Marta Lancione

Marta Lancione
IRCCS Stella Maris, Pisa · FiRMLAB

PhD in Neuroscience | BSc/MSc in Physics

About

8
Publications
535
Reads
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62
Citations
Citations since 2017
8 Research Items
62 Citations
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201720182019202020212022202305101520
Introduction
Additional affiliations
July 2022 - present
IMAGO7 Foundation
Position
  • Postdoctoral researcher

Publications

Publications (8)
Article
Full-text available
Quantitative Susceptibility Mapping (QSM) is an MRI-based technique allowing the non-invasive quantification of iron content and myelination in the brain. The RIN – Neuroimaging Network established an optimized and harmonized protocol for QSM across ten sites with 3T MRI systems from three different vendors to enable multicentric studies. The asses...
Article
Full-text available
Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal stage of α-synucleinopathies, such as Parkinson's disease (PD), which are characterized by the loss of dopaminergic neurons in substantia nigra, associated with abnormal iron load. The assessment of presymptomatic biomarkers predicting the onset of neurodegenerative d...
Article
Full-text available
The non-invasive quantification of iron stores via Quantitative Susceptibility Mapping (QSM) could play an important role in the diagnosis and the differential diagnosis of atypical Parkinsonisms. However, the susceptibility (χ) values measured via QSM depend on echo time (TE). This effect relates to the microstructural organization within the voxe...
Article
Full-text available
Functional Quantitative Susceptibility Mapping (fQSM) allows for the quantitative measurement of time-varying magnetic susceptibility across cortical and subcortical brain structures with a potentially higher spatial specificity than conventional fMRI. While the usefulness of fQSM with General Linear Model and “On/Off” paradigms has been assessed,...
Article
Quantitative Susceptibility Mapping (QSM) provides a way of measuring iron concentration and myelination non-invasively and has the potential of becoming a tool of paramount importance in the study of a host of different pathologies. However, several experimental factors and the physical properties of magnetic susceptibility (χ) can impair the reli...
Article
Functional Quantitative Susceptibility Mapping (fQSM) is a recently established method that, based on the same acquisition technique as conventional functional Magnetic Resonance Imaging, has two very appealing features: it is quantitative and it is considerably less affected by non-local effects than the Blood Oxygenation Level-Dependent (BOLD) si...
Article
The aim of this work was to assess the impact of tissue structural orientation on quantitative susceptibility mapping (QSM) reliability, and to provide a criterion to identify voxels in which measures of magnetic susceptibility (χ) are most affected by spatial orientation effects. Four healthy volunteers underwent 7-T magnetic resonance imaging (MR...

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