Markus Zedler

Markus Zedler
Hannover Medical School | MHH

22.43
 · 
Dr. med.

About

37
Publications
6,871
Reads
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577
Citations
Research Experience
January 2011 - present
Hannover Medical School
Position
January 2011 - present
Leibniz Institute for Neurobiology
Position
March 2003 - March 2003
Hannover Medical School
Position
  • 1st Int. Conference on Synaesthesia
Description
  • Idee und Konzeption des ersten interdisziplinären Kongresses in der Synästhesieforschung mit Unterstützung der DFG. Wissenschaftliche Leitung Prof. Dr. Dr. Hinderk Emrich.
Education
August 2014 - December 2015
Technische Universität Braunschweig
Field of study
  • Further training in didactics for university teachers
March 2007 - June 2008
Hannover School of Health Management (HSHM)
Field of study
  • Basics and Advanced Health Management

Publications

Publications (37)
Article
Judgments about personalities and social traits can be made by relatively brief exposure to animate living things. Here we show that unusual architecture in the microstructure of the human brain is related to atypical mental projections of personality and social structure onto things that are neither living nor animate. Our participants experience...
Article
Full-text available
Introduction. Synaesthesia is a phenomenon in which a certain stimulus induces a concurrent sensory perception; it has an estimated prevalence of 4 %. Sexual arousal as an inducer for synaesthetic perceptions is rarely mentioned in the literature but can be found sometimes in case reports about subjective orgasmic experiences. Aims. To examine whet...
Article
Full-text available
Synästhesie ist eine gesunde Normvariante menschlichen Bewusstseins und tritt bei ca. 5 % der Bevölkerung als Kopplung von Sinnesqualitäten auf, die in der Regel mit deutlich mehr kognitiven und seelischen Vorteilen als mit Beeinträchtigungen einhergeht. Auf vielleicht über 150 mögliche verschiedene Arten (6, 7) sind Sinne (auch im weiteren Sinne)...
Chapter
Subtitles: Mental Protection by Synesthesia; When Synesthetes Meet with Psychiatrists; Synesthesia as an Advantage; Loneliness; Synesthetes in Conflicts; Social Interactions; Synesthesia Under Stressful Conditions; Narcissism; Sexuality; Empathy and Lucidity.
Article
In auditory-visual synaesthesia, all kinds of sound can induce additional visual experiences. To identify the brain regions mainly involved in this form of synaesthesia, functional magnetic resonance imaging (fMRI) has been used during non-linguistic sound perception (chords and pure tones) in synaesthetes and non-synaesthetes. Synaesthetes showed...
Poster
Full-text available
Introducing the investigation of neurotrophic growth factor serum levels in synesthetes.
Poster
Full-text available
Open questionnaire trial on individual advantages of synaesthesia (Spanish)
Article
Full-text available
Neurobiological aspects of synaesthesia are discussed from the perspective of the broader philosophical topic of “syn-aisthesis” and the basic fundamentals of a neuropsychological understanding of perceptual inter-modal integration. Herein, the predominance of conceptualization processes in regard to top-down functions of the brain appears as a pre...
Article
Recent research suggests synesthesia as a result of a hypersensitive multimodal binding mechanism. To address the question whether multimodal integration is altered in synesthetes in general, grapheme-colour and auditory-visual synesthetes were investigated using speech-related stimulation in two behavioural experiments. First, we used the McGurk i...
Article
Full-text available
There is increasing evidence from case reports that synesthesia is more common in individuals with autism spectrum conditions (ASC). Further, genes related to synesthesia have also been found to be linked to ASC and, similar to synaesthetes, individuals with ASC show altered brain connectivity and unusual brain activation during sensory processing....
Article
Neurobiological aspects of synaesthesia are discussed from the perspective of the broader philosophical topic of “syn-aisthesis” and the basic fundamentals of a neuropsychological understanding of perceptual inter-modal integration. Herein, the predominance of conceptualization processes in regard to top-down functions of the brain appears as a pre...
Article
Grapheme-color synesthesia is a condition in which letters are perceived with an additional color dimension. To identify brain regions involved in this type of synesthesia and to analyze functional connectivity of these areas, 18 grapheme-color synesthetes and 18 matched controls were stimulated with letters and pseudo-letters presented in black an...
Article
It has been suggested that synaesthesia is the result of a hyper-sensitive multimodal binding-mechanism. To address the question whether multi-modal integration is altered in synaesthetes in general, grapheme-colour and auditory-visual synaesthetes were studied using the double-flash illusion. This illusion is induced by a single light flash presen...
Article
Despite some principal similarities, there is no systematic comparison between the different types of synesthesia (genuine, acquired and drug-induced). This comprehensive review compares the three principal types of synesthesia and focuses on their phenomenological features and their relation to different etiological models. Implications of this co...
Article
In synesthesia, certain stimuli to one sensory modality lead to sensory perception in another unstimulated modality. In addition to other models, a two-stage model is discussed to explain this phenomenon, which combines two previously formulated hypotheses regarding synesthesia: direct cross-activation and hyperbinding. The direct cross-activation...
Article
Color percept induction in synaesthetes by hearing words was previously shown to involve activation of visual and specifically color processing cortex areas. While this provides a rationale for the origin of the anomalous color percept the question of mechanism of this crossmodal activation remains unclear. We pursued this question with fMRI in col...
Article
Full-text available
Objective. Foreign body ingestion can be a challenge to multiprofessional approaches involving medical, surgical, neurological, and psychiatric teams.Case presentation. A 41-year-old male patient with intellectual disabilities presented after having swallowed approximately 20 sharp objects. While admitted to a psychiatric ward, surgeons removed a g...
Article
Background and Objectives: With the Cyberspace´s exponential growth of influence questions arise about its mental impacts. The presented study examines the question whether the dependent use of the Internet can be understood as an impulse control disorder, an addiction or as a symptom of other psychiatric conditions. Methods: Internet dependent pa...
Article
Full-text available
Objetivos: El trastorno por déficit de atención con hiperactividad (TDAH) tiene una gran importancia clínica no sólo por su elevada prevalencia sino también por su frecuente comorbilidad con enfermedades que están relacionadas con este trastorno. Diversos estudios han sido capaces de demostrar que el TDAH constituye un importante factor de riesgo p...
Article
Full-text available
Attention-deficit/hyperactivity disorder (ADHD) is of great clinical importance not only because of its high prevalence but also due to the frequent comorbid illnesses that are connected with this disorder. Several studies were able to demonstrate that ADHD constitutes a significant risk factor for the exacerbation of habit-forming illnesses, i.e....
Article
Attention deficit/hyperactivity disorder (ADHD) is a widely examined disease in childhood. There is evidence that the disease responds well to medication with methylphenidate (MPH). The effect of MPH in adults with ADHD is a question that is often raised, because many adults request such therapy today. As yet, there is a lack of studies on event-re...
Article
OBJECTIVE In psychiatric contexts, the quick distribution of virtual techniques in private and professional everyday life gives rise to the question, if these can evoke a psychological addiction. Yet, the diagnostic assessment of internet or computer game dependency remains problematic. METHODS Within a study with 23 internet-dependent patients wit...
Article
In psychiatric contexts, the quick distribution of virtual techniques in private and professional everyday life gives rise to the question, if these can evoke a psychological addiction. Yet, the diagnostic assessment of internet or computer game dependency remains problematic. Within a study with 23 internet-dependent patients with significant psyc...
Article
Farben hören – Geschmack sehen: Synsthetiker erleben eine Vermischung ihrer Sinne. Die Erforschung dieses Phnomens liefert spannende Einblicke in die Art und Weise, wie Sinneseindrücke im menschlichen Gehirn verarbeitet werden. Synsthesie als Lebensform erweist sich als Paradigma eines Selbstverstndnisses des Menschen, jenseits einer Physik der Rev...
Article
Accidental intrarterial injections are not uncommon in medical treatments. This is also true for uncontrolled injections by drug-addicts. Since 2002 a number of 600 heavy opiate addicts in Germany are substituted in a country-wide study with pure diacetylmorphine (Heroine). We report the course and outcome of three cases of accidental intraarterial...
Article
Die akzidentelle intraarterielle Injektion von Medikamenten und Begleitstoffen stellt eine nicht seltene medizinische Komplikation dar. Dies gilt auch fur unkontrollierte Autoinjektionen drogenabhangiger Patienten. Seit dem Jahre 2002 werden im Rahmen der bundesdeutschen Studie zur heroingestutzten Behandlung Opiatabhangiger ca. 600 Schwerstabhangi...
Article
Full-text available
When humans perceive an object, their perceptory organs transform the properties of the object into percepts of different modalities, which are then related with one another in such a way that the object appears as a unified entity in consciousness. This neurobiological process, which is still largely unknown, is called "binding". When during the p...
Article
Acamprosate is effective in reducing alcohol intake in weaned alcoholics. We were interested if acamprosate had an effect on the excitability of cortical motoneurons determined by transcranial magnetic stimulation (TMS). We studied 12 male healthy volunteers (mean age 29.5 years, SD = 4.8) who were either treated with 6 tablets of acamprosate (each...
Article
Several studies have shown acamprosate (calciumacetylhomotaurinate) to increase abstinence rates in weaned alcoholics. Chronic alcoholics often suffer from cognitive deficits. Since acamprosate appears to interact with N-methyl-D-aspartate (NMDA) receptors, a subclass of glutamate receptors playing an important role in learning and memory processes...
Article
The possible effects on psychomotor performance, concentration, attention, and mood of acamprosate (calciumacetylhomotaurinate) were assessed using a randomized, double-blind, cross-over, placebo-controlled design involving 12 healthy male volunteers. Acamprosate 2 g daily per os or placebo was administered for seven days and separated by washout i...

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