Mark Rodgers

Mark Rodgers
The University of York · Centre for Reviews and Dissemination

About

64
Publications
118,268
Reads
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5,667
Citations
Additional affiliations
January 2010 - present

Publications

Publications (64)
Article
Full-text available
Background The economic and social costs of autism are significant. This study evaluates the cost-effectiveness of early intensive Applied Behaviour Analysis (ABA)-based interventions for autistic pre-school children in the UK. Methods A de novo economic analysis was developed in Microsoft Excel comparing early intensive ABA-based interventions co...
Article
High prevalence of risk behaviours may exacerbate existing poor health in disadvantaged groups. We aimed to identify and bring together systematic reviews with a focus on reducing risk behaviours in disadvantaged groups and highlight where evidence is lacking. We searched MEDLINE and Embase up to October 2020, with supplementary searching in Episte...
Conference Paper
Background Lifestyle risk behaviours are associated with an increased risk of non-communicable disease and mortality. There are socio-economic inequalities in these behaviours, with some behaviours being more prevalent in particular groups, such as prisoners, homeless people and Gyspies, Travellers and Roma. The aim of this scoping review was to id...
Article
Background For systematic reviews to be rigorous, deliverable and useful, they need a well-defined review question. Scoping for a review also requires the specification of clear inclusion criteria and planned synthesis methods. Guidance is lacking on how to develop these, especially in the context of undertaking rapid and responsive systematic revi...
Article
Full-text available
Lay abstract: Early intensive applied behaviour analysis-based interventions are designed to support young autistic children's learning and development. Unfortunately, the available evidence about the effectiveness of these interventions remains unclear. Several reviews have focused on the published findings rather than contacting the authors to c...
Article
Background: The integration of care, particularly across the health and social care sectors, has been a long-standing policy objective in the UK. We sought to scope the evidence related to the regulation and inspection of integrated care. Objective(s): To identify and classify published material that could potentially address four key questions: 1....
Article
Full-text available
Background Early intensive applied behaviour analysis-based interventions are intensive interventions for autistic children that are often delivered on a one-to-one basis for 20–50 hours per week. Objectives To evaluate the clinical effectiveness and cost-effectiveness of early intensive applied behaviour analysis-based interventions for autistic...
Article
Background The health and well-being of staff working in the NHS is a significant issue for UK health care. We sought to identify research relevant to the promotion of healthy lifestyles among NHS staff on behalf of NHS England. Objectives To map existing reviews on workplace-based interventions to promote health and well-being, and to assess the...
Article
Background In ‘digital-first primary care’ models of health-care delivery, a patient’s first point of contact with a general practitioner or other health professional is through a digital channel, rather than a face-to-face consultation. Patients are able to access advice and treatment remotely from their home or workplace via a number of different...
Article
Background Police officers are often the first responders to mental health-related incidents and, consequently, can become a common gateway to care. The volume of such calls is an increasing challenge. Objective What is the evidence base for models of police-related mental health triage (often referred to as ‘street triage’) interventions? Design...
Article
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Background: Two UK academic centres were commissioned to provide a responsive rapid evidence synthesis service. The service covered topics identified by the National Institute for Health Research Health Services & Delivery Research (NIHR HSDR) programme as priorities for the National Health Service or to inform research commissioning. Aims and obje...
Article
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People with mental health conditions have a lower life expectancy and poorer physical health outcomes than the general population. Evidence suggests this is due to a combination of clinical risk factors, socioeconomic factors, and health system factors, notably a lack of integration when care is required across service settings. Several recent repo...
Article
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Background Psoriasis is a chronic inflammatory disease that predominantly affects the skin. Adalimumab (HUMIRA ® , AbbVie, Maidenhead, UK), etanercept (Enbrel ® , Pfizer, New York, NY, USA) and ustekinumab (STELARA ® , Janssen Biotech, Inc., Titusville, NJ, USA) are the three biological treatments currently licensed for psoriasis in children. Obje...
Article
Full-text available
Adults with autism spectrum disorder without intellectual impairment may benefit from a range of support services. This article presents the results of a systematic review assessing the effectiveness of supportive interventions for adults with autism spectrum disorder without intellectual impairment. A total of 32 studies were included; most focuse...
Technical Report
Background: Psoriasis is a chronic inflammatory disease that predominately affects the skin. Adalimumab, etanercept and ustekinumab are the three biologics currently licensed for psoriasis in children. Objective: To determine the clinical and cost-effectiveness of adalimumab, etanercept and ustekinumab within their respective licensed indications,...
Article
Background Organisational case study proposals can be poorly articulated and methodologically weak, raising the possible need for publication standards in this area. This rapid review and Delphi consensus process sought to develop reporting standards for organisational case study research, with particular application to the UK National Health Servi...
Article
Full-text available
Objective: To assess the accuracy of point-of-care testing for circulatory cathodic antigen in the diagnosis of schistosome infection. Methods: We searched MEDLINE, EMBASE, LILACS and other bibliographic databases for studies published until 30 September 2015 that described circulatory cathodic antigen testing compared against one to three Kato-...
Article
Full-text available
Objective To identify the main areas of uncertainty and subsequent research priorities to inform the ongoing debate around assisted dying. Design Two-round electronic modified Delphi consultation with experts and interested bodies. Setting and participants 110 groups and individuals interested in the subject of end-of-life care and/or assisted dyin...
Article
Full-text available
People with mental health conditions have a lower life expectancy and poorer physical health outcomes than the general population. Evidence suggests that this discrepancy is driven by a combination of clinical risk factors, socioeconomic factors and health system factors. Objective(s) To explore current service provision and map the recent evidenc...
Article
The National Institute for Health and Care Excellence (NICE) invited the manufacturer of ustekinumab (Janssen) to submit evidence for the clinical and cost effectiveness of ustekinumab for the treatment of active psoriatic arthritis (PsA) as part of the Institute's single technology appraisal (STA) process. The Centre for Reviews and Dissemination...
Article
Full-text available
Organisational case study proposals can be poorly articulated and methodologically weak, raising the possible need for publication standards in this area. Objectives To develop reporting standards for organisational case study research, with particular application to the UK National Health Service. Design Rapid evidence synthesis and Delphi conse...
Article
Background: The most effective sources to search to identify adverse effects data for medical devices are currently unknown. Methods: The included studies from a systematic review of the safety of recombinant human bone morphogenetic protein-2 (rhBMP-2) for spinal fusion were used for analysis. For each source searched, a record was made for eac...
Article
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Background Research has indicated that adverse effects terms are increasingly prevalent in the title, abstract or indexing terms of articles that contain adverse drug effects data in MEDLINE and Embase. However, it is unknown whether adverse effects terms are present in the database records of articles that contain adverse effects data of medical d...
Article
Full-text available
Pressure ulcers affect around 5% of patients: but the majority of these may be avoidable ▀ Pressure ulcers can become painful, infected and malodorous, reduce health related quality of life and increase length of hospital stay ▀ Multicomponent interventions are recommended, incorporating: pressure-relieving surfaces, skin inspections, repositioni...
Article
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Background The grading of recommendation, assessment, development and evaluation (GRADE) approach is widely implemented in health technology assessment and guideline development organisations throughout the world. GRADE provides a transparent approach to reaching judgements about the quality of evidence on the effects of a health care intervention,...
Article
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To investigate whether published results of industry funded trials of recombinant human bone morphogenetic protein 2 (rhBMP-2) in spinal fusion match underlying trial data by comparing three different data sources: individual participant data, internal industry reports, and publicly available journal publications and conference abstracts. The manuf...
Data
Full-text available
Overview of available sources of data for Metronic rhBMP-2
Data
Outcomes reported in peer reviewed journal articles compared with Medtronic internal reports
Data
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Adverse events occurring in Medtronic studies, as reported in published journal articles
Article
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Recombinant human bone morphogenetic protein-2 (rhBMP-2) is widely used to promote fusion in spinal surgery, but its safety has been questioned. To evaluate the effectiveness and safety of rhBMP-2. Individual-participant data obtained from the sponsor or investigators and data extracted from study publications identified by systematic bibliographic...
Article
The National Institute for Health and Clinical Excellence (NICE) invited the manufacturer of alitretinoin (Basilea Pharmaceuticals Ltd, Basel, Switzerland) to submit evidence for the clinical and cost effectiveness of this drug for the treatment of patients with severe chronic hand eczema (CHE), as part of the Institute’s single technology appraisa...
Article
Full-text available
Depression is the most common mental disorder in community settings and a major cause of disability across the world. The objective of treatment is to achieve remission or at least adequate control of depressive symptoms; however, even after successful treatment, the risk of relapse after remission is significant. Although the effectiveness of low-...
Article
Full-text available
A probabilistic model was developed to determine the cost-effectiveness of three biologics, etanercept, infliximab and adalimumab, compared with palliative care for the treatment of active and progressive PsA in patients who have an inadequate response to standard treatment (including DMARDs). A previous model was revised to evaluate the impact of...
Article
Full-text available
This paper presents a summary of the evidence review group (ERG) report into the use of bevacizumab (Avastin®, Roche) in combination with a taxane for the treatment of untreated metastatic breast cancer (mBC). The main clinical effectiveness data were derived from a single, open-label randomised controlled trial (RCT) (E2100) that evaluated the add...
Article
This paper presents a summary of the evidence review group (ERG) report into the use of bevacizumab (Avastin ® , Roche) in combination with a taxane for the treatment of untreated metastatic breast cancer (mBC). The main clinical effectiveness data were derived from a single, open-label randomised controlled trial (RCT) (E2100) that evaluated the a...
Article
Full-text available
Etanercept, infliximab and adalimumab are licensed in the UK for the treatment of active and progressive psoriatic arthritis (PsA) in adults who have an inadequate response to standard treatment. To determine the clinical effectiveness, safety and cost-effectiveness of these biologic agents in the treatment of active and progressive PsA. Systematic...
Article
This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of alitretinoin for the treatment of adults with severe chronic hand eczema refractory to topical steroid treatment in accordance with the licensed indication, based upon the evidence submission from Basilea Pharmaceuticals...
Article
Full-text available
The National Institute for Health and Clinical Excellence (NICE) invited the manufacturer of alitretinoin (Basilea Pharmaceuticals Ltd, Basel, Switzerland) to submit evidence for the clinical and cost effectiveness of this drug for the treatment of patients with severe chronic hand eczema (CHE), as part of the Institute’s single technology appraisa...
Article
Full-text available
This paper presents a summary of the evidence review group (ERG) report into the clinical effectiveness and cost-effectiveness of alitretinoin for the treatment of adults with severe chronic hand eczema refractory to topical steroid treatment in accordance with the licensed indication, based upon the evidence submission from Basilea Pharmaceuticals...
Article
Full-text available
To determine the diagnostic performance and cost-effectiveness of colour vision testing (CVT) to identify and monitor the progression of diabetic retinopathy (DR). Major electronic databases including MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature, and Cochrane Database of Systematic Reviews were searched from inception t...
Article
Case series can influence clinical practice but are often omitted from systematic reviews. We evaluated the contribution of case series to a systematic review of radiofrequency catheter ablation (RFCA) for treatment of atrial fibrillation (AF). Analysis of the results of a systematic review based on a search of 25 electronic databases and Internet...
Article
Full-text available
To assess the cost-effectiveness of radiofrequency catheter ablation (RFCA) compared with anti-arrhythmic drug (AAD) therapy for the treatment of atrial fibrillation (AF) from the perspective of the UK NHS. Bayesian evidence synthesis and decision analytical model. A systematic review and meta-analysis was conducted and Bayesian statistical methods...
Article
Full-text available
The objective was to assess the impact of new guidance on the conduct of narrative synthesis in systematic reviews of effectiveness, by means of a blinded comparison of guidance-led narrative synthesis against a meta-analysis of the same study data.The conclusions of the two syntheses were broadly similar. However, differences between the approache...
Article
Full-text available
To determine the safety, clinical effectiveness and cost-effectiveness of radio frequency catheter ablation (RCFA) for the curative treatment of atrial fibrillation (AF) and typical atrial flutter. For the systematic reviews of clinical studies 25 bibliographic databases and internet sources were searched in July 2006, with subsequent update search...
Conference Paper
Purpose: To assess the cost-effectiveness and value of information of radiofrequency catheter ablation (RFCA) compared with anti-arrhythmic drug (AAD) therapy for the treatment of atrial fibrillation (AF) from the perspective of the UK NHS. Methods: A probabilistic model was constructed to estimate costs and quality-adjusted life years (QALYs) of R...
Article
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In the context of systematic reviews, statistical meta-analysis of findings is not always possible. Where this is the case, or where a review of implementation evidence is required, narrative synthesis of data is typically undertaken. Drawing on recently developed guidance aimed at those undertaking data synthesis – and information on the implement...
Article
Full-text available
To determine the most effective diagnostic strategy for the investigation of microscopic and macroscopic haematuria in adults. Electronic databases from inception to October 2003, updated in August 2004. A systematic review was undertaken according to published guidelines. Decision analytic modelling was undertaken, based on the findings of the rev...
Article
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Referencing once-confidential tobacco industry documents, we compare reviews of the epidemiological literature concerning tobacco harm that were carried out by the U.S. Tobacco Industry Research Committee (T.I.R.C.) and the U.S. Public Health Service and related groups during the 1950s and early 1960s. Results show that the T.I.R.C. operated an unb...
Article
OBJECTIVE: To conduct a review of existing systematic reviews, in order to (i) examine the types of psychosocial interventions that have been used with people suffering from heart disease or cancer, (ii) evaluate the effects of such interventions on physical outcomes, psychological outcomes or health care usage, and (iii) evaluate the methodologic...
Article
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No abstract available.
Article
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prevention. •B oth syntheses suggested that including previously-injured children in a trial might moderate the effectiveness of a safety education intervention. •T he narrative synthesis led to recommendations for future research relating to improvements in outcome measurement, description of interventions, use of theory in designing interventions...

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