Marlies Den Hollander

Marlies Den Hollander
Adelante Zorggroep

PhD

About

28
Publications
6,598
Reads
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524
Citations
Introduction
Research interests: exposure in vivo, pain-related fear, inhibitory learning, chronic pain, pain after breast cancer.
Additional affiliations
January 2010 - present
Maastricht University

Publications

Publications (28)
Article
Objective: To investigate whether early changes in fear of movement (kinesiophobia), self-efficacy, and catastrophising were mediators of the relationship between allocation to the pre-habilition intervention and later changes in health outcomes. Methods: The original prehabilitation trial (PREPARE, ISRCTN17115599) recruited 118 participants awa...
Article
Full-text available
Exposure in vivo (EXP) is an effective treatment to reduce pain-related fear and disability in chronic pain populations. Yet, it remains unclear how reductions in fear and pain relate to each other. This single-case experimental design study attempted to identify patterns in the individual responses to EXP and to unravel temporal trajectories of fe...
Article
: Pain-related fear (PRF) can be a significant factor contributing to the development and maintenance of pain-related disability in individuals with persistent pain. One treatment approach to target PRF and related avoidance behavior is exposure in vivo (EXP). EXP has a long history in the field of anxiety, a field that is constantly evolving. Thi...
Article
Full-text available
Exposure in vivo is a theory-driven and widely used treatment to tackle functional disability in people with chronic primary pain. Exposure is quite effective; yet, in line with exposure outcomes for anxiety disorders, a number of patients may not profit from it, or relapse. In this focus article, we critically reflect on the current exposure proto...
Article
Objective: Public health legislation during the CO-VID-19 pandemic has resulted in forced transitioning to the use of remote care in order to continue the provision of pain rehabilitation worldwide. The objective of this study was to gain insight into clinicians' initial experiences with the provision of interdisciplinary pain rehabilitation via v...
Article
Exposure in vivo has been found successful in reducing pain-related fear, disability, and experienced pain in chronic pain patients. Despite the success of exposure treatment, experimental studies show that extinction learning is fragile, raising doubts whether extinction of pain-related fear generalizes to new threatening activities after treatmen...
Article
Full-text available
Objective: Painful diabetic neuropathy is associated with low quality of life, depression and anxiety. Patients are limited in their performance of activities of daily living due to fears related to their condition. Treatment modalities are needed to help patients cope with their pain and pain-related disability. Exposure in vivo is an effective tr...
Chapter
Wanneer patiënten na een succesvol doorlopen revalidatie opnieuw beperkingen ervaren en een verminderde participatie, dan spreken we van een terugval. Voor de patiënt lijkt een toename van pijn vaak een trigger, maar als behandelaar vraagt men zich af welke verandering heeft geleid tot een terugval in gedrag zoals vóór de revalidatie. Al tijdens de...
Article
Objectives The aim of this study was to evaluate the cost-effectiveness of exposure in vivo (EXP, a cognitive-behavioral treatment targeting pain-related fear) in Complex Regional Pain Syndrome Type I (CRPS-I), as compared to pain-contingent physical therapy (PPT). Methods Data from a randomized controlled trial were used to compare the cost-effec...
Chapter
Het Complex Regionaal Pijn Syndroom type 1 (CRPS-I) gaat gepaard met verschillende lichamelijke verschijnselen. Er bestaat geen sluitende medische verklaring voor het syndroom. Wel is duidelijk dat bij de instandhouding van de vaak enorme beperkingen die patiënten met CRPS-I ervaren, pijngerelateerde angst een rol kan spelen. Onderzoek laat inderda...
Chapter
Patiënten blijken te leren van eigen ervaringen en door informatie van anderen, maar ook op basis van observatie. De groepsbehandeling werd ontwikkeld op basis van de verwachting dat het observeren van een medepatiënt een sterkere leerervaring kan geven dan het observeren van de behandelaar, en dat groepsdynamiek het herkennen van irreële cognities...
Chapter
In dit hoofdstuk wordt beschreven hoe de behandelaar de patiënt uitleg kan geven over zijn pijnprobleem. Ook worden de consequenties besproken die dit heeft voor de graded-exposurebehandeling, waarbij de patiënt zal worden uitgedaagd activiteiten en bewegingen uit te voeren die hij eigenlijk niet goed durft uit te voeren. Omdat hij negatieve verwac...
Chapter
Nadat met behulp van de PHODA zowel een individuele hiërarchie van gevreesde activiteiten is verkregen als inzicht in irreële cognities ten aanzien van schadelijkheid van activiteiten, wordt de educatie gegeven. Na de educatie volgen de praktische sessies graded exposure. In deze sessies worden gedragsexperimenten vormgegeven. Het doel van deze exp...
Article
Full-text available
Background: Following lumbar fusion surgery, a successful outcome is empirically linked to effective rehabilitation. While rehabilitation is typically postoperative, the phase before surgery - termed prehabilitation - is reportedly an ideal time to prepare the patient. There are presently no guidelines for prehabilitation before lumbar fusion surg...
Article
Full-text available
Complex regional pain syndrome type I (CRPS-I) highly affects patients' ability to perform daily life activities. Pain-related fear might be a key target to reduce disability in chronic pain. Current treatments aiming at reducing pain show little improvements on pain and disability, whereas novel exposure-based treatments targeting pain-related fea...
Article
Biopsychosocial interventions provided in multidisciplinary settings are promising for improving functional disability levels in patients with chronic low back pain (CLBP). These multidisciplinary biopsychosocial interventions mainly focus on cognitive-behavioural approaches that aim to change negative cognitions, emotions, behaviour, work and soci...
Article
Objective The experiential acquisition of pain-related fear has been demonstrated by pairing a painful electrocutaneous stimulus (pain-US) with one movement (CS+) but not with another (CS-). However, it is expected that during acquisition through direct experience, pain-related fear can be intensified or weakened by verbally/visually transmitted i...
Article
Background and aims: Graded exposure in vivo (GEXP) specifically targets at pain-related fear and has been successfully applied in Complex Regional Pain Syndrome Type I (CRPS-I), reducing pain-related fear, disability, pain intensity and physiological signs and symptoms. So far, no results on GEXP in children have been published. Since the Dutch gu...
Article
Acute pain informs the individual that there is an imminent threat of body damage, and is associated with the urge to escape and avoid. Fear learning takes place when neutral stimuli receive the propensity to predict the occurrence of pain, and when defensive responses are initiated in anticipation of potential threats to the integrity of the body....
Article
Fear of (re)injury/movement has been identified as a potential predictor of chronic disability in complex regional pain syndrome type I (CRPS-I). In order to reduce pain-related fears and pain disability, graded exposure in vivo (GEXP) is likely to be an appropriate treatment. Indeed, there is evidence that in chronic pain patients reporting substa...
Article
Full-text available
Uit onderzoek blijkt inderdaad dat bij patiënten met chronische pijn aan het bewegingsapparaat pijngerelateerde vrees en daarmee samenhangend vermijdingsgedrag meer bepalend is voor de beperkingen op activiteitenniveau dan de pijnintensiteit. 2-5 Pijngerelateerde vrees gaat samen met een verhoogde mate van specifieke bezorgdheid en catastrofaal den...

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Project
Following lumbar fusion surgery, a successful outcome is empirically linked to effective rehabilitation. While rehabilitation is typically postoperative, the phase before surgery – termed prehabilitation – is reportedly an ideal time to prepare the patient. There are presently no guidelines for prehabilitation before lumbar fusion surgery. Physical activity has well-known health benefits, and staying physically active despite pain is a major principle in non-pharmacological chronic low back pain treatment. Psychological factors such as fear of movement, pain catastrophizing and low self-efficacy are known to be barriers to staying active. No studies have investigated prehabilitation protocols that promote physical activity and target psychological risk factors before lumbar fusion surgery. The aim of our proposed randomised controlled trial is to investigate whether patients who undergo lumbar fusion surgery for degenerative disc disease experience better functioning with a physiotherapeutic prehabilitation program (PREPARE) based on a cognitive behavioural approach compared to conventional care.