Martin Grosse Holtforth

Martin Grosse Holtforth
Universität Bern | UniBe · Institute of Psychology

PhD

About

346
Publications
195,075
Reads
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5,376
Citations
Additional affiliations
February 2015 - present
Inselspital, Universitätsspital Bern
Position
  • Head of Research
September 2013 - present
University of Bern
Position
  • Professor (Associate)
April 2009 - September 2014
University of Zürich
Position
  • SNSF Professor
Education
December 1996 - December 1999
Universität Bern
Field of study
  • Clinical Psychology (Psychotherapy Research)
June 1992 - September 1993
Duke University
Field of study
  • Psychology
April 1990 - June 1995
Freie Universität Berlin
Field of study
  • Psychology

Publications

Publications (346)
Chapter
Clients may be more or less motivated at the start of psychotherapy, and participation may fluctuate at different stages of the psychotherapy process. This kind of motivation is what people usually associate with the term psychotherapy motivation. Ideally, clients are willing to work hard all through the therapeutic process and invest a lot of effo...
Article
Around 50% of patients with major depression do not respond to standard first-line treatments, such as psychotherapy and pharmacotherapy. At the same time, a subgroup exhibits altered functioning of stress-responsive bodily systems, such as the central locus coeruleus/sympathetic nervous system and the hypothalamic-pituitary-adrenal (HPA) axis. Giv...
Article
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Transdiagnostic psychotherapeutic approaches are increasingly used in neurorehabilitation to address psychological distress. Animal-assistance is thought to increase efficacy. The present study evaluates a psychotherapeutic mindfulness- and self-compassion-based group intervention (MSCBI) with and without animal-assistance for patients with acquire...
Article
Background: Attentional deficits in patients with chronic pain are common and well-studied. Yet, few studies have examined the effects of chronic pain on more complex cognitive abilities that rely on well-functioning attentional systems. With the current study, we aimed to investigate whether the impact of chronic pain on attention affects creativ...
Article
Depression is one of the most prevalent mental disorders, with treatment outcomes generally being unsatisfactory. The identification of outcome predictors could contribute to improving diagnosis, treatment, and outcome. Heart rate variability (HRV), an index of cardiovagal activity, has been proposed as a potential correlate of depression as well a...
Article
Introduction So far, no qualitative content analysis (QCA) has analysed pilots’ experiences and perceptions regarding weaknesses of fatigue risk management (FRM), flight time limitations (FTL), rosters, fatigue-severity, sleep problems, and how they relate to pilots’ mental health and well-being. Objective This research analyses pilots’ described...
Article
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Introduction So far, no qualitative content analysis (QCA) has analysed pilots’ experiences and perceptions regarding weaknesses of fatigue risk management (FRM), flight time limitations (FTL), rosters, fatigue-severity, sleep problems, and how they relate to pilots’ mental health and well-being. Objective This research analyses pilots’ describe...
Article
Full-text available
Objective This study Investigates more dimensions than previous studies simultaneously: pilots’ duty rosters, stress, sleep difficulties, fatigue levels, wellbeing, symptoms of depression, anxiety, and common mental disorders (CMD), and how they are interrelated. Background Several scientific studies have confirmed that fatigue can pose a signif...
Article
Objective: Negative Mood Regulation Expectancies (NMRE) describe the expectancies of an individual regarding his or her ability to regulate or reduce negative mood states by certain cognitive or behavioral strategies. NMRE are closely associated with the actual emotion regulation and potentially buffer the negative psychological and physical healt...
Article
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We aimed at determining differential characteristics of patients treated by a home treatment (HT) team compared to patients treated on hospital wards. Of 412 consecutively admitted patients, 194 (47.1%) were at least partially treated at home, whereas 218 (52.9%) received inpatient treatment only during an episode of acute illness. A multivariate l...
Article
Objectives: Perceived social isolation (PSI), which can be defined as the perception of a lack of quality or quantity in social relationships, has been linked to numerous psychological and physical health problems, as well as physiological stress variables. The cortisol awakening response (CAR), i.e., an increase of cortisol levels after awakening,...
Article
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Although the interrupting effect of chronic pain on voluntary-directed attention is well-documented, research on the impact of chronic pain on involuntary-directed attention remains incomplete. This study aimed to investigate the influence of chronic pain on involuntary as well as voluntary allocation of attention as, respectively, indexed by the P...
Article
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Background The legal and ethical guidelines of psychological professional associations stipulate that informed consent by patients is an essential prerequisite for psychotherapy. Despite this awareness of the importance of informed consent, there is little empirical evidence on what psychotherapists’ attitudes towards informed consent are and how i...
Article
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Objective: This study aimed to investigate the effects of changes in interpersonal cognitions on outcome during cognitive behavioral therapy (CBT) for generalized anxiety disorder (GAD) and how these effects are moderated by patients' interpersonal problems at intake. Method: A sample of 80 adult patients diagnosed with GAD who were undergoing C...
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Background To better understand individual differences between burnout inpatients and improve individually tailored treatments in a psychiatric hospital, cluster analysis based on a number of self-report measures was used to investigate psychosocial characteristics of 96 participants. Method Group membership was analyzed regarding associations wit...
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Teachers report elevated levels of stress and psychosomatic illnesses compared to other professions. Teacher stress has far-reaching consequences on their health outcomes, the student's motivation, and the economy. However, research on teacher stress relies mainly on self-reports, hence, assesses stress on purely subjective perception. Personal or...
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Background Increased long-term glucocorticoid (GC) secretion is an indicator of chronic biological stress, potentially related to poor health and work quality. In the present analysis, we aimed at testing the association between the teacher-student relationship and hair GC concentration in teachers. Methods The concentration of cortisol (hairE) an...
Article
Introduction Recent recommendations for the treatment of chronic pain patients during the COVID-19 pandemic suggest using telemedicine instead of in-person consultations. Knowing whether chronic pain patients are receptive to the use of telemedicine during a pandemic might improve tailored care. Objective The aims of the present study were to asse...
Article
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Objective While previous research focused on pilots’ fatigue, rosters, potential performance-impairment and aviation-safety, this research investigates, how pilots’ work-related and psychosocial stress and rosters can affect their sleep and fatigue. Method A cross-sectional online survey was completed by 192 pilots flying for European operators, 1...
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No se han encontrado instrumentos breves válidos en Argentina para monitorear sintomatología psicológica en psicoterapia. Este trabajo presenta la adaptación argentina del Hopkins Symptoms Checklist (HSCL-11) y estudia sus propiedades psicométricas. Una muestra de 356 participantes completó la adaptación del HSCL-11 junto con medidas de depresión,...
Article
Objective: Entrapment describes a feeling of being stuck in an inescapable aversive situation. This feeling often arises in the context of uncontrollable and/or chronic stress and is associated with various psychopathologies. Due to the nature of their disease, also chronic pain patients might experience their situation as unremitting and inescapa...
Poster
Aim: In depression, one out of four patients has a chronic course of at least two years’ duration. Therefore, patients with chronic depression usually experience a wide range of functional impairments over a long period of time. Considering this long-term character and the symptoms of depression itself, lack of hope for change is an important and c...
Article
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According to consistency theory, insufficient motive satisfaction (motivational incongruence) is associated with psychological distress and mental disorders. High levels of distress and comorbid psychological disorders are common in patients with chronic pain. The aim of the present study was to investigate the role of motivational incongruence in...
Preprint
Full-text available
The present study investigates the effects of negative mood regulation expectancies (NMRE) on symptom severity of depression in 2 cognitive therapies for depression. The sample included the first 146 consecutively recruited patients from a randomized controlled trial. Patients received 22 sessions of either cognitive-behavioral therapy or exposure-...
Article
Objective: There is little evidence-based knowledge of how psychotherapists should handle both sudden gains and more gradual session-by-session changes, either in general or in individuals suffering from generalized anxiety disorder. Methods: Using an ABAB crossed-therapist randomized clinical implementation trial design (N = 80 patients and 20...
Article
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Zusammenfassung. Es gibt zahlreiche neurobiologische, klinische und epidemiologische Belege dafür, dass die Phänomene der Angst- und der Schmerzempfindung eng miteinander interagieren. Beide Systeme gehen mit Stressaktivierungsvorgängen einher, und beide Systeme werden ihrerseits durch Langzeitstress moduliert. Die Koppelung von Schmerz, Angst und...
Article
Objective: This study aims to develop and validate the stigma assessment tool for family member caregivers of patients with mental illness (SAT-FAM). Methods: This study was conducted in three phases: (1) explicate the concept of stigma towards family caregivers of patients with mental illness, (2) develop and iteratively optimise a preliminary...
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Background Mental training intends to support athletes in mastering challenges in sport. The aim of our study was to investigate the differential and shared effects of psychological skills training and mindfulness training on psychological variables relevant to athletic performance (e.g., handling emotions or attention control). We assumed that ea...
Article
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Aim: This study analyzed patient-therapist in-session interpersonal complementarity effects on the therapeutic alliance and depression severity during the initial and working phase of cognitive-behavioral therapy for depression. It also explored if patients’ interpersonal problems moderate those complementarity effects. Methods: We drew on a sample...
Article
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Adjustment disorders (AjD) with depressive symptoms following an acquired brain injury (ABI) is a common phenomenon. Although brain injuries are increasing more and more, research on psychological therapies is comparably scarce. The present study compared, by means of a randomized controlled trial (RCT), a newly developed integrative treatment (Sta...
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The original version of this article unfortunately contains a mistake. The authors regret that the second affiliation of the co-author Martin grosse Holtforth was inadvertently omitted in the manuscript. The details given in this erratum are …
Conference Paper
Ambivalence toward change is an important dimension of patient’s engagement and a relevant process in both poor- and good-outcome cases. In session, it should be successfully managed by the therapist otherwise ambivalence can result in resistance/reactance to therapist’s interventions. Research suggests that when not overcome, these interpersonal t...
Article
Background: Previous research has shown an association between burnout and low emotional competence (EC), defined as the ability to adequately regulate the intensity and expression of emotions. EC might also play a maintaining role in depression. The current paper aimed at studying the effect of improved EC on the course of burnout and depression....
Article
Background and Objectives: This paper examines the discrepancy between implicit and explicit negative self-associations (NSA) after cognitive psychotherapy for depression as a predictor of long-term outcome. Methods: One hundred and twenty patients completed an Implicit-Association Test relating the self with depressive attributes and a self-repor...
Article
Background: The sense of agency is an important aspect of motor control. Impaired sense of agency has been linked to several medical conditions, including schizophrenia and functional neurological disorders. A complex brain network subserves the sense of agency, and the right temporoparietal junction is one of its main nodes. In this paper, we tes...
Article
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Objective: Several studies have reported significant within-patient effects of the therapeutic alliance on outcome. However, it remains uncertain whether there are specific patient groups for whom an improved alliance might be particularly beneficial. The relational nature of the alliance makes patients' interpersonal problems a promising candidat...
Article
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Zusammenfassung. Vernachlässigung, körperliche, psychische oder sexuelle Misshandlung erhöhen das Risiko für Entwicklungsstörungen wie auch das Risiko gesundheitlicher Langzeitfolgen im Erwachsenenalter. Die Prävention von Misshandlungen ist deshalb wichtig. In der Schweiz zeigt sich ein mehrschichtiges Präventionsmodell, dessen Hauptfokus auf der...
Article
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Zusammenfassung. Frühkindliche Stresserfahrungen durch physischen, psychischen und sexuellen Missbrauch sowie emotionale oder physische Vernachlässigung führen oft zu dauerhaften Veränderungen des psychischen Befindens. Klinisch zeigt sich dies u. a. in einer erhöhten Inzidenz für verschiedene psychiatrische Erkrankungen. Diese narrative Überblicks...
Article
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Background Therapeutic alliance has been well established as a robust predictor of face-to-face psychotherapy outcomes. Although initial evidence positioned alliance as a relevant predictor of internet intervention success, some conceptual and methodological concerns were raised regarding the methods and instruments used to measure the alliance in...
Article
Full-text available
Objective: This study aimed to identify differential patient change processes and mechanisms associated with long-term outcome in exposure-based cognitive therapy (EBCT) and cognitive-behavioral therapy (CBT) for depression. Method: We drew on a randomized controlled trial in which 149 patients were randomly assigned to either EBCT or CBT, with...
Article
Objectives: This study aimed to analyze the associations among depressive/anxiety and pain symptoms in patients diagnosed with chronic pain. Methods: Four hundred and fifty-four inpatients who were consecutively admitted in a multimodal 3-weeks treatment in a tertiary psychosomatic university clinic completed 25 items from the Brief Pain Invento...
Article
There is a great need to identify predictors of treatment response, and the analysis of defense mechanisms is a promising approach. Defensive functioning may influence psychotherapy outcome in two ways: First, when it is generally higher or lower for some patients relative to others and second, as it shifts in individual patients over time. The pre...
Article
Even though different psychotherapeutic interventions for depression have shown to be effective, patients suffering from depression vary substantially in their treatment response. The goal of this study was to answer the following research questions: (1) What are the most important predictors determining optimal treatment allocation to cognitive be...
Chapter
Full-text available
The integrative approach described in this chapter represents the authors’ efforts to improve the efficacy of cognitive-behavioral therapy (CBT) via a systematic and theoretically cohesive assimilation of treatment procedures typically associated with other psychotherapy orientations. The primary emphasis is on an integrative therapy for generalize...
Preprint
BACKGROUND The therapeutic alliance has been well established as a robust predictor of face-to-face psychotherapy outcome. Although initial evidence also positioned alliance as a relevant predictor of Internet interventions’ success, some conceptual and methodological concerns were raised regarding the methods and instruments used to measure the al...
Article
Full-text available
Healthcare professionals including psychotherapists are legally and ethically obliged to ensure informed consent for the provided treatments comprising type and duration or potential benefits and possible risks (e.g., side effects) among others. In the present contribution, we argue that as potential benefit, informed consent can foster the patient...
Article
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Die interdisziplinäre multimodale Schmerztherapie (IMST) soll auf der Grundlage eines individuellen Fallverständnisses personalisiert, mechanismenbasiert und zielorientiert erfolgen. Ein praxisnahes Instrument zur Behandlungsplanung für die individualisierte Planung der IMST liegt bislang unseres Wissens nicht vor. Das hier vorgestellte Modell soll...
Article
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Purpose: Chronic pain is a major health concern and its treatment requires physiological as well as psychological interventions. This study investigates the predictive value of health locus of control (HLOC) in pain intensity in chronic pain patients in an inpatient treatment setting. Patients and methods: Data of 225 patients with a chronic pain c...
Article
Objective: This study analyses the psychometric properties of the Working Alliance Inventory adapted for guided Internet interventions (WAI-I). Methods: We drew on the data set from a multicenter trial that examined a guided Internet intervention (deprexis) for patients with mild to moderate depression. Two hundred twenty-three patients complete...
Article
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Purpose: Diagnostic criteria for fibromyalgia have been subject to debate and controversy for many years. The preliminary diagnostic criteria introduced in 2010 and 2011 have been criticized for different reasons, including questionable diagnostic specificity and a lack of an etiopathogenetic foundation. The "ABC indicators" presented in this stud...
Article
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Presenteeism (PRES) includes working while feeling ill and constrained in performance. Compared with absence from work, PRES generates significantly higher cost estimates. Health problems and PRES are related to leadership quality. Hence, research on corporate health management needs to explore why leadership problems (LP) correspond to more frequen...
Poster
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Quality of Leadership and Followers' Preseteeism: A test of a recovery-based process model with cognitive irritation and impaired sleep as mediators
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In many countries, the majority of employees work in SMEs, but research on prevention and interventions with regard to occupational health rarely addresses SMEs. The aim is to give an overview of the evidence on person- and work-related interventions. We conducted a systematic literature search. Fifteen studies on health promotion in SMEs are summa...
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Functional body disorders Abstract. By definition, functional disorders cannot be conceptualized bio-morphologically at the organ level. They originate on the basis of dysregulated control processes and perceptional alterations at a superordinate level of the organism. Under excessive stress, any vegetatively regulated system might develop function...
Article
Background: Defense mechanisms play an important role in the development and maintenance of both health and psychopathology. Research is still in the early stages of investigating the specific relationships among diagnostic groups and defense mechanisms along with their response to different treatment types. Methods: For the present study a tota...
Article
Objective: Previous research has shown that patient's treatment expectations predict outcome in the multimodal therapy for chronic pain. Alexithymia, defined as the difficulty to identify, describe and express one's own feelings, may moderate treatment expectations and thereby effect treatment outcome. Accordingly, the aim of the current study is...
Article
Background: Home treatment has been proposed as an alternative to acute in-patient care for mentally ill patients. However, there is only moderate evidence in support of home treatment. Aims: To test whether and to what degree home treatment services would enable a reduction (substitution) of hospital use. Method: A total of 707 consecutively...