Marte Theie Gustavsen

Marte Theie Gustavsen
Oslo University Hospital · Department of Transplantation Medicine

Master of Pharmacy PhD

About

8
Publications
486
Reads
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111
Citations
Citations since 2016
8 Research Items
111 Citations
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2016201720182019202020212022051015202530
2016201720182019202020212022051015202530

Publications

Publications (8)
Article
Background: Prednisolone (PL) is a standard component of most immunosuppressive protocols following solid organ transplantation (Tx). Adverse effects are frequent and well-known. The aim of this study was to characterize the pharmacokinetics of PL and prednisone (PN), including cortisol (CL) and cortisone (CN) profiles, after PL treatment in renal...
Article
Full-text available
Therapeutic drug monitoring (TDM) is mandatory for the immunosuppressive drug tacrolimus (Tac). For clinical applicability, TDM is performed using morning trough concentrations. With recent developments making tacrolimus concentration determination possible in capillary microsamples and Bayesian estimator predicted area under the concentration curv...
Article
Background: Therapeutic drug monitoring (TDM) of tacrolimus (Tac) is mandatory in renal transplant recipients (RTxR). Area under the concentration versus time curve (AUC) is the preferred measure for Tac exposure; however, for practical purposes, most centers use trough concentrations as a clinical surrogate. Limited sampling strategies (LSS) in c...
Article
Background: Therapeutic drug monitoring is standard practice for the immunosuppressant tacrolimus (Tac). Venous blood sampling at outpatient clinics is time-consuming and impractical with regard to obtaining trough concentrations on clinical visit days. Home-based blood sampling may be patient friendly and pave the way for limited sampling strateg...
Article
Background: Patients with high tacrolimus clearance eliminate more drug within a dose interval compared to those with low clearance. Delays in dosing time will result in transient periods of lower concentrations in high versus low clearance patients. Transient subtherapeutic tacrolimus concentrations may induce acute rejection episodes. Methods:...

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