Marlise dos Santos

• Consultant at INNOVASPACE SPACE WITHOU BORDERS

Introduction: Exposure of the human body to the aerospace environment is capable of producing various physiological changes, which contributes to greater susceptibility of acquiring viral and/or bacterial infections. Objective: To review studies on the use of antimicrobials in space to provide up-to-date information on the treatment of infectious d...

italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Goal : Lessons learned from decades of human spaceflight have helped advance the delivery of healthcare in rural and remote areas of the globe. Inclusion of the public in spaceflights is not yet accompanied by technology capable of monitoring their phy...

Introduction: Skateboarding is one of the most popular cultures in Brazil, with more than 8.5 million skateboarders. Nowadays, the discipline of street skating has gained recognition among other more classical sports and awaits its debut at the Tokyo 2020 Summer Olympic Games. This study aimed to explore the state-of-the-art for inertial measuremen...

INTRODUCTION: Plant germination and growth are influenced by innumerous environmental factors, such as the level of gravity and type of radiation. Several plants have nutritive and medicinal value, making the importance of their cultivation and consumption during space missions unquestionable. Studies demonstrate that simulated hypergravity, throug...

Running and walking stimulate and maintain the functioning of the musculoskeletal and cardiopulmonary systems, which are responsible for body posture, movement, strength and coordination on Earth and during space missions. This study aimed to develop a low-cost Gait System in Hypogravity Simulation (GSHS) for the study of human physiology. The deve...

Diante do aumento do número de passageiros transportados por via aérea e consequente aumento do número de ocorrências médicas a bordo, buscou-se estabelecer o perfil epidemiológico dos passageiros da Azul Linhas Aéreas Brasileiras e comparar com estudos conduzidos em empresas aéreas estrangeiras. Paralelamente avaliou-se a efetividade do uso de um...

The Effects of Hypergravity and Radiation Exposure on Plants and their Terrestrial and Space Applications Marlise A dos Santos, Ph.D.1, Beatriz A de Souza1, Natalia Guimarães1, Felipe C Escobal1, Patrícia B. Lazzarotto1, Philippe A Souvestre2, Thais Russomano3. 1Microgravity Centre- PUCRS, Av Ipiranga, 6681, Partenon - Porto Alegre, 90619-900 / RS...

The aim of this study was to evaluate the growth responses of various Eucalyptus and Corymbia species subjected to different intensities of simulated hypergravity relative to the control. A centrifuge was used to simulate hypergravity. It was developed and built at the Centro de Microgravidade of the Pontifícia Universidade Católica do Rio Grande d...

The aim of this study was to evaluate the growth responses of various Eucalyptus and Corymbia species subjected to different intensities of simulated hypergravity relative to the control. A centrifuge was used to simulate hypergravity. It was developed and built at the Centro de Microgravidade of the Pontifícia Universidade Católica do Rio Grande d...

This two-volume handbook, directed at medical professionals who are involved in developing the space industry or are academicians (such as at Harvard, Stanford, and MIT) doing research in this area, covers current pharmaceutical knowledge about the difference in medication efficacy in space versus on Earth and includes trial results and best practi...

Introduction Skateboarding is one of the most popular cultures in Brazil, with more than 8.5 million skateboarders. Nowadays, the discipline of street skating has gained recognition among other more classical sports and awaits its debut at the Tokyo 2020 Summer Olympic Games. This study aimed to explore the state-of-the-art for inertial measurement...

Com os avanços tecnológicos nas ferramentas de informação e comunicação, a assistência em saúde tem sido aperfeiçoada, o que aprimorou o atendimento médico e o acesso a serviços de saúde. A Telessaúde é facilmente aplicável e está presente tanto em chamadas telefônicas de emergência quanto na realização de exames médicos à distância. Nesse cenário,...

Telemedicine is a resource that contributes to improving the quality of medical care, reducing the time between diagnosis and therapy, and helping extend specialised and quality medical services to remote or poor locations. Teledermatology and Telecardiology encompass the application of telecommunication and computer technologies in dermatological...

RESUMO Automedicação é o uso de medicamento sem prescrição, orientação ou acompanhamento do médico ou dentista, pode ocasionar danos à saúde, e sua prática com o passar dos anos vem crescendo no Brasil e em outros países. Fatores econômicos, políticos e culturais tem contribuído para o crescimento e a difusão da automedicação, tornando-a um problem...

Finding adequate carriers for protein and peptide delivery has become an urgent need, owing to the growing number of macromolecules identified as having therapeutic potential. Nanoparticles have emerged in the field as very promising vehicles and much work has been directed to testing the capacity of different materials to compose the matrix of the...

Abstract Purpose: This project includes an analysis of nanoemulsions in microgravity simulation. Based on the understanding of these simulations, we can design and produce nanoemulsion drugs stable enough to go on the mission to space. Methods: Oil in water nanoemulsions were formulated using 30% oil and 70% water phase. A total of five nanoemulsio...

Hypergravity is able to stimulate at a cellular level both the lignin formation and the peroxidase enzyme action in plants. Centrifuges have proven to be one of the most important tools for researchers for simulating such conditions. This paper presents a new design for a centrifuge simulating hypergravity used for plant experiments. It represents...

To identify and describe actual or potential medication errors related to drug information inquiries made by staff members of a teaching hospital to a Drug Information Centre from January 2012 to December 2013. Data were collected from the records of inquiries made by health care professionals to the Drug Information Centre throughout this period....

A process of germinate and grow plants under hypergravity, which is created by a small centrifuge

Purpose Reducing inequity in accessing healthcare among rural and remote populations remains a problem. Internationally, eHealth is now touted as a potential solution, with a range of diverse approaches and impacts. Yet, the equity gains of implementing eHealth are often not realized due to a lack of effective strategies for citizen participation....

Telepharmacy, one of the areas of Telemedicine, allows health teams and patients to have virtual contact with remote pharmacists, improving healthcare quality in rural and remote locations. The Telemedicine Laboratory of the Microgravity Centre/FENG at PUCRS University coordinates eHealth projects aimed at making available specialized assistance to...

Although it has been suggested that microgravity might affect drug absorption in vivo, drug permeability across epithelial barriers has not yet been investigated in vitro during modelled microgravity. Therefore, a cell culture/diffusion chamber was designed specifically to accommodate epithelial cell layers in a 3D-clinostat and allow epithelial pe...

Exposure to microgravity may produce changes in the performance of the immunological system at the cellular level and in the major physiological systems of the body. Weightlessness suppresses the lymphocytic functions involved in the immunity process, such as cell locomotion and expression of antigen. The present study was designed to investigate w...

The plant drug “taiuia” is described in the Brazilian Pharmacopeia as the roots of Cayaponia tayuya (Vell.) Cogn. Popularly, however, other species of Cucurbitaceae are also named “taiuia”. Here, we report that products labeled as C. tayuya, in the Brazilian market, may be Wilbrandia ebracteata (Cogn.) Cogn. The major C-glycosylflavones identified...

The recent engagement of Brazil in the construction and utilization of the International Space Station has motivated several Brazilian research institutions and universities to establish study centers related to Space Sciences. The Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS) is no exception. The University initiated in 1993 the fi...

There is currently no effective method of measuring arterial blood gas tensions in austere environments such as in space or at high altitude. An alternative to direct arterial measurement is the sampling of arterialized earlobe blood, an accurate technique that has been in use in clinical medicine and physiology for more than 50 yr. We, therefore,...

The vestibular system, along with the eyes and proprioceptors, is responsible for the maintenance of balance. Two very common causes of accidents and incidents during flights and space missions are spatial disorientation and motion sickness. Since its invention by the physiologist Robert Barany, rotatory chairs have been widely used to train pilots...

Introduction: The intra-ocular pressure (IOP) increases during microgravity exposure and with increasing angles of head-down tilt (HDT). Studies conducted during the first 15 min of German Spacelab D1 and D2 missions showed a 92% to 114% rise in the IOP compared to the baseline values. The central venous pressure, however, decreases immediately aft...

Essential oils, which were obtained from the inflorescences of eight samples of Achyrocline satureioides (Lam.) DC collected from different areas of Brazil, were analyzed by GC and GC/MS. Thirty-two compounds representing 86–98% of the oils were identified. In each of the oils, a-pinene was always the most abundant (41–78%); the distribution of the...