Martin Dawes

Martin Dawes
University of British Columbia - Vancouver | UBC · Department of Family Practice

MD MB.BS FRCGP DRCOG

About

203
Publications
28,874
Reads
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8,891
Citations
Introduction
I worked as a family physician in Oxford starting practice in 1983. In 1992 following the completion of my PhD I helped develop a Masters programme in Evidence Based Health Care. I ran the UK Centre for Evidence-Based Medicine in Oxford and was head of family practice at McGill University before coming to UBC in 2010. I am currently involved in multiple research projects, but primarily about including genomics in primary care, and lifestyle interventions to prevent diabetes.
Additional affiliations
May 2012 - October 2017
University of British Columbia - Vancouver
Position
  • Professor
September 2010 - present
University of British Columbia - Vancouver
Position
  • Head of Family Practice
October 2002 - August 2010
McGill University
Position
  • Head of Family Practice
Education
September 1973 - October 1978
University of London
Field of study
  • Medicine

Publications

Publications (203)
Article
Eczema (atopic eczema) is a common, chronic and recurrent inflammatory skin disease affecting 10‐15% of the population. A limited Canadian study based on a small survey sample reported that the annual cost of eczema is $CAD 1.4 billion dollars, with costs expected to rise further with the introduction of biologic therapies. Its growing global preva...
Article
The use of pharmacogenetic information is becoming mainstream with insurance companies and others starting to pay for widescale implementation of this new technology starting with patients who have anxiety and depression. It has been introduced in response to the unpredictability of medication, the high number of adverse drug events, and lack of dr...
Article
Full-text available
Objectives To study systematic errors in recording blood pressure (BP) as measured by end digit preference (EDP); to determine associations between EDP, uptake of Automated Office BP (AOBP) machines and cardiovascular outcomes. Design Retrospective observational study using routinely collected electronic medical record data from 2006 to 2015 and a...
Article
Introduction: Educational materials improve bone mineral density (BMD) testing rates in high-risk patients, but the effect is unknown in women diagnosed with breast cancer. Methods of delivering educational materials may also affect testing rates. The purposes of this study were to determine the feasibility of the protocol and to pilot-test the ef...
Article
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Objective: A simple, non-invasive sample collection method is key for the integration of pharmacogenetics into clinical practice. The aim of this study was to gain samples for pharmacogenetic testing and evaluate the variation between dry-flocked and sponge-tipped buccal swabs in yield and quality of DNA isolated. Results: Thirty-one participant...
Article
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Objective: To determine the proportion of family medicine patients unwilling to allow their eHealth data to be used for research purposes, and evaluate how patient characteristics and the relevance of research impact that decision. Design: Cross-sectional questionnaire. Setting: Acute care respiratory clinic or an outpatient family medicine clinic...
Article
Background: The efficacy of internet-based interventions to improve hypertension management is not established. We evaluated the therapeutic benefit of e-counseling by adapting best evidence guidelines for behavioral counseling. Methods and results: This multicenter double-blind randomized controlled trial included assessments at baseline, 4 mon...
Article
Background and purpose: Prolonged sedentary time and limited physical activity can result in deleterious effects on health and mobility, especially for older adults with fall-related hip fracture. Therefore, the purpose of this study was to examine the effect of a multidisciplinary clinic on sedentary behavior and physical activity (prespecified s...
Article
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Background: In this paper, our aim was to systematically evaluate published evidence of bone fracture risk associated with tamoxifen and aromatase inhibitors in women aged 65 and under, and diagnosed with nonmetastatic breast cancer. Methods: We comprehensively searched MEDLINE, EMBASE and CINAHL databases from January 1997 through May 2015, and...
Chapter
Pharmacogenomics is one of the cornerstones for implementation of precision medicine. Recent studies indicate that one in four primary care patients is prescribed at least one medication that commonly causes adverse drug reactions due to genetic variability in drug metabolism. Very few studies, however, have focused on implementation of precision m...
Article
Objective: To synthesize evidence on older adults' sedentary behavior and physical activity during rehabilitation and recovery for hip fracture (1) across the care continuum and (2) from clinical interventions. Design: We conducted a systematic review of peer-reviewed publications using CINAHL, Embase, Ovid MEDLINE, PsycINFO, and SportDiscus (la...
Article
Objectives: Physical activity confers many health benefits, but the underlying mechanisms require further exploration. In this pilot randomized controlled trial we tested the association between longitudinal measures of DNA methylation and changes in objective measures including physical activity, weight loss, and C-reactive protein levels in comm...
Article
Introduction: To evaluate the utilization of bone mineral density (BMD) testing for female breast cancer survivors aged 65+ surviving ≥ 3 years in British Columbia, Canada. Methods: A retrospecitve population-based data linkage study. Trends in proportion of survivors with ≥ 1 BMD test for each calendar year from 1995 to 2008 were evaluated with...
Article
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Objective: To describe the techniques currently used by family physicians in Canada to measure blood pressure (BP) for screening for, diagnosing, and treating hypertension. Design: A Web-based cross-sectional survey distributed by e-mail. Setting: Stratified random sample of family physicians in Canada. Participants: Family physician members...
Article
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PurposeThe study aims to better understand Pap test utilization for cancer survivors diagnosed before age 25 in British Columbia (BC), Canada. MethodsA population-based cross-sectional data linkage study that included 1285 5-year female cancer survivors diagnosed with cancer before age 25 and 12,185 randomly selected and birth-year-matched BC femal...
Article
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Objective: In Canada, primary care reform has encouraged innovations, including nurse practitioners (NPs) and group medical visits (GMVs). NP-led GMVs provide an opportunity to examine barriers and enablers to implementing this innovation in primary care. Design: An instrumental case study design (n=3): two cases where NPs were using GMVs and on...
Article
In Canada, increasing numbers of people with chronic conditions have prompted calls for innovative approaches to delivering primary care. These approaches may include group medical visits (GMVs) and the introduction of nurse practitioners (NPs). We examined why NPs in the province of British Columbia were not using GMVs. This case study is part of...
Article
Since the publication of the 2012 guidelines new literature has emerged to inform decision making. The 2016 guidelines primary panel selected a number of clinically relevant questions and has produced updated recommendations, based on important new findings. In subjects with clinical atherosclerosis, abdominal aortic aneurysm, most subjects with di...
Article
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Background: Inappropriate prescribing increases patient illness and death owing to adverse drug events. The inclusion of genetic information into primary care medication practices is one solution. Our aim was to assess the ability to obtain and genotype saliva samples and to determine the levels of use of a decision support tool that creates medica...
Article
Objective: To highlight the 2015 Canadian Hypertension Education Program (CHEP) recommendations for the diagnosis and assessment of hypertension. Quality of evidence: A systematic search was performed current to August 2014 by a Cochrane Collaboration librarian using the MEDLINE and PubMed databases. The search results were critically appraised by...
Article
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Type 2 diabetes mellitus (T2DM) affects more than 1.1 million Canadians aged ≥65 years. Group Medical Visits are an emerging health service delivery method. Recent systematic reviews show that they can significantly reduce glycated haemoglobin (HbA1c) levels, but Group Visits have not been evaluated within primary care. We intend to determine the c...
Article
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The International Cancer Benchmarking Partnership (ICBP) is a collaboration between 6 countries and 12 jurisdictions with similar primary care-led health services. This study investigates primary care physician (PCP) behaviour and systems that may contribute to the timeliness of investigating for cancer and subsequently, international survival diff...
Article
Despite progress in automated blood pressure measurement (BPM) technology, there is limited research linking hard outcomes to automated office BPM (OBPM) treatment targets and thresholds. Equivalences for automated BPM devices have been estimated from approximations of standardized manual measurements of 140/90 mmHg. Until outcome-driven targets an...
Article
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Most epidemiologic reports on hypertension in Canada are based on data from surveys or on administrative data. We report on the prevalence and management of hypertension based on data from the Canadian Primary Care Sentinel Surveillance Network (CPCSSN), which consists of validated, national, point-of-care data from primary care practices. We inclu...
Article
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Maintaining physical activity is an important goal with positive health benefits, yet many people spend most of their day sitting. Our Everyday Activity Supports You (EASY) model aims to encourage movement through daily activities and utilitarian walking. The primary objective of this phase was to test study feasibility (recruitment and retention r...
Article
The scale and rapid expansion of urbanization resulting from socio-economic transformation in China at the beginning of the 21st century has accelerated rural-urban migration. Public health concerns from this increasing internal population mobility are now receiving attention from researchers. The health problems from internal migration pose partic...
Article
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Despite the increased risk of cardiovascular disease and type 2 diabetes associated with excess bodyweight, development of a clinically meaningful metric for health professionals remains a challenge. We estimated the years of life lost and the life-years lost from diabetes and cardiovascular disease associated with excess bodyweight. We developed a...
Article
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To determine the feasibility of implementing a large-scale primary care-based diabetes prevention trial.MethodsA feasibility cluster randomized controlled trial was conducted in British Columbia, Canada, amongst adults with prediabetes using the Facilitated Lifestyle Intervention Prescription (FLIP) vs. usual care. FLIP included lifestyle advice, a...
Article
Open-source software (OSS) has achieved widespread adoption in many domains such as server operating systems, enterprise tools, and databases. We review the status of open-source in healthcare and discuss the potential of open-source to resolve some of the challenges surrounding the wide adoption of Health IT in North America. Specifically, we addr...
Article
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Objective: To assess the feasibility and acceptability of administering the validated Case-finding Health Assessment Tool (CHAT) in Canadian family practice waiting rooms to identify risk factors for depression, anxiety, anger control,smoking, drinking, other drug use, gambling, exposure to abuse, and physical inactivity. Design: Cross-sectional...
Article
Background Despite the increased risk of cardiovascular disease and type 2 diabetes associated with excess bodyweight, development of a clinically meaningful metric for health professionals remains a challenge. We estimated the years of life lost and the life-years lost from diabetes and cardiovascular disease associated with excess bodyweight.
Article
Full-text available
AimAdverse drug events lead to increased morbidity, mortality and health care costs. Pharmacogenetic testing that guides drug prescribing has the potential to reduced adverse drug events and increase drug effectiveness. Our aim was to quantify the clinical effectiveness of genotype-guided prescribing.Methods Three electronic databases were searched...
Article
Primary care is recognized worldwide as a key component for improving health outcomes in the population. At the same time, healthcare systems are rapidly changing with increasing expectations from technological advances. Genomics is a major driver in changing how medicine is being practiced; however, the importance for primary care has been under-a...
Article
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Survival rates following a diagnosis of cancer vary between countries. The International Cancer Benchmarking Partnership (ICBP), a collaboration between six countries with primary care led health services, was set up in 2009 to investigate the causes of these differences. Module 3 of this collaboration hypothesised that an association exists betwee...
Conference Paper
Full-text available
Over the two days of the workshop, it became clear that there is much opportunity in the realm of primary care genomics and that significant research efforts have already been invested in key aspects of the translational process. The biggest question at this point seems to be exactly which genomic tests are most “ready for primetime”, with pharmaco...
Article
To provide FPs with detailed knowledge of automated office blood pressure (AOBP) measurement, its potential role in primary care, and its proper use in the diagnosis and management of hypertension. Comprehensive monitoring and collection of scientific articles on AOBP by the authors since its introduction. Automated office blood pressure measuremen...
Article
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Background: Group medical visits, whereby health care professionals meet with groups of patients who have the same disease, have been introduced in primary care as a way to meet the increasing demand for health care delivery to patients with chronic diseases. We performed a systematic review and meta-analysis of the evidence on the effectiveness o...
Article
Full-text available
Web-based lifestyle counselling designed to improve adherence to self-management behaviours for diet, exercise and medication has been shown to reduce blood pressure (BP). However, the long-term clinical outcome of these interventions is not established. Our aim was to establish whether an e-counselling program is independently associated with impr...
Article
SUMMARY Case report data and a matched case-control study were used to investigate the epidemiological characteristics of hand, foot and mouth disease (HFMD) in children in Shenzhen, China between 2008 and 2011. Multivariate analyses were used to evaluate factors associated with severity of infection. Laboratory tests were performed to determine ae...
Article
Case report data and a matched case-control study were used to investigate the epidemiological characteristics of hand, foot and mouth disease (HFMD) among children in Shenzhen China between 2008 and 2011. Multivariate analyses were used to evaluate factors associated with severity of infection. Laboratory tests were performed to decide etiological...
Article
Full-text available
Background Socioeconomic transformation in China at the beginning of the twenty-first century has led to rapid urbanization and accelerated rural-urban migration. As a result, the concerns about public health problems triggered by increasing internal population mobility have been more widely studied in recent years.Sources of dataPublished data in...
Article
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The Canadian Hypertension Education Program reviews the hypertension literature annually and provides detailed recommendations regarding hypertension diagnosis, assessment, prevention, and treatment. This report provides the updated evidence-based recommendations for 2015. This year, 4 new recommendations were added and 2 existing recommendations w...
Article
In the context of organizational transitions in health care institutions, the decisions taken by leaders and clinicians are informed by multiple sources and by a multitude of actors at all levels of the organization. A study was conducted in the context of a major organizational transition at the McGill University Health Centre in Montreal, Quebec,...
Article
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Background: International guidelines for the management of nonvariceal upper gastrointestinal bleeding have not been widely adopted in clinical practice. We sought to determine whether a national, multifaceted intervention could improve adherence to guidelines, especially for patients at high risk of nonvariceal upper gastrointestinal bleeding. M...
Article
Health information technology represents a promising avenue to improve health care delivery. How can we use lessons learnt from existing health information technologies in primary care to inform the optimal design of newer developments such as personal health records? The results of systematic literature reviews about the impact of different inform...
Article
Objectives: To determine the prevalence of masked hypertension [normal office blood pressure (BP) with high awake ambulatory BP] using automated office BP (AOBP) or conventional manual office BP (MOBP) measurement in routine clinical practice. Methods: The prevalence of masked hypertension was evaluated on three consecutive visits during a media...
Article
We updated the evidence-based recommendations for the diagnosis, assessment, prevention, and treatment of hypertension in adults for 2012. The new recommendations are: (1) use of home blood pressure monitoring to confirm a diagnosis of white coat syndrome; (2) mineralocorticoid receptor antagonists may be used in selected patients with hypertension...
Article
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Background: While several studies of smoking behaviors in rural-to-urban Chinese migrants exist, none to our knowledge have focused on factory workers, estimated to represent between 10% and 20% of China's total rural-to-urban migratory population. This paper assesses factors associated with smoking behavior among rural-to-urban migrant factory wo...
Conference Paper
Full-text available
Estimating query performance is the task of predicting the quality of results returned by a search engine in response to a query. In this paper, we focus on pre-retrieval prediction methods for the medical domain. We propose a novel predictor that exploits a thesaurus to ascertain how difficult queries are. In our experiments, we show that our pred...
Article
Full-text available
ABSTRACT: High blood pressure is a major, modifiable risk factor for heart attack, stroke, and renal failure. One in five Canadians have high blood pressure. Blood pressure measure- ment is one of the most commonly performed medical tests. Accurate BP measurement is the foundation of optimal diagnosis and treatment of hypertension. Although the las...
Article
Effective strategies to identify office-induced hypertension in routine clinical practice are required to improve diagnosis and management of hypertension. To compare the quality and accuracy of automated office blood pressure (AOBP) measurement using the BpTRU device with manual office blood pressure (MOBP) in routine clinical practice using awake...