Marjolein Orije

Ghent University | UGhent

Purpose To assess experiences of sexuality and of receiving sexual healthcare in cervical cancer (CC) survivors. Methods A qualitative phenomenological study using semistructured one-on-one interviews was conducted with 15 Belgian CC survivors recruited in 5 hospitals from August 2021 to February 2022. The interviews were audiotaped and transcribe...

Purpose To compare sexual/vaginal functioning between early cervical cancer (ECC) and locally advanced cervical cancer (LACC) survivors. Methods VAMOS was a multicenter, cross-sectional, questionnaire, noninferiority study including ECC patients treated with surgery and, if clinically indicated, adjuvant (chemo)radiotherapy and LACC patients treat...

Vaccination during pregnancy is effective in providing protection against vaccine-preventable diseases in young infants. Here, timely (second rather than third trimester) pertussis vaccination during pregnancy is recommended, conveying protection against Bordetella pertussis in both term and preterm born infants. Additionally, breastfeeding during...

Background Vaccination during pregnancy with tetanus, diphtheria, acellular pertussis (aP) (Tdap) antigens is important for early protection of newborn infants against pertussis, particularly for preterm infants. This study evaluated the effect of Tdap vaccination during pregnancy on the immunogenicity of a diphtheria (D), tetanus (T), aP, inactiva...

Introduction Maternal antibody interference of the infant’s humoral immune responses raises some concern to the strategy of maternal Tdap (tetanus, diphtheria, acellular pertussis [aP]) vaccination. This study assessed the impact of maternal Tdap antibodies on the infant’s pertussis-specific T lymphocyte responses following infant vaccination with...

Background Limited data exist on the impact of maternal Tetanus, Diphtheria, acellular Pertussis (aP) (Tdap) vaccination for preterm born infants. We report its effect at birth and on antibody-mediated immune responses to a DTaP-IPV-HB-PRP~T vaccine in preterm compared to term infants. Methods Women delivering at term or prematurely were either va...

Vaccines protect humans against microorganisms that cause disease. Usually, vaccines are given to infants, toddlers, or older children at regular intervals. For example, you probably know about the tetanus vaccine, which is given to you when you are hurt, or beforehand, to protect you from disease in case you get hurt. Maternal immunization means v...

Introduction/Background & Aims Enrichment of breast milk (BM) with immunoglobin (Ig)A and IgG, through maternal vaccination, could help young infants combat targeted pathogens. However, evidence on this effect after preterm delivery is lacking. This study investigated the total and anti-pertussis toxin (anti-PT) specific IgA and IgG production in B...

Immunizing pregnant women to protect the mother, fetus and infant from infection has increasingly been used over the last decade. Protection against infectious diseases in neonates is mainly provided by maternal antibodies transferred from mother to infant during pregnancy through transplacental transport or after delivery via breastfeeding. Both t...

During the last few decades, maternal immunization as a strategy to protect young infants from infectious diseases has been increasingly recommended, yet some issues have emerged. Studies have shown that for several vaccines, such as live attenuated, toxoid and conjugated vaccines, high maternal antibody titers inhibit the infant's humoral immune r...