Markus Kersting

Markus Kersting
Hannover Medical School | MHH · Center for Information Management

Dr.

About

42
Publications
8,964
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187
Citations
Citations since 2017
8 Research Items
91 Citations
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201720182019202020212022202305101520
201720182019202020212022202305101520
Additional affiliations
July 2005 - present
Hannover Medical School
Position
  • IT-Manager

Publications

Publications (42)
Poster
Some University hospitals in Germany are hosting two large scale BMBF-funded projects at the same time: the Medical informatics initiative (MI-I) and the German Biobank Alliance (GBA). One of them is Hannover Medical School (MHH). To highlight, coordinate and implement synergy effects in these projects, both the MI-I and GBA have to harmonize their...
Conference Paper
The Hannover Medical School (MHH) has established the Hannover Unified Biobank (HUB), one of the largest university biobanks in Germany. In cooperation with the Institute of Pathology, approximately 1.2 million tissue samples and 960,000 liquid samples are stored and managed in the HUB. The Enterprise Clinical Research Data Warehouse (ECRDW) of th...
Poster
Full-text available
Bioprobendaten, verknüpft mit gesundheitsrelevanten Daten von Spendern, bilden die Grundlage für innovative biomedizinische Forschung. Die Menge an gelagerten Biomaterialien in Biobanken steigt stetig an. Oft ist die biobankrelevante Datenqualität sehr heterogen. Dadurch wird ein standortübergreifender Austausch von Bioproben und Daten zur Zusammen...
Chapter
Full-text available
Background: The Hannover Unified Biobank (HUB) stores bio samples from more than 130 research projects, some of the samples are processed in the HUB and some are stored directly. Effective transport and organized storage and retrieval with a high sample amount require electronic support which is mostly absent in current biobank IT systems [1,2]. Ai...
Conference Paper
Full-text available
Introduction: The reuse of electronic health records (EHR) data for research purposes has become an important topic in national discussion [1]. A typical large university hospital is characterized by a heterogeneous IT system landscape with clinical, laboratory and radiology information systems and further specialized information systems related to...
Conference Paper
Full-text available
Background: The Hannover Unified Biobank (HUB) located at the Hannover Medical School (MHH) and the clinical data warehouse of the MHH are linked and established as central service units for all research use cases regarding bio samples and data. Aim: Expand data linkage to OMICS use cases, higher integration in clinical routine processes, and effic...
Poster
Full-text available
Nach der erfolgreichen DIN ISO 9001 Zertifizierung der Biobankprozesse in 2015 beschäftigt sich die Hannover Unified Biobank (HUB), die zentrale Biobank der Medizinischen Hochschule Hannover (MHH) [1], nun mit der Frage, ob und wenn ja, welche Systeme in Biobanken validiert werden müssen, um den jeweiligen Ansprüchen der Zertifizierungs- bzw. Akkre...
Article
Background: Treatment recommendations in chronic lymphocytic leukemia (CLL) are based upon selected, otherwise healthy study populations mostly under 72 years of age. The Project group Internistic Oncology (PIO) embarked on an analysis of the 'real-world' safety and efficacy of bendamustine with and without rituximab in unselected outpatients. Pa...
Conference Paper
Full-text available
Die Versorgungsforschung als relativ junge Disziplin der Gesundheitssystemforschung untersucht methodisch bestehende Versorgungsstrukturen und –prozesse mit dem Ziel der Entwicklung und Evaluation neuer Versorgungskonzepte. Als wichtige Aspekte der Versorgungsforschung werden häufig die Nähe zum Alltag sowie die Patientenzentriertheit aufgeführt. „...
Article
Biobanks are the basis for a substantial part of biomedical research. The development, establishment and operation of biobanks are connected to a broad range of aspects, mainly concerning the preparation, storage, usage and dissemination of samples and associated data, in addition to the social and public involvement of these processes. These compl...
Conference Paper
Full-text available
The consistent and high samples quality of biomaterials from quality-assured biobanks makes these biological samples for research especially interesting. Certification processes of central clinical biobanks document these efforts to the outside clients. Certification and accreditation are here different procedures that support these quality assuran...
Conference Paper
Full-text available
Zusammenfassung. Hintergrund: Die Hannover Unified Biobank (HUB) verwaltet mehrere Lagerorte mit unterschiedlichsten Lagerstrukturen und – elementen. Die Abbildung von Lagern und deren Belegung ist eine komplex Aufgabe, die von den Herstellern der Biobank-/Laborinformationssysteme (BIMS) unterschiedlich gelöst wird. Für eine realitätsnahe Abbildung...
Conference Paper
Full-text available
In 2012 Hannover Medical School (MHH) founded a central harmonized and modern biobank, the Hannover Unified Biobank (HUB). After the establishment of a stable and highly modern biobanking infrastructure, the harmonization of biobanking and the creation of a reliable and safe sample and data management system, now an efficient sample and data qualit...
Conference Paper
Full-text available
Background: After a successful start the Hannover Unified Biobank (HUB) is expanding its infrastructure. Part of this process is the acquisition of new software components to support massive sample storage and data management. As a prequisite the requirements [1] were defined and an analysis of the German market for biobanking software [2] has been...
Article
Full-text available
Objective: To determine the frequency of potential drug-disease interaction in elderly patients in family practice. To assess which drugs and diagnoses are associated with a high risk related to drug-disease interaction and whether there are gender- or age-related differences. Methods: In routinely recorded electronic patient records, patients a...
Conference Paper
Full-text available
Hintergrund: Die MHH etabliert eine zentrale Biobank-Infrastruktur. Neben der zentralen Probenlagerung liegt das besondere Augenmerk auf der einheitlichen Erfassung der zu den Proben gehörigen Daten. Parallel zur prospektiven Einbindung der Biobank in überregionale Projekte (Deutsches Zentrum für Lungenforschung, Nationale Kohorte, …) existieren an...
Conference Paper
Full-text available
Large multinational studies form a specific challenge in the build-up of uniform biobanking procedures. In the international IMI (Innovative Medicines Initiative) FP 7 funded project COMBACTE (Combatting Bacterial Resistance in Europe) more than 100 clinical sites from Western and Eastern European countries are involved. The main aim of COMBACTE is...
Article
Full-text available
Background and aims: Health-care research is, besides primary acquired study data, based on data from widely differing secondary sources. In order to link, compare and analyze data sources uniform models and methods are needed. This could be facilitated by a more structured description of requirements, models and methods of health-care research th...
Article
Full-text available
Background: Physician Information Systems (AIS) are in use for organizing primary care patient management and to charge for services rendered. In addition, these systems offer even more options for use. The different functions of AIS and the extent to which these systems are in use at practice level are presented in this article. Method: Analysis o...
Conference Paper
Full-text available
Hintergrund Abbildung und Transport ärztlicher Routinedaten mittels Arztpraxis-Informationssystemen (AIS) oder Krankenhaus-Informationssysteme (KIS) ist in Deutschland heterogen. Für die Sekundärdatenforschung, insbesondere die Verknüpfung von Daten, wäre ein einheitliches Datenmodell vorteilhaft. Ziel Beschreibung der Anforderungen an ein allgemei...
Conference Paper
Full-text available
Einführung Die Nutzung von routinemäßig durch Hausärzte erhobenen und im Arztpraxisinformationssystem (AIS) elektronisch abgelegten Betreuungs- und Behandlungsdaten für Forschungszwecke ist prototypisch gelungen, dabei allerdings auf vielfältige Besonderheiten und unterschiedliche Schwierigkeiten gestoßen. Ziele: - Aspekte der Extraktion und wissen...
Article
Eine einheitliche und ausgereifte Informations- und Kommunikationstechnologie ist unerlässlich für die optimale Unterstützung zukünftiger Prozesse im Gesundheitswesen einschließlich der Versorgungsforschung. Sekundäranalysen von Routinedaten aus der ambulanten Primär- und Sekundärversorgung sind häufig auf die Untersuchung von Abrechnungsdaten begr...
Article
Full-text available
Vaccination against infection with human influenza virus is considered to be one of the most effective preventive measures available, especially when complications such as hospitalisation or death and indirect costs from off-work are considered. General practice is the preferable place for annual influenza vaccination because here the elderly and t...
Article
Full-text available
An advanced and integrative information technology (IT)-landscape is needed for optimal support of future processes in health-care, including health services research. Most researches in the primary care sector are based on data collected for reimbursement. The aim of this study is to show the limits and options of secondary analysis based on data...
Conference Paper
Full-text available
Hintergrund und Ziel Routinedaten aus vertragsärztlicher Praxis und Abrechnung werden zunehmend in gesundheitswissenschaftlichem Kontext und für Untersuchungen der Versorgungsforschung sekundär genutzt. Erfahrungen von Mitarbeitern des Instituts für Allgemeinmedizin der MHH seit 2005 bei der Gewinnung und Verwertung von vertragsärztlichen Versorgun...
Article
Background: This retrospective observational study presents the utilisation of preventive health examinations by members of the Statutory Health Insurance, as all are entitled from the age of 35 years onward, according to article 25 of the German Social Code Book Five. Methods: Data from family medicines' electronic patient records were extracted v...
Article
IntroductionDizziness can be due to multiple causes. However, the aetiology often remains unclear. At the same time, there is a lack of evidence-based treatment options. The aim of this study was to investigate the frequency of dizziness-related diagnoses, referrals and prescriptions in a general practice database.Methods Data from computerized pat...
Conference Paper
Full-text available
Article
Dizziness can be due to multiple causes. However, the aetiology often remains unclear. At the same time, there is a lack of evidence-based treatment options. The aim of this study was to investigate the frequency of dizziness-related diagnoses, referrals and prescriptions in a general practice database. Data from computerized patient records of 138...
Article
Home visits are an integral part of general practice. However, information on this subject is lacking in Germany. Therefore we aim to describe the quantity of home visits, the target population and the workload for general practitioners on the basis of computerised data routinely collected in general practices. The routine care data originate from...
Article
Full-text available
Einleitung: Hausbesuche sind ein wesentlicher Bestandteil allgemeinärztlicher Tätigkeit. Bisher liegen allerdings keine aktuellen Erkenntnisse zum Besuchsverhalten der Hausärzte in Deutschland vor, weshalb wir anhand von routinemäßig erhobenen Praxisdaten Zielpopulation, Arbeitsaufwand und Entwicklung der Besuchstätigkeit der letzten Jahre untersuc...

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Projects

Project (1)
Project
The aim is a developing of a central data integration and analyses plattform for secondary use of medical data (EHR, EMR) for research purposes