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Publications
Publications (36)
A subset of patients with post-COVID-19 condition (PCC) fulfill the clinical criteria of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). To establish the diagnosis of ME/CFS for clinical and research purposes, comprehensive scores have to be evaluated. We developed the Munich Berlin Symptom Questionnaires (MBSQs) and supplementary scor...
Hintergrund: Zur besseren Versorgung von an Post-COVID erkrankten Kindern und Jugendlichen wurde in Bayern ein Versorgungsnetzwerk (Post-COVID Kids Bavaria, „PoCo“) aufgebaut. Ziel dieser Studie ist die Beschreibung des Erkrankungserlebens bei Kindern und Jugendlichen mit Post-COVID, ihrer Erfahrungen und Zufriedenheit mit der Versorgung im PoCo-Ne...
Purpose: A subset of patients with post-COVID-19 condition (PCC) fulfill the clinical criteria of myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS). To establish the diagnosis of ME/CFS for clinical and research purposes, comprehensive scores have to be evaluated.
Methods: We developed the Munich Berlin Symptom Questionnaires (MBSQs) an...
[This corrects the article DOI: 10.2196/41010.].
BACKGROUND
Some children and adolescents suffer from late effects of a SARS-CoV-2 infection despite frequently mild courses of the disease. Nevertheless, extensive care for Post-COVID in children and young people is not available yet. A comprehensive care network (“PoCo”) for children and adolescents with Post-COVID has been setup as a model projec...
Background:
Some children and adolescents suffer from late effects of a SARS-CoV-2 infection despite frequently mild courses of the disease. Nevertheless, extensive care for Post-COVID in children and young people is not available yet. A comprehensive care network ("PoCo") for children and adolescents with Post-COVID has been setup as a model proj...
Zusammenfassung
Das vorliegende Konsensuspapier bietet in Ergänzung zur AWMF-S1-Leitlinie eine Übersicht über die verschiedenen klinischen Aspekte von Long COVID im Kindes- und Jugendalter. Es wurde von Vertreter:innen aus 19 Fachgesellschaften des DGKJ-Konvents und kooperierenden Fachgesellschaften erstellt und bietet Expertenempfehlungen für die...
Background:
This study aimed to investigate the morbidity profile and the sociodemographic characteristics of unaccompanied refugee minors (URM) arriving in the region of Bavaria, Germany, between October 2014 and February 2016.
Methods:
The retrospective cross sectional study included 154 unaccompanied refugee minors between 10 and 18 years of...
Background:
Vaccines based on mRNA coding for antigens have been shown to be safe and immunogenic in preclinical models. We aimed to report results of the first-in-human proof-of-concept clinical trial in healthy adults of a prophylactic mRNA-based vaccine encoding rabies virus glycoprotein (CV7201).
Methods:
We did an open-label, uncontrolled,...
HintergrundDeutschland verzeichnete 2015 einen Zuwachs des Flüchtlingsstroms auf etwa 1 Mio. Menschen. Die medizinische Versorgung dieser Patientengruppe birgt einige Besonderheiten, die sich von der medizinischen Versorgung der einheimischen Bevölkerung grundlegend unterscheiden. Katastrophale hygienische Bedingungen während der Flucht sowie Mange...
After collapsing in Munich, Germany, a 16-year-old male Somalian refugee was brought to a local hospital with severe headache and abdominal pain. His vital signs were notable for a temperature of 41°C, a heart rate of 105 beats per minute, blood pressure of 95/50 mm Hg, and an oxygen saturation of 98% while he was breathing ambient air. On examinat...
Die zunehmende Reiseaktivität der Deutschen und v. a. der stark gewachsene Zustrom von Migranten und Flüchtlingen aus Malariaendemiegebieten haben in den letzten Jahren zu einem Anstieg der Malariafallzahlen in Deutschland geführt. Die unspezifischen Symptome der Erkrankung können immer wieder zu Fehldiagnosen führen, die in lebensbedrohlichen Verl...
The aim of this controlled cross-sectional study was to assess the clinical validity of elevated values of three clinically relevant transferase enzymes (aspartate transaminase [AST], alanine transaminase [ALT], and gamma-glutamyl transferase [GGT]) induced by imported infectious diseases (IDs) seen among patients consulting the Division of Infecti...
Background:
Conventional rabies pre-exposure prophylaxis (PrEP) and Japanese encephalitis (JE) primary series vaccination regimens each require up to 4 weeks to complete and, thus, may not be feasible for individuals who need these immunizations on short notice. This Phase 3b, randomized, controlled, observer-blind study evaluated the immunogenici...
The aim of this study was to assess the spectrum of imported infectious diseases (IDs) among patients consulting the University of Munich, Germany, between 1999 and 2014 after being in the sub-/tropics. The analysis investigated complete data sets of 16,817 diseased German travelers (2,318 business travelers, 4,029 all-inclusive travelers, and 10,4...
Long-haul journeys are still very popular. Besides holiday trips, a growing number of families is visiting foreign countries for the reason of career development. During travel the families can acquire illnesses which are not regularly considered in the differential diagnosis in the home country. This can lead to life threatening events, for exampl...
Background: In 2014 the number of refugees and asylum seekers in Germany rose steeply. Therefore, the provision of sufficient medical care for this special group of people became a major topic. Up to now, data on the spectrum of illnesses in this group in Germany is scarce. Patients and Methods: Anonymized data of 548 ill refugees and asylum seeker...
For individuals traveling at short notice to rabies and Japanese encephalitis (JE) endemic countries, concomitant administration of travel vaccines within a short period is often required.
The aim of this study was to determine whether an accelerated (one-week: Days 1-8) pre-exposure rabies (Rabipur(®), Novartis Vaccines) vaccination regimen admini...
This phase 3b randomized, open-label study evaluated the immunogenicity and safety of coadministration of a hepatitis A and/or B vaccine with a quadrivalent oligosaccharide meningococcal CRM197 -conjugate vaccine (MenACWY-CRM), in the context of an accelerated hepatitis A and/or B immunization schedule.
A total of 252 healthy adult subjects were ra...
Background:
Compact and short pre-travel immunization schedules, which include several vaccinations in a single visit, are desirable for many travelers. However, concomitant vaccination could potentially compromise immunogenicity and/or safety of the individual vaccines and, therefore, possible vaccine interferences should be carefully assessed. T...
Background
Potential interactions between vaccines may compromise the immunogenicity and/or safety of individual vaccines so must be assessed before concomitant administration is recommended. In this study, the immunogenicity and safety of travel vaccines against Japanese encephalitis (JEV) and rabies (PCECV) administered together with or without a...
Long-haul journeys are still very popular. Besides holiday trips, a growing number of families is visiting foreign countries for the reason of career development. During travel the families can acquire illnesses which are not regularly considered in the differential diagnosis in the home country. This can lead to life threatening events, for exampl...
Vaccinations are a prominent part of health preparations before international travel. They can avoid or significantly reduce the risk of numerous infectious diseases. Until recently, vaccination against yellow fever was the only obligatory vaccination. However, according to updated international health regulations, other vaccinations and prophylact...
Als Tropen bezeichnet man die Regionen zwischen den Wendekreisen (trópos: griechisch für Wendung, 23°26′16″ nördlicher und südlicher Breite), als Subtropen die angrenzenden Gebiete bis zu 35° nördlicher bzw. südlicher Breite, in denen die jährliche Mitteltemperatur über 20°C beträgt. Die Tropenmedizin im klassischen Sinn befasst sich mit den Gesund...
Fernreisen in tropische Lander sind weiterhin sehr beliebt. Neben der Erweiterung des Erfahrungshorizonts besteht immer die Moglichkeit, wahrend der Reise Erkrankungen zu erwerben. Bei Reiseruckkehrern treten hauptsachlich Durchfall- und Hauterkrankungen, aber auch fieberhafte Allgemeinerkrankungen bis hin zu schwerwiegenden Infektionen wie Malaria...
International Reisende haben ein Risiko für eine Vielzahl von Erkrankungen, die in Deutschland kaum oder gar nicht auftreten. Durch ein verändertes Verhalten während der Reise besteht die Gefahr des Erwerbs von Infektionserkrankungen oder der Einnahme von toxischen Substanzen. Dabei kann es zu schweren Leberschädigungen kommen. Erkrankungen wie Mal...
A central aspect of travel medicine is to counsel and to vaccinate the traveller to prevent hazardous infectious diseases. The growing number of international travellers and the expanding risk areas of infectious diseases formerly specific for tropical countries e. g. Dengue or Chikungunya, which may be a possible result of climate change, increase...
