.e., a paradigm that allows for top-down strategies in highly complex visual s...
As awareness of the phenomenon of aphantasia (= lack of voluntary imagery) has increased in recent years, many psychotherapists ponder its clinical implications. The present study investigates whether aphantasia meets the criteria for mental disorders, i.e. statistical rarity, impairment in activities of daily living, violation of social norms and...
This study highlights psychometric properties and evidence of construct validity on parcel-level for questionnaires on the original and revised reinforcement sensitivity theory. Our data (N = 1,076) suggest good to very good psychometric properties and moderate to excellent internal consistencies. Confirmatory factor analysis (CFA) models suggest a...
Empathy enables human beings to understand and share the internal states of others. Studies show that empathy for pain is higher for in-group compared to out-group members. This might be driven by attitudes and biases towards out-groups. In a between subject design, N = 621 participants filled in questionnaires measuring xenophobia and trait empath...
Postpartum depression (PPD) is a serious health care issue that affects a substantial share of women giving birth. PPD is considered a severe stress response that is likely associated with impaired HPA-axis activity. However, genetic findings regarding HPA-axis effects on PPD are scarce and inconsistent. Inconsistencies may be due to the neglect of...
This paper represents the outcome of a multidisciplinary discussion on what works, what does not, and what can be improved, in ongoing work on biobehavioral taxonomies and their biomarkers. The authors of this paper, representing a wide spectrum of biobehavioral disciplines (clinical, developmental, differential psychology, neurophysiology, endocri...
To examine whether political orientation is reflected in actual behavior, we applied classical paradigms of behavioral economics, namely the Public-Goods- (PGG) and the Trust-Game (TG) which constitute measures of cooperativeness, interpersonal trust and reciprocity respectively in a large German sample of N = 454. Participants intending to vote fo...
Shape-based markers have entered the field of morphometric neuroimaging analysis as a second mainstay alongside conventional volumetric approaches. We aimed to assess the added value of shape description for the analysis of lesional and autoimmune temporal lobe epilepsy (TLE) focusing on hippocampus and amygdala.
We retrospectively investigated MRI...
Background:
With regard to attitudes towards pain, many questionnaires have been developed. Although undoubtedly useful, they were specifically designed for the use in chronic pain and are less suitable for the assessment in the general population. The purpose of the present paper was to develop a measure for the assessment of general attitudes to...
The present opinion paper makes a strong case for a biologically oriented personality theory. A short review on seminal studies applying methods from the neurosciences to unravel the biological underpinnings of personality is given, and findings are critically discussed. It becomes apparent that new methodological advances in the neurosciences prov...
Rationale
Nicotine has been widely studied for its pro-dopaminergic effects. However, at the behavioural level, past investigations have yielded heterogeneous results concerning effects on cognitive, affective, and motor outcomes, possibly linked to individual differences at the level of genetics. A candidate polymorphism is the 40-base-pair variab...
Understanding of emotions and intentions are key processes in social cognition at which serotonin is an important neuromodulator. Its precursor is the essential amino acid tryptophan (TRP). Reduced TRP availability leads to weaker impulse control ability and higher aggression, while TRP supplementation promotes confidence. In a double-blind placebo...
Scene Construction Theory suggests similar neural mechanisms for visual imagery and autobiographical memory, supporting the seeming scientific consensus that a loss of visual imagery affects autobiographical memory. Based on the Dual Coding Theory and the Reverse Hierarchy Model, we also assumed influences of visual imagery on recent visual memory...
Passive consumption of sexually objectifying content on social networking sites (SNS) has been shown to result in lowered body satisfaction and self-esteem, particularly in women. However, deliberate evaluations of sexually objectifying social media content are scarce. Furthermore, associations between self-objectification and active use of SNS in...
Blatantly observable in the U.S. currently, the political chasm grows, representing a prototype of political polarization in most if not all western democratic political systems. Differential political psychology strives to trace back increasingly polarized political convictions to differences on the individual level. Recent evolutionary informed a...
Though meat-consumption is known to be a key factor in environmental damage, veganism and vegetarianism are still perceived to be left-wing-phenomena, ironically not penetrating to those who hold ideologies of conservation. Logical contradictions and historical counter-examples cast doubt on a substantive connection between political orientation an...
Background & Aims
In a placebo controlled study we sought to determine if a four-weeks tryptophan-enriched diet is able to improve age-related depression or social cognitive impairment, depending on polymorphisms located in the promoter region of Solute Carrier Family 6 Member 4 (SLC6A4), also known as serotonin transporter (SERT1) gene.
Methods
9...
Exercise intervention studies in mild cognitive impairment (MCI), a prodromal stage of Alzheimer's disease (AD), have demonstrated inconsistent yet promising results. Addressing the limitations of previous studies, this trial investigated the effects of a 12-month structured exercise program on the progression of MCI. The NeuroExercise study is a m...
The e4 allele of the APOE gene is strongly associated with impaired brain functionality and cognitive decline in humans at older age. It is controversial whether and how the APOE e4 allele is affecting brain activity among young healthy individuals and how such effects may contribute to individual differences in cognitive performance. Signal comple...
The essential amino acid tryptophan (TRP) is discussed as a potential protective factor for physical and mental health. Besides positive effects via the microbiota of the gut on many physiological processes, TRP is the precursor of the neurotransmitter serotonin (5-HT) thereby playing a role for affective disorders. The present study investigated i...
Since the emergence of the SARS-CoV-2 pandemic in December 2019 about 500,000 people died within the first 6 months. The virus itself, as well as the related political decisions, intensified an increasing feeling of fear in billions of people worldwide. However, while some people remained unperturbed, others experienced panic over the current situa...
Recently, it has been observed a relationship between nutrition and social cognition. In this way, several dietary patterns, or even some probiotics, have been reported as social cognition modulators. However,...
The serotonergic (5-HT) system is related to affective and cognitive processes and explains behavioral variability in the normal and psychopathological range. For this reason, the hypothesis was put forward that genetic and epigenetic markers related to 5-HT metabolism predict individual differences in social cognitive functioning. Social cognition...
Oxytocin (OT) regulates social and emotional behaviour. Core symptoms of attention-deficit/hyperactivity disorder (ADHD) include social and emotional dysfunctions potentially associated with lower endogenous OT levels. A dimensional approach was employed to examine relationships between plasma OT levels, ADHD tendencies, and emotionality in a healt...
Gender and personality traits influence risk proneness in the context of financial decisions. However, most studies on this topic have relied on either self-report data or on artificial measures of financial risk-taking behavior. Our study aimed to identify relevant trading behaviors and personal characteristics related to trading success. N = 108...
Exaggerated reactivity to drug‐cues and emotional dysregulations represent key symptoms of early stages of substance use disorders. The diagnostic criteria for (Internet) gaming disorder strongly resemble symptoms for substance‐related addictions. However, previous cross‐sections studies revealed inconsistent results with respect to neural cue reac...
Gray’s theory of personality postulates that fear and anxiety are distinct emotional systems with only the latter being sensitive to anxiolytic drugs. His work was mainly based on animal research, and translational studies validating his theory are scarce. Previous work in humans showed an influence of the benzodiazepine lorazepam on both systems,...
Susceptibility to everyday cognitive failure is often assessed in clinical and vocational settings to estimate the effectiveness of interventions or to predict performance and performance decline in stressful situations. Comparatively little is known about the relationship between cognitive failure susceptibility as quantified by the Cognitive Fail...
A multitude of studies investigating the effects of stress on cognition has produced an inconsistent picture on whether - and under which conditions - stress has advantageous or disadvantageous effects on executive functions (EF).
This review provides a short introduction to the concept of stress and its neurobiology, before discussing the need to...
Exaggerated reactivity to drug-cues and emotional dysregulations represent key symptoms of early stages of substance use disorders. The diagnostic criteria for (Internet) Gaming Disorder strongly resemble symptoms for substance-related addictions. However, previous cross-sections studies revealed inconsistent results with respect to neural cue reac...
Susceptibility to everyday cognitive failure is often assessed in clinical and vocational settings to estimate the effectiveness of interventions or to predict performance and performance decline in stressful situations. Comparatively little is known about the relationship between cognitive failure susceptibility as quantified by the Cognitive Fail...
Background:
The hypothalamus-pituitary-adrenal (HPA) axis, the biological substrate of stress reactivity, and related genetic variations play a crucial role in the initiation and maintenance of drug addiction. On the behavioral level, substance abusers are characterized by impulsivity and the inability to pursue long-term goals. The neural substra...
The ε4 allele of the apolipoprotein (APOE) gene is a widely recognized genetic risk factor for developing Alzheimer’s disease in older age. However, it is controversial whether there is a positive impact of the APOE ε4 allele on human cognitive performance in young adulthood, possibly representing a case of antagonistic pleiotropy. Here we explored...
We organized 10Kin1day, a pop-up scientific event with the goal to bring together neuroimaging groups from around the world to jointly analyze 10,000+ existing MRI connectivity datasets during a 3-day workshop. In this report, we describe the motivation and principles of 10Kin1day, together with a public release of 8,000+ MRI connectome maps of the...
Background: The serotonergic and noradrenergic systems
have a strong impact on several affective disorders and are
key targets for psychopharmacological therapy. With respect
to pathogenesis, there is a growing body of evidence
showing an influence of a promoter repeat polymorphism
(MAOA-uVNTR) altering the expression rate of monoamine
oxidase A. H...
We organized 10Kin1day, a pop-up scientific event with the goal to bring together neuroimaging groups from around the world to jointly analyze 10,000+ existing MRI connectivity datasets during a 3-day workshop. In this report, we describe the motivation and principles of 10Kin1day, together with a public release of 8,000+ MRI connectome maps of the...
A prominent theory of developmental stuttering highlights (dys-)function of the basal ganglia (and in particular the ventral striatum) as a main neural mechanism behind this speech disorder. Although the theory is intriguing, studies on gray matter volume differences in the basal ganglia between people who stutter and control persons have reported...
Response styles (RS) are an important research matter in questionnaire research and have even been interpreted as implicit personality variables aside from explicit personality measurement. To better understand RS and their impact on explicit personality measurement, it is necessary to explore causes of variability in RS, including heritability. Th...
Stress has a critical impact on affective and cognitive processing. Based on rodent data suggesting that endocannabinoid signaling via CB1 receptors serves as an emotional buffer, we hypothesized that a common variant of the gene coding for the CB1 receptor modulates affective processing under stress (CNR1; rs1049353 A vs. G allele). Therefore, 139...
Personality and individual differences originate from the brain. Despite major advances in the affective and cognitive neurosciences, however, it is still not well understood how personality and single personality traits are represented within the brain. Most research on brain-personality correlates has focused either on morphological aspects of th...
Across species, the neuropeptide oxytocin has been associated with affiliative and social approach behavior. It has been suggested to exert its effects by modulating neural circuitry underlying anxiety, affiliative motivation, and social salience. The present study aims to investigate differences in subregional amygdala resting-state connectivity i...